Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides

Diabetes

Volumn 62, Issue 2, 2013, Pages 510-518

  Fukami, Ayako ^a   Seino, Yusuke ^a,b   Ozaki, Nobuaki ^a,c   Yamamoto, Michiyo ^c   Sugiyama, Chisato ^c   Sakamoto Miura, Eriko ^a   Himeno, Tatsuhito ^a   Takagishi, Yoshiko ^c   Tsunekawa, Shin ^a   Ali, Safina ^d   Drucker, Daniel J ^d   Murata, Yoshiharu ^c   Seino, Yutaka ^e   Oiso, Yutaka ^a   Hayashi, Yoshitaka ^c  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

^d MOUNT SINAI HOSPITAL   (Canada)

^e KANSAI ELECTRIC POWER CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; GASTRIC INHIBITORY POLYPEPTIDE; GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR; GLUCAGON; GLUCOSE; HORMONE RECEPTOR; INSULIN; PROGLUCAGON; PROGLUCAGON DERIVED PEPTIDE; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INTRAPERITONEAL GLUCOSE TOLERANCE TEST; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALS; CYCLIC AMP; GASTRIC INHIBITORY POLYPEPTIDE; GENE DELETION; GENE KNOCK-IN TECHNIQUES; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; INCRETINS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; PEPTIDE FRAGMENTS; PROGLUCAGON; RECEPTORS, GASTROINTESTINAL HORMONE; RECEPTORS, GLUCAGON;

EID: 84873025669     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0294     Document Type: Article

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