Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes

Diabetologia

Volumn 57, Issue 9, 2014, Pages 1876-1883

  Omar, Bilal A ^a   Liehua, Liu ^b   Yamada, Yuchiro ^c   Seino, Yutaka ^d   Marchetti, Piero ^e   Ahren B ^a  

^a LUND UNIVERSITY   (Sweden)

^b THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^c AKITA UNIVERSITY   (Japan)

^d Kensai Electric Power Hospital   (Japan)

^e UNIVERSITY OF PISA   (Italy)

Author keywords

GLP 1; Insulin secretion; Islets of Langerhans; Obesity; Type 2 diabetes

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN; NVPDPP 728; UNCLASSIFIED DRUG; VILDAGLIPTIN; ADAMANTANE; NITRILE; PYRROLIDINE DERIVATIVE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INSULIN RELEASE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; SPECIES DIFFERENCE; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; CORRELATION ANALYSIS; IMMUNOREACTIVITY; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION;

ADAMANTANE; ANIMALS; DIABETES MELLITUS, TYPE 2; DIPEPTIDYL PEPTIDASE 4; FEMALE; GLUCOSE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; NITRILES; PYRROLIDINES;

EID: 84905576401     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3299-4     Document Type: Article

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