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Volumn 12, Issue 6, 2016, Pages 625-639

Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward

Author keywords

Diversity; dysbiosis; eczema; gut microbiome; hygiene hypothesis; primary prevention; probiotic

Indexed keywords

PROBIOTIC AGENT;

EID: 84961217412     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2016.1147955     Document Type: Review
Times cited : (45)

References (100)
  • 1
    • 84869421349 scopus 로고    scopus 로고
    • Metchnikoff and the microbiome
    • S.H.Podolsky Metchnikoff and the microbiome. The Lancet. 2012;24(380):1810–1811.
    • (2012) The Lancet , vol.24 , Issue.380 , pp. 1810-1811
    • Podolsky, S.H.1
  • 2
    • 84925310614 scopus 로고    scopus 로고
    • Natural environments, ancestral diets, and microbial ecology: is there a modern “paleo-deficit disorder”? Part II
    • A.C.Logan, M.A.Katzman, V.Balanza-Martinez. Natural environments, ancestral diets, and microbial ecology: is there a modern “paleo-deficit disorder”? Part II. J Physiol Anthropol. 2015;34:9.
    • (2015) J Physiol Anthropol , vol.34 , pp. 9
    • Logan, A.C.1    Katzman, M.A.2    Balanza-Martinez, V.3
  • 3
    • 67651171829 scopus 로고
    • Some biological effects of the digestive flora
    • R.Dubos, R.W.Schaedler. Some biological effects of the digestive flora. Am J Med Sci. 1962;244:265–271.
    • (1962) Am J Med Sci , vol.244 , pp. 265-271
    • Dubos, R.1    Schaedler, R.W.2
  • 4
    • 84871839253 scopus 로고    scopus 로고
    • Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases
    • S.L.Prescott. Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases. J Allergy Clin Immunol. 2013;131:23–30.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 23-30
    • Prescott, S.L.1
  • 5
    • 80052065175 scopus 로고    scopus 로고
    • Antibiotic overuse: Stop the killing of beneficial bacteria
    • M.Blaser. Antibiotic overuse: Stop the killing of beneficial bacteria. Nature. 2011;476:393–394.
    • (2011) Nature , vol.476 , pp. 393-394
    • Blaser, M.1
  • 6
    • 84920493187 scopus 로고    scopus 로고
    • The gut microbiota and inflammatory noncommunicable diseases: associations and potentials for gut microbiota therapies
    • C.E.West, H.Renz, M.C.Jenmalm, et al. The gut microbiota and inflammatory noncommunicable diseases: associations and potentials for gut microbiota therapies. J Allergy Clin Immunol. 2015;135:3–13.
    • (2015) J Allergy Clin Immunol , vol.135 , pp. 3-13
    • West, C.E.1    Renz, H.2    Jenmalm, M.C.3
  • 7
    • 84934987107 scopus 로고    scopus 로고
    • Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites
    • A.N.Thorburn, C.I.McKenzie, S.Shen, et al. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015;6:7320.•• In this experimental model, feeding mice a high-fiber diet induced a distinctive gut microbiota with higher levels of the short-chain fatty acid acetate. High fiber or acetate feeding led to marked suppression of allergic airways disease by enhanced T-regulatory cell numbers and function. In addition, high fiber/acetate feeding of pregnant mice suppressed the expression of certain genes in the mouse fetal lung linked to both human asthma and experimental allergic airways disease. The authors concluded that a diet influencing the gut microbiota may represent a strategy to prevent asthma, also in pregnancy.
    • (2015) Nat Commun , vol.6 , pp. 7320
    • Thorburn, A.N.1    McKenzie, C.I.2    Shen, S.3
  • 8
    • 84897138296 scopus 로고    scopus 로고
    • Role of the microbiota in immunity and inflammation
    • Y.Belkaid, T.W.Hand. Role of the microbiota in immunity and inflammation. Cell. 2014;157:121–141.
    • (2014) Cell , vol.157 , pp. 121-141
    • Belkaid, Y.1    Hand, T.W.2
  • 9
    • 79959935088 scopus 로고    scopus 로고
    • Childhood immune maturation and allergy development: regulation by maternal immunity and microbial exposure
    • M.C.Jenmalm. Childhood immune maturation and allergy development: regulation by maternal immunity and microbial exposure. Am J Reprod Immunol. 2011;66 Suppl 1(Suppl 1):75–80.
    • (2011) Am J Reprod Immunol , vol.66 Suppl 1 , pp. 75-80
    • Jenmalm, M.C.1
  • 10
    • 84919709430 scopus 로고    scopus 로고
    • The gut microbiota and its role in the development of allergic disease: a wider perspective
    • C.E.West, M.C.Jenmalm, S.L.Prescott. The gut microbiota and its role in the development of allergic disease: a wider perspective. Clin Exp Allergy. 2015;45:43–53.
    • (2015) Clin Exp Allergy , vol.45 , pp. 43-53
    • West, C.E.1    Jenmalm, M.C.2    Prescott, S.L.3
  • 11
    • 84901358163 scopus 로고    scopus 로고
    • The placenta harbors a unique microbiome
    • K.Aagaard, J.Ma, K.M.Antony, et al. The placenta harbors a unique microbiome. Sci Transl Med. 2014;6(237ra65).•• This study showed that low amounts of DNA from bacterial phyla are also found in the placenta of a healthy pregnancy and that these phyla are resembling those in the mouth and not the phyla present in closer anatomic regions, e.g. the vagina, gut, or on the skin.
    • (2014) Sci Transl Med , vol.6 , Issue.237ra65
    • Aagaard, K.1    Ma, J.2    Antony, K.M.3
  • 12
    • 84883186674 scopus 로고    scopus 로고
    • Mom knows best: the universality of maternal microbial transmission
    • L.J.Funkhouser, S.R.Bordenstein. Mom knows best: the universality of maternal microbial transmission. PLoS Biol. 2013;11:e1001631.
    • (2013) PLoS Biol , vol.11 , pp. e1001631
    • Funkhouser, L.J.1    Bordenstein, S.R.2
  • 13
    • 84874766374 scopus 로고    scopus 로고
    • Identification of intracellular bacteria in the basal plate of the human placenta in term and preterm gestations
    • M.J.Stout, B.Conlon, M.Landeau, et al. Identification of intracellular bacteria in the basal plate of the human placenta in term and preterm gestations. Am J Obstet Gynecol. 2013;208(3):226.e1-7.
    • (2013) Am J Obstet Gynecol , vol.208 , Issue.3
    • Stout, M.J.1    Conlon, B.2    Landeau, M.3
  • 14
    • 84920587175 scopus 로고    scopus 로고
    • Gut microbiota and allergy: the importance of the pregnancy period
    • T.R.Abrahamsson, R.Y.Wu, M.C.Jenmalm. Gut microbiota and allergy: the importance of the pregnancy period. Pediatr Res. 2015;77:214–219.
    • (2015) Pediatr Res , vol.77 , pp. 214-219
    • Abrahamsson, T.R.1    Wu, R.Y.2    Jenmalm, M.C.3
  • 15
    • 26444484367 scopus 로고    scopus 로고
    • Isolation of commensal bacteria from umbilical cord blood of healthy neonates born by cesarean section
    • E.Jimenez, L.Fernandez, M.L.Marin, et al. Isolation of commensal bacteria from umbilical cord blood of healthy neonates born by cesarean section. Curr Microbiol. 2005;51:270–274.
    • (2005) Curr Microbiol , vol.51 , pp. 270-274
    • Jimenez, E.1    Fernandez, L.2    Marin, M.L.3
  • 16
    • 84875150368 scopus 로고    scopus 로고
    • Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months
    • M.B.Azad, T.Konya, H.Maughan, et al. Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. Cmaj. 2013;185:385–394.
    • (2013) Cmaj , vol.185 , pp. 385-394
    • Azad, M.B.1    Konya, T.2    Maughan, H.3
  • 17
    • 84955721706 scopus 로고    scopus 로고
    • Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study
    • [Epub ahead of print], Sep
    • M.B.Azad, T.Konya, R.R.Persaud, et al. Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study. Bjog. 2015 [Sep28]; [Epub ahead of print].• This article documented altered gut microbial composition in full-term infants following intrapartum antibiotic prophylaxis, especially with emergency cesarean delivery. This dysbiosis persisted at 1 year of age only among infants who were not exclusively breastfed at age 3 months.
    • (2015) Bjog
    • Azad, M.B.1    Konya, T.2    Persaud, R.R.3
  • 18
    • 84929297936 scopus 로고    scopus 로고
    • Dynamics and stabilization of the human gut microbiome during the first year of life
    • F.Bäckhed, J.Roswall, Y.Peng, et al. Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe. 2015;17:690–703.•• This study assessed the gut microbiomes of mothers and their infants in their first year of life, showing that weaning induces maturation of the gut microbiota. Maturation of the infant gut microbiome was accompanied by shifts in nutrient and xenobiotic metabolism.
    • (2015) Cell Host Microbe , vol.17 , pp. 690-703
    • Bäckhed, F.1    Roswall, J.2    Peng, Y.3
  • 19
    • 84924200429 scopus 로고    scopus 로고
    • Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity
    • S.Dogra, O.Sakwinska, S.-E.Soh, et al. Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity. MBio. 2015;6(1):e02419-14.
    • (2015) MBio , vol.6 , Issue.1
    • Dogra, S.1    Sakwinska, O.2    Soh, S.-E.3
  • 20
    • 84890461111 scopus 로고    scopus 로고
    • Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section
    • H.E.Jakobsson, T.R.Abrahamsson, M.C.Jenmalm, et al. Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section. Gut. 2014;63:559–566.• This study showed that children born through cesarean section had lower total microbiota diversity in infancy than vaginally delivered children. Persistent changes in the gut microbiota were demonstrated up to 2 years of age, particularly a decreased diversity of the Bacteroidetes phylum among cesarean-delivered children. Cesarean delivery was associated with a delayed maturation of Th1-associated immunity.
    • (2014) Gut , vol.63 , pp. 559-566
    • Jakobsson, H.E.1    Abrahamsson, T.R.2    Jenmalm, M.C.3
  • 21
    • 84883225829 scopus 로고    scopus 로고
    • Establishment of the intestinal microbiota and its role for atopic dermatitis in early childhood
    • J.Penders, K.Gerhold, E.E.Stobberingh, et al. Establishment of the intestinal microbiota and its role for atopic dermatitis in early childhood. J Allergy Clin Immunol. 2013;132:601–7 e8.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 601-7 e8
    • Penders, J.1    Gerhold, K.2    Stobberingh, E.E.3
  • 22
    • 80055088365 scopus 로고    scopus 로고
    • Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy
    • F.A.Van Nimwegen, J.Penders, E.E.Stobberingh, et al. Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy. J Allergy Clin Immunol. 2011;128:948-55 e1-3.
    • (2011) J Allergy Clin Immunol , vol.128
    • Van Nimwegen, F.A.1    Penders, J.2    Stobberingh, E.E.3
  • 23
    • 84926501106 scopus 로고    scopus 로고
    • Administration of a multistrain probiotic product (VSL#3) to women in the perinatal period differentially affects breast milk beneficial microbiota in relation to mode of delivery
    • P.Mastromarino, D.Capobianco, A.Miccheli, et al. Administration of a multistrain probiotic product (VSL#3) to women in the perinatal period differentially affects breast milk beneficial microbiota in relation to mode of delivery. Pharmacol Res. 2015;95-96:63–70.• This is the first article to show an alteration in breast milk lactobacilli and bifidobacteria with maternal probiotic treatment seen after vaginal but not cesarean delivery.
    • (2015) Pharmacol Res , vol.95-96 , pp. 63-70
    • Mastromarino, P.1    Capobianco, D.2    Miccheli, A.3
  • 25
    • 77956307084 scopus 로고    scopus 로고
    • Comparative analysis of fecal microbiota in infants with and without eczema
    • P.-Y.Hong, B.W.Lee, M.Aw, et al. Comparative analysis of fecal microbiota in infants with and without eczema. PLoS One. 2010;5:e9964.
    • (2010) PLoS One , vol.5 , pp. e9964
    • Hong, P.-Y.1    Lee, B.W.2    Aw, M.3
  • 26
    • 84945547238 scopus 로고    scopus 로고
    • Long term development of gut microbiota composition in atopic children: impact of probiotics
    • 9 CFU each daily) 6 weeks before delivery and then directly to infants for 12 months were evaluated up to 6 years of age in this study. The supplemented probiotic strains were detected in fecal samples during the intervention, but did not clearly affect gut microbiota composition and diversity. Interestingly, gut microbiota development continued between 2 and 6 years, then approaching a more adult-like composition.
    • (2015) PLoS One , vol.10 , pp. e0137681
    • Rutten, N.B.1    Gorissen, D.M.2    Eck, A.3
  • 27
    • 58449119188 scopus 로고    scopus 로고
    • Establishment of the gut microbiota in Western infants
    • I.Adlerberth, A.E.Wold. Establishment of the gut microbiota in Western infants. Acta Paediatr. 2009;98:229–238.
    • (2009) Acta Paediatr , vol.98 , pp. 229-238
    • Adlerberth, I.1    Wold, A.E.2
  • 28
    • 84887960425 scopus 로고    scopus 로고
    • Intestinal microbial diversity during early-life colonization shapes long-term IgE levels
    • J.Cahenzli, Y.Koller, M.Wyss, et al. Intestinal microbial diversity during early-life colonization shapes long-term IgE levels. Cell Host Microbe. 2013;14:559–570.
    • (2013) Cell Host Microbe , vol.14 , pp. 559-570
    • Cahenzli, J.1    Koller, Y.2    Wyss, M.3
  • 29
    • 0031571230 scopus 로고    scopus 로고
    • The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
    • N.Sudo, S.Sawamura, K.Tanaka, et al. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol. 1997;159:1739–1745.
    • (1997) J Immunol , vol.159 , pp. 1739-1745
    • Sudo, N.1    Sawamura, S.2    Tanaka, K.3
  • 30
    • 84860216630 scopus 로고    scopus 로고
    • Microbial exposure during early life has persistent effects on natural killer T cell function
    • T.Olszak, D.An, S.Zeissig, et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science. 2012;336:489–493.
    • (2012) Science , vol.336 , pp. 489-493
    • Olszak, T.1    An, D.2    Zeissig, S.3
  • 31
    • 84892774558 scopus 로고    scopus 로고
    • Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells
    • D.An, S.F.Oh, T.Olszak, et al. Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells. Cell. 2014;156:123–133.•• In this murine model, inhibitory sphingolipids from Bacteroides fragilis (B. fragilis) modified the homeostasis of host iNKT cells, effectively limiting iNKT cell proliferation during neonatal development and restricting total colonic iNKT cell numbers into adulthood. B. fragilis colonized hosts were protected against experimental iNKT cell-mediated, oxazolone-induced colitis. When germ-free pregnant dams were cohoused with B. fragilis monocolonized mice before delivery, the offspring’s colonic iNKT cell numbers were not normalized to the level observed when germ-free dams were mated with B. fragilis monocolonized mice, although at time of delivery, the mother was heavily colonized with B. fragilis bacteria. Thus, presence of B. fragilis during a prolonged prenatal period seemed to be required for achieving iNKT cell homeostasis.
    • (2014) Cell , vol.156 , pp. 123-133
    • An, D.1    Oh, S.F.2    Olszak, T.3
  • 32
    • 84874692225 scopus 로고    scopus 로고
    • The gut microbiota and mucosal homeostasis: colonized at birth or at adulthood, does it matter?
    • S.El Aidy, G.Hooiveld, V.Tremaroli, et al. The gut microbiota and mucosal homeostasis: colonized at birth or at adulthood, does it matter? Gut Microbes. 2013;4:118–124.
    • (2013) Gut Microbes , vol.4 , pp. 118-124
    • El Aidy, S.1    Hooiveld, G.2    Tremaroli, V.3
  • 33
    • 84865339630 scopus 로고    scopus 로고
    • A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development
    • M.Yamamoto, R.Yamaguchi, K.Munakata, et al. A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development. BMC Genomics. 2012;13:335.
    • (2012) BMC Genomics , vol.13 , pp. 335
    • Yamamoto, M.1    Yamaguchi, R.2    Munakata, K.3
  • 34
    • 84858956036 scopus 로고    scopus 로고
    • Patterns of early gut colonization shape future immune responses of the host
    • C.H.Hansen, D.S.Nielsen, M.Kverka, et al. Patterns of early gut colonization shape future immune responses of the host. PLoS One. 2012;7:e34043.
    • (2012) PLoS One , vol.7 , pp. e34043
    • Hansen, C.H.1    Nielsen, D.S.2    Kverka, M.3
  • 35
    • 84873947592 scopus 로고    scopus 로고
    • Timing of allergy-preventive and immunomodulatory dietary interventions - are prenatal, perinatal or postnatal strategies optimal?
    • M.C.Jenmalm, K.Duchen. Timing of allergy-preventive and immunomodulatory dietary interventions - are prenatal, perinatal or postnatal strategies optimal? Clin Exp Allergy. 2013;43:273–278.
    • (2013) Clin Exp Allergy , vol.43 , pp. 273-278
    • Jenmalm, M.C.1    Duchen, K.2
  • 36
    • 78649512314 scopus 로고    scopus 로고
    • Farm living: effects on childhood asthma and allergy
    • E.Von Mutius, D.Vercelli. Farm living: effects on childhood asthma and allergy. Nat Rev Immunol. 2010;10:861–868.
    • (2010) Nat Rev Immunol , vol.10 , pp. 861-868
    • Von Mutius, E.1    Vercelli, D.2
  • 37
    • 34247502904 scopus 로고    scopus 로고
    • Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial
    • T.R.Abrahamsson, T.Jakobsson, M.F.Böttcher, et al. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2007;119:1174–1180.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1174-1180
    • Abrahamsson, T.R.1    Jakobsson, T.2    Böttcher, M.F.3
  • 38
    • 77955856378 scopus 로고    scopus 로고
    • Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial
    • C.K.Dotterud, O.Storro, R.Johnsen, et al. Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial. Br J Dermatol. 2010;163:616–623.
    • (2010) Br J Dermatol , vol.163 , pp. 616-623
    • Dotterud, C.K.1    Storro, O.2    Johnsen, R.3
  • 39
    • 0035820307 scopus 로고    scopus 로고
    • Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial
    • M.Kalliomäki, S.Salminen, H.Arvilommi, et al. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet. 2001;357:1076–1079.
    • (2001) Lancet , vol.357 , pp. 1076-1079
    • Kalliomäki, M.1    Salminen, S.2    Arvilommi, H.3
  • 40
    • 33845951414 scopus 로고    scopus 로고
    • Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial
    • K.Kukkonen, E.Savilahti, T.Haahtela, et al. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol. 2007;119:192–198.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 192-198
    • Kukkonen, K.1    Savilahti, E.2    Haahtela, T.3
  • 41
    • 84870294418 scopus 로고    scopus 로고
    • Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant
    • S.Rautava, E.Kainonen, S.Salminen, et al. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130:1355–1360.
    • (2012) J Allergy Clin Immunol , vol.130 , pp. 1355-1360
    • Rautava, S.1    Kainonen, E.2    Salminen, S.3
  • 42
    • 53049095486 scopus 로고    scopus 로고
    • A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial
    • K.Wickens, P.N.Black, T.V.Stanley, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2008;122:788–794.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 788-794
    • Wickens, K.1    Black, P.N.2    Stanley, T.V.3
  • 43
    • 84904620750 scopus 로고    scopus 로고
    • Th2-like chemokine levels are increased in allergic children and influenced by maternal immunity during pregnancy
    • M.S.Abelius, E.Lempinen, K.Lindblad, et al. Th2-like chemokine levels are increased in allergic children and influenced by maternal immunity during pregnancy. Pediatr Allergy Immunol. 2014;25:387–393.
    • (2014) Pediatr Allergy Immunol , vol.25 , pp. 387-393
    • Abelius, M.S.1    Lempinen, E.2    Lindblad, K.3
  • 44
    • 84875496238 scopus 로고    scopus 로고
    • Pre- and post-natal Lactobacillus reuteri supplementation decreases allergen responsiveness in infancy
    • A.Forsberg, T.R.Abrahamsson, B.Björkstén, et al. Pre- and post-natal Lactobacillus reuteri supplementation decreases allergen responsiveness in infancy. Clin Exp Allergy. 2013;43:434–442.
    • (2013) Clin Exp Allergy , vol.43 , pp. 434-442
    • Forsberg, A.1    Abrahamsson, T.R.2    Björkstén, B.3
  • 45
    • 84978024396 scopus 로고    scopus 로고
    • Pre- and postnatal administration of Lactobacillus reuteri decreases TLR2 responses in infants
    • A.Forsberg, T.R.Abrahamsson, B.Björkstén, et al. Pre- and postnatal administration of Lactobacillus reuteri decreases TLR2 responses in infants. Clin Transl Allergy. 2014;4:21.
    • (2014) Clin Transl Allergy , vol.4 , pp. 21
    • Forsberg, A.1    Abrahamsson, T.R.2    Björkstén, B.3
  • 46
    • 79952021189 scopus 로고    scopus 로고
    • Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial
    • R.J.Boyle, I.H.Ismail, S.Kivivuori, et al. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy. 2011;66:509–516.
    • (2011) Allergy , vol.66 , pp. 509-516
    • Boyle, R.J.1    Ismail, I.H.2    Kivivuori, S.3
  • 47
    • 84938058119 scopus 로고    scopus 로고
    • Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial
    • M.R.Simpson, C.K.Dotterud, O.Storro, et al. Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial. BMC Dermatol. 2015;15:13.
    • (2015) BMC Dermatol , vol.15 , pp. 13
    • Simpson, M.R.1    Dotterud, C.K.2    Storro, O.3
  • 48
    • 0038730917 scopus 로고    scopus 로고
    • Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial
    • M.Kalliomäki, S.Salminen, T.Poussa, et al. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet. 2003;361:1869–1871.
    • (2003) Lancet , vol.361 , pp. 1869-1871
    • Kalliomäki, M.1    Salminen, S.2    Poussa, T.3
  • 49
    • 34047116237 scopus 로고    scopus 로고
    • Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial
    • M.Kalliomäki, S.Salminen, T.Poussa, et al. Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial. J Allergy Clin Immunol. 2007;119:1019–1021.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1019-1021
    • Kalliomäki, M.1    Salminen, S.2    Poussa, T.3
  • 50
    • 40949124307 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation
    • M.V.Kopp, I.Hennemuth, A.Heinzmann, et al. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation. Pediatrics. 2008;121:e850–6.
    • (2008) Pediatrics , vol.121 , pp. e850-e856
    • Kopp, M.V.1    Hennemuth, I.2    Heinzmann, A.3
  • 51
    • 59449087653 scopus 로고    scopus 로고
    • Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort
    • M.Kuitunen, K.Kukkonen, K.Juntunen-Backman, et al. Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort. J Allergy Clin Immunol. 2009;123:335–341.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 335-341
    • Kuitunen, M.1    Kukkonen, K.2    Juntunen-Backman, K.3
  • 52
    • 84883159572 scopus 로고    scopus 로고
    • No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy
    • T.R.Abrahamsson, T.Jakobsson, B.Björkstén, et al. No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy. Pediatr Allergy Immunol. 2013;24:556–561.
    • (2013) Pediatr Allergy Immunol , vol.24 , pp. 556-561
    • Abrahamsson, T.R.1    Jakobsson, T.2    Björkstén, B.3
  • 53
    • 84862580765 scopus 로고    scopus 로고
    • A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years
    • K.Wickens, P.Black, T.V.Stanley, et al. A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy. 2012;42:1071–1079.
    • (2012) Clin Exp Allergy , vol.42 , pp. 1071-1079
    • Wickens, K.1    Black, P.2    Stanley, T.V.3
  • 54
    • 84882793349 scopus 로고    scopus 로고
    • Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?
    • K.Wickens, T.V.Stanley, E.A.Mitchell, et al. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization? Clin Exp Allergy. 2013;43:1048–1057.
    • (2013) Clin Exp Allergy , vol.43 , pp. 1048-1057
    • Wickens, K.1    Stanley, T.V.2    Mitchell, E.A.3
  • 55
    • 47649113201 scopus 로고    scopus 로고
    • Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study
    • A.Huurre, K.Laitinen, S.Rautava, et al. Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study. Clin Exp Allergy. 2008;38:1342–1348.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1342-1348
    • Huurre, A.1    Laitinen, K.2    Rautava, S.3
  • 56
    • 68949207372 scopus 로고    scopus 로고
    • The effects of selected probiotic strains on the development of eczema (the PandA study)
    • L.Niers, R.Martin, G.Rijkers, et al. The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy. 2009;64:1349–1358.
    • (2009) Allergy , vol.64 , pp. 1349-1358
    • Niers, L.1    Martin, R.2    Rijkers, G.3
  • 57
    • 84932080268 scopus 로고    scopus 로고
    • Preventive effects of selected probiotic strains on the development of asthma and allergic rhinitis in childhood. The Panda study
    • D.M.Gorissen, N.B.Rutten, C.M.Oostermeijer, et al. Preventive effects of selected probiotic strains on the development of asthma and allergic rhinitis in childhood. The Panda study. Clin Exp Allergy. 2014;44:1431–1433.
    • (2014) Clin Exp Allergy , vol.44 , pp. 1431-1433
    • Gorissen, D.M.1    Rutten, N.B.2    Oostermeijer, C.M.3
  • 58
    • 77950235521 scopus 로고    scopus 로고
    • Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial
    • J.Y.Kim, J.H.Kwon, S.H.Ahn, et al. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immunol. 2010;21:e386–93.
    • (2010) Pediatr Allergy Immunol , vol.21 , pp. e386-e393
    • Kim, J.Y.1    Kwon, J.H.2    Ahn, S.H.3
  • 59
    • 84865544963 scopus 로고    scopus 로고
    • Prenatal and postnatal probiotics reduces maternal but not childhood allergic diseases: a randomized, double-blind, placebo-controlled trial
    • C.Y.Ou, H.C.Kuo, L.Wang, et al. Prenatal and postnatal probiotics reduces maternal but not childhood allergic diseases: a randomized, double-blind, placebo-controlled trial. Clin Exp Allergy. 2012;42:1386–1396.
    • (2012) Clin Exp Allergy , vol.42 , pp. 1386-1396
    • Ou, C.Y.1    Kuo, H.C.2    Wang, L.3
  • 60
    • 84907933001 scopus 로고    scopus 로고
    • Probiotics in the prevention of eczema: a randomised controlled trial
    • S.J.Allen, S.Jordan, M.Storey, et al. Probiotics in the prevention of eczema: a randomised controlled trial. Arch Dis Child. 2014;99:1014–1019.
    • (2014) Arch Dis Child , vol.99 , pp. 1014-1019
    • Allen, S.J.1    Jordan, S.2    Storey, M.3
  • 61
    • 33845931138 scopus 로고    scopus 로고
    • Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial
    • A.L.Taylor, J.A.Dunstan, S.L.Prescott. Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial. J Allergy Clin Immunol. 2007;119:184–191.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 184-191
    • Taylor, A.L.1    Dunstan, J.A.2    Prescott, S.L.3
  • 62
    • 84869122300 scopus 로고    scopus 로고
    • Early probiotic supplementation for allergy prevention: long-term outcomes
    • M.P.Jensen, S.Meldrum, A.L.Taylor, et al. Early probiotic supplementation for allergy prevention: long-term outcomes. J Allergy Clin Immunol. 2012;130:1209–11 e5.
    • (2012) J Allergy Clin Immunol , vol.130 , pp. 1209-11 e5
    • Jensen, M.P.1    Meldrum, S.2    Taylor, A.L.3
  • 63
    • 62449251219 scopus 로고    scopus 로고
    • Probiotic supplementation in the first 6 months of life in at risk Asian infants–effects on eczema and atopic sensitization at the age of 1 year
    • S.E.Soh, M.Aw, I.Gerez, et al. Probiotic supplementation in the first 6 months of life in at risk Asian infants–effects on eczema and atopic sensitization at the age of 1 year. Clin Exp Allergy. 2009;39:571–578.
    • (2009) Clin Exp Allergy , vol.39 , pp. 571-578
    • Soh, S.E.1    Aw, M.2    Gerez, I.3
  • 64
    • 84893095282 scopus 로고    scopus 로고
    • Supplementation with probiotics in the first 6 months of life did not protect against eczema and allergy in at-risk Asian infants: a 5-year follow-up
    • E.X.Loo, G.V.Llanora, Q.Lu, et al. Supplementation with probiotics in the first 6 months of life did not protect against eczema and allergy in at-risk Asian infants: a 5-year follow-up. Int Arch Allergy Immunol. 2014;163:25–28.
    • (2014) Int Arch Allergy Immunol , vol.163 , pp. 25-28
    • Loo, E.X.1    Llanora, G.V.2    Lu, Q.3
  • 66
    • 84883154738 scopus 로고    scopus 로고
    • Probiotics in primary prevention of allergic disease - follow-up at 8-9 years of age
    • C.E.West, M.-L.Hammarström, O.Hernell. Probiotics in primary prevention of allergic disease - follow-up at 8-9 years of age. Allergy. 2013;68:1015–1020.
    • (2013) Allergy , vol.68 , pp. 1015-1020
    • West, C.E.1    Hammarström, M.-L.2    Hernell, O.3
  • 67
    • 84975143943 scopus 로고    scopus 로고
    • Probiotics for allergy prevention
    • [Epub ahead of print]
    • C.E.West. Probiotics for allergy prevention. Benef Microbes. 2015 [Dec 21]; 1–10. [Epub ahead of print].
    • (2015) Benef Microbes , pp. 1-10
    • West, C.E.1
  • 68
    • 82155173521 scopus 로고    scopus 로고
    • A Th1/Th2-associated chemokine imbalance during infancy in children developing eczema, wheeze and sensitization
    • T.R.Abrahamsson, M.Sandberg Abelius, A.Forsberg, et al. A Th1/Th2-associated chemokine imbalance during infancy in children developing eczema, wheeze and sensitization. Clin Exp Allergy. 2011;41:1729–1739.
    • (2011) Clin Exp Allergy , vol.41 , pp. 1729-1739
    • Abrahamsson, T.R.1    Sandberg Abelius, M.2    Forsberg, A.3
  • 69
    • 80053906217 scopus 로고    scopus 로고
    • High cord blood levels of the T-helper 2-associated chemokines CCL17 and CCL22 precede allergy development during the first 6 years of life
    • M.S.Abelius, J.Ernerudh, G.Berg, et al. High cord blood levels of the T-helper 2-associated chemokines CCL17 and CCL22 precede allergy development during the first 6 years of life. Pediatr Res. 2011;70:495–500.
    • (2011) Pediatr Res , vol.70 , pp. 495-500
    • Abelius, M.S.1    Ernerudh, J.2    Berg, G.3
  • 70
    • 80855139794 scopus 로고    scopus 로고
    • Slow salivary secretory IgA maturation may relate to low microbial pressure and allergic symptoms in sensitized children
    • M.Fagerås, S.Tomicic, T.Voor, et al. Slow salivary secretory IgA maturation may relate to low microbial pressure and allergic symptoms in sensitized children. Pediatr Res. 2011;70:572–577.
    • (2011) Pediatr Res , vol.70 , pp. 572-577
    • Fagerås, M.1    Tomicic, S.2    Voor, T.3
  • 71
    • 84939645206 scopus 로고    scopus 로고
    • Gut microbiome and innate immune response patterns in IgE-associated eczema
    • C.E.West, P.Rydén, D.Lundin, et al. Gut microbiome and innate immune response patterns in IgE-associated eczema. Clin Exp Allergy. 2015;45:1419–1429.• In this study, reduced relative abundance of tolerance-associated gut bacteria, e.g. Proteobacteria and Ruminoccoccaceae, was seen in infants developing IgE-associated eczema compared with infants that remained nonallergic. The reduction of these gut bacteria was associated with exaggerated innate immune responses and higher production of inflammatory biomarkers.
    • (2015) Clin Exp Allergy , vol.45 , pp. 1419-1429
    • West, C.E.1    Rydén, P.2    Lundin, D.3
  • 73
    • 84901238189 scopus 로고    scopus 로고
    • Low gut microbiota diversity in early infancy precedes asthma at school age
    • T.R.Abrahamsson, H.E.Jakobsson, A.F.Andersson, et al. Low gut microbiota diversity in early infancy precedes asthma at school age. Clin Exp Allergy. 2014;44:842–850.• In this study, children with asthma at school age had a lower diversity of the total microbiota at 1 week and 1 month of age compared with nonasthmatic children. A similar association was not found for allergic rhinoconjunctivitis, although both these findings should be confirmed in larger studies. The authors speculated that a less diverse microbial stimulation could have resulted in a reduced mucosal barrier function, leading to increased airway viral infection susceptibility, amplification of Th2 responses, and subsequent asthma development.
    • (2014) Clin Exp Allergy , vol.44 , pp. 842-850
    • Abrahamsson, T.R.1    Jakobsson, H.E.2    Andersson, A.F.3
  • 74
    • 84942874856 scopus 로고    scopus 로고
    • Early infancy microbial and metabolic alterations affect risk of childhood asthma
    • M.C.Arrieta, L.T.Stiemsma, P.A.Dimitriu, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med. 2015;7:307ra152.•• In this study, the gut microbiome of 319 infants was assessed. Infants at risk of asthma demonstrated transient gut microbial dysbiosis in the first 100 days of life with lower relative abundance of Lachnospira, Veillonella, Faecalibacterium, and Rothia. This occurred in conjunction with reduced acetate levels in stool and dysregulation of enterohepatic metabolites. When germ-free mice were inoculated with these four taxa, reduced airway inflammation in their adult offspring was seen, suggesting a role of these taxa in preventing asthma. Neutrophilic but not eosinophilic infiltration was attenuated by the inoculation, possibly questioning the relevance for human pediatric asthma, which is typically eosinophilia-dominated.
    • (2015) Sci Transl Med , vol.7 , pp. 307ra152
    • Arrieta, M.C.1    Stiemsma, L.T.2    Dimitriu, P.A.3
  • 75
    • 84942581015 scopus 로고    scopus 로고
    • Does maternal perinatal probiotic supplementation alter the intestinal microbiota of mother and child? A randomized controlled trial
    • C.K.Dotterud, E.Avershina, M.Sekelja, et al. Does maternal perinatal probiotic supplementation alter the intestinal microbiota of mother and child? A randomized controlled trial. J Pediatr Gastroenterol Nutr. 2015;61:200–207.• Intake of a probiotic combination in pregnancy and during breastfeeding reduced the incidence of eczema in childhood, and in this study, it was shown that only one of the administered strains, L. rhamnosus GG, increased in the infant’s stool during the intervention. This suggests that specific probiotic strains are more apt to transfer from mother to child.
    • (2015) J Pediatr Gastroenterol Nutr , vol.61 , pp. 200-207
    • Dotterud, C.K.1    Avershina, E.2    Sekelja, M.3
  • 76
    • 0031041742 scopus 로고    scopus 로고
    • Probiotics: a novel approach in the management of food allergy
    • H.Majamaa, E.Isolauri. Probiotics: a novel approach in the management of food allergy. J Allergy Clin Immunol. 1997;99:179–185.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 179-185
    • Majamaa, H.1    Isolauri, E.2
  • 77
    • 0033677619 scopus 로고    scopus 로고
    • Probiotics in the management of atopic eczema
    • E.Isolauri, T.Arvola, Y.Sutas, et al. Probiotics in the management of atopic eczema. Clin Exp Allergy. 2000;30:1604–1610.
    • (2000) Clin Exp Allergy , vol.30 , pp. 1604-1610
    • Isolauri, E.1    Arvola, T.2    Sutas, Y.3
  • 79
    • 84905085549 scopus 로고    scopus 로고
    • Effects of probiotics for the treatment of atopic dermatitis: a meta-analysis of randomized controlled trials
    • S.O.Kim, Y.M.Ah, Y.M.Yu, et al. Effects of probiotics for the treatment of atopic dermatitis: a meta-analysis of randomized controlled trials. Ann Allergy Asthma Immunol. 2014;113:217–226.
    • (2014) Ann Allergy Asthma Immunol , vol.113 , pp. 217-226
    • Kim, S.O.1    Ah, Y.M.2    Yu, Y.M.3
  • 81
    • 84935071781 scopus 로고    scopus 로고
    • Regulation of T cell immunity in atopic dermatitis by microbes: the Yin and Yang of cutaneous inflammation
    • T.Biedermann, Y.Skabytska, S.Kaesler, et al. Regulation of T cell immunity in atopic dermatitis by microbes: the Yin and Yang of cutaneous inflammation. Front Immunol. 2015;6:353.
    • (2015) Front Immunol , vol.6 , pp. 353
    • Biedermann, T.1    Skabytska, Y.2    Kaesler, S.3
  • 82
    • 44749087940 scopus 로고    scopus 로고
    • The acquisition of tolerance toward cow’s milk through probiotic supplementation: a randomized, controlled trial
    • J.Hol, E.H.Van Leer, B.E.Elink Schuurman, et al. The acquisition of tolerance toward cow’s milk through probiotic supplementation: a randomized, controlled trial. J Allergy Clin Immunol. 2008;12:1448–1454.
    • (2008) J Allergy Clin Immunol , vol.12 , pp. 1448-1454
    • Hol, J.1    Van Leer, E.H.2    Elink Schuurman, B.E.3
  • 83
    • 84856491460 scopus 로고    scopus 로고
    • Effect of Lactobacillus GG on tolerance acquisition in infants with cow’s milk allergy: a randomized trial
    • R.Berni Canani, R.Nocerino, G.Terrin, et al. Effect of Lactobacillus GG on tolerance acquisition in infants with cow’s milk allergy: a randomized trial. J Allergy Clin Immunol. 2012;129:580-2, 2 e1-5.
    • (2012) J Allergy Clin Immunol , vol.129
    • Berni Canani, R.1    Nocerino, R.2    Terrin, G.3
  • 84
  • 85
    • 84924618612 scopus 로고    scopus 로고
    • Administration of a probiotic with peanut oral immunotherapy: A randomized trial
    • M.L.Tang, A.L.Ponsonby, F.Orsini, et al. Administration of a probiotic with peanut oral immunotherapy: A randomized trial. J Allergy Clin Immunol. 2015;135:737–44 e8.• Compared with placebo, the combination of peanut oral immunotherapy and intake of a probiotic L. rhamnosus strain induced desensitization at a much higher rate. This interesting observation should be evaluated using a three-arm design to examine if the benefit of the combined peanut and probiotic therapy is superior to peanut oral immunotherapy alone.
    • (2015) J Allergy Clin Immunol , vol.135 , pp. 737-44 e8
    • Tang, M.L.1    Ponsonby, A.L.2    Orsini, F.3
  • 86
    • 84930473147 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of probiotics for the treatment of allergic rhinitis
    • A.E.Zajac, A.S.Adams, J.H.Turner. A systematic review and meta-analysis of probiotics for the treatment of allergic rhinitis. Int Forum Allergy Rhinol. 2015;5:524–532.
    • (2015) Int Forum Allergy Rhinol , vol.5 , pp. 524-532
    • Zajac, A.E.1    Adams, A.S.2    Turner, J.H.3
  • 87
    • 57449108914 scopus 로고    scopus 로고
    • Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials
    • H.Vliagoftis, V.D.Kouranos, G.I.Betsi, et al. Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials. Ann Allergy Asthma Immunol. 2008;101:570–579.
    • (2008) Ann Allergy Asthma Immunol , vol.101 , pp. 570-579
    • Vliagoftis, H.1    Kouranos, V.D.2    Betsi, G.I.3
  • 88
    • 84943455801 scopus 로고    scopus 로고
    • Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials
    • C.A.Cuello-Garcia, J.L.Brozek, A.Fiocchi, et al. Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol. 2015;136:952–961.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 952-961
    • Cuello-Garcia, C.A.1    Brozek, J.L.2    Fiocchi, A.3
  • 89
    • 84945466289 scopus 로고    scopus 로고
    • Probiotics for prevention of atopic diseases in infants: systematic review and meta-analysis
    • G.Zuccotti, F.Meneghin, A.Aceti, et al. Probiotics for prevention of atopic diseases in infants: systematic review and meta-analysis. Allergy. 2015;70:1356–1371.
    • (2015) Allergy , vol.70 , pp. 1356-1371
    • Zuccotti, G.1    Meneghin, F.2    Aceti, A.3
  • 90
    • 84872257018 scopus 로고    scopus 로고
    • Clinical use of probiotics in pediatric allergy (CUPPA): A world allergy organization position paper
    • A.Fiocchi, W.Burks, S.L.Bahna, et al. Clinical use of probiotics in pediatric allergy (CUPPA): A world allergy organization position paper. World Allergy Organ J. 2012;5:148–167.
    • (2012) World Allergy Organ J , vol.5 , pp. 148-167
    • Fiocchi, A.1    Burks, W.2    Bahna, S.L.3
  • 91
    • 84904044411 scopus 로고    scopus 로고
    • EAACI food allergy and anaphylaxis guidelines: managing patients with food allergy in the community
    • A.Muraro, I.Agache, A.Clark, et al. EAACI food allergy and anaphylaxis guidelines: managing patients with food allergy in the community. Allergy. 2014;69:1046–1057.
    • (2014) Allergy , vol.69 , pp. 1046-1057
    • Muraro, A.1    Agache, I.2    Clark, A.3
  • 92
    • 84890081710 scopus 로고    scopus 로고
    • Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis
    • M.B.Azad, J.G.Coneys, A.L.Kozyrskyj, et al. Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis. Bmj. 2013;347:f6471.
    • (2013) Bmj , vol.347 , pp. f6471
    • Azad, M.B.1    Coneys, J.G.2    Kozyrskyj, A.L.3
  • 93
    • 84891743361 scopus 로고    scopus 로고
    • Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases
    • R.J.Bertelsen, A.L.Brantsaeter, M.C.Magnus, et al. Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases. J Allergy Clin Immunol. 2014;133:165-71 e1-8.•• In this large population-based Norwegian cohort study MoBa, the reported intake of probiotic milk products in pregnancy and infancy was associated with a reduced incidence of eczema and rhinocinjunctivitis, but not asthma, at 3 years of age.
    • (2014) J Allergy Clin Immunol , vol.133
    • Bertelsen, R.J.1    Brantsaeter, A.L.2    Magnus, M.C.3
  • 94
    • 70349106871 scopus 로고    scopus 로고
    • Probiotic lactobacilli in breast milk and infant stool in relation to oral intake during the first year of life
    • T.R.Abrahamsson, G.Sinkiewicz, T.Jakobsson, et al. Probiotic lactobacilli in breast milk and infant stool in relation to oral intake during the first year of life. J Pediatr Gastroenterol Nutr. 2009;49:349–354.
    • (2009) J Pediatr Gastroenterol Nutr , vol.49 , pp. 349-354
    • Abrahamsson, T.R.1    Sinkiewicz, G.2    Jakobsson, T.3
  • 95
    • 34548303933 scopus 로고    scopus 로고
    • Post-cesarean surgical site infections according to CDC standards: rates and risk factors. A prospective cohort study
    • H.K.Opoien, A.Valbo, A.Grinde-Andersen, et al. Post-cesarean surgical site infections according to CDC standards: rates and risk factors. A prospective cohort study. Acta Obstet Gynecol Scand. 2007;86:1097–1102.
    • (2007) Acta Obstet Gynecol Scand , vol.86 , pp. 1097-1102
    • Opoien, H.K.1    Valbo, A.2    Grinde-Andersen, A.3
  • 96
    • 84938593795 scopus 로고    scopus 로고
    • World allergy organization-mcmaster university guidelines for allergic disease prevention (GLAD-P): probiotics
    • A.Fiocchi, R.Pawankar, C.Cuello-Garcia, et al. World allergy organization-mcmaster university guidelines for allergic disease prevention (GLAD-P): probiotics. World Allergy Organ J. 2015;8:4.
    • (2015) World Allergy Organ J , vol.8 , pp. 4
    • Fiocchi, A.1    Pawankar, R.2    Cuello-Garcia, C.3
  • 97
    • 79951951792 scopus 로고    scopus 로고
    • GRADE guidelines: 2. Framing the question and deciding on important outcomes
    • G.H.Guyatt, A.D.Oxman, R.Kunz, et al. GRADE guidelines: 2. Framing the question and deciding on important outcomes. J Clin Epidemiol. 2011;64:395–400.
    • (2011) J Clin Epidemiol , vol.64 , pp. 395-400
    • Guyatt, G.H.1    Oxman, A.D.2    Kunz, R.3
  • 99
    • 84899066468 scopus 로고    scopus 로고
    • Asthma: NHLBI workshop on the primary prevention of chronic lung diseases
    • D.J.Jackson, T.V.Hartert, F.D.Martinez, et al. Asthma: NHLBI workshop on the primary prevention of chronic lung diseases. Ann Am Thorac Soc. 2014;11 Suppl 3(Suppl 3):S139–45.
    • (2014) Ann Am Thorac Soc , vol.11 Suppl 3 , pp. S139-S145
    • Jackson, D.J.1    Hartert, T.V.2    Martinez, F.D.3


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