Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant

Journal of Allergy and Clinical Immunology

Volumn 130, Issue 6, 2012, Pages 1355-1360

  Rautava, Samuli ^a   Kainonen, Essi ^a   Salminen, Seppo ^b   Isolauri, Erika ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

breast feeding; Eczema; infant; probiotics

Indexed keywords

PLACEBO; PROBIOTIC AGENT;

ADULT; ALLERGIC DISEASE; ARTICLE; ATOPY; BIFIDOBACTERIUM LONGUM; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; ECZEMA; FEMALE; FOLLOW UP; HUMAN; LACTATION; LACTOBACILLUS RHAMNOSUS; PREGNANCY; PRICK TEST; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SKIN SENSITIZATION; UNSPECIFIED SIDE EFFECT;

ADULT; BREAST FEEDING; DIETARY SUPPLEMENTS; ECZEMA; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULIN E; INFANT, NEWBORN; MALE; MATERNAL EXPOSURE; PREGNANCY; PROBIOTICS; RISK; SKIN TESTS; YOUNG ADULT;

EID: 84870294418     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.09.003     Document Type: Article

References (37)

1. M. Kalliomäki, S. Salminen, H. Arvilommi, P. Kero, P. Koskinen, and E. Isolauri Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial Lancet 357 2001 1076 1079
2. T.R. Abrahamsson, T. Jakobsson, M.F. Böttcher, M. Fredrikson, M.C. Jenmalm, and B. Björkstén Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial J Allergy Clin Immunol 119 2007 1174 1180
3. K. Kukkonen, E. Savilahti, T. Haahtela, K. Juntunen-Backman, R. Korpela, and T. Poussa Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial J Allergy Clin Immunol 119 2007 192 198
4. K. Wickens, P.N. Black, T.V. Stanley, E. Mitchell, P. Fitzharris, and G.W. Tannock A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial J Allergy Clin Immunol 122 2008 788 794
5. L. Niers, R. Martín, G. Rijkers, F. Sengers, H. Timmerman, and N. van Uden The effects of selected probiotic strains on the development of eczema (the PandA study) Allergy 64 2009 1349 1358
6. C.K. Dotterud, O. Storro, R. Johnsen, and T. Oien Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial Br J Dermatol 163 2010 616 623
7. J.Y. Kim, J.H. Kwon, S.H. Ahn, S.I. Lee, Y.S. Han, and Y.O. Choi Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial Pediatr Allergy Immunol 21 2010 e386 e393
8. M.V. Kopp, I. Hennemuth, A. Heinzmann, and R. Urbanek Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation Pediatrics 121 2008 e850 e856
9. A.L. Taylor, J.A. Dunstan, and S.L. Prescott Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial J Allergy Clin Immunol 119 2007 184 191
10. S.E. Soh, M. Aw, I. Gerez, Y.S. Chong, M. Rauff, and Y.P. Ng Probiotic supplementation in the first 6 months of life in at risk Asian infants - effects on eczema and atopic sensitization at the age of 1 year Clin Exp Allergy 39 2009 571 578
11. R.J. Boyle, I.H. Ismail, S. Kivivuori, P.V. Licciardi, R.M. Robins-Browne, and L.J. Mah Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial Allergy 66 2011 509 516
12. S. Rautava, M. Kalliomäki, and E. Isolauri Probiotics during pregnancy and breast-feeding might confer immunomodulatory protection against atopic disease in the infant J Allergy Clin Immunol 109 2002 119 121
13. L.B. von Kobyletzki, C.G. Bornehag, M. Hasselgren, M. Larsson, C. Boman Lindström, and A. Svensson Eczema in early childhood is strongly associated with the development of asthma and rhinitis in a prospective cohort BMC Dermatol 12 2012 11
14. K. Laitinen, M. Kalliomäki, T. Poussa, H. Lagström, and E. Isolauri Evaluation of diet and growth in children with and without atopic eczema: follow-up study from birth to 4 years Br J Nutr 94 2005 565 574
15. J.M. Hanifin Atopic dermatitis in infants and children Pediatr Clin North Am 38 1991 763 789
16. E. Isolauri, and K. Turjanmaa Combined skin prick and patch testing enhances identification of food allergy in infants with atopic dermatitis J Allergy Clin Immunol 97 1996 9 15
17. C. Caffarelli, G. Cavagni, S. Giordano, S. Stapane, and C. Rossi Relationship between oral challenges with previously uningested egg and egg-specific IgE antibodies and skin prick tests in infants with food allergy J Allergy Clin Immunol 95 1995 1215 1220
18. H. Majamaa, P. Moisio, K. Holm, and K. Turjanmaa Wheat allergy: diagnostic accuracy of skin prick and patch tests and specific IgE Allergy 54 1999 851 856
19. E. Isolauri, T. Arvola, Y. Sütas, E. Moilanen, and S. Salminen Probiotics in the management of atopic eczema Clin Exp Allergy 30 2000 1604 1610
20. A.C. Ouwehand, E. Isolauri, P.J. Kirjavainen, S. Tölkkö, and S.J. Salminen The mucus binding of Bifidobacterium lactis Bb12 is enhanced in the presence of Lactobacillus GG and Lact. delbrueckii subsp. bulgaricus Lett Appl Microbiol 30 2000 10 13
21. M.H. Land, K. Rouster-Stevens, C.R. Woods, M.L. Cannon, J. Cnota, and A.K. Shetty Lactobacillus sepsis associated with probiotic therapy Pediatrics 115 2005 178 181
22. A. Ohishi, S. Takahashi, Y. Ito, Y. Ohishi, K. Tsukamoto, and Y. Nanba Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele J Pediatr 156 2010 679 681
23. R. Luoto, E. Isolauri, and L. Lehtonen Safety of Lactobacillus GG probiotic in infants with very low birth weight: twelve years of experience Clin Infect Dis 50 2010 1327 1328
24. P. Manzoni, G. Lista, E. Gallo, P. Marangione, C. Priolo, and P. Fontana Routine Lactobacillus rhamnosus GG administration in VLBW infants: a retrospective, 6-year cohort study Early Hum Dev 87 Suppl 1 2011 S35 S38
25. S. Rautava, M. Kalliomäki, and E. Isolauri New therapeutic strategy for combating the increasing burden of allergic disease: probiotics - a Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota (NAMI) Research Group report J Allergy Clin Immunol 116 2005 31 37
26. C. Roduit, J. Wohlgensinger, R. Frei, S. Bitter, C. Bieli, and S. Loeliger Prenatal animal contact and gene expression of innate immunity receptors at birth are associated with atopic dermatitis J Allergy Clin Immunol 127 2011 179 185
27. M.L. Conrad, R. Ferstl, R. Teich, S. Brand, N. Blumer, and A.O. Yildirim Maternal TLR signalling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78 J Exp Med 206 2009 2869 2877
28. J.E. Mold, J. Michaelsson, T.D. Burt, M.O. Muench, K.P. Beckerman, and M.P. Busch Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero Science 322 2008 1562 1565
29. S. Rautava, M.C. Collado, S. Salminen, and E. Isolauri Probiotics modulate host-microbe interaction in the placenta and fetal gut: a randomized, double-blind, placebo-controlled trial Neonatology 102 2012 178 184
30. V. Verhasselt, V. Milcent, J. Cazareth, A. Kanda, S. Fleury, and D. Dombrowicz Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma Nat Med 14 2008 170 175
31. 2 specifically attenuates IL-1β-induced inflammatory responses in the immature human intestine via an SMAD6- and ERK-dependent mechanism Neonatology 99 2011 192 201
32. S. Rautava, L. Lu, N.N. Nanthakumar, A. Dubert-Ferrandon, and W.A. Walker TGF-β2 induces maturation of immature human intestinal epithelial cells and inhibits inflammatory cytokine responses induced via the NF-κB pathway J Pediatr Gastroenterol Nutr 54 2012 630 638
33. H.J. Harmsen, A.C. Wildeboer-Veloo, G.C. Raangs, A.A. Wagendorp, N. Klijn, and J.G. Bindels Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods J Pediatr Gastroenterol Nutr 30 2000 61 67
34. M. Gueimonde, K. Laitinen, S. Salminen, and E. Isolauri Breast milk: a source of bifidobacteria for infant gut development and maturation? Neonatology 92 2007 64 66
35. A. Donnet-Hughes, P.F. Perez, J. Doré, M. Leclerc, F. Levenez, and J. Benyacoub Potential role of the intestinal microbiota of the mother in neonatal immune education Proc Nutr Soc 69 2010 407 415
36. T.R. Abrahamsson, G. Sinkiewicz, T. Jakobsson, M. Fredrikson, and B. Björkstén Probiotic lactobacilli in breast milk and infant stool in relation to oral intake during the first year of life J Pediatr Gastroenterol Nutr 49 2009 349 354
37. S. Rautava, R. Luoto, S. Salminen, and E. Isolauri Microbial contact during pregnancy, intestinal colonization and human disease Nat Rev Gastroenterol Hepatol 2012 [Epub ahead of print]