Comparative metabolism of honokiol in mouse, rat, dog, monkey, and human hepatocytes

Archives of Pharmacal Research

Volumn 39, Issue 4, 2016, Pages 516-530

  Jeong, Hyeon Uk ^a   Kim, Ju Hyun ^a   Kong, Tae Yeon ^a   Choi, Won Gu ^a   Lee, Hye Suk ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Comparative metabolism; Hepatocytes; Honokiol; Sulfotransferases; UDP glucuronosyltransferases

Indexed keywords

ALLYL COMPOUND; COMPLEMENTARY DNA; DRUG METABOLITE; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 1A9; HONOKIOL; HONOKIOL 2' GLUCURONIDE; HONOKIOL 4 GLUCURONIDE; UNCLASSIFIED DRUG; ARYL SULFOTRANSFERASE; BIPHENYL DERIVATIVE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; LIGNAN; SULFATE;

ANIMAL CELL; ARTICLE; DRUG HALF LIFE; DRUG METABOLISM; DRUG OXIDATION; GLUCURONIDATION; HEPATIC CLEARANCE; HEPATIC EXTRACTION RATIO; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRINSIC CLEARANCE; LIQUID CHROMATOGRAPHY; LIVER CELL; MASS SPECTROMETRY; METABOLIC STABILITY; NONHUMAN; SPECIES DIFFERENCE; SULFATION; ANIMAL; BIOTRANSFORMATION; CELL CULTURE; DOG; ENZYMOLOGY; HAPLORHINI; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; ARYLSULFOTRANSFERASE; BIOTRANSFORMATION; BIPHENYL COMPOUNDS; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; DOGS; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HAPLORHINI; HEPATOCYTES; HUMANS; LIGNANS; MICE; OXIDATION-REDUCTION; RATS; SPECIES SPECIFICITY; SULFURIC ACID ESTERS; TANDEM MASS SPECTROMETRY;

EID: 84961207992     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-016-0731-y     Document Type: Article

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