Identification of metabolites of honokiol in rat urine using 13C stable isotope labeling and liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Journal of Chromatography A

Volumn 1295, Issue , 2013, Pages 48-56

  Liu, Juan ^a   Tang, Minghai ^a   Lai, Huijun ^a,b   Dong, Yinfeng ^a,b   Xie, Caifeng ^a   Ye, Haoyu ^a   Ma, Liang ^a   Qiu, Neng ^a,b   Li, Yanfang ^b   Cai, Lulu ^a   Chen, Lijuan ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Honokiol; Metabolite; UPLC Q TOF MS MS; Urine

Indexed keywords

GLUCURONIDATION; HONOKIOL; INTRAVENOUS ADMINISTRATION; METABOLIC PATHWAYS; QUADRUPOLE TIME-OF-FLIGHT TANDEM MASS SPECTROMETRIES; STABLE-ISOTOPE LABELING; UPLC/Q-TOF-MS/MS; URINE;

ACETYLATION; AMINO ACIDS; BIOMOLECULES; BODY FLUIDS; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; RATS;

METABOLITES;

ACETIC ACID DERIVATIVE; AMINO ACID; CARBON 13; GLUCURONIDE; HONOKIOL; SULFATE; BIPHENYL DERIVATIVE; HERBACEOUS AGENT; LIGNAN;

ACCURACY; ACETYLATION; AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONJUGATION; CONTROLLED STUDY; GLUCURONIDATION; IN VIVO STUDY; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MALE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; REACTION TIME; RELIABILITY; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; SULFATION; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; ANIMAL; BIOTRANSFORMATION; CHEMISTRY; EVALUATION; MAGNOLIACEAE; METABOLISM; METHODOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; BIOTRANSFORMATION; BIPHENYL COMPOUNDS; CHROMATOGRAPHY, LIQUID; DRUGS, CHINESE HERBAL; ISOTOPE LABELING; LIGNANS; MAGNOLIA; MALE; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY;

EID: 84886777539     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.03.031     Document Type: Article

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