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Volumn 43, Issue 2, 2016, Pages 291-299

Improving therapy of chronic lymphocytic leukemia with chimeric antigen receptor T cells

Author keywords

CAR; CLL; Immunotherapy; Leukemia; T cell

Indexed keywords

CD134 ANTIGEN; CD137 ANTIGEN; CD19 ANTIGEN; CD2 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; INDUCIBLE T CELL COSTIMULATOR; TISAGENLECLEUCEL T; HYBRID PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84961116781     PISSN: 00937754     EISSN: 15328708     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2016.02.006     Document Type: Review
Times cited : (12)

References (124)
  • 1
    • 84902590334 scopus 로고    scopus 로고
    • Paving the road to MRD-guided treatment in CLL
    • S. Bottcher Paving the road to MRD-guided treatment in CLL Blood 123 24 2014 3683 3684
    • (2014) Blood , vol.123 , Issue.24 , pp. 3683-3684
    • Bottcher, S.1
  • 2
    • 84919469417 scopus 로고    scopus 로고
    • Managing high-risk CLL during transition to a new treatment era: Stem cell transplantation or novel agents?
    • P. Dreger, J. Schetelig, N. Andersen, and et al. Managing high-risk CLL during transition to a new treatment era: Stem cell transplantation or novel agents? Blood 124 26 2014 3841 3849
    • (2014) Blood , vol.124 , Issue.26 , pp. 3841-3849
    • Dreger, P.1    Schetelig, J.2    Andersen, N.3
  • 3
    • 84879748062 scopus 로고    scopus 로고
    • Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
    • J.C. Byrd, R.R. Furman, S.E. Coutre, and et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia N Engl J Med 369 1 2013 32 42
    • (2013) N Engl J Med , vol.369 , Issue.1 , pp. 32-42
    • Byrd, J.C.1    Furman, R.R.2    Coutre, S.E.3
  • 4
    • 84896692766 scopus 로고    scopus 로고
    • Idelalisib and rituximab in relapsed chronic lymphocytic leukemia
    • R.R. Furman, J.P. Sharman, S.E. Coutre, and et al. Idelalisib and rituximab in relapsed chronic lymphocytic leukemia N Engl J Med 370 11 2014 997 1007
    • (2014) N Engl J Med , vol.370 , Issue.11 , pp. 997-1007
    • Furman, R.R.1    Sharman, J.P.2    Coutre, S.E.3
  • 5
    • 70350511471 scopus 로고    scopus 로고
    • Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): Dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
    • T. Zenz, S. Habe, T. Denzel, and et al. Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): Dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial Blood 114 13 2009 2589 2597
    • (2009) Blood , vol.114 , Issue.13 , pp. 2589-2597
    • Zenz, T.1    Habe, S.2    Denzel, T.3
  • 6
    • 84897490051 scopus 로고    scopus 로고
    • How will B-cell-receptor-targeted therapies change future CLL therapy?
    • J.A. Jones, and J.C. Byrd How will B-cell-receptor-targeted therapies change future CLL therapy? Blood 123 10 2014 1455 1460
    • (2014) Blood , vol.123 , Issue.10 , pp. 1455-1460
    • Jones, J.A.1    Byrd, J.C.2
  • 7
    • 84993705076 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase inhibitors and their clinical potential in the treatment of B-cell malignancies: Focus on ibrutinib
    • A. Aalipour, and R.H. Advani Bruton's tyrosine kinase inhibitors and their clinical potential in the treatment of B-cell malignancies: Focus on ibrutinib Ther Adv Hematol 5 4 2014 121 133
    • (2014) Ther Adv Hematol , vol.5 , Issue.4 , pp. 121-133
    • Aalipour, A.1    Advani, R.H.2
  • 8
    • 79951513494 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for chronic lymphocytic leukemia: Lessons to be learned from minimal residual disease studies
    • S. Bottcher, M. Ritgen, and P. Dreger Allogeneic stem cell transplantation for chronic lymphocytic leukemia: Lessons to be learned from minimal residual disease studies Blood Rev 25 2 2011 91 96
    • (2011) Blood Rev , vol.25 , Issue.2 , pp. 91-96
    • Bottcher, S.1    Ritgen, M.2    Dreger, P.3
  • 9
    • 84919497794 scopus 로고    scopus 로고
    • Transplant for CLL: Still an option?
    • S.M. Jaglowski Transplant for CLL: Still an option? Blood 124 26 2014 3835 3836
    • (2014) Blood , vol.124 , Issue.26 , pp. 3835-3836
    • Jaglowski, S.M.1
  • 10
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • 95ra73
    • M. Kalos, B.L. Levine, D.L. Porter, and et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia Sci Transl Med 3 95 2011 95ra73
    • (2011) Sci Transl Med , vol.3 , Issue.95
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3
  • 11
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • D.L. Porter, B.L. Levine, M. Kalos, A. Bagg, and C.H. June Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia N Engl J Med 365 8 2011 725 733
    • (2011) N Engl J Med , vol.365 , Issue.8 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 12
    • 80455179612 scopus 로고    scopus 로고
    • Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
    • R.J. Brentjens, I. Riviere, J.H. Park, and et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias Blood 118 18 2011 4817 4828
    • (2011) Blood , vol.118 , Issue.18 , pp. 4817-4828
    • Brentjens, R.J.1    Riviere, I.2    Park, J.H.3
  • 13
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • J.N. Kochenderfer, M.E. Dudley, S.A. Feldman, and et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells Blood 119 12 2012 2709 2720
    • (2012) Blood , vol.119 , Issue.12 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3
  • 14
    • 78549278144 scopus 로고    scopus 로고
    • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
    • J.N. Kochenderfer, W.H. Wilson, J.E. Janik, and et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19 Blood 116 20 2010 4099 4102
    • (2010) Blood , vol.116 , Issue.20 , pp. 4099-4102
    • Kochenderfer, J.N.1    Wilson, W.H.2    Janik, J.E.3
  • 15
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • B. Savoldo, C.A. Ramos, E. Liu, and et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients J Clin Invest 121 5 2011 1822 1826
    • (2011) J Clin Invest , vol.121 , Issue.5 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3
  • 19
    • 84940881287 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
    • 303ra139
    • D.L. Porter, W.T. Hwang, N.V. Frey, and et al. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia Sci Transl Med 7 303 2015 303ra139
    • (2015) Sci Transl Med , vol.7 , Issue.303
    • Porter, D.L.1    Hwang, W.T.2    Frey, N.V.3
  • 20
    • 84908073316 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells for sustained remissions in leukemia
    • S.L. Maude, N. Frey, P.A. Shaw, and et al. Chimeric antigen receptor T cells for sustained remissions in leukemia N Engl J Med 371 16 2014 1507 1517
    • (2014) N Engl J Med , vol.371 , Issue.16 , pp. 1507-1517
    • Maude, S.L.1    Frey, N.2    Shaw, P.A.3
  • 21
    • 0031978008 scopus 로고    scopus 로고
    • Adoptive tumor immunity mediated by lymphocytes bearing modified antigen-specific receptors
    • T. Brocker, and K. Karjalainen Adoptive tumor immunity mediated by lymphocytes bearing modified antigen-specific receptors Adv Immunol 68 1998 257 269
    • (1998) Adv Immunol , vol.68 , pp. 257-269
    • Brocker, T.1    Karjalainen, K.2
  • 22
    • 0037264471 scopus 로고    scopus 로고
    • Targeting tumours with genetically enhanced T lymphocytes
    • M. Sadelain, I. Riviere, and R. Brentjens Targeting tumours with genetically enhanced T lymphocytes Nat Rev Cancer 3 1 2003 35 45
    • (2003) Nat Rev Cancer , vol.3 , Issue.1 , pp. 35-45
    • Sadelain, M.1    Riviere, I.2    Brentjens, R.3
  • 23
    • 0024834988 scopus 로고
    • Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity
    • G. Gross, T. Waks, and Z. Eshhar Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity Proc Natl Acad Sci USA 86 24 1989 10024 10028
    • (1989) Proc Natl Acad Sci USA , vol.86 , Issue.24 , pp. 10024-10028
    • Gross, G.1    Waks, T.2    Eshhar, Z.3
  • 24
    • 0038181188 scopus 로고    scopus 로고
    • Immuno-gene therapy of established prostate tumors using chimeric receptor-redirected human lymphocytes
    • J.H. Pinthus, T. Waks, K. Kaufman-Francis, and et al. Immuno-gene therapy of established prostate tumors using chimeric receptor-redirected human lymphocytes Cancer Res 63 10 2003 2470 2476
    • (2003) Cancer Res , vol.63 , Issue.10 , pp. 2470-2476
    • Pinthus, J.H.1    Waks, T.2    Kaufman-Francis, K.3
  • 25
    • 0034804368 scopus 로고    scopus 로고
    • Protein-protein interactions in hematology and phage display
    • B.P. Mullaney, and M.G. Pallavicini Protein-protein interactions in hematology and phage display Exp Hematol 29 10 2001 1136 1146
    • (2001) Exp Hematol , vol.29 , Issue.10 , pp. 1136-1146
    • Mullaney, B.P.1    Pallavicini, M.G.2
  • 26
    • 0034283741 scopus 로고    scopus 로고
    • Chimeric Fv-zeta or Fv-epsilon receptors are not sufficient to induce activation or cytokine production in peripheral T cells
    • T. Brocker Chimeric Fv-zeta or Fv-epsilon receptors are not sufficient to induce activation or cytokine production in peripheral T cells Blood 96 5 2000 1999 2001
    • (2000) Blood , vol.96 , Issue.5 , pp. 1999-2001
    • Brocker, T.1
  • 27
    • 0031573612 scopus 로고    scopus 로고
    • + T cells in the absence of exogenous feeder cells
    • + T cells in the absence of exogenous feeder cells J Immunol 159 12 1997 5921 5930
    • (1997) J Immunol , vol.159 , Issue.12 , pp. 5921-5930
    • Levine, B.L.1    Bernstein, W.B.2    Connors, M.3
  • 28
    • 0036171757 scopus 로고    scopus 로고
    • Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB
    • M.V. Maus, A.K. Thomas, D.G. Leonard, and et al. Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB Nat Biotechnol 20 2 2002 143 148
    • (2002) Nat Biotechnol , vol.20 , Issue.2 , pp. 143-148
    • Maus, M.V.1    Thomas, A.K.2    Leonard, D.G.3
  • 29
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
    • S.A. Grupp, M. Kalos, D. Barrett, and et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia N Engl J Med 368 16 2013 1509 1518
    • (2013) N Engl J Med , vol.368 , Issue.16 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3
  • 30
    • 78049518331 scopus 로고    scopus 로고
    • The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells
    • 55ra78
    • C.M. Paulos, C. Carpenito, G. Plesa, and et al. The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells Sci Transl Med 2 55 2010 55ra78
    • (2010) Sci Transl Med , vol.2 , Issue.55
    • Paulos, C.M.1    Carpenito, C.2    Plesa, G.3
  • 31
    • 84905996839 scopus 로고    scopus 로고
    • ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
    • S. Guedan, X. Chen, A. Madar, and et al. ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells Blood 124 7 2014 1070 1080
    • (2014) Blood , vol.124 , Issue.7 , pp. 1070-1080
    • Guedan, S.1    Chen, X.2    Madar, A.3
  • 32
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • A.D. Miller, and G.J. Rosman Improved retroviral vectors for gene transfer and expression Biotechniques 7 9 1989 980 982
    • (1989) Biotechniques , vol.7 , Issue.9 , pp. 980-982
    • Miller, A.D.1    Rosman, G.J.2
  • 33
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • L. Naldini, U. Blomer, P. Gallay, and et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector Science 272 5259 1996 263 267
    • (1996) Science , vol.272 , Issue.5259 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3
  • 34
    • 78549253550 scopus 로고    scopus 로고
    • Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor
    • Y. Zhao, E. Moon, C. Carpenito, and et al. Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor Cancer Res 70 22 2010 9053 9061
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9053-9061
    • Zhao, Y.1    Moon, E.2    Carpenito, C.3
  • 35
    • 84940881287 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
    • Porter DL, Hwang W, Frey NV, et al. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia. Sci Transl Med. 2015;7(303):303ra139
    • (2015) Sci Transl Med , vol.7 , Issue.303 , pp. 303ra139
    • Porter, D.L.1    Hwang, W.2    Frey, N.V.3
  • 36
    • 84876478036 scopus 로고    scopus 로고
    • T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production
    • J.C. Riches, J.K. Davies, F. McClanahan, and et al. T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production Blood 121 9 2013 1612 1621
    • (2013) Blood , vol.121 , Issue.9 , pp. 1612-1621
    • Riches, J.C.1    Davies, J.K.2    McClanahan, F.3
  • 40
    • 0036076114 scopus 로고    scopus 로고
    • T cell homeostatic proliferation elicits effective antitumor autoimmunity
    • W. Dummer, A.G. Niethammer, R. Baccala, and et al. T cell homeostatic proliferation elicits effective antitumor autoimmunity J Clin Invest 110 2 2002 185 192
    • (2002) J Clin Invest , vol.110 , Issue.2 , pp. 185-192
    • Dummer, W.1    Niethammer, A.G.2    Baccala, R.3
  • 41
    • 80053997259 scopus 로고    scopus 로고
    • A human memory T cell subset with stem cell-like properties
    • L. Gattinoni, E. Lugli, Y. Ji, and et al. A human memory T cell subset with stem cell-like properties Nat Med 17 10 2011 1290 1297
    • (2011) Nat Med , vol.17 , Issue.10 , pp. 1290-1297
    • Gattinoni, L.1    Lugli, E.2    Ji, Y.3
  • 44
    • 84873395620 scopus 로고    scopus 로고
    • Superior T memory stem cell persistence supports long-lived T cell memory
    • E. Lugli, M.H. Dominguez, L. Gattinoni, and et al. Superior T memory stem cell persistence supports long-lived T cell memory J Clin Invest 123 2 2013 594 599
    • (2013) J Clin Invest , vol.123 , Issue.2 , pp. 594-599
    • Lugli, E.1    Dominguez, M.H.2    Gattinoni, L.3
  • 45
    • 84892536761 scopus 로고    scopus 로고
    • Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids
    • R. Ramesh, L. Kozhaya, K. McKevitt, and et al. Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids J Exp Med 211 1 2014 89 104
    • (2014) J Exp Med , vol.211 , Issue.1 , pp. 89-104
    • Ramesh, R.1    Kozhaya, L.2    McKevitt, K.3
  • 46
    • 84872498982 scopus 로고    scopus 로고
    • Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
    • S. Phuphanich, C.J. Wheeler, J.D. Rudnick, and et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma Cancer Immunol Immunother 62 1 2013 125 135
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.1 , pp. 125-135
    • Phuphanich, S.1    Wheeler, C.J.2    Rudnick, J.D.3
  • 47
    • 84861164043 scopus 로고    scopus 로고
    • Sipuleucel-T for the treatment of advanced prostate cancer
    • M.W. Frohlich Sipuleucel-T for the treatment of advanced prostate cancer Semin Oncol 39 3 2012 245 252
    • (2012) Semin Oncol , vol.39 , Issue.3 , pp. 245-252
    • Frohlich, M.W.1
  • 48
    • 67649671865 scopus 로고    scopus 로고
    • DCVax-Brain and DC vaccines in the treatment of GBM
    • C.J. Wheeler, and K.L. Black DCVax-Brain and DC vaccines in the treatment of GBM Expert Opin Investig Drugs 18 4 2009 509 519
    • (2009) Expert Opin Investig Drugs , vol.18 , Issue.4 , pp. 509-519
    • Wheeler, C.J.1    Black, K.L.2
  • 49
    • 70450162100 scopus 로고    scopus 로고
    • A changing world for DCvax: A PSMA loaded autologous dendritic cell vaccine for prostate cancer
    • M. Fishman A changing world for DCvax: A PSMA loaded autologous dendritic cell vaccine for prostate cancer Expert Opin Biol Ther 9 12 2009 1565 1575
    • (2009) Expert Opin Biol Ther , vol.9 , Issue.12 , pp. 1565-1575
    • Fishman, M.1
  • 51
    • 0034121654 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy
    • L. Fong, and E.G. Engleman Dendritic cells in cancer immunotherapy Annu Rev Immunol 18 2000 245 273
    • (2000) Annu Rev Immunol , vol.18 , pp. 245-273
    • Fong, L.1    Engleman, E.G.2
  • 52
    • 0034918104 scopus 로고    scopus 로고
    • Dendritic cells: On the move from bench to bedside
    • F.O. Nestle, J. Banchereau, and D. Hart Dendritic cells: On the move from bench to bedside Nat Med 7 7 2001 761 765
    • (2001) Nat Med , vol.7 , Issue.7 , pp. 761-765
    • Nestle, F.O.1    Banchereau, J.2    Hart, D.3
  • 53
    • 0029902054 scopus 로고    scopus 로고
    • T cells from patients with Hodgkin's disease have a defective T-cell receptor zeta chain expression that is reversible by T-cell stimulation with CD3 and CD28
    • C. Renner, S. Ohnesorge, G. Held, and et al. T cells from patients with Hodgkin's disease have a defective T-cell receptor zeta chain expression that is reversible by T-cell stimulation with CD3 and CD28 Blood 88 1 1996 236 241
    • (1996) Blood , vol.88 , Issue.1 , pp. 236-241
    • Renner, C.1    Ohnesorge, S.2    Held, G.3
  • 54
    • 0035874949 scopus 로고    scopus 로고
    • +) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • +) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer Cancer Res 61 12 2001 4766 4772
    • (2001) Cancer Res , vol.61 , Issue.12 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3
  • 55
    • 13544256621 scopus 로고    scopus 로고
    • In vitro engagement of CD3 and CD28 corrects T cell defects in chronic lymphocytic leukemia
    • M. Bonyhadi, M. Frohlich, A. Rasmussen, and et al. In vitro engagement of CD3 and CD28 corrects T cell defects in chronic lymphocytic leukemia J Immunol 174 4 2005 2366 2375
    • (2005) J Immunol , vol.174 , Issue.4 , pp. 2366-2375
    • Bonyhadi, M.1    Frohlich, M.2    Rasmussen, A.3
  • 56
    • 18944364610 scopus 로고    scopus 로고
    • Effect of CD3/CD28 bead-activated and expanded T cells on leukemic B cells in chronic lymphocytic leukemia
    • P. Patten, S. Devereux, A. Buggins, M. Bonyhadi, M. Frohlich, and R.J. Berenson Effect of CD3/CD28 bead-activated and expanded T cells on leukemic B cells in chronic lymphocytic leukemia J Immunol 174 11 2005 6562 6563
    • (2005) J Immunol , vol.174 , Issue.11 , pp. 6562-6563
    • Patten, P.1    Devereux, S.2    Buggins, A.3    Bonyhadi, M.4    Frohlich, M.5    Berenson, R.J.6
  • 57
    • 0038587735 scopus 로고    scopus 로고
    • Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells
    • M. Oelke, M.V. Maus, D. Didiano, C.H. June, A. Mackensen, and J.P. Schneck Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells Nat Med 9 5 2003 619 624
    • (2003) Nat Med , vol.9 , Issue.5 , pp. 619-624
    • Oelke, M.1    Maus, M.V.2    Didiano, D.3    June, C.H.4    MacKensen, A.5    Schneck, J.P.6
  • 58
    • 34247212403 scopus 로고    scopus 로고
    • Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules
    • M.M. Suhoski, T.N. Golovina, N.A. Aqui, and et al. Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules Mol Ther 15 5 2007 981 988
    • (2007) Mol Ther , vol.15 , Issue.5 , pp. 981-988
    • Suhoski, M.M.1    Golovina, T.N.2    Aqui, N.A.3
  • 59
    • 0035989039 scopus 로고    scopus 로고
    • A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy
    • S.G. Deeks, B. Wagner, P.A. Anton, and et al. A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy Mol Ther 5 6 2002 788 797
    • (2002) Mol Ther , vol.5 , Issue.6 , pp. 788-797
    • Deeks, S.G.1    Wagner, B.2    Anton, P.A.3
  • 60
    • 33750699642 scopus 로고    scopus 로고
    • A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
    • M.H. Kershaw, J.A. Westwood, L.L. Parker, and et al. A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer Clin Cancer Res 12 20 Pt 1 2006 6106 6115
    • (2006) Clin Cancer Res , vol.12 , Issue.20 PART 1 , pp. 6106-6115
    • Kershaw, M.H.1    Westwood, J.A.2    Parker, L.L.3
  • 61
    • 33947265424 scopus 로고    scopus 로고
    • Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma
    • J.R. Park, D.L. Digiusto, M. Slovak, and et al. Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma Mol Ther 15 4 2007 825 833
    • (2007) Mol Ther , vol.15 , Issue.4 , pp. 825-833
    • Park, J.R.1    Digiusto, D.L.2    Slovak, M.3
  • 62
    • 79953814653 scopus 로고    scopus 로고
    • Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL
    • P. Christopoulos, D. Pfeifer, K. Bartholome, and et al. Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL Blood 117 14 2011 3836 3846
    • (2011) Blood , vol.117 , Issue.14 , pp. 3836-3846
    • Christopoulos, P.1    Pfeifer, D.2    Bartholome, K.3
  • 63
    • 0029051433 scopus 로고
    • Expression of CD27 and its ligand, CD70, on chronic lymphocytic leukemia B cells
    • E.A. Ranheim, M.J. Cantwell, and T.J. Kipps Expression of CD27 and its ligand, CD70, on chronic lymphocytic leukemia B cells Blood 85 12 1995 3556 3565
    • (1995) Blood , vol.85 , Issue.12 , pp. 3556-3565
    • Ranheim, E.A.1    Cantwell, M.J.2    Kipps, T.J.3
  • 64
    • 0027499535 scopus 로고
    • Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal
    • E.A. Ranheim, and T.J. Kipps Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal J Exp Med. 177 4 1993 925 935
    • (1993) J Exp Med. , vol.177 , Issue.4 , pp. 925-935
    • Ranheim, E.A.1    Kipps, T.J.2
  • 65
    • 78649777544 scopus 로고    scopus 로고
    • T-cell function in chronic lymphocytic leukaemia
    • J.C. Riches, A.G. Ramsay, and J.G. Gribben T-cell function in chronic lymphocytic leukaemia Semin Cancer Biol 20 6 2010 431 438
    • (2010) Semin Cancer Biol , vol.20 , Issue.6 , pp. 431-438
    • Riches, J.C.1    Ramsay, A.G.2    Gribben, J.G.3
  • 66
    • 0030989818 scopus 로고    scopus 로고
    • CD40 triggering of chronic lymphocytic leukemia B cells results in efficient alloantigen presentation and cytotoxic T lymphocyte induction by up-regulation of CD80 and CD86 costimulatory molecules
    • L.E. Van den Hove, S.W. Van Gool, P. Vandenberghe, and et al. CD40 triggering of chronic lymphocytic leukemia B cells results in efficient alloantigen presentation and cytotoxic T lymphocyte induction by up-regulation of CD80 and CD86 costimulatory molecules Leukemia 11 4 1997 572 580
    • (1997) Leukemia , vol.11 , Issue.4 , pp. 572-580
    • Van Den Hove, L.E.1    Van Gool, S.W.2    Vandenberghe, P.3
  • 67
    • 0028365149 scopus 로고
    • T lymphocyte T cell-B cell-activating molecule/CD40-L molecules induce normal B cells or chronic lymphocytic leukemia B cells to express CD80 (B7/BB-1) and enhance their costimulatory activity
    • M.J. Yellin, J. Sinning, L.R. Covey, and et al. T lymphocyte T cell-B cell-activating molecule/CD40-L molecules induce normal B cells or chronic lymphocytic leukemia B cells to express CD80 (B7/BB-1) and enhance their costimulatory activity J Immunol. 153 2 1994 666 674
    • (1994) J Immunol. , vol.153 , Issue.2 , pp. 666-674
    • Yellin, M.J.1    Sinning, J.2    Covey, L.R.3
  • 68
    • 84909981772 scopus 로고    scopus 로고
    • Multidimensional scaling analysis identifies pathological and prognostically relevant profiles of circulating T-cells in chronic lymphocytic leukemia
    • A. Rissiek, C. Schulze, U. Bacher, and et al. Multidimensional scaling analysis identifies pathological and prognostically relevant profiles of circulating T-cells in chronic lymphocytic leukemia Int J Cancer 135 10 2014 2370 2379
    • (2014) Int J Cancer , vol.135 , Issue.10 , pp. 2370-2379
    • Rissiek, A.1    Schulze, C.2    Bacher, U.3
  • 69
    • 79956275845 scopus 로고    scopus 로고
    • A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease
    • D. Bagnara, M.S. Kaufman, C. Calissano, and et al. A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease Blood 117 20 2011 5463 5472
    • (2011) Blood , vol.117 , Issue.20 , pp. 5463-5472
    • Bagnara, D.1    Kaufman, M.S.2    Calissano, C.3
  • 70
    • 70350734809 scopus 로고    scopus 로고
    • The microenvironment in mature B-cell malignancies: A target for new treatment strategies
    • J.A. Burger, P. Ghia, A. Rosenwald, and F. Caligaris-Cappio The microenvironment in mature B-cell malignancies: A target for new treatment strategies Blood 114 16 2009 3367 3375
    • (2009) Blood , vol.114 , Issue.16 , pp. 3367-3375
    • Burger, J.A.1    Ghia, P.2    Rosenwald, A.3    Caligaris-Cappio, F.4
  • 71
    • 84861348588 scopus 로고    scopus 로고
    • A shorter time to the first treatment may be predicted by the absolute number of regulatory T-cells in patients with Rai stage 0 chronic lymphocytic leukemia
    • G. D'Arena, F. D'Auria, V. Simeon, and et al. A shorter time to the first treatment may be predicted by the absolute number of regulatory T-cells in patients with Rai stage 0 chronic lymphocytic leukemia Am J Hematol 87 6 2012 628 631
    • (2012) Am J Hematol , vol.87 , Issue.6 , pp. 628-631
    • D'Arena, G.1    D'Auria, F.2    Simeon, V.3
  • 72
    • 79952100710 scopus 로고    scopus 로고
    • Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease
    • G. D'Arena, L. Laurenti, M.M. Minervini, and et al. Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease Leuk Res 35 3 2011 363 368
    • (2011) Leuk Res , vol.35 , Issue.3 , pp. 363-368
    • D'Arena, G.1    Laurenti, L.2    Minervini, M.M.3
  • 73
    • 84856577660 scopus 로고    scopus 로고
    • Circulating regulatory T cells in clinical monoclonal B-cell lymphocytosis
    • G. D'Arena, G. Rossi, M.M. Minervini, and et al. Circulating regulatory T cells in clinical monoclonal B-cell lymphocytosis Int J Immunopathol Pharmacol 24 4 2011 915 923
    • (2011) Int J Immunopathol Pharmacol , vol.24 , Issue.4 , pp. 915-923
    • D'Arena, G.1    Rossi, G.2    Minervini, M.M.3
  • 74
    • 79955500329 scopus 로고    scopus 로고
    • Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia
    • L. Weiss, T. Melchardt, A. Egle, C. Grabmer, R. Greil, and I. Tinhofer Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia Cancer 117 10 2011 2163 2169
    • (2011) Cancer , vol.117 , Issue.10 , pp. 2163-2169
    • Weiss, L.1    Melchardt, T.2    Egle, A.3    Grabmer, C.4    Greil, R.5    Tinhofer, I.6
  • 75
    • 0028927836 scopus 로고
    • Failure of B cells of chronic lymphocytic leukemia in presenting soluble and alloantigens
    • F. Dazzi, E. D'Andrea, G. Biasi, and et al. Failure of B cells of chronic lymphocytic leukemia in presenting soluble and alloantigens Clin Immunol Immunopathol. 75 1 1995 26 32
    • (1995) Clin Immunol Immunopathol. , vol.75 , Issue.1 , pp. 26-32
    • Dazzi, F.1    D'Andrea, E.2    Biasi, G.3
  • 77
    • 0035160749 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: Correlation with phenotypic characteristics and outcome
    • L. Fayad, M.J. Keating, J.M. Reuben, and et al. Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: Correlation with phenotypic characteristics and outcome Blood 97 1 2001 256 263
    • (2001) Blood , vol.97 , Issue.1 , pp. 256-263
    • Fayad, L.1    Keating, M.J.2    Reuben, J.M.3
  • 78
    • 0037348740 scopus 로고    scopus 로고
    • Abnormal T-cell function in B-cell chronic lymphocytic leukaemia
    • S. Scrivener, R.V. Goddard, E.R. Kaminski, and A.G. Prentice Abnormal T-cell function in B-cell chronic lymphocytic leukaemia Leuk Lymphoma 44 3 2003 383 389
    • (2003) Leuk Lymphoma , vol.44 , Issue.3 , pp. 383-389
    • Scrivener, S.1    Goddard, R.V.2    Kaminski, E.R.3    Prentice, A.G.4
  • 79
    • 0030846220 scopus 로고    scopus 로고
    • Acquired CD40-ligand deficiency in chronic lymphocytic leukemia
    • M. Cantwell, T. Hua, J. Pappas, and T.J. Kipps Acquired CD40-ligand deficiency in chronic lymphocytic leukemia Nat Med 3 9 1997 984 989
    • (1997) Nat Med , vol.3 , Issue.9 , pp. 984-989
    • Cantwell, M.1    Hua, T.2    Pappas, J.3    Kipps, T.J.4
  • 80
    • 34247639475 scopus 로고    scopus 로고
    • CD200 expression on tumor cells suppresses antitumor immunity: New approaches to cancer immunotherapy
    • A. Kretz-Rommel, F. Qin, N. Dakappagari, and et al. CD200 expression on tumor cells suppresses antitumor immunity: New approaches to cancer immunotherapy J Immunol 178 9 2007 5595 5605
    • (2007) J Immunol , vol.178 , Issue.9 , pp. 5595-5605
    • Kretz-Rommel, A.1    Qin, F.2    Dakappagari, N.3
  • 81
    • 58549108182 scopus 로고    scopus 로고
    • Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade
    • C.P. Pallasch, S. Ulbrich, R. Brinker, M. Hallek, R.A. Uger, and C.M. Wendtner Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade Leuk Res 33 3 2009 460 464
    • (2009) Leuk Res , vol.33 , Issue.3 , pp. 460-464
    • Pallasch, C.P.1    Ulbrich, S.2    Brinker, R.3    Hallek, M.4    Uger, R.A.5    Wendtner, C.M.6
  • 82
    • 84894031954 scopus 로고    scopus 로고
    • + T-cell function is not impaired in chronic lymphocytic leukemia
    • + T-cell function is not impaired in chronic lymphocytic leukemia Blood 123 5 2014 717 724
    • (2014) Blood , vol.123 , Issue.5 , pp. 717-724
    • Te Raa, G.D.1    Pascutti, M.F.2    Garcia-Vallejo, J.J.3
  • 83
    • 46749132717 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug
    • A.G. Ramsay, A.J. Johnson, A.M. Lee, and et al. Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug J Clin Invest 118 7 2008 2427 2437
    • (2008) J Clin Invest , vol.118 , Issue.7 , pp. 2427-2437
    • Ramsay, A.G.1    Johnson, A.J.2    Lee, A.M.3
  • 84
    • 84865165316 scopus 로고    scopus 로고
    • Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: Establishing a reversible immune evasion mechanism in human cancer
    • A.G. Ramsay, A.J. Clear, R. Fatah, and J.G. Gribben Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: Establishing a reversible immune evasion mechanism in human cancer Blood 120 7 2012 1412 1421
    • (2012) Blood , vol.120 , Issue.7 , pp. 1412-1421
    • Ramsay, A.G.1    Clear, A.J.2    Fatah, R.3    Gribben, J.G.4
  • 86
    • 0031068033 scopus 로고    scopus 로고
    • + T cell subsets in chronic lymphocytic leukemia
    • + T cell subsets in chronic lymphocytic leukemia J Immunol. 158 3 1997 1482 1489
    • (1997) J Immunol. , vol.158 , Issue.3 , pp. 1482-1489
    • Serrano, D.1    Monteiro, J.2    Allen, S.L.3
  • 88
    • 78649786581 scopus 로고    scopus 로고
    • Antigens in chronic lymphocytic leukemia - implications for cell origin and leukemogenesis
    • A. Rosen, F. Murray, C. Evaldsson, and R. Rosenquist Antigens in chronic lymphocytic leukemia - implications for cell origin and leukemogenesis Semin Cancer Biol 20 6 2010 400 409
    • (2010) Semin Cancer Biol , vol.20 , Issue.6 , pp. 400-409
    • Rosen, A.1    Murray, F.2    Evaldsson, C.3    Rosenquist, R.4
  • 89
    • 84866152172 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
    • M. Duhren-von Minden, R. Ubelhart, D. Schneider, and et al. Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling Nature 489 7415 2012 309 312
    • (2012) Nature , vol.489 , Issue.7415 , pp. 309-312
    • Duhren-Von Minden, M.1    Ubelhart, R.2    Schneider, D.3
  • 91
    • 84880170261 scopus 로고    scopus 로고
    • Perspective: Assembly line immunotherapy
    • B.L. Levine, and C.H. June Perspective: Assembly line immunotherapy Nature 498 7455 2013 S17
    • (2013) Nature , vol.498 , Issue.7455 , pp. S17
    • Levine, B.L.1    June, C.H.2
  • 92
    • 84897960533 scopus 로고    scopus 로고
    • Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy
    • D.M. Barrett, N. Singh, X. Liu, and et al. Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy Cytotherapy 16 5 2014 619 630
    • (2014) Cytotherapy , vol.16 , Issue.5 , pp. 619-630
    • Barrett, D.M.1    Singh, N.2    Liu, X.3
  • 95
    • 84873050511 scopus 로고    scopus 로고
    • IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
    • N. Cieri, B. Camisa, F. Cocchiarella, and et al. IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors Blood 121 4 2013 573 584
    • (2013) Blood , vol.121 , Issue.4 , pp. 573-584
    • Cieri, N.1    Camisa, B.2    Cocchiarella, F.3
  • 96
    • 79956149133 scopus 로고    scopus 로고
    • Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies
    • H. Singh, M.J. Figliola, M.J. Dawson, and et al. Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies Cancer Res 71 10 2011 3516 3527
    • (2011) Cancer Res , vol.71 , Issue.10 , pp. 3516-3527
    • Singh, H.1    Figliola, M.J.2    Dawson, M.J.3
  • 97
    • 23444445913 scopus 로고    scopus 로고
    • IL-21 influences the frequency, phenotype, and affinity of the antigen-specific CD8 T cell response
    • Y. Li, M. Bleakley, and C. Yee IL-21 influences the frequency, phenotype, and affinity of the antigen-specific CD8 T cell response J Immunol 175 4 2005 2261 2269
    • (2005) J Immunol , vol.175 , Issue.4 , pp. 2261-2269
    • Li, Y.1    Bleakley, M.2    Yee, C.3
  • 98
    • 85047696817 scopus 로고    scopus 로고
    • Retroviral transduction of human peripheral blood lymphocytes with Bcl-X(L) promotes in vitro lymphocyte survival in pro-apoptotic conditions
    • D. Eaton, D.E. Gilham, A. O'Neill, and R.E. Hawkins Retroviral transduction of human peripheral blood lymphocytes with Bcl-X(L) promotes in vitro lymphocyte survival in pro-apoptotic conditions Gene Ther 9 8 2002 527 535
    • (2002) Gene Ther , vol.9 , Issue.8 , pp. 527-535
    • Eaton, D.1    Gilham, D.E.2    O'Neill, A.3    Hawkins, R.E.4
  • 99
    • 84887264025 scopus 로고    scopus 로고
    • Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection
    • J.A. Fraietta, Y.M. Mueller, G. Yang, and et al. Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection PLoS Pathog 9 10 2013 e1003658
    • (2013) PLoS Pathog , vol.9 , Issue.10 , pp. e1003658
    • Fraietta, J.A.1    Mueller, Y.M.2    Yang, G.3
  • 100
    • 0035437179 scopus 로고    scopus 로고
    • Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential
    • N. Rufer, M. Migliaccio, J. Antonchuk, R.K. Humphries, E. Roosnek, and P.M. Lansdorp Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential Blood 98 3 2001 597 603
    • (2001) Blood , vol.98 , Issue.3 , pp. 597-603
    • Rufer, N.1    Migliaccio, M.2    Antonchuk, J.3    Humphries, R.K.4    Roosnek, E.5    Lansdorp, P.M.6
  • 101
    • 0028031971 scopus 로고
    • Transforming growth factor beta as endogenous growth inhibitor of chronic lymphocytic leukemia B cells
    • M. Lotz, E. Ranheim, and T.J. Kipps Transforming growth factor beta as endogenous growth inhibitor of chronic lymphocytic leukemia B cells J Exp Med. 179 3 1994 999 1004
    • (1994) J Exp Med , vol.179 , Issue.3 , pp. 999-1004
    • Lotz, M.1    Ranheim, E.2    Kipps, T.J.3
  • 102
    • 0036566184 scopus 로고    scopus 로고
    • Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity
    • C.M. Bollard, C. Rossig, M.J. Calonge, and et al. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity Blood 99 9 2002 3179 3187
    • (2002) Blood , vol.99 , Issue.9 , pp. 3179-3187
    • Bollard, C.M.1    Rossig, C.2    Calonge, M.J.3
  • 103
    • 84863382868 scopus 로고    scopus 로고
    • Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo
    • C. Liu, C.M. Lewis, Y. Lou, and et al. Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo J Immunother 35 3 2012 276 282
    • (2012) J Immunother , vol.35 , Issue.3 , pp. 276-282
    • Liu, C.1    Lewis, C.M.2    Lou, Y.3
  • 104
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • S.L. Topalian, F.S. Hodi, J.R. Brahmer, and et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer N Engl J Med 366 26 2012 2443 2454
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 105
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • J.R. Brahmer, S.S. Tykodi, L.Q. Chow, and et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer N Engl J Med 366 26 2012 2455 2465
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 106
    • 84896693794 scopus 로고    scopus 로고
    • PI3Kdelta inhibition by idelalisib in patients with relapsed indolent lymphoma
    • A.K. Gopal, B.S. Kahl, S. de Vos, and et al. PI3Kdelta inhibition by idelalisib in patients with relapsed indolent lymphoma N Engl J Med 370 11 2014 1008 1018
    • (2014) N Engl J Med , vol.370 , Issue.11 , pp. 1008-1018
    • Gopal, A.K.1    Kahl, B.S.2    De Vos, S.3
  • 107
    • 84888216911 scopus 로고    scopus 로고
    • Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
    • J.A. Dubovsky, K.A. Beckwith, G. Natarajan, and et al. Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes Blood 122 15 2013 2539 2549
    • (2013) Blood , vol.122 , Issue.15 , pp. 2539-2549
    • Dubovsky, J.A.1    Beckwith, K.A.2    Natarajan, G.3
  • 108
    • 84890207337 scopus 로고    scopus 로고
    • T cells expressing chimeric antigen receptors can cause anaphylaxis in humans
    • M.V. Maus, A.R. Haas, G.L. Beatty, and et al. T cells expressing chimeric antigen receptors can cause anaphylaxis in humans Cancer Immunol Res 1 1 2013 26 31
    • (2013) Cancer Immunol Res , vol.1 , Issue.1 , pp. 26-31
    • Maus, M.V.1    Haas, A.R.2    Beatty, G.L.3
  • 109
    • 84933510694 scopus 로고    scopus 로고
    • CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
    • S.L. Maude, D.T. Teachey, D.L. Porter, and S.A. Grupp CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia Blood 125 26 2015 4017 4023
    • (2015) Blood , vol.125 , Issue.26 , pp. 4017-4023
    • Maude, S.L.1    Teachey, D.T.2    Porter, D.L.3    Grupp, S.A.4
  • 111
    • 84879480191 scopus 로고    scopus 로고
    • Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells
    • M. Hudecek, M.T. Lupo-Stanghellini, P.L. Kosasih, and et al. Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells Clin Cancer Res 19 12 2013 3153 3164
    • (2013) Clin Cancer Res , vol.19 , Issue.12 , pp. 3153-3164
    • Hudecek, M.1    Lupo-Stanghellini, M.T.2    Kosasih, P.L.3
  • 112
    • 78649461928 scopus 로고    scopus 로고
    • The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
    • M. Hudecek, T.M. Schmitt, S. Baskar, and et al. The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor Blood 116 22 2010 4532 4541
    • (2010) Blood , vol.116 , Issue.22 , pp. 4532-4541
    • Hudecek, M.1    Schmitt, T.M.2    Baskar, S.3
  • 113
    • 84901703340 scopus 로고    scopus 로고
    • Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells
    • S. Gill, S.K. Tasian, M. Ruella, and et al. Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells Blood 123 15 2014 2343 2354
    • (2014) Blood , vol.123 , Issue.15 , pp. 2343-2354
    • Gill, S.1    Tasian, S.K.2    Ruella, M.3
  • 114
    • 84888226232 scopus 로고    scopus 로고
    • T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia
    • A. Mardiros, C. Dos Santos, T. McDonald, and et al. T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia Blood 122 18 2013 3138 3148
    • (2013) Blood , vol.122 , Issue.18 , pp. 3138-3148
    • Mardiros, A.1    Dos Santos, C.2    McDonald, T.3
  • 115
    • 84888270638 scopus 로고    scopus 로고
    • CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma
    • M. Casucci, B. Nicolis di Robilant, L. Falcone, and et al. CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma Blood 122 20 2013 3461 3472
    • (2013) Blood , vol.122 , Issue.20 , pp. 3461-3472
    • Casucci, M.1    Nicolis Di Robilant, B.2    Falcone, L.3
  • 116
    • 84860718270 scopus 로고    scopus 로고
    • Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells
    • 132ra153
    • J. Scholler, T.L. Brady, G. Binder-Scholl, and et al. Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells Sci Transl Med 4 132 2012 132ra153
    • (2012) Sci Transl Med , vol.4 , Issue.132
    • Scholler, J.1    Brady, T.L.2    Binder-Scholl, G.3
  • 118
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
    • M.E. Dudley, J.R. Wunderlich, J.C. Yang, and et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma J Clin Oncol 23 10 2005 2346 2357
    • (2005) J Clin Oncol , vol.23 , Issue.10 , pp. 2346-2357
    • Dudley, M.E.1    Wunderlich, J.R.2    Yang, J.C.3
  • 119
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
    • J.S. Miller, Y. Soignier, A. Panoskaltsis-Mortari, and et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer Blood 105 8 2005 3051 3057
    • (2005) Blood , vol.105 , Issue.8 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 120
    • 84878259075 scopus 로고    scopus 로고
    • +) T cell responses by regulating interferon signaling
    • +) T cell responses by regulating interferon signaling Nat Immunol 14 6 2013 593 602
    • (2013) Nat Immunol , vol.14 , Issue.6 , pp. 593-602
    • Gracias, D.T.1    Stelekati, E.2    Hope, J.L.3
  • 121
    • 84876746489 scopus 로고    scopus 로고
    • + T cell responses to virus infection and cancer
    • + T cell responses to virus infection and cancer Immunity 38 4 2013 742 753
    • (2013) Immunity , vol.38 , Issue.4 , pp. 742-753
    • Dudda, J.C.1    Salaun, B.2    Ji, Y.3
  • 122
    • 84920983137 scopus 로고    scopus 로고
    • + T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic gammac cytokines
    • + T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic gammac cytokines Proc Natl Acad Sci USA 112 2 2014 476 481
    • (2014) Proc Natl Acad Sci USA , vol.112 , Issue.2 , pp. 476-481
    • Ji, Y.1    Wrzesinski, C.2    Yu, Z.3
  • 123
    • 67650360757 scopus 로고    scopus 로고
    • Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of Costimulated autologous T cells
    • A.P. Rapoport, E.A. Stadtmauer, N. Aqui, and et al. Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of Costimulated autologous T cells Clin Cancer Res 15 13 2009 4499 4507
    • (2009) Clin Cancer Res , vol.15 , Issue.13 , pp. 4499-4507
    • Rapoport, A.P.1    Stadtmauer, E.A.2    Aqui, N.3
  • 124
    • 84871256981 scopus 로고    scopus 로고
    • Adoptive transfer of autologous T cells improves T-cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma
    • S.A. Grupp, E.L. Prak, J. Boyer, and et al. Adoptive transfer of autologous T cells improves T-cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma Clin Cancer Res 18 24 2012 6732 6741
    • (2012) Clin Cancer Res , vol.18 , Issue.24 , pp. 6732-6741
    • Grupp, S.A.1    Prak, E.L.2    Boyer, J.3


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