Crystal structure of the deglycating enzyme Amadoriase I in its free form and substrate-bound complex

Proteins: Structure, Function and Bioinformatics

Volumn 84, Issue 6, 2016, Pages 744-758

  Rigoldi, Federica ^a   Gautieri, Alfonso ^a   Dalle Vedove, Andrea ^a,b   Lucarelli, Anna Paola ^b   Vesentini, Simone ^a   Parisini, Emilio ^b  

^a POLITECNICO DI MILANO   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Deglycating enzyme; Enzyme structure; Glycation; Molecular modeling; Protein crystallization

Indexed keywords

AMADORIASE I; AMINE OXIDASE (FLAVIN CONTAINING); UNCLASSIFIED DRUG; AMADORIASE; FRUCTOSYL-LYSINE; LYSINE; OXIDOREDUCTASE; PROTEIN BINDING;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; ASPERGILLUS FUMIGATUS; BETA SHEET; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DEGLYCATION; DIFFUSION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GLYCATION; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; CHEMISTRY; ENZYMOLOGY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

AMINO ACID OXIDOREDUCTASES; AMINO ACID SEQUENCE; ASPERGILLUS FUMIGATUS; CRYSTALLOGRAPHY, X-RAY; LYSINE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 84960982142     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.25015     Document Type: Article

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