Validation of a next-generation sequencing–based protocol for 24-chromosome aneuploidy screening of blastocysts

Fertility and Sterility

Volumn 105, Issue 6, 2016, Pages 1532-1536

  Huang, Jin ^a,b   Yan, Liying ^a,b   Lu, Sijia ^c   Zhao, Nan ^a   Xie, X Sunney ^d,e   Qiao, Jie ^a,b  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Yikon Genomics ^*  (China)

^d PEKING UNIVERSITY   (China)

^e HARVARD UNIVERSITY   (United States)

Author keywords

24 chromosome aneuploidy screening; Blastocyst; multiple annealing and looping based amplification cycles (MALBAC); next generation sequencing (NGS)

Indexed keywords

ANEUPLOIDY; ARTICLE; BIOPSY; BLASTOCYST; CHROMOSOME 5Q; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; EMBRYO; FEMALE; FERTILIZATION IN VITRO; GENE AMPLIFICATION; GENETIC SCREENING; GENOTYPE; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MULTIPLE ANNEALING AND LOOPING BASED AMPLIFICATION CYCLE; MULTIPLE PREGNANCY; NEXT GENERATION SEQUENCING; PREDICTIVE VALUE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; RECIPROCAL CHROMOSOME TRANSLOCATION; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; SUPERNUMERARY CHROMOSOME; DNA MICROARRAY; MALE; PATHOLOGY; PHYSIOLOGY; PREIMPLANTATION GENETIC DIAGNOSIS; PROCEDURES; STANDARDS; VALIDATION STUDY;

ANEUPLOIDY; BLASTOCYST; FEMALE; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREIMPLANTATION DIAGNOSIS;

EID: 84960977083     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2016.01.040     Document Type: Article

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