Thyroid hormone-disrupting activity and ecological risk assessment of phosphorus-containing flame retardants by in vitro, in vivo and in silico approaches

Environmental Pollution

Volumn 210, Issue , 2016, Pages 27-33

  Zhang, Quan ^a   Ji, Chenyang ^a   Yin, Xiaohui ^a,b   Yan, Lu ^a   Lu, Meiya ^a   Zhao, Meirong ^a  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b ZHEJIANG A F UNIVERSITY   (China)

Author keywords

Ecological risks; Phosphorus containing flame retardants; Reporter gene assay; Thyroid hormone disrupting effects

Indexed keywords

BINS; CELL CULTURE; ECOLOGY; GENES; HEALTH RISKS; HORMONES; PHOSPHORUS; PLANTS (BOTANY); RISK ASSESSMENT;

ANTAGONISTIC ACTIVITY; ECOLOGICAL RISK ASSESSMENT; ECOLOGICAL RISKS; EMERGING CONTAMINANT; REPORTER GENE ASSAYS; THYROID HORMONES; TRI-BUTYL PHOSPHATE; TRICRESYL PHOSPHATES;

FLAME RETARDANTS;

ENDOCRINE DISRUPTOR; FLAME RETARDANT; PHOSPHORUS; THYROID HORMONE DISRUPTOR; TRIBUTYL PHOSPHATE; TRICRESYL PHOSPHATE; TRIPHENYL PHOSPHATE; TRIS [2 BUTOXYETHYL]PHOSPHATE; TRIS [2 CHLORO 1 [CHLOROMETHYL]ETHYL]PHOSPHATE; TRIS [2 CHLOROETHYL]PHOSPHATE; TRIS [2 CHLOROISOPROPYL]PHOSPHATE; TRIS [2 ETHYLHEXYL]PHOSPHATE; TRIS [2,3 DIBROMOPROPYL]PHOSPHATE; UNCLASSIFIED DRUG; ORGANOPHOSPHATE; THYROID HORMONE RECEPTOR BETA;

BIOTA; GENE; HEALTH RISK; HORMONE; PHOSPHORUS; RISK ASSESSMENT;

ACUTE TOXICITY; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONGENITAL MALFORMATION; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; ECOLOGICAL PROCEDURES; EMBRYO; EMBRYOTOXICITY; HYPERPIGMENTATION; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DOCKING; MORTALITY RATE; MOUSE; NONHUMAN; POLLUTANT; RAT; RISK ASSESSMENT; TERATOGENESIS; TERATOGENICITY; XENOPUS TROPICALIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CHO CELL LINE; COMPUTER SIMULATION; CRICETULUS; ECOLOGY; ENVIRONMENT; HUMAN; XENOPUS;

XENOPUS TROPICALIS;

ANIMALS; CHO CELLS; COMPUTER SIMULATION; CRICETULUS; ECOLOGY; ENVIRONMENT; FLAME RETARDANTS; HUMANS; MOLECULAR DOCKING SIMULATION; ORGANOPHOSPHATES; RATS; RISK ASSESSMENT; THYROID HORMONE RECEPTORS BETA; XENOPUS;

EID: 84960929141     PISSN: 02697491     EISSN: 18736424     Source Type: Journal    
DOI: 10.1016/j.envpol.2015.11.051     Document Type: Article

References (41)

1. J. Annamalai, and V. Namasivayam Endocrine disrupting chemicals in the atmosphere: their effects on humans and wildlife Environ. Int. 76 2015 78 97
2. R.C. Bicho, F.C. Santos, M.F. Goncalves, A.M. Soares, and M.J. Amorim Enchytraeid reproduction test(PLUS): hatching, growth and full life cycle test-an optional multi-endpoint test with Enchytraeus crypticus Ecotoxicology 24 2015 1053 1063
3. M. Colicchia, L. Campagnolo, E. Baldini, S. Ulisse, H. Valensise, and C. Moretti Molecular basis of thyrotropin and thyroid hormone action during implantation and early development Hum. Reprod. Update 20 2014 884 904
4. L.G. Costa, R. de Laat, S. Tagliaferri, and C. Pellacani A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity Toxicol. Lett. 230 2014 282 294
5. R.S. Dezonne, F.R. Lima, A.G. Trentin, and F.C. Gomes Thyroid hormone and astroglia: endocrine control of the neural environment J. Neuroendocrinol. 27 2015 435 445
6. L.V. Dishaw, L.J. Macaulay, S.C. Roberts, and H.M. Stapleton Exposures, mechanisms, and impacts of endocrine-active flame retardants Curr. Opin. Pharmacol. 19 2014 125 133
7. K.M. Gabrielsen, J.S. Krokstad, G.D. Villanger, D.A.D. Blair, M.J. Obregon, C. Sonne, R. Dietz, R.J. Letcher, and B.M. Jenssen Thyroid hormones and deiodinase activity in plasma and tissues in relation to high levels of organohalogen contaminants in East Greenland polar bears (Ursus maritimus) Environ. Res. 136 2015 413 423
8. Y. Gao, X. Li, and L.H. Guo Assessment of estrogenic activity of perfluoroalkyl acids based on ligand-induced conformation state of human estrogen receptor Environ. Sci. Technol. 47 2013 634 641
9. Y. Guo, and B. Zhou Thyroid endocrine system disruption by pentachlorophenol: an in vitro and in vivo assay Aquat. Toxicol. 142-143 2013 138 145
10. A.C. Gutleb, I.A. Meerts, J.H. Bergsma, M. Schriks, and A.J. Murk T-Screen as a tool to identify thyroid hormone receptor active compounds Environ. Toxicol. Phar. 19 2005 231 238
11. R. Guyot, F. Chatonnet, B. Gillet, S. Hughes, and F. Flamant Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells Toxicology 325 2014 125 132
12. E. Higley, A.R. Tompsett, J.P. Giesy, M. Hecker, and S. Wiseman Effects of triphenyltin on growth and development of the wood frog (Lithobates sylvaticus) Aquat. Toxicol. 144-145 2013 155 161
13. T. Kanno, H. Yanase, Y. Sugata, and K. Shigehara Flame resistant Nylon-6,6 composites with improved mechanical strength by the combination of additive- and reactive-type flame retardants Polym. J. 39 2007 347 358
14. J.W. Kim, T. Isobe, M. Muto, N.M. Tue, K. Katsura, G. Malarvannan, A. Sudaryanto, K.H. Chang, M. Prudente, P.H. Viet, S. Takahashi, and S. Tanabe Organophosphorus flame retardants (PFRs) in human breast milk from several Asian countries Chemosphere 116 2014 91 97
15. S. Kim, J. Jung, I. Lee, D. Jung, H. Youn, and K. Choi Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines Aquat. Toxicol. 160 2015 188 196
16. H. Kojima, E. Katsura, S. Takeuchi, K. Niiyama, and K. Kobayashi Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using chinese hamster ovary cells Environ. Health. Persp 112 2003 524 531
17. H. Kojima, S. Takeuchi, N. Uramaru, K. Sugihara, T. Yoshida, and S. Kitamura Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells Environ. Health. Persp 117 2009 1210 1218
18. H. Kojima, S. Takeuchi, T. Itoh, M. Iida, S. Kobayashi, and T. Yoshida In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors Toxicology 314 2013 76 83
19. X. Liu, K. Ji, and K. Choi Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish Aquat. Toxicol. 114-115 2012 173 181
20. C. Liu, Q. Wang, K. Liang, J. Liu, B. Zhou, X. Zhang, H. Liu, J.P. Giesy, and H. Yu Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae Aquat. Toxicol. 128-129 2013 147 157
21. M. Lu, J. Du, P. Zhou, H. Chen, C. Lu, and Q. Zhang Endocrine disrupting potential of fipronil and its metabolite in reporter gene assays Chemosphere 120 2015 246 251
22. T. Reemtsma, J.B. Quintana, R. Rodil, M. García-López, and I. Rodríguez Organophosphorus flame retardants and plasticizers in water and air I. Occurrence and fate. TrAC-trend Anal. Chem. 27 2008 727 737
23. M. Schriks, C.M. Vrabie, A.C. Gutleb, E.J. Faassen, I.M. Rietjens, and A.J. Murk T-screen to quantify functional potentiating, antagonistic and thyroid hormone-like activities of poly halogenated aromatic hydrocarbons (PHAHs) Toxicol. Vitro 20 2006 490 498
24. M. Shim, J.Y. Bae, Y.J. Lee, and M.J. Ahn Tectoridin from Maackia amurensis modulates both estrogen and thyroid receptors Phytomedicine 21 2014 602 606
25. A.M. Sundkvist, U. Olofsson, and P. Haglund Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milk J. Environ. Monit. 12 2010 943 951
26. S. Tajima, A. Araki, T. Kawai, T. Tsuboi, Y. Ait Bamai, E. Yoshioka, A. Kanazawa, S. Cong, and R. Kishi Detection and intake assessment of organophosphate flame retardants in house dust in Japanese dwellings Sci. Total. Environ. 478 2014 190 199
27. H.C. Tang, and C.Y. Chen Investigation of the novel lead of melanocortin 1 receptor for pigmentary disorders Evid-Based. Compl. Alt. 2014 2014 254678
28. I. van der Veen, and J. de Boer Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis Chemosphere 88 2012 1119 1153
29. C. Wang, T. Wang, W. Liu, T. Ruan, Q. Zhou, J. Liu, A. Zhang, B. Zhao, and G. Jiang The in vitro estrogenic activities of polyfluorinated iodine alkanes Environ. Health. Persp. 120 2012 119 125
30. Q. Wang, K. Liang, J. Liu, L. Yang, Y. Guo, C. Liu, and B. Zhou Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis Aquat. Toxicol. 126 2013 207 213
31. Q. Wang, J.C. Lam, J. Han, X. Wang, Y. Guo, P.K. Lam, and B. Zhou Developmental exposure to the organophosphorus flame retardant tris(1,3-dichloro-2-propyl) phosphate: estrogenic activity, endocrine disruption and reproductive effects on zebrafish Aquat. Toxicol. 160 2015 163 171
32. T. Xu, J. Zhao, D. Yin, Q. Zhao, and B. Dong High-throughput RNA sequencing reveals the effects of 2,2',4,4' -tetrabromodiphenyl ether on retina and bone development of zebrafish larvae BMC. Genomics 16 2015 23
33. X.-J. Yan, H. He, Y. Peng, X.-M. Wang, Z.-Q. Gao, S.-G. Yang, and C. Sun Determination of organophosphorus flame retardants in surface water by solid phase extraction coupled with gas chromatography-mass spectrometry Chin. J. Anal. Chem. 40 2012 1693 1697
34. F. Yang, J. Ding, W. Huang, W. Xie, and W. Liu Particle size-specific distributions and preliminary exposure assessments of organophosphate flame retardants in office air particulate matter Environ. Sci. Technol. 48 2014 63 70
35. L.Q. Yu, Z.H. Han, and C.S. Liu A review on the effects of PBDEs on thyroid and reproduction systems in fish Gen. Comp. Endocr. 219 2015 64 73
36. W. Zeng, Y. Wang, Z. Liu, A. Khanniche, Q. Hu, Y. Feng, W. Ye, J. Yang, S. Wang, L. Zhou, H. Shen, and Y. Wang Long-term exposure to decabrominated diphenyl ether impairs CD8 T-cell function in adult mice Cell. Mol. Immunol. 11 2014 367 376
37. Q. Zhang, C. Wang, X. Zhang, D. Jin, C. Huang, and M. Zhao Enantioselective aquatic toxicity of current chiral pesticides J. Environ. Monit. 14 2012 465 472
38. Q. Zhang, M. Lu, X. Dong, C. Wang, C. Zhang, W. Liu, and M. Zhao Potential estrogenic effects of phosphorus-containing flame retardants Environ. Sci. Technol. 48 2014 6995 7001
39. Q. Zhang, M. Lu, C. Wang, J. Du, P. Zhou, and M. Zhao Characterization of estrogen receptor alpha activities in polychlorinated biphenyls by in vitro dual-luciferase reporter gene assay Environ. Pollut. 189 2014 169 175
40. Q. Zhang, J. Ye, J. Chen, H. Xu, C. Wang, and M. Zhao Risk assessment of polychlorinated biphenyls and heavy metals in soils of an abandoned e-waste site in China Environ. Pollut. 185 2014 258 265
41. J. Zhu, L. Yu, L. Wu, L. Hu, and H. Shi Unexpected phenotypes of malformations induced in Xenopus tropicalis embryos by combined exposure to triphenyltin and 9-cis-retinoic acid J. Environ. Sci-China 26 2014 643 649