Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution

Journal of Allergy and Clinical Immunology

Volumn 137, Issue 3, 2016, Pages 797-805.e5

  Somineni, Hari K ^a   Zhang, Xue ^a   Biagini Myers, Jocelyn M ^a   Kovacic, Melinda Butsch ^a,c   Ulm, Ashley ^a   Jurcak, Noelle ^b   Ryan, Patrick H ^a,c   Khurana Hershey, Gurjit K ^a   Ji, Hong ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

5 hmC; asthma; cross tissue marker; DNA methylation; nasal epithelial cells; TET1; traffic related air pollution

Indexed keywords

5 METHYLCYTOSINE; CYTOCHROME P450 1A1; DIOXYGENASE; DNA; HEME OXYGENASE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TEN ELEVEN TRANSLOCATION 1 ENZYME; THYMIC STROMAL LYMPHOPOIETIN; UNCLASSIFIED DRUG; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA BINDING PROTEIN; EXHAUST GAS; MIXED FUNCTION OXIDASE; ONCOPROTEIN; TET1 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AFRICAN AMERICAN; ARTICLE; ASTHMA; ASTHMATIC STATE; BRONCHUS MUCOSA; CHILD; CONTROLLED STUDY; CPG ISLAND; CROSS-SECTIONAL STUDY; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EXHAUST GAS; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; PYROSEQUENCING; RESPIRATORY EPITHELIUM; SALIVA; SIBLING; UPREGULATION; ADVERSE EFFECTS; AIR POLLUTION; ALLELE; ANALOGS AND DERIVATIVES; CASE CONTROL STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENETIC EPIGENESIS; GENETICS; METABOLISM; NOSE MUCOSA; RISK FACTOR;

ADOLESCENT; AIR POLLUTION; ALLELES; ASTHMA; CASE-CONTROL STUDIES; CHILD; CPG ISLANDS; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION; HUMANS; MALE; MIXED FUNCTION OXYGENASES; NASAL MUCOSA; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; RISK FACTORS; RNA, MESSENGER; VEHICLE EMISSIONS;

EID: 84960898470     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.10.021     Document Type: Article

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