SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons

Human Molecular Genetics

Volumn 25, Issue 3, 2016, Pages 514-523

  Patitucci, Teresa N ^a   Ebert, Allison D ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CATALASE; OXYGEN; REACTIVE OXYGEN METABOLITE; SURVIVAL MOTOR NEURON PROTEIN; GCLC PROTEIN, HUMAN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2;

ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOENERGY; CELL DIFFERENTIATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; MOTONEURON; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SPINAL MUSCULAR ATROPHY; UPREGULATION; ANTAGONISTS AND INHIBITORS; GENE EXPRESSION REGULATION; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MITOCHONDRION; NEURAL STEM CELL; PATHOLOGY; PRIMARY CELL CULTURE; SPINAL CORD;

ASTROCYTES; CATALASE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE PEROXIDASE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MITOCHONDRIA; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; NAD(P)H DEHYDROGENASE (QUINONE); NEURAL STEM CELLS; NF-E2-RELATED FACTOR 2; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84960888922     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv489     Document Type: Article

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