Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy

Cell Research

Volumn 23, Issue 3, 2013, Pages 378-393

  Wang, Zhi Bo ^a   Zhang, Xiaoqing ^b   Li, Xue Jun ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

disease modeling; human embryonic stem cells; RNA interference; spinal motor neuron; spinal muscular atrophy

Indexed keywords

ISOPROTEIN; SURVIVAL MOTOR NEURON PROTEIN; SURVIVAL MOTOR NEURON PROTEIN 1; SURVIVAL MOTOR NEURON PROTEIN 2;

ARTICLE; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; EMBRYONIC STEM CELL; FLOW CYTOMETRY; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MOTONEURON; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL MUSCULAR ATROPHY; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMN COMPLEX PROTEINS; SURVIVAL OF MOTOR NEURON 1 PROTEIN; SURVIVAL OF MOTOR NEURON 2 PROTEIN;

EID: 84874649253     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2012.166     Document Type: Article

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