Improvement of Neuromuscular Synaptic Phenotypes without Enhanced Survival and Motor Function in Severe Spinal Muscular Atrophy Mice Selectively Rescued in Motor Neurons

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Paez Colasante, Ximena ^a,b   Seaberg, Bonnie ^a   Martinez, Tara L ^c   Kong, Lingling ^c   Sumner, Charlotte J ^c   Rimer, Mendell ^a,b  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE ACETYLTRANSFERASE CRE RECOMBINASE; CRE RECOMBINASE; HB9 CRE RECOMBINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; GENETIC TRANSCRIPTION; LOCOMOTION; MOTONEURON; MOTOR PERFORMANCE; MOUSE; MUSCLE DENERVATION; NERVE ENDING; NEUROFILAMENT; NEUROMUSCULAR SYNAPSE; NONHUMAN; PHENOTYPE; PRESYNAPTIC NERVE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD MOTONEURON; SPINAL MUSCULAR ATROPHY;

ANIMALS; DNA PRIMERS; GENOTYPE; MICE; MOTOR ENDPLATE; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; SMN COMPLEX PROTEINS; SURVIVAL ANALYSIS; SYNAPSES;

EID: 84884512903     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075866     Document Type: Article

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