IL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa

Journal of Allergy and Clinical Immunology

Volumn 137, Issue 5, 2016, Pages 1514-1524

  Lam, Emily P S ^a,h   Kariyawasam, Harsha H ^b,h   Rana, Batika M J ^c,h   Durham, Stephen R ^d,h   McKenzie, Andrew N J ^c   Powell, Nicholas ^e   Orban, Nara ^d   Lennartz Walker, Melissa ^a,h   Hopkins, Claire ^g   Ying, Sun ^a   Rimmer, Joanne ^b   Lund, Valerie J ^b   Cousins, David J ^f,h   Till, Stephen J ^a,h  

^a GUY S HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF LEICESTER   (United Kingdom)

^g GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^h KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Chronic rhinosinusitis with nasal polyps; IL 17RB; IL 25; IL 33; microarray; nasal mucosa; ST2; T cell phenotype; T cell receptor V repertoire; TH17 cells; TH2 cells

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 25; INTERLEUKIN 25 RECEPTOR; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; INTERLEUKIN 5; INTERLEUKIN RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; IL25 PROTEIN, HUMAN; IL33 PROTEIN, HUMAN; INTERLEUKIN 17;

ARTICLE; CELL SURFACE; CHRONIC RHINOSINUSITIS; CLONE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; GENE EXPRESSION ASSAY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY; IMMUNOASSAY ANALYZER; IN VITRO STUDY; NASAL BIOPSY; NOSE MUCOSA; NOSE POLYP; PHENOTYPE; POLYPECTOMY; PRIORITY JOURNAL; TH17 CELL; TH2 CELL; CHRONIC DISEASE; EOSINOPHILIA; IMMUNOLOGY; RHINITIS; SINUSITIS;

CHRONIC DISEASE; EOSINOPHILIA; HUMANS; INTERLEUKIN-17; INTERLEUKIN-33; NASAL MUCOSA; NASAL POLYPS; RHINITIS; SINUSITIS; TH17 CELLS; TH2 CELLS;

EID: 84960886647     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.10.019     Document Type: Article

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