Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway

World Journal of Gastroenterology

Volumn 22, Issue 11, 2016, Pages 3186-3195

  Kong, Gui Mei ^a   Tao, Wen Hua ^a   Diao, Ya Li ^a,b   Fang, Peng Hua ^a   Wang, Ji Jun ^a   Bo, Ping ^a   Qian, Feng ^a  

^a YANGZHOU UNIVERSITY   (China)

^b Department of Gastroenterology   (China)

Author keywords

Apoptosis; Cytochrome C; Gastric cancer; Melittin; Mitochondrial

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 8; CYTOCHROME C; ENDONUCLEASE G; FAS ANTIGEN; MELITTIN; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; METHYL THIAZOLYL TETRAZOLIUM ASSAY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MORPHOLOGY; PROTEIN EXPRESSION; SGC 7901 CELL LINE; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; CELL SHAPE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; STOMACH NEOPLASMS; TIME FACTOR; TUMOR CELL LINE; ULTRASTRUCTURE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MELITTEN; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TIME FACTORS;

EID: 84960869737     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v22.i11.3186     Document Type: Article

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