-
1
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
B.J. Druker, M. Talpaz, D.J. Resta, B. Peng, E. Buchdunger, J.M. Ford, N.B. Lydon, H. Kantarjian, R. Capdeville, S. Ohno-Jones, and C.L. Sawyers Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia N Engl J Med 344 2001 1031 1037
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
2
-
-
84922373207
-
The landscape of kinase fusions in cancer
-
N. Stransky, E. Cerami, S. Schalm, J.L. Kim, and C. Lengauer The landscape of kinase fusions in cancer Nat Commun 5 2014 4846
-
(2014)
Nat Commun
, vol.5
, pp. 4846
-
-
Stransky, N.1
Cerami, E.2
Schalm, S.3
Kim, J.L.4
Lengauer, C.5
-
3
-
-
84929852263
-
The landscape and therapeutic relevance of cancer-associated transcript fusions
-
K. Yoshihara, Q. Wang, W. Torres-Garcia, S. Zheng, R. Vegesna, H. Kim, and R.G. Verhaak The landscape and therapeutic relevance of cancer-associated transcript fusions Oncogene 34 2014 4845 4854
-
(2014)
Oncogene
, vol.34
, pp. 4845-4854
-
-
Yoshihara, K.1
Wang, Q.2
Torres-Garcia, W.3
Zheng, S.4
Vegesna, R.5
Kim, H.6
Verhaak, R.G.7
-
4
-
-
84863338079
-
ROS1 rearrangements define a unique molecular class of lung cancers
-
K. Bergethon, A.T. Shaw, S.H. Ou, R. Katayama, C.M. Lovly, N.T. McDonald, P.P. Massion, C. Siwak-Tapp, A. Gonzalez, R. Fang, E.J. Mark, J.M. Batten, H. Chen, K.D. Wilner, E.L. Kwak, J.W. Clark, D.P. Carbone, H. Ji, J.A. Engelman, M. Mino-Kenudson, W. Pao, and A.J. Iafrate ROS1 rearrangements define a unique molecular class of lung cancers J Clin Oncol 30 2012 863 870
-
(2012)
J Clin Oncol
, vol.30
, pp. 863-870
-
-
Bergethon, K.1
Shaw, A.T.2
Ou, S.H.3
Katayama, R.4
Lovly, C.M.5
McDonald, N.T.6
Massion, P.P.7
Siwak-Tapp, C.8
Gonzalez, A.9
Fang, R.10
Mark, E.J.11
Batten, J.M.12
Chen, H.13
Wilner, K.D.14
Kwak, E.L.15
Clark, J.W.16
Carbone, D.P.17
Ji, H.18
Engelman, J.A.19
Mino-Kenudson, M.20
Pao, W.21
Iafrate, A.J.22
more..
-
5
-
-
84878858856
-
Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas
-
A. Drilon, L. Wang, A. Hasanovic, Y. Suehara, D. Lipson, P. Stephens, J. Ross, V. Miller, M. Ginsberg, M.F. Zakowski, M.G. Kris, M. Ladanyi, and N. Rizvi Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas Cancer Discov 3 2013 630 635
-
(2013)
Cancer Discov
, vol.3
, pp. 630-635
-
-
Drilon, A.1
Wang, L.2
Hasanovic, A.3
Suehara, Y.4
Lipson, D.5
Stephens, P.6
Ross, J.7
Miller, V.8
Ginsberg, M.9
Zakowski, M.F.10
Kris, M.G.11
Ladanyi, M.12
Rizvi, N.13
-
6
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
E.L. Kwak, Y.J. Bang, D.R. Camidge, A.T. Shaw, B. Solomon, R.G. Maki, S.H. Ou, B.J. Dezube, P.A. Janne, D.B. Costa, M. Varella-Garcia, W.H. Kim, T.J. Lynch, P. Fidias, H. Stubbs, J.A. Engelman, L.V. Sequist, W. Tan, L. Gandhi, M. Mino-Kenudson, G.C. Wei, S.M. Shreeve, M.J. Ratain, J. Settleman, J.G. Christensen, D.A. Haber, K. Wilner, R. Salgia, G.I. Shapiro, J.W. Clark, and A.J. Iafrate Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer N Engl J Med 363 2010 1693 1703
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
Maki, R.G.6
Ou, S.H.7
Dezube, B.J.8
Janne, P.A.9
Costa, D.B.10
Varella-Garcia, M.11
Kim, W.H.12
Lynch, T.J.13
Fidias, P.14
Stubbs, H.15
Engelman, J.A.16
Sequist, L.V.17
Tan, W.18
Gandhi, L.19
Mino-Kenudson, M.20
Wei, G.C.21
Shreeve, S.M.22
Ratain, M.J.23
Settleman, J.24
Christensen, J.G.25
Haber, D.A.26
Wilner, K.27
Salgia, R.28
Shapiro, G.I.29
Clark, J.W.30
Iafrate, A.J.31
more..
-
7
-
-
84911372597
-
Crizotinib in ROS1-rearranged non-small-cell lung cancer
-
A.T. Shaw, S.H. Ou, Y.J. Bang, D.R. Camidge, B.J. Solomon, R. Salgia, G.J. Riely, M. Varella-Garcia, G.I. Shapiro, D.B. Costa, R.C. Doebele, L.P. Le, Z. Zheng, W. Tan, P. Stephenson, S.M. Shreeve, L.M. Tye, J.G. Christensen, K.D. Wilner, J.W. Clark, and A.J. Iafrate Crizotinib in ROS1-rearranged non-small-cell lung cancer N Engl J Med 371 2014 1963 1971
-
(2014)
N Engl J Med
, vol.371
, pp. 1963-1971
-
-
Shaw, A.T.1
Ou, S.H.2
Bang, Y.J.3
Camidge, D.R.4
Solomon, B.J.5
Salgia, R.6
Riely, G.J.7
Varella-Garcia, M.8
Shapiro, G.I.9
Costa, D.B.10
Doebele, R.C.11
Le, L.P.12
Zheng, Z.13
Tan, W.14
Stephenson, P.15
Shreeve, S.M.16
Tye, L.M.17
Christensen, J.G.18
Wilner, K.D.19
Clark, J.W.20
Iafrate, A.J.21
more..
-
8
-
-
84857985225
-
RET, ROS1 and ALK fusions in lung cancer
-
K. Takeuchi, M. Soda, Y. Togashi, R. Suzuki, S. Sakata, S. Hatano, R. Asaka, W. Hamanaka, H. Ninomiya, H. Uehara, C.Y. Lim, Y. Satoh, S. Okumura, K. Nakagawa, H. Mano, and Y. Ishikawa RET, ROS1 and ALK fusions in lung cancer Nat Med 18 2012 378 381
-
(2012)
Nat Med
, vol.18
, pp. 378-381
-
-
Takeuchi, K.1
Soda, M.2
Togashi, Y.3
Suzuki, R.4
Sakata, S.5
Hatano, S.6
Asaka, R.7
Hamanaka, W.8
Ninomiya, H.9
Uehara, H.10
Lim, C.Y.11
Satoh, Y.12
Okumura, S.13
Nakagawa, K.14
Mano, H.15
Ishikawa, Y.16
-
9
-
-
84870748688
-
RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer
-
R. Wang, H. Hu, Y. Pan, Y. Li, T. Ye, C. Li, X. Luo, L. Wang, H. Li, Y. Zhang, F. Li, Y. Lu, Q. Lu, J. Xu, D. Garfield, L. Shen, H. Ji, W. Pao, Y. Sun, and H. Chen RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer J Clin Oncol 30 2012 4352 4359
-
(2012)
J Clin Oncol
, vol.30
, pp. 4352-4359
-
-
Wang, R.1
Hu, H.2
Pan, Y.3
Li, Y.4
Ye, T.5
Li, C.6
Luo, X.7
Wang, L.8
Li, H.9
Zhang, Y.10
Li, F.11
Lu, Y.12
Lu, Q.13
Xu, J.14
Garfield, D.15
Shen, L.16
Ji, H.17
Pao, W.18
Sun, Y.19
Chen, H.20
more..
-
10
-
-
84896492774
-
Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma
-
Y. Arai, Y. Totoki, F. Hosoda, T. Shirota, N. Hama, H. Nakamura, H. Ojima, K. Furuta, K. Shimada, T. Okusaka, T. Kosuge, and T. Shibata Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma Hepatology 59 2014 1427 1434
-
(2014)
Hepatology
, vol.59
, pp. 1427-1434
-
-
Arai, Y.1
Totoki, Y.2
Hosoda, F.3
Shirota, T.4
Hama, N.5
Nakamura, H.6
Ojima, H.7
Furuta, K.8
Shimada, K.9
Okusaka, T.10
Kosuge, T.11
Shibata, T.12
-
11
-
-
84901742112
-
Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma
-
M.J. Borad, M.D. Champion, J.B. Egan, W.S. Liang, R. Fonseca, A.H. Bryce, and et al. Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma PLoS Genet 10 2014 e1004135
-
(2014)
PLoS Genet
, vol.10
, pp. e1004135
-
-
Borad, M.J.1
Champion, M.D.2
Egan, J.B.3
Liang, W.S.4
Fonseca, R.5
Bryce, A.H.6
-
12
-
-
84886292349
-
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy
-
T. Botton, I. Yeh, T. Nelson, S.S. Vemula, A. Sparatta, M.C. Garrido, M. Allegra, S. Rocchi, P. Bahadoran, T.H. McCalmont, P.E. LeBoit, E.A. Burton, G. Bollag, R. Ballotti, and B.C. Bastian Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy Pigment Cell Melanoma Res 26 2013 845 851
-
(2013)
Pigment Cell Melanoma Res
, vol.26
, pp. 845-851
-
-
Botton, T.1
Yeh, I.2
Nelson, T.3
Vemula, S.S.4
Sparatta, A.5
Garrido, M.C.6
Allegra, M.7
Rocchi, S.8
Bahadoran, P.9
McCalmont, T.H.10
LeBoit, P.E.11
Burton, E.A.12
Bollag, G.13
Ballotti, R.14
Bastian, B.C.15
-
13
-
-
84865805666
-
Transforming fusions of FGFR and TACC genes in human glioblastoma
-
D. Singh, J.M. Chan, P. Zoppoli, F. Niola, R. Sullivan, A. Castano, E.M. Liu, J. Reichel, P. Porrati, S. Pellegatta, K. Qiu, Z. Gao, M. Ceccarelli, R. Riccardi, D.J. Brat, A. Guha, K. Aldape, J.G. Golfinos, D. Zagzag, T. Mikkelsen, G. Finocchiaro, A. Lasorella, R. Rabadan, and A. Iavarone Transforming fusions of FGFR and TACC genes in human glioblastoma Science 337 2012 1231 1235
-
(2012)
Science
, vol.337
, pp. 1231-1235
-
-
Singh, D.1
Chan, J.M.2
Zoppoli, P.3
Niola, F.4
Sullivan, R.5
Castano, A.6
Liu, E.M.7
Reichel, J.8
Porrati, P.9
Pellegatta, S.10
Qiu, K.11
Gao, Z.12
Ceccarelli, M.13
Riccardi, R.14
Brat, D.J.15
Guha, A.16
Aldape, K.17
Golfinos, J.G.18
Zagzag, D.19
Mikkelsen, T.20
Finocchiaro, G.21
Lasorella, A.22
Rabadan, R.23
Iavarone, A.24
more..
-
14
-
-
84892379425
-
Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein
-
V. Subbiah, S.N. Westin, K. Wang, D. Araujo, W.L. Wang, V.A. Miller, J.S. Ross, P.J. Stephens, G.A. Palmer, and S.M. Ali Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein J Hematol Oncol 7 2014 8
-
(2014)
J Hematol Oncol
, vol.7
, pp. 8
-
-
Subbiah, V.1
Westin, S.N.2
Wang, K.3
Araujo, D.4
Wang, W.L.5
Miller, V.A.6
Ross, J.S.7
Stephens, P.J.8
Palmer, G.A.9
Ali, S.M.10
-
15
-
-
84887445619
-
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
-
A. Vaishnavi, M. Capelletti, A.T. Le, S. Kako, M. Butaney, D. Ercan, S. Mahale, K.D. Davies, D.L. Aisner, A.B. Pilling, E.M. Berge, J. Kim, H. Sasaki, S.I. Park, G. Kryukov, L.A. Garraway, P.S. Hammerman, J. Haas, S.W. Andrews, D. Lipson, P.J. Stephens, V.A. Miller, M. Varella-Garcia, P.A. Janne, and R.C. Doebele Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer Nat Med 19 2013 1469 1472
-
(2013)
Nat Med
, vol.19
, pp. 1469-1472
-
-
Vaishnavi, A.1
Capelletti, M.2
Le, A.T.3
Kako, S.4
Butaney, M.5
Ercan, D.6
Mahale, S.7
Davies, K.D.8
Aisner, D.L.9
Pilling, A.B.10
Berge, E.M.11
Kim, J.12
Sasaki, H.13
Park, S.I.14
Kryukov, G.15
Garraway, L.A.16
Hammerman, P.S.17
Haas, J.18
Andrews, S.W.19
Lipson, D.20
Stephens, P.J.21
Miller, V.A.22
Varella-Garcia, M.23
Janne, P.A.24
Doebele, R.C.25
more..
-
16
-
-
84922341647
-
TRKing down an old oncogene in a new era of targeted therapy
-
A. Vaishnavi, A.T. Le, and R.C. Doebele TRKing down an old oncogene in a new era of targeted therapy Cancer Discov 5 2015 25 34
-
(2015)
Cancer Discov
, vol.5
, pp. 25-34
-
-
Vaishnavi, A.1
Le, A.T.2
Doebele, R.C.3
-
17
-
-
84878781242
-
Identification of targetable FGFR gene fusions in diverse cancers
-
Y.M. Wu, F. Su, S. Kalyana-Sundaram, N. Khazanov, B. Ateeq, X. Cao, R.J. Lonigro, P. Vats, R. Wang, S.F. Lin, A.J. Cheng, L.P. Kunju, J. Siddiqui, S.A. Tomlins, P. Wyngaard, S. Sadis, S. Roychowdhury, M.H. Hussain, F.Y. Feng, M.M. Zalupski, M. Talpaz, K.J. Pienta, D.R. Rhodes, D.R. Robinson, and A.M. Chinnaiyan Identification of targetable FGFR gene fusions in diverse cancers Cancer Discov 3 2013 636 647
-
(2013)
Cancer Discov
, vol.3
, pp. 636-647
-
-
Wu, Y.M.1
Su, F.2
Kalyana-Sundaram, S.3
Khazanov, N.4
Ateeq, B.5
Cao, X.6
Lonigro, R.J.7
Vats, P.8
Wang, R.9
Lin, S.F.10
Cheng, A.J.11
Kunju, L.P.12
Siddiqui, J.13
Tomlins, S.A.14
Wyngaard, P.15
Sadis, S.16
Roychowdhury, S.17
Hussain, M.H.18
Feng, F.Y.19
Zalupski, M.M.20
Talpaz, M.21
Pienta, K.J.22
Rhodes, D.R.23
Robinson, D.R.24
Chinnaiyan, A.M.25
more..
-
18
-
-
84865751880
-
Variants on a theme: A biomarker of crizotinib response in ALK-positive non-small cell lung cancer?
-
A.S. Crystal, and A.T. Shaw Variants on a theme: a biomarker of crizotinib response in ALK-positive non-small cell lung cancer? Clin Cancer Res 18 2012 4479 4481
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4479-4481
-
-
Crystal, A.S.1
Shaw, A.T.2
-
19
-
-
84865776102
-
Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants
-
J.M. Heuckmann, H. Balke-Want, F. Malchers, M. Peifer, M.L. Sos, M. Koker, L. Meder, C.M. Lovly, L.C. Heukamp, W. Pao, R. Kuppers, and R.K. Thomas Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants Clin Cancer Res 18 2012 4682 4690
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4682-4690
-
-
Heuckmann, J.M.1
Balke-Want, H.2
Malchers, F.3
Peifer, M.4
Sos, M.L.5
Koker, M.6
Meder, L.7
Lovly, C.M.8
Heukamp, L.C.9
Pao, W.10
Kuppers, R.11
Thomas, R.K.12
-
20
-
-
84902994777
-
Detection of gene rearrangements in targeted clinical next-generation sequencing
-
H.J. Abel, H. Al-Kateb, C.E. Cottrell, A.J. Bredemeyer, C.C. Pritchard, A.H. Grossmann, M.L. Wallander, J.D. Pfeifer, C.M. Lockwood, and E.J. Duncavage Detection of gene rearrangements in targeted clinical next-generation sequencing J Mol Diagn 16 2014 405 417
-
(2014)
J Mol Diagn
, vol.16
, pp. 405-417
-
-
Abel, H.J.1
Al-Kateb, H.2
Cottrell, C.E.3
Bredemeyer, A.J.4
Pritchard, C.C.5
Grossmann, A.H.6
Wallander, M.L.7
Pfeifer, J.D.8
Lockwood, C.M.9
Duncavage, E.J.10
-
21
-
-
84942939967
-
Identifying ALK rearrangements that are not detected by FISH with targeted next-generation sequencing of lung carcinoma
-
suppl; abstr 8049
-
S.M. Ali, S.H.I. Ou, J. He, N. Peled, J. Chmielecki, M.C. Pinder, and et al. Identifying ALK rearrangements that are not detected by FISH with targeted next-generation sequencing of lung carcinoma J Clin Oncol 32 2014 5s suppl; abstr 8049
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Ali, S.M.1
Ou, S.H.I.2
He, J.3
Peled, N.4
Chmielecki, J.5
Pinder, M.C.6
-
22
-
-
84942521554
-
Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other genomic testing approaches
-
A. Drilon, L. Wang, M.E. Arcila, S. Balasubramanian, J.R. Greenbowe, J.S. Ross, P. Stephens, D. Lipson, V.A. Miller, M.G. Kris, M. Ladanyi, and N.A. Rizvi Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other genomic testing approaches Clin Cancer Res 21 2015 3631 3639
-
(2015)
Clin Cancer Res
, vol.21
, pp. 3631-3639
-
-
Drilon, A.1
Wang, L.2
Arcila, M.E.3
Balasubramanian, S.4
Greenbowe, J.R.5
Ross, J.S.6
Stephens, P.7
Lipson, D.8
Miller, V.A.9
Kris, M.G.10
Ladanyi, M.11
Rizvi, N.A.12
-
23
-
-
84887491073
-
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
-
G.M. Frampton, A. Fichtenholtz, G.A. Otto, K. Wang, S.R. Downing, J. He, and et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing Nat Biotechnol 31 2013 1023 1031
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1023-1031
-
-
Frampton, G.M.1
Fichtenholtz, A.2
Otto, G.A.3
Wang, K.4
Downing, S.R.5
He, J.6
-
24
-
-
84901929258
-
Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing
-
E.A. Moskalev, J. Frohnauer, S. Merkelbach-Bruse, H.U. Schildhaus, A. Dimmler, T. Schubert, C. Boltze, H. Konig, F. Fuchs, H. Sirbu, R.J. Rieker, A. Agaimy, A. Hartmann, and F. Haller Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing Lung Cancer 84 2014 215 221
-
(2014)
Lung Cancer
, vol.84
, pp. 215-221
-
-
Moskalev, E.A.1
Frohnauer, J.2
Merkelbach-Bruse, S.3
Schildhaus, H.U.4
Dimmler, A.5
Schubert, T.6
Boltze, C.7
Konig, H.8
Fuchs, F.9
Sirbu, H.10
Rieker, R.J.11
Agaimy, A.12
Hartmann, A.13
Haller, F.14
-
25
-
-
84925411861
-
Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer
-
M. Pekar-Zlotin, F.R. Hirsch, L. Soussan-Gutman, M. Ilouze, A. Dvir, T. Boyle, M. Wynes, V.A. Miller, D. Lipson, G.A. Palmer, S.M. Ali, S. Dekel, R. Brenner, P.A. Bunn Jr., and N. Peled Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer Oncologist 20 2015 316 322
-
(2015)
Oncologist
, vol.20
, pp. 316-322
-
-
Pekar-Zlotin, M.1
Hirsch, F.R.2
Soussan-Gutman, L.3
Ilouze, M.4
Dvir, A.5
Boyle, T.6
Wynes, M.7
Miller, V.A.8
Lipson, D.9
Palmer, G.A.10
Ali, S.M.11
Dekel, S.12
Brenner, R.13
Bunn, P.A.14
Peled, N.15
-
26
-
-
84925582188
-
Anchored multiplex PCR for targeted next-generation sequencing
-
Z. Zheng, M. Liebers, B. Zhelyazkova, Y. Cao, D. Panditi, K.D. Lynch, J. Chen, H.E. Robinson, H.S. Shim, J. Chmielecki, W. Pao, J.A. Engelman, A.J. Iafrate, and L.P. Le Anchored multiplex PCR for targeted next-generation sequencing Nat Med 20 2014 1479 1484
-
(2014)
Nat Med
, vol.20
, pp. 1479-1484
-
-
Zheng, Z.1
Liebers, M.2
Zhelyazkova, B.3
Cao, Y.4
Panditi, D.5
Lynch, K.D.6
Chen, J.7
Robinson, H.E.8
Shim, H.S.9
Chmielecki, J.10
Pao, W.11
Engelman, J.A.12
Iafrate, A.J.13
Le, L.P.14
-
28
-
-
84889000676
-
Application of next generation sequencing to human gene fusion detection: Computational tools, features and perspectives
-
Q. Wang, J. Xia, P. Jia, W. Pao, and Z. Zhao Application of next generation sequencing to human gene fusion detection: computational tools, features and perspectives Brief Bioinform 14 2013 506 519
-
(2013)
Brief Bioinform
, vol.14
, pp. 506-519
-
-
Wang, Q.1
Xia, J.2
Jia, P.3
Pao, W.4
Zhao, Z.5
-
29
-
-
84964310688
-
Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data
-
C. Grasso, T. Butler, K. Rhodes, M. Quist, T.L. Neff, S. Moore, S.A. Tomlins, E. Reinig, C. Beadling, M. Andersen, and C.L. Corless Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data J Mol Diagn 17 2015 53 63
-
(2015)
J Mol Diagn
, vol.17
, pp. 53-63
-
-
Grasso, C.1
Butler, T.2
Rhodes, K.3
Quist, M.4
Neff, T.L.5
Moore, S.6
Tomlins, S.A.7
Reinig, E.8
Beadling, C.9
Andersen, M.10
Corless, C.L.11
-
30
-
-
84983535287
-
Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors
-
D.H. Hovelson, A.S. McDaniel, A.K. Cani, B. Johnson, K. Rhodes, P.D. Williams, S. Bandla, G. Bien, P. Choppa, F. Hyland, R. Gottimukkala, G. Liu, M. Manivannan, J. Schageman, E. Ballesteros-Villagrana, C.S. Grasso, M.J. Quist, V. Yadati, A. Amin, J. Siddiqui, B.L. Betz, K.E. Knudsen, K.A. Cooney, F.Y. Feng, M.H. Roh, P.S. Nelson, C.J. Liu, D.G. Beer, P. Wyngaard, A.M. Chinnaiyan, S. Sadis, D.R. Rhodes, and S.A. Tomlins Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors Neoplasia 17 2015 385 399
-
(2015)
Neoplasia
, vol.17
, pp. 385-399
-
-
Hovelson, D.H.1
McDaniel, A.S.2
Cani, A.K.3
Johnson, B.4
Rhodes, K.5
Williams, P.D.6
Bandla, S.7
Bien, G.8
Choppa, P.9
Hyland, F.10
Gottimukkala, R.11
Liu, G.12
Manivannan, M.13
Schageman, J.14
Ballesteros-Villagrana, E.15
Grasso, C.S.16
Quist, M.J.17
Yadati, V.18
Amin, A.19
Siddiqui, J.20
Betz, B.L.21
Knudsen, K.E.22
Cooney, K.A.23
Feng, F.Y.24
Roh, M.H.25
Nelson, P.S.26
Liu, C.J.27
Beer, D.G.28
Wyngaard, P.29
Chinnaiyan, A.M.30
Sadis, S.31
Rhodes, D.R.32
Tomlins, S.A.33
more..
-
31
-
-
84920103030
-
Highly sensitive amplicon-based transcript quantification by semiconductor sequencing
-
J.D. Zhang, T. Schindler, E. Kung, M. Ebeling, and U. Certa Highly sensitive amplicon-based transcript quantification by semiconductor sequencing BMC Genomics 15 2014 565
-
(2014)
BMC Genomics
, vol.15
, pp. 565
-
-
Zhang, J.D.1
Schindler, T.2
Kung, E.3
Ebeling, M.4
Certa, U.5
-
32
-
-
84873927764
-
Mouse model for ROS1-rearranged lung cancer
-
Y. Arai, Y. Totoki, H. Takahashi, H. Nakamura, N. Hama, T. Kohno, K. Tsuta, A. Yoshida, H. Asamura, M. Mutoh, F. Hosoda, H. Tsuda, and T. Shibata Mouse model for ROS1-rearranged lung cancer PLoS One 8 2013 e56010
-
(2013)
PLoS One
, vol.8
, pp. e56010
-
-
Arai, Y.1
Totoki, Y.2
Takahashi, H.3
Nakamura, H.4
Hama, N.5
Kohno, T.6
Tsuta, K.7
Yoshida, A.8
Asamura, H.9
Mutoh, M.10
Hosoda, F.11
Tsuda, H.12
Shibata, T.13
-
33
-
-
84862523863
-
Sequence analysis of mutations and translocations across breast cancer subtypes
-
S. Banerji, K. Cibulskis, C. Rangel-Escareno, K.K. Brown, S.L. Carter, A.M. Frederick, and et al. Sequence analysis of mutations and translocations across breast cancer subtypes Nature 486 2012 405 409
-
(2012)
Nature
, vol.486
, pp. 405-409
-
-
Banerji, S.1
Cibulskis, K.2
Rangel-Escareno, C.3
Brown, K.K.4
Carter, S.L.5
Frederick, A.M.6
-
34
-
-
0037402509
-
Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)
-
A. Charest, K. Lane, K. McMahon, J. Park, E. Preisinger, H. Conroy, and D. Housman Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21) Genes Chromosomes Cancer 37 2003 58 71
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 58-71
-
-
Charest, A.1
Lane, K.2
McMahon, K.3
Park, J.4
Preisinger, E.5
Conroy, H.6
Housman, D.7
-
35
-
-
79958087774
-
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
-
H. Cin, C. Meyer, R. Herr, W.G. Janzarik, S. Lambert, D.T. Jones, K. Jacob, A. Benner, H. Witt, M. Remke, S. Bender, F. Falkenstein, T.N. Van Anh, H. Olbrich, D.A. von, A. Pekrun, A.E. Kulozik, A. Gnekow, W. Scheurlen, O. Witt, H. Omran, N. Jabado, V.P. Collins, T. Brummer, R. Marschalek, P. Lichter, A. Korshunov, and S.M. Pfister Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma Acta Neuropathol 121 2011 763 774
-
(2011)
Acta Neuropathol
, vol.121
, pp. 763-774
-
-
Cin, H.1
Meyer, C.2
Herr, R.3
Janzarik, W.G.4
Lambert, S.5
Jones, D.T.6
Jacob, K.7
Benner, A.8
Witt, H.9
Remke, M.10
Bender, S.11
Falkenstein, F.12
Van Anh, T.N.13
Olbrich, H.14
Von, D.A.15
Pekrun, A.16
Kulozik, A.E.17
Gnekow, A.18
Scheurlen, W.19
Witt, O.20
Omran, H.21
Jabado, N.22
Collins, V.P.23
Brummer, T.24
Marschalek, R.25
Lichter, P.26
Korshunov, A.27
Pfister, S.M.28
more..
-
36
-
-
84884700620
-
Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma. Genes Chromosomes
-
A.L. Feldman, G. Vasmatzis, Y.W. Asmann, J. Davila, S. Middha, B.W. Eckloff, S.H. Johnson, J.C. Porcher, S.M. Ansell, and A. Caride Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma. Genes Chromosomes Cancer 52 2013 1097 1102
-
(2013)
Cancer
, vol.52
, pp. 1097-1102
-
-
Feldman, A.L.1
Vasmatzis, G.2
Asmann, Y.W.3
Davila, J.4
Middha, S.5
Eckloff, B.W.6
Johnson, S.H.7
Porcher, J.C.8
Ansell, S.M.9
Caride, A.10
-
37
-
-
84884996623
-
The integrated landscape of driver genomic alterations in glioblastoma
-
V. Frattini, V. Trifonov, J.M. Chan, A. Castano, M. Lia, F. Abate, S.T. Keir, A.X. Ji, P. Zoppoli, F. Niola, C. Danussi, I. Dolgalev, P. Porrati, S. Pellegatta, A. Heguy, G. Gupta, D.J. Pisapia, P. Canoll, J.N. Bruce, R.E. McLendon, H. Yan, K. Aldape, G. Finocchiaro, T. Mikkelsen, G.G. Prive, D.D. Bigner, A. Lasorella, R. Rabadan, and A. Iavarone The integrated landscape of driver genomic alterations in glioblastoma Nat Genet 45 2013 1141 1149
-
(2013)
Nat Genet
, vol.45
, pp. 1141-1149
-
-
Frattini, V.1
Trifonov, V.2
Chan, J.M.3
Castano, A.4
Lia, M.5
Abate, F.6
Keir, S.T.7
Ji, A.X.8
Zoppoli, P.9
Niola, F.10
Danussi, C.11
Dolgalev, I.12
Porrati, P.13
Pellegatta, S.14
Heguy, A.15
Gupta, G.16
Pisapia, D.J.17
Canoll, P.18
Bruce, J.N.19
McLendon, R.E.20
Yan, H.21
Aldape, K.22
Finocchiaro, G.23
Mikkelsen, T.24
Prive, G.G.25
Bigner, D.D.26
Lasorella, A.27
Rabadan, R.28
Iavarone, A.29
more..
-
38
-
-
41349108673
-
The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1
-
C. Hidalgo-Curtis, A. Chase, M. Drachenberg, M.W. Roberts, J.Z. Finkelstein, S. Mould, D. Oscier, N.C. Cross, and F.H. Grand The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1 Genes Chromosomes Cancer 47 2008 379 385
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 379-385
-
-
Hidalgo-Curtis, C.1
Chase, A.2
Drachenberg, M.3
Roberts, M.W.4
Finkelstein, J.Z.5
Mould, S.6
Oscier, D.7
Cross, N.C.8
Grand, F.H.9
-
39
-
-
84882576021
-
CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma
-
S. Matsuura, K. Shinmura, T. Kamo, H. Igarashi, K. Maruyama, M. Tajima, H. Ogawa, M. Tanahashi, H. Niwa, K. Funai, T. Kohno, T. Suda, and H. Sugimura CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma Oncol Rep 30 2013 1675 1680
-
(2013)
Oncol Rep
, vol.30
, pp. 1675-1680
-
-
Matsuura, S.1
Shinmura, K.2
Kamo, T.3
Igarashi, H.4
Maruyama, K.5
Tajima, M.6
Ogawa, H.7
Tanahashi, M.8
Niwa, H.9
Funai, K.10
Kohno, T.11
Suda, T.12
Sugimura, H.13
-
40
-
-
0032942337
-
Fusion of a novel gene, ELKS, to RET due to translocation t(10;12)(q11;p13) in a papillary thyroid carcinoma
-
T. Nakata, Y. Kitamura, K. Shimizu, S. Tanaka, M. Fujimori, S. Yokoyama, K. Ito, and M. Emi Fusion of a novel gene, ELKS, to RET due to translocation t(10;12)(q11;p13) in a papillary thyroid carcinoma Genes Chromosomes Cancer 25 1999 97 103
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 97-103
-
-
Nakata, T.1
Kitamura, Y.2
Shimizu, K.3
Tanaka, S.4
Fujimori, M.5
Yokoyama, S.6
Ito, K.7
Emi, M.8
-
41
-
-
84913605660
-
Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay
-
Y.E. Nikiforov, S.E. Carty, S.I. Chiosea, C. Coyne, U. Duvvuri, R.L. Ferris, W.E. Gooding, S.P. Hodak, S.O. LeBeau, N.P. Ohori, R.R. Seethala, M.E. Tublin, L. Yip, and M.N. Nikiforova Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay Cancer 120 2014 3627 3634
-
(2014)
Cancer
, vol.120
, pp. 3627-3634
-
-
Nikiforov, Y.E.1
Carty, S.E.2
Chiosea, S.I.3
Coyne, C.4
Duvvuri, U.5
Ferris, R.L.6
Gooding, W.E.7
Hodak, S.P.8
LeBeau, S.O.9
Ohori, N.P.10
Seethala, R.R.11
Tublin, M.E.12
Yip, L.13
Nikiforova, M.N.14
-
42
-
-
77957667714
-
PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas
-
T. Ozawa, C.W. Brennan, L. Wang, M. Squatrito, T. Sasayama, M. Nakada, J.T. Huse, A. Pedraza, S. Utsuki, Y. Yasui, A. Tandon, E.I. Fomchenko, H. Oka, R.L. Levine, K. Fujii, M. Ladanyi, and E.C. Holland PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas Genes Dev 24 2010 2205 2218
-
(2010)
Genes Dev
, vol.24
, pp. 2205-2218
-
-
Ozawa, T.1
Brennan, C.W.2
Wang, L.3
Squatrito, M.4
Sasayama, T.5
Nakada, M.6
Huse, J.T.7
Pedraza, A.8
Utsuki, S.9
Yasui, Y.10
Tandon, A.11
Fomchenko, E.I.12
Oka, H.13
Levine, R.L.14
Fujii, K.15
Ladanyi, M.16
Holland, E.C.17
-
43
-
-
0034016275
-
Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: Biological, phenotypic, and clinical implications
-
H.M. Rabes, E.P. Demidchik, J.D. Sidorow, E. Lengfelder, C. Beimfohr, D. Hoelzel, and S. Klugbauer Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications Clin Cancer Res 6 2000 1093 1103
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1093-1103
-
-
Rabes, H.M.1
Demidchik, E.P.2
Sidorow, J.D.3
Lengfelder, E.4
Beimfohr, C.5
Hoelzel, D.6
Klugbauer, S.7
-
44
-
-
84868309107
-
The transcriptional landscape and mutational profile of lung adenocarcinoma
-
J.S. Seo, Y.S. Ju, W.C. Lee, J.Y. Shin, J.K. Lee, T. Bleazard, J. Lee, Y.J. Jung, J.O. Kim, J.Y. Shin, S.B. Yu, J. Kim, E.R. Lee, C.H. Kang, I.K. Park, H. Rhee, S.H. Lee, J.I. Kim, J.H. Kang, and Y.T. Kim The transcriptional landscape and mutational profile of lung adenocarcinoma Genome Res 22 2012 2109 2119
-
(2012)
Genome Res
, vol.22
, pp. 2109-2119
-
-
Seo, J.S.1
Ju, Y.S.2
Lee, W.C.3
Shin, J.Y.4
Lee, J.K.5
Bleazard, T.6
Lee, J.7
Jung, Y.J.8
Kim, J.O.9
Shin, J.Y.10
Yu, S.B.11
Kim, J.12
Lee, E.R.13
Kang, C.H.14
Park, I.K.15
Rhee, H.16
Lee, S.H.17
Kim, J.I.18
Kang, J.H.19
Kim, Y.T.20
more..
-
45
-
-
84871181092
-
Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions
-
Y. Suehara, M. Arcila, L. Wang, A. Hasanovic, D. Ang, T. Ito, Y. Kimura, A. Drilon, U. Guha, V. Rusch, M.G. Kris, M.F. Zakowski, N. Rizvi, R. Khanin, and M. Ladanyi Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions Clin Cancer Res 18 2012 6599 6608
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6599-6608
-
-
Suehara, Y.1
Arcila, M.2
Wang, L.3
Hasanovic, A.4
Ang, D.5
Ito, T.6
Kimura, Y.7
Drilon, A.8
Guha, U.9
Rusch, V.10
Kris, M.G.11
Zakowski, M.F.12
Rizvi, N.13
Khanin, R.14
Ladanyi, M.15
-
46
-
-
80255127234
-
Cutadapt removes adapter sequences from high-throughput sequencing reads
-
M. Martin Cutadapt removes adapter sequences from high-throughput sequencing reads EMBnet J 17 2011 10 12
-
(2011)
EMBnet J
, vol.17
, pp. 10-12
-
-
Martin, M.1
-
47
-
-
78650568308
-
SAMStat: Monitoring biases in next generation sequencing data
-
T. Lassmann, Y. Hayashizaki, and C.O. Daub SAMStat: monitoring biases in next generation sequencing data Bioinformatics 27 2011 130 131
-
(2011)
Bioinformatics
, vol.27
, pp. 130-131
-
-
Lassmann, T.1
Hayashizaki, Y.2
Daub, C.O.3
-
48
-
-
84929001104
-
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
-
The GTEx Consortium Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans Science 348 2015 648 660
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
-
49
-
-
84894066256
-
A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer
-
M.E. Lira, Y.L. Choi, S.M. Lim, S. Deng, D. Huang, M. Ozeck, J. Han, J.Y. Jeong, H.S. Shim, B.C. Cho, J. Kim, M.J. Ahn, and M. Mao A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer J Mol Diagn 16 2014 229 243
-
(2014)
J Mol Diagn
, vol.16
, pp. 229-243
-
-
Lira, M.E.1
Choi, Y.L.2
Lim, S.M.3
Deng, S.4
Huang, D.5
Ozeck, M.6
Han, J.7
Jeong, J.Y.8
Shim, H.S.9
Cho, B.C.10
Kim, J.11
Ahn, M.J.12
Mao, M.13
-
50
-
-
84938942340
-
An Efficient Method for Identifying Gene Fusions by Targeted RNA Sequencing from Fresh Frozen and FFPE Samples
-
J.A. Scolnick, M. Dimon, I.C. Wang, S.C. Huelga, and D.A. Amorese An Efficient Method for Identifying Gene Fusions by Targeted RNA Sequencing from Fresh Frozen and FFPE Samples PLoS One 10 2015 e0128916
-
(2015)
PLoS One
, vol.10
, pp. e0128916
-
-
Scolnick, J.A.1
Dimon, M.2
Wang, I.C.3
Huelga, S.C.4
Amorese, D.A.5
|