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Volumn 7, Issue , 2016, Pages

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHOLESTEROL; TRANSCRIPTION FACTOR 7 LIKE 2; PROTEIN BINDING; SOX10 PROTEIN, MOUSE; TCF7L2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX; ZBTB33 PROTEIN, MOUSE;

EID: 84960532324     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10883     Document Type: Article
Times cited : (122)

References (66)
  • 1
    • 0034646727 scopus 로고    scopus 로고
    • Origins of vertebrate success
    • Zalc, B. & Colman, D. R. Origins of vertebrate success. Science 288, 271-272 (2000).
    • (2000) Science , vol.288 , pp. 271-272
    • Zalc, B.1    Colman, D.R.2
  • 2
    • 84899946489 scopus 로고    scopus 로고
    • Astrocyte-encoded positional cues maintain sensorimotor circuit integrity
    • Molofsky, A. V., et al. Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature 509, 189-194 (2014).
    • (2014) Nature , vol.509 , pp. 189-194
    • Molofsky, A.V.1
  • 3
    • 84908108875 scopus 로고    scopus 로고
    • Motor skill learning requires active central myelination
    • McKenzie, I. A., et al. Motor skill learning requires active central myelination. Science 346, 318-322 (2014).
    • (2014) Science , vol.346 , pp. 318-322
    • McKenzie, I.A.1
  • 4
    • 84923226782 scopus 로고    scopus 로고
    • Dynamics and mechanisms of CNS myelination
    • Bercury, K. K. & Macklin, W. B. Dynamics and mechanisms of CNS myelination. Dev. Cell 32, 447-458 (2015).
    • (2015) Dev. Cell , vol.32 , pp. 447-458
    • Bercury, K.K.1    Macklin, W.B.2
  • 5
    • 84875185145 scopus 로고    scopus 로고
    • Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice
    • Han, X., et al. Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. Cell Stem Cell 12, 342-353 (2013).
    • (2013) Cell Stem Cell , vol.12 , pp. 342-353
    • Han, X.1
  • 6
    • 84887402039 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of oligodendrocyte development
    • Zuchero, J. B. & Barres, B. A. Intrinsic and extrinsic control of oligodendrocyte development. Curr. Opin. Neurobiol. 23, 914-920 (2013).
    • (2013) Curr. Opin. Neurobiol , vol.23 , pp. 914-920
    • Zuchero, J.B.1    Barres, B.A.2
  • 7
    • 84877873616 scopus 로고    scopus 로고
    • Coordinated control of oligodendrocyte development by extrinsic and intrinsic signaling cues
    • He, L. & Lu, Q. R. Coordinated control of oligodendrocyte development by extrinsic and intrinsic signaling cues. Neurosci. Bull. 29, 129-143 (2013).
    • (2013) Neurosci. Bull , vol.29 , pp. 129-143
    • He, L.1    Lu, Q.R.2
  • 8
    • 67649655942 scopus 로고    scopus 로고
    • Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
    • Fancy, S. P., et al. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev. 23, 1571-1585 (2009).
    • (2009) Genes Dev , vol.23 , pp. 1571-1585
    • Fancy, S.P.1
  • 9
    • 67649797866 scopus 로고    scopus 로고
    • HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction
    • Ye, F., et al. HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat. Neurosci. 12, 829-838 (2009).
    • (2009) Nat. Neurosci , vol.12 , pp. 829-838
    • Ye, F.1
  • 10
    • 84867787577 scopus 로고    scopus 로고
    • Pleiotrophin suppression of receptor protein tyrosine phosphatase-beta/zeta maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells
    • McClain, C. R., Sim, F. J. & Goldman, S. A. Pleiotrophin suppression of receptor protein tyrosine phosphatase-beta/zeta maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells. J. Neurosci. 32, 15066-15075 (2012).
    • (2012) J. Neurosci , vol.32 , pp. 15066-15075
    • McClain, C.R.1    Sim, F.J.2    Goldman, S.A.3
  • 11
    • 20444363086 scopus 로고    scopus 로고
    • Wnt signaling controls the timing of oligodendrocyte development in the spinal cord
    • Shimizu, T., et al. Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Dev. Biol. 282, 397-410 (2005).
    • (2005) Dev. Biol , vol.282 , pp. 397-410
    • Shimizu, T.1
  • 13
    • 79851503308 scopus 로고    scopus 로고
    • GSK3beta negatively regulates oligodendrocyte differentiation and myelination in vivo
    • Azim, K. & Butt, A. M. GSK3beta negatively regulates oligodendrocyte differentiation and myelination in vivo. Glia 59, 540-553 (2011).
    • (2011) Glia , vol.59 , pp. 540-553
    • Azim, K.1    Butt, A.M.2
  • 14
    • 79960764346 scopus 로고    scopus 로고
    • Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination
    • Fancy, S. P., et al. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat. Neurosci. 14, 1009-1016 (2011).
    • (2011) Nat. Neurosci , vol.14 , pp. 1009-1016
    • Fancy, S.P.1
  • 15
    • 84873651744 scopus 로고    scopus 로고
    • Adenomatous polyposis coli regulates oligodendroglial development
    • Lang, J., et al. Adenomatous polyposis coli regulates oligodendroglial development. J. Neurosci. 33, 3113-3130 (2013).
    • (2013) J. Neurosci , vol.33 , pp. 3113-3130
    • Lang, J.1
  • 16
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers, H. & Nusse, R. Wnt/beta-catenin signaling and disease. Cell 149, 1192-1205 (2012).
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 17
    • 84896596045 scopus 로고    scopus 로고
    • Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF
    • Schuijers, J., Mokry, M., Hatzis, P., Cuppen, E. & Clevers, H. Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. EMBO J. 33, 146-156 (2014).
    • (2014) EMBO J. , vol.33 , pp. 146-156
    • Schuijers, J.1    Mokry, M.2    Hatzis, P.3    Cuppen, E.4    Clevers, H.5
  • 18
    • 84925871779 scopus 로고    scopus 로고
    • The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/beta-catenin signaling
    • Hammond, E., et al. The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/beta-catenin signaling. J. Neurosci. 35, 5007-5022 (2015).
    • (2015) J. Neurosci , vol.35 , pp. 5007-5022
    • Hammond, E.1
  • 19
    • 33845355511 scopus 로고    scopus 로고
    • Diversity of LEF/TCF action in development and disease
    • Arce, L., Yokoyama, N. N. & Waterman, M. L. Diversity of LEF/TCF action in development and disease. Oncogene 25, 7492-7504 (2006).
    • (2006) Oncogene , vol.25 , pp. 7492-7504
    • Arce, L.1    Yokoyama, N.N.2    Waterman, M.L.3
  • 20
    • 84861372662 scopus 로고    scopus 로고
    • A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
    • Van Es, J. H., et al. A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal. Mol. Cell. Biol. 32, 1918-1927 (2012).
    • (2012) Mol. Cell. Biol , vol.32 , pp. 1918-1927
    • Van Es, J.H.1
  • 21
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek, V., et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat. Genet. 19, 379-383 (1998).
    • (1998) Nat. Genet , vol.19 , pp. 379-383
    • Korinek, V.1
  • 22
    • 13844276513 scopus 로고    scopus 로고
    • Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice
    • Xin, M., et al. Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice. J. Neurosci. 25, 1354-1365 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 1354-1365
    • Xin, M.1
  • 23
    • 84899066585 scopus 로고    scopus 로고
    • Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membrane-Anchored EGFP
    • Deng, Y., et al. Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membrane-Anchored EGFP. Genesis 52, 341-349 (2014).
    • (2014) Genesis , vol.52 , pp. 341-349
    • Deng, Y.1
  • 24
    • 0038583861 scopus 로고    scopus 로고
    • Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms
    • Hamilton, T. G., Klinghoffer, R. A., Corrin, P. D. & Soriano, P. Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol. Cell. Biol. 23, 4013-4025 (2003).
    • (2003) Mol. Cell. Biol , vol.23 , pp. 4013-4025
    • Hamilton, T.G.1    Klinghoffer, R.A.2    Corrin, P.D.3    Soriano, P.4
  • 25
    • 0037370361 scopus 로고    scopus 로고
    • Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
    • Lappe-Siefke, C., et al. Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat. Genet. 33, 366-374 (2003).
    • (2003) Nat. Genet , vol.33 , pp. 366-374
    • Lappe-Siefke, C.1
  • 26
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • Franklin, R. J. Why does remyelination fail in multiple sclerosis?. Nat. Rev. Neurosci. 3, 705-714 (2002).
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 705-714
    • Franklin, R.J.1
  • 27
    • 84872509787 scopus 로고    scopus 로고
    • Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation
    • Yu, Y., et al. Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell 152, 248-261 (2013).
    • (2013) Cell , vol.152 , pp. 248-261
    • Yu, Y.1
  • 28
    • 78650758676 scopus 로고    scopus 로고
    • Histone H3K27ac separates active from poised enhancers and predicts developmental state
    • Creyghton, M. P., et al. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl Acad. Sci. USA 107, 21931-21936 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 21931-21936
    • Creyghton, M.P.1
  • 29
    • 0037179716 scopus 로고    scopus 로고
    • Active genes are tri-methylated at K4 of histone H3.
    • Santos-Rosa, H., et al. Active genes are tri-methylated at K4 of histone H3. Nature 419, 407-411 (2002).
    • (2002) Nature , vol.419 , pp. 407-411
    • Santos-Rosa, H.1
  • 30
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz, S., et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1
  • 31
    • 42149183576 scopus 로고    scopus 로고
    • Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
    • Hatzis, P., et al. Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol. Cell. Biol. 28, 2732-2744 (2008).
    • (2008) Mol. Cell. Biol , vol.28 , pp. 2732-2744
    • Hatzis, P.1
  • 32
    • 84871596296 scopus 로고    scopus 로고
    • Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand
    • Boj, S. F., et al. Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell 151, 1595-1607 (2012).
    • (2012) Cell , vol.151 , pp. 1595-1607
    • Boj, S.F.1
  • 33
    • 65549141724 scopus 로고    scopus 로고
    • The interaction of xKaiso with xTcf3: A revised model for integration of epigenetic and Wnt signalling pathways
    • Ruzov, A., et al. The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways. Development 136, 723-727 (2009).
    • (2009) Development , vol.136 , pp. 723-727
    • Ruzov, A.1
  • 34
    • 19944425163 scopus 로고    scopus 로고
    • Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets
    • Park, J. I., et al. Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Dev. Cell 8, 843-854 (2005).
    • (2005) Dev. Cell , vol.8 , pp. 843-854
    • Park, J.I.1
  • 35
    • 0035394961 scopus 로고    scopus 로고
    • The p120 catenin partner Kaiso is a DNA methylationdependent transcriptional repressor
    • Prokhortchouk, A., et al. The p120 catenin partner Kaiso is a DNA methylationdependent transcriptional repressor. Genes Dev. 15, 1613-1618 (2001).
    • (2001) Genes Dev , vol.15 , pp. 1613-1618
    • Prokhortchouk, A.1
  • 36
    • 0029898417 scopus 로고    scopus 로고
    • Deletion of an aminoterminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein
    • Munemitsu, S., Albert, I., Rubinfeld, B. & Polakis, P. Deletion of an aminoterminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein. Mol. Cell. Biol. 16, 4088-4094 (1996).
    • (1996) Mol. Cell. Biol , vol.16 , pp. 4088-4094
    • Munemitsu, S.1    Albert, I.2    Rubinfeld, B.3    Polakis, P.4
  • 37
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
    • Korinek, V., et al. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 275, 1784-1787 (1997).
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1
  • 38
    • 0036793619 scopus 로고    scopus 로고
    • TGF-beta induces cell death in the oligodendroglial cell line OLI-neu
    • Schuster, N., et al. TGF-beta induces cell death in the oligodendroglial cell line OLI-neu. Glia 40, 95-108 (2002).
    • (2002) Glia , vol.40 , pp. 95-108
    • Schuster, N.1
  • 39
    • 32344449372 scopus 로고    scopus 로고
    • Kaiso-deficient mice show resistance to intestinal cancer
    • Prokhortchouk, A., et al. Kaiso-deficient mice show resistance to intestinal cancer. Mol. Cell. Biol. 26, 199-208 (2006).
    • (2006) Mol. Cell. Biol , vol.26 , pp. 199-208
    • Prokhortchouk, A.1
  • 40
    • 84864910444 scopus 로고    scopus 로고
    • Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve
    • Srinivasan, R., et al. Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve. Nucleic Acids Res. 40, 6449-6460 (2012).
    • (2012) Nucleic Acids Res , vol.40 , pp. 6449-6460
    • Srinivasan, R.1
  • 41
    • 0037080877 scopus 로고    scopus 로고
    • Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10.
    • Stolt, C. C., et al. Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 16, 165-170 (2002).
    • (2002) Genes Dev , vol.16 , pp. 165-170
    • Stolt, C.C.1
  • 42
    • 39849102805 scopus 로고    scopus 로고
    • Regulation of sterol synthesis in eukaryotes
    • Espenshade, P. J. & Hughes, A. L. Regulation of sterol synthesis in eukaryotes. Annu. Rev. Genet. 41, 401-427 (2007).
    • (2007) Annu. Rev. Genet , vol.41 , pp. 401-427
    • Espenshade, P.J.1    Hughes, A.L.2
  • 43
    • 1842473247 scopus 로고    scopus 로고
    • Impaired regulation of sterol regulatory element binding protein 2 in cholesterol gallstone-susceptible mice
    • Xu, G., Muller, O., Stange, E. F. & Fuchs, M. Impaired regulation of sterol regulatory element binding protein 2 in cholesterol gallstone-susceptible mice. Biochim. Biophys. Acta 1688, 274-279 (2004).
    • (2004) Biochim. Biophys. Acta 1688 , pp. 274-279
    • Xu, G.1    Muller, O.2    Stange, E.F.3    Fuchs, M.4
  • 44
    • 84894440490 scopus 로고    scopus 로고
    • Mutation of 3-hydroxy-3-methylglutaryl CoA synthase i reveals requirements for isoprenoid and cholesterol synthesis in oligodendrocyte migration arrest, axon wrapping, and myelin gene expression
    • Mathews, E. S., et al. Mutation of 3-hydroxy-3-methylglutaryl CoA synthase I reveals requirements for isoprenoid and cholesterol synthesis in oligodendrocyte migration arrest, axon wrapping, and myelin gene expression. J. Neurosci. 34, 3402-3412 (2014).
    • (2014) J. Neurosci , vol.34 , pp. 3402-3412
    • Mathews, E.S.1
  • 45
    • 20044370505 scopus 로고    scopus 로고
    • High cholesterol level is essential for myelin membrane growth
    • Saher, G., et al. High cholesterol level is essential for myelin membrane growth. Nat. Neurosci. 8, 468-475 (2005).
    • (2005) Nat. Neurosci , vol.8 , pp. 468-475
    • Saher, G.1
  • 46
    • 0028801536 scopus 로고
    • Cholesterol for synthesis of myelin is made locally, not imported into brain
    • Jurevics, H. & Morell, P. Cholesterol for synthesis of myelin is made locally, not imported into brain. J. Neurochem. 64, 895-901 (1995).
    • (1995) J. Neurochem , vol.64 , pp. 895-901
    • Jurevics, H.1    Morell, P.2
  • 47
    • 0014836183 scopus 로고
    • Inhibitors of cholesterol synthesis and myelin formation
    • Smith, M. E. & Hasinoff, C. M. Inhibitors of cholesterol synthesis and myelin formation. Lipids 5, 665-671 (1970).
    • (1970) Lipids , vol.5 , pp. 665-671
    • Smith, M.E.1    Hasinoff, C.M.2
  • 48
    • 84902440139 scopus 로고    scopus 로고
    • Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling
    • Dai, Z. M., et al. Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J. Neurosci. 34, 8467-8473 (2014).
    • (2014) J. Neurosci , vol.34 , pp. 8467-8473
    • Dai, Z.M.1
  • 49
    • 70349114302 scopus 로고    scopus 로고
    • A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development
    • Fu, H., et al. A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J. Neurosci. 29, 11399-11408 (2009).
    • (2009) J. Neurosci , vol.29 , pp. 11399-11408
    • Fu, H.1
  • 50
    • 34447262102 scopus 로고    scopus 로고
    • The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation
    • He, Y., et al. The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron 55, 217-230 (2007).
    • (2007) Neuron , vol.55 , pp. 217-230
    • He, Y.1
  • 51
    • 84938792312 scopus 로고    scopus 로고
    • Canonical Wnt signaling in the oligodendroglial lineage-puzzles remain
    • Guo, F., et al. Canonical Wnt signaling in the oligodendroglial lineage-puzzles remain. Glia 63, 1671-1693 (2015).
    • (2015) Glia , vol.63 , pp. 1671-1693
    • Guo, F.1
  • 52
    • 12344301501 scopus 로고    scopus 로고
    • Kaiso is a genome-wide repressor of transcription that is essential for amphibian development
    • Ruzov, A., et al. Kaiso is a genome-wide repressor of transcription that is essential for amphibian development. Development 131, 6185-6194 (2004).
    • (2004) Development , vol.131 , pp. 6185-6194
    • Ruzov, A.1
  • 53
    • 67649859499 scopus 로고    scopus 로고
    • Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression
    • Arce, L., Pate, K. T. & Waterman, M. L. Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. BMC Cancer 9, 159 (2009).
    • (2009) BMC Cancer , vol.9 , pp. 159
    • Arce, L.1    Pate, K.T.2    Waterman, M.L.3
  • 54
    • 84941172476 scopus 로고    scopus 로고
    • Differential Sox10 genomic occupancy in myelinating glia
    • Lopez-Anido, C., et al. Differential Sox10 genomic occupancy in myelinating glia. Glia 63, 1897-1914 (2015).
    • (2015) Glia , vol.63 , pp. 1897-1914
    • Lopez-Anido, C.1
  • 55
    • 84924320472 scopus 로고    scopus 로고
    • The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells
    • Norton, L., et al. The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells. Nucleic Acids Res. 42, 13646-13661 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. 13646-13661
    • Norton, L.1
  • 56
    • 84859907605 scopus 로고    scopus 로고
    • Tcf7l2 is tightly controlled during myelin formation
    • Fu, H., Kesari, S. & Cai, J. Tcf7l2 is tightly controlled during myelin formation. Cell. Mol. Neurobiol. 32, 345-352 (2012).
    • (2012) Cell. Mol. Neurobiol , vol.32 , pp. 345-352
    • Fu, H.1    Kesari, S.2    Cai, J.3
  • 57
    • 84882735248 scopus 로고    scopus 로고
    • Limited TCF7L2 expression in MS lesions
    • Lurbke, A., et al. Limited TCF7L2 expression in MS lesions. PLoS ONE 8, e72822 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e72822
    • Lurbke, A.1
  • 58
    • 84946031456 scopus 로고    scopus 로고
    • Meta-Analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes
    • Ng, M. C., et al. Meta-Analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 10, e1004517 (2014).
    • (2014) PLoS Genet , vol.10 , pp. e1004517
    • Ng, M.C.1
  • 59
    • 67249096093 scopus 로고    scopus 로고
    • Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
    • Shu, L., et al. Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function. Hum. Mol. Genet. 18, 2388-2399 (2009).
    • (2009) Hum. Mol. Genet , vol.18 , pp. 2388-2399
    • Shu, L.1
  • 60
    • 33750892139 scopus 로고    scopus 로고
    • Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
    • Saxena, R., et al. Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes 55, 2890-2895 (2006).
    • (2006) Diabetes , vol.55 , pp. 2890-2895
    • Saxena, R.1
  • 61
    • 84921931677 scopus 로고    scopus 로고
    • Reduced proliferation and survival of oligodendrocyte progenitor cells in ischemic white matter lesions due to type 2 diabetes
    • Yatomi, Y., et al. Reduced proliferation and survival of oligodendrocyte progenitor cells in ischemic white matter lesions due to type 2 diabetes. Neuroscience 289, 214-223 (2015).
    • (2015) Neuroscience , vol.289 , pp. 214-223
    • Yatomi, Y.1
  • 62
    • 33846815345 scopus 로고    scopus 로고
    • Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
    • Ligon, K. L., et al. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 53, 503-517 (2007).
    • (2007) Neuron , vol.53 , pp. 503-517
    • Ligon, K.L.1
  • 63
    • 0037023529 scopus 로고    scopus 로고
    • Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection
    • Lu, Q. R., et al. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 109, 75-86 (2002).
    • (2002) Cell , vol.109 , pp. 75-86
    • Lu, Q.R.1
  • 64
    • 34250186388 scopus 로고    scopus 로고
    • Isolation and culture of rat and mouse oligodendrocyte precursor cells
    • Chen, Y., et al. Isolation and culture of rat and mouse oligodendrocyte precursor cells. Nat. Protoc. 2, 1044-1051 (2007).
    • (2007) Nat. Protoc , vol.2 , pp. 1044-1051
    • Chen, Y.1
  • 65
    • 3242700771 scopus 로고    scopus 로고
    • NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes
    • Chan, J. R., et al. NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes. Neuron 43, 183-191 (2004).
    • (2004) Neuron , vol.43 , pp. 183-191
    • Chan, J.R.1
  • 66
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
    • (2012) Nature , vol.489 , pp. 57-74
    • Project Consortium, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.