The interaction of xKaiso with xTcf3: A revised model for integration of epigenetic and Wnt signalling pathways

Development

Volumn 136, Issue 5, 2009, Pages 723-727

  Ruzov, Alexey ^a   Hackett, Jamie A ^a   Prokhortchouk, Anna ^b   Reddington, James P ^a   Madej, Monika J ^a   Dunican, Donncha S ^a   Prokhortchouk, Egor ^b   Pennings, Sari ^c   Meehan, Richard R ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b INSTITUTE OF BIOENGINEERING   (Russian Federation)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cancer; Chromatin; DNA methylation; Kaiso; Siamois; TCF3

Indexed keywords

BETA CATENIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR XKAISO; TRANSCRIPTION FACTOR XTCF3; UNCLASSIFIED DRUG; DNA; REPRESSOR PROTEIN; T CELL FACTOR 3; T CELL FACTOR PROTEIN; WNT PROTEIN; XENOPUS PROTEIN; XKAISO PROTEIN, XENOPUS;

ANIMAL CELL; ARTICLE; BINDING SITE; CANCER GROWTH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA BINDING; EMBRYO; GENE ACTIVATION; GENE DELETION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE LOSS; GENE OVEREXPRESSION; GENE SEQUENCE; GENE SILENCING; GENE TARGETING; GENETIC EPIGENESIS; HIGH MOBILITY GROUP BOX DOMAIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; XENOPUS; ANIMAL; BIOLOGICAL MODEL; GENETICS; METABOLISM; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; DNA; EPIGENESIS, GENETIC; MICE; MODELS, BIOLOGICAL; MODELS, GENETIC; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; WNT PROTEINS; XENOPUS; XENOPUS PROTEINS;

EID: 65549141724     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.025577     Document Type: Article

References (14)

1. Clevers, H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127, 469-480.
2. Filion, G. J., Zhenilo, S., Salozhin, S., Yamada, D., Prokhortchouk, E. and Defossez, P. A. (2006). A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell. Biol. 26, 169-181.
3. Heasman, J. (2006). Patterning the early Xenopus embryo. Development 133, 1205-1217.
4. Houston, D. W., Kofron, M., Resnik, E., Langland, R., Destree, O., Wylie, C. and Heasman, J. (2002). Repression of organizer genes in dorsal and ventral Xenopus cells mediated by maternal XTcf3. Development 129, 4015-4025.
5. Kim, S. W., Park, J. I., Spring, C. M., Sater, A. K., Ji, H., Otchere, A. A., Daniel, J. M. and McCrea, P. D. (2004). Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin. Nat. Cell Biol. 6, 1212-1220.
6. Ohm, J. E., McGarvey, K. M., Yu, X., Cheng, L., Schuebel, K. E., Cope, L., Mohammad, H. P., Chen, W., Daniel, V. C., Yu, W. et al. (2007). A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat. Genet. 39, 237-242.
7. Park, J. I., Kim, S. W., Lyons, J. P., Ji, H., Nguyen, T. T., Cho, K., Barton, M. C., Deroo, T., Vleminckx, K., Moon, R. T. and McCrea, P. D. (2005). Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Dev. Cell 8, 843-854.
8. Prokhortchouk, A., Sansom, O., Selfridge, J., Caballero, I. M., Salozhin, S., Aithozhina, D., Cerchietti, L., Meng, F. G., Augenlicht, L. H., Mariadason, J. M. et al. (2006). Kaiso-deficient mice show resistance to intestinal cancer. Mol. Cell. Biol. 26, 199-208.
9. Roose, J., Molenaar, M., Peterson, J., Hurenkamp, J., Brantjes, H., Moerer, P., van de Wetering, M., Destree, O. and Clevers, H. (1998). The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature 395, 608-612.
10. Ruzov, A., Dunican, D. S., Prokhortchouk, A., Pennings, S., Stancheva, I., Prokhortchouk, E. and Meehan, R. R. (2004). Kaiso is a genome-wide repressor of transcription that is essential for amphibian development. Development 131, 6185-6194.
11. Ruzov, A., Savitskaya, E., Hackett, J. A., Reddington, J. P., Prokhortchouk, A., Madej, M. J., Chekanov, N., Li, M., Dunican, D. S., Prokhortchouk, E., Pennings, S. and Meehan, R. R. (2009). The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development. Development 136, 729-738.
12. Valenta, T., Lukas, J., Doubravska, L., Fafilek, B. and Korinek, V. (2006). HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. EMBO J. 25, 2326-2337.
13. Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H. and Moon, R. T. (2003). Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Curr. Biol. 13, 680-685.
14. Weber, A., Marquardt, J., Elzi, D., Forster, N., Starke, S., Glaum, A., Yamada, D., Defossez, P. A., Delrow, J., Eisenman, R. N., Christiansen, H. and Eilers, M. (2008). Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation. EMBO J. 27, 1563-1574.