메뉴 건너뛰기




Volumn 15, Issue 1, 2016, Pages 17-39

Efficacy and interaction of antioxidant supplements as adjuvant therapy in cancer treatment: A systematic review

Author keywords

Antioxidant; Cancer; Chemotherapy; Radiotherapy; Supplement; Vitamin

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ARGININE; ASCORBIC ACID; CAROTENOID; COUMARIN; CURCUMIN; ELLAGIC ACID; MELATONIN; POLYPHENOL DERIVATIVE; RETINOL; SELENIUM; THIOCTIC ACID; TOCOPHEROL; UBIDECARENONE; ZINC; POLYPHENOL; UBIQUINONE; FREE RADICAL; REACTIVE OXYGEN METABOLITE; VITAMIN;

EID: 84960438711     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735415610427     Document Type: Article
Times cited : (130)

References (130)
  • 1
    • 84897423109 scopus 로고    scopus 로고
    • Reduction of adverse effects by a mushroom product, active hexose correlated compound (AHCC) in patients with advanced cancer during chemotherapy: The significance of the levels of HHV-6 DNA in saliva as a surrogate biomarker during chemotherapy
    • Ito T, Urushima H, Sakaue M, et al. Reduction of adverse effects by a mushroom product, active hexose correlated compound (AHCC) in patients with advanced cancer during chemotherapy: the significance of the levels of HHV-6 DNA in saliva as a surrogate biomarker during chemotherapy. Nutr Cancer. 2014;66:377-382.
    • (2014) Nutr Cancer. , vol.66 , pp. 377-382
    • Ito, T.1    Urushima, H.2    Sakaue, M.3
  • 2
    • 18444374991 scopus 로고    scopus 로고
    • Nationwide survey on complementary and alternative medicine in cancer patients in Japan
    • Hyodo I, Amano N, Eguchi K, et al. Nationwide survey on complementary and alternative medicine in cancer patients in Japan. J Clin Oncol. 2005;23:2645-2654.
    • (2005) J Clin Oncol. , vol.23 , pp. 2645-2654
    • Hyodo, I.1    Amano, N.2    Eguchi, K.3
  • 3
    • 77956651323 scopus 로고    scopus 로고
    • The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development
    • Ziech D, Franco R, Georgakilas AG, et al. The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development. Chem Biol Interact. 2010;188:334-339.
    • (2010) Chem Biol Interact. , vol.188 , pp. 334-339
    • Ziech, D.1    Franco, R.2    Georgakilas, A.G.3
  • 4
    • 84870943008 scopus 로고    scopus 로고
    • Role of antioxidants in cancer therapy
    • Fuchs-Tarlovsky V. Role of antioxidants in cancer therapy. Nutrition. 2013;29(1):15-21.
    • (2013) Nutrition. , vol.29 , Issue.1 , pp. 15-21
    • Fuchs-Tarlovsky, V.1
  • 5
    • 0032697363 scopus 로고    scopus 로고
    • Antioxidants in cancer therapy: Their actions and interactions with oncologic therapies
    • Lamson DW, Brignall MS. Antioxidants in cancer therapy: their actions and interactions with oncologic therapies. Altern Med Rev. 1999;4:304-329.
    • (1999) Altern Med Rev. , vol.4 , pp. 304-329
    • Lamson, D.W.1    Brignall, M.S.2
  • 6
    • 0032805202 scopus 로고    scopus 로고
    • Possible interactions between dietary antioxidants and chemotherapy
    • discussion 1008, 1011-1002
    • Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology (Williston Park). 1999;13:1003-1008, discussion 1008, 1011-1002.
    • (1999) Oncology (Williston Park). , vol.13 , pp. 1003-1008
    • Labriola, D.1    Livingston, R.2
  • 7
    • 33847378451 scopus 로고    scopus 로고
    • Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
    • Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA. 2007;297:842-857.
    • (2007) JAMA , vol.297 , pp. 842-857
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 8
    • 34547197625 scopus 로고    scopus 로고
    • Impact of antioxidant supplementation on chemotherapeutic efficacy: A systematic review of the evidence from randomized controlled trials
    • Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer Treat Rev. 2007;33:407-418.
    • (2007) Cancer Treat Rev. , vol.33 , pp. 407-418
    • Block, K.I.1    Koch, A.C.2    Mead, M.N.3    Tothy, P.K.4    Newman, R.A.5    Gyllenhaal, C.6
  • 9
    • 84961800083 scopus 로고    scopus 로고
    • National Cancer Institute. Bethesda, MD: National Cancer Institute. Accessed September 28
    • National Cancer Institute. Antioxidants and Cancer Prevention: Fact Sheet. Bethesda, MD: National Cancer Institute. Accessed September 28, 2015. Website. http://www.cancer.gov/about-cancer/causes-prevention/risk/diet/antioxidants-fact-sheet
    • (2015) Antioxidants and Cancer Prevention: Fact Sheet
  • 11
    • 0026079081 scopus 로고
    • Nutritional approach to cancer prevention with emphasis on vitamins, antioxidants, and carotenoids
    • Weisburger JH. Nutritional approach to cancer prevention with emphasis on vitamins, antioxidants, and carotenoids. Am J Clin Nutr. 1991;53(1, suppl):S226-S237.
    • (1991) Am J Clin Nutr. , vol.53 , Issue.1 , pp. S226-S237
    • Weisburger, J.H.1
  • 12
    • 34447295618 scopus 로고    scopus 로고
    • Treatment of hypertension with nutraceuticals, vitamins, antioxidants and minerals
    • Houston MC. Treatment of hypertension with nutraceuticals, vitamins, antioxidants and minerals. Expert Rev Cardiovasc Ther. 2007;5:681-691.
    • (2007) Expert Rev Cardiovasc Ther. , vol.5 , pp. 681-691
    • Houston, M.C.1
  • 14
    • 0027226323 scopus 로고
    • The essential functions of coenzyme Q
    • Crane FL, Sun IL, Sun EE. The essential functions of coenzyme Q. Clin Investig. 1993;71(8, suppl):S55-S59.
    • (1993) Clin Investig. , vol.71 , Issue.8 , pp. S55-S59
    • Crane, F.L.1    Sun, I.L.2    Sun, E.E.3
  • 15
    • 0033055268 scopus 로고    scopus 로고
    • Critical aspects of the antioxidant function of coenzyme Q in biomembranes
    • Nohl H, Gille L, Kozlov AV. Critical aspects of the antioxidant function of coenzyme Q in biomembranes. Biofactors. 1999;9:155-161.
    • (1999) Biofactors. , vol.9 , pp. 155-161
    • Nohl, H.1    Gille, L.2    Kozlov, A.V.3
  • 16
    • 43449128829 scopus 로고    scopus 로고
    • Anti-angiogenic potential of coenzyme Q10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy
    • Premkumar VG, Yuvaraj S, Sathish S, Shanthi P, Sachdanandam P. Anti-angiogenic potential of coenzyme Q10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy. Vascul Pharmacol. 2008;48:191-201.
    • (2008) Vascul Pharmacol. , vol.48 , pp. 191-201
    • Premkumar, V.G.1    Yuvaraj, S.2    Sathish, S.3    Shanthi, P.4    Sachdanandam, P.5
  • 18
    • 0028618817 scopus 로고
    • Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure: CoQ10 Drug Surveillance Investigators
    • Baggio E, Gandini R, Plancher AC, Passeri M, Carmosino G. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure: CoQ10 Drug Surveillance Investigators. Mol Aspects Med. 1994;15(suppl):S287-S294.
    • (1994) Mol Aspects Med. , vol.15 , pp. S287-S294
    • Baggio, E.1    Gandini, R.2    Plancher, A.C.3    Passeri, M.4    Carmosino, G.5
  • 19
    • 84870457971 scopus 로고    scopus 로고
    • Lack of effect of coenzyme q10 on doxorubicin cytotoxicity in breast cancer cell cultures
    • Greenlee H, Shaw J, Lau YK, Naini A, Maurer M. Lack of effect of coenzyme q10 on doxorubicin cytotoxicity in breast cancer cell cultures. Integr Cancer Ther. 2012;11:243-250.
    • (2012) Integr Cancer Ther. , vol.11 , pp. 243-250
    • Greenlee, H.1    Shaw, J.2    Lau, Y.K.3    Naini, A.4    Maurer, M.5
  • 20
    • 19544371393 scopus 로고    scopus 로고
    • Coenzyme q10 for prevention of anthracyclineinduced cardiotoxicity
    • Conklin KA. Coenzyme q10 for prevention of anthracyclineinduced cardiotoxicity. Integr Cancer Ther. 2005;4:110-130.
    • (2005) Integr Cancer Ther. , vol.4 , pp. 110-130
    • Conklin, K.A.1
  • 22
  • 23
    • 34249091108 scopus 로고    scopus 로고
    • Recombinant interferon alpha-2b and coenzyme Q10 as a postsurgical adjuvant therapy for melanoma: A 3-year trial with recombinant interferon-alpha and 5-year follow-up
    • Rusciani L, Proietti I, Paradisi A, et al. Recombinant interferon alpha-2b and coenzyme Q10 as a postsurgical adjuvant therapy for melanoma: a 3-year trial with recombinant interferon-alpha and 5-year follow-up. Melanoma Res. 2007;17:177-183.
    • (2007) Melanoma Res. , vol.17 , pp. 177-183
    • Rusciani, L.1    Proietti, I.2    Paradisi, A.3
  • 24
    • 0021058948 scopus 로고
    • Protective effects of coenzyme Q10 on the adverse reactions of anthracycline antibiotics: Using double blind method- with special reference to hair loss
    • Akihama T, Nakamoto Y, Shindo T, Nakayama Y, Miura A. Protective effects of coenzyme Q10 on the adverse reactions of anthracycline antibiotics: using double blind method- with special reference to hair loss. Gan To Kagaku Ryoho. 1983;10:2125-2129.
    • (1983) Gan to Kagaku Ryoho. , vol.10 , pp. 2125-2129
    • Akihama, T.1    Nakamoto, Y.2    Shindo, T.3    Nakayama, Y.4    Miura, A.5
  • 25
    • 0021337050 scopus 로고
    • Protective effect of coenzyme Q10 in cardiotoxicity induced by adriamycin
    • Okuma K, Furuta I, Ota K. Protective effect of coenzyme Q10 in cardiotoxicity induced by adriamycin. Gan To Kagaku Ryoho. 1984;11:502-508.
    • (1984) Gan to Kagaku Ryoho. , vol.11 , pp. 502-508
    • Okuma, K.1    Furuta, I.2    Ota, K.3
  • 26
    • 0020046364 scopus 로고
    • Protective effect of CoQ 10 administration on cardial toxicity in FAC therapy
    • Takimoto M, Sakurai T, Kodama K, et al. Protective effect of CoQ 10 administration on cardial toxicity in FAC therapy. Gan To Kagaku Ryoho. 1982;9:116-121.
    • (1982) Gan to Kagaku Ryoho. , vol.9 , pp. 116-121
    • Takimoto, M.1    Sakurai, T.2    Kodama, K.3
  • 27
    • 0028652328 scopus 로고
    • Protective effect of coenzyme Q10 on anthracyclines cardiotoxicity: Control study in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma
    • Iarussi D, Auricchio U, Agretto A, et al. Protective effect of coenzyme Q10 on anthracyclines cardiotoxicity: control study in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma. Mol Aspects Med. 1994;15(suppl): S207-S212.
    • (1994) Mol Aspects Med. , vol.15 , pp. S207-S212
    • Iarussi, D.1    Auricchio, U.2    Agretto, A.3
  • 28
    • 84879326542 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer
    • Lesser GJ, Case D, Stark N, et al. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer. J Support Oncol. 2013;11(1): 31-42.
    • (2013) J Support Oncol. , vol.11 , Issue.1 , pp. 31-42
    • Lesser, G.J.1    Case, D.2    Stark, N.3
  • 29
  • 30
    • 0021227758 scopus 로고
    • Investigation of the preventive effect of CoQ10 against the side-effects of anthracycline antineoplastic agents
    • Tsubaki K, Horiuchi A, Kitani T, et al. Investigation of the preventive effect of CoQ10 against the side-effects of anthracycline antineoplastic agents. Gan To Kagaku Ryoho. 1984;11:1420-1427.
    • (1984) Gan to Kagaku Ryoho. , vol.11 , pp. 1420-1427
    • Tsubaki, K.1    Horiuchi, A.2    Kitani, T.3
  • 31
    • 0030071519 scopus 로고    scopus 로고
    • Alltrans- retinoic acid inhibits growth of human pancreatic cancer cell lines
    • Bold RJ, Ishizuka J, Townsend CM Jr, Thompson JC. Alltrans- retinoic acid inhibits growth of human pancreatic cancer cell lines. Pancreas. 1996;12:189-195.
    • (1996) Pancreas. , vol.12 , pp. 189-195
    • Bold, R.J.1    Ishizuka, J.2    Townsend, C.M.3    Thompson, J.C.4
  • 32
    • 0025761705 scopus 로고
    • Antiproliferative activity of retinoids, interferon alpha and their combination in five human transformed cell lines
    • Frey JR, Peck R, Bollag W. Antiproliferative activity of retinoids, interferon alpha and their combination in five human transformed cell lines. Cancer Lett. 1991;57:223-227.
    • (1991) Cancer Lett. , vol.57 , pp. 223-227
    • Frey, J.R.1    Peck, R.2    Bollag, W.3
  • 33
    • 0025339810 scopus 로고
    • Vitamin A protects the small intestine from methotrexate-induced damage in rats
    • Tsurui K, Kosakai Y, Horie T, Awazu S. Vitamin A protects the small intestine from methotrexate-induced damage in rats. J Pharmacol Exp Ther. 1990;253:1278-1284.
    • (1990) J Pharmacol Exp Ther. , vol.253 , pp. 1278-1284
    • Tsurui, K.1    Kosakai, Y.2    Horie, T.3    Awazu, S.4
  • 34
    • 0022371423 scopus 로고
    • Vitamin A augmentation of the effects of chemotherapy in metastatic breast cancers after menopause: Randomized trial in 100 patients
    • Israel L, Hajji O, Grefft-Alami A, et al. Vitamin A augmentation of the effects of chemotherapy in metastatic breast cancers after menopause: randomized trial in 100 patients. Ann Med Interne (Paris). 1985;136:551-554.
    • (1985) Ann Med Interne (Paris). , vol.136 , pp. 551-554
    • Israel, L.1    Hajji, O.2    Grefft-Alami, A.3
  • 36
    • 0029099722 scopus 로고
    • Effects of Vitamin A on survival in patients with chronic myelogenous leukemia: A SWOG randomized trial
    • Meyskens FL Jr, Kopecky KJ, Appelbaum FR, Balcerzak SP, Samlowski W, Hynes H. Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial. Leuk Res. 1995;19:605-612.
    • (1995) Leuk Res. , vol.19 , pp. 605-612
    • Meyskens, F.L.1    Kopecky, K.J.2    Appelbaum, F.R.3    Balcerzak, S.P.4    Samlowski, W.5    Hynes, H.6
  • 37
  • 39
    • 0036176842 scopus 로고    scopus 로고
    • Nutritional approaches to radioprotection: Vitamin E
    • Kumar KS, Srinivasan V, Toles R, Jobe L, Seed TM. Nutritional approaches to radioprotection: vitamin E. Mil Med. 2002;167(2, suppl):S57-S59.
    • (2002) Mil Med. , vol.167 , Issue.2 , pp. S57-S59
    • Kumar, K.S.1    Srinivasan, V.2    Toles, R.3    Jobe, L.4    Seed, T.M.5
  • 40
    • 24944500925 scopus 로고    scopus 로고
    • Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients
    • Bairati I, Meyer F, Gelinas M, et al. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. J Clin Oncol. 2005;23:5805-5813.
    • (2005) J Clin Oncol. , vol.23 , pp. 5805-5813
    • Bairati, I.1    Meyer, F.2    Gelinas, M.3
  • 41
    • 20244384114 scopus 로고    scopus 로고
    • Chemotherapy alone vs. Chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer
    • Pathak AK, Bhutani M, Guleria R, et al. Chemotherapy alone vs. chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer. J Am Coll Nutr. 2005;24:16-21.
    • (2005) J Am Coll Nutr. , vol.24 , pp. 16-21
    • Pathak, A.K.1    Bhutani, M.2    Guleria, R.3
  • 42
    • 39649110870 scopus 로고    scopus 로고
    • Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: A randomized trial among head and neck cancer patients
    • Meyer F, Bairati I, Fortin A, et al. Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: a randomized trial among head and neck cancer patients. Int J Cancer. 2008;122:1679-1683.
    • (2008) Int J Cancer. , vol.122 , pp. 1679-1683
    • Meyer, F.1    Bairati, I.2    Fortin, A.3
  • 44
    • 84863408900 scopus 로고    scopus 로고
    • Effect of vitamins C and e on antioxidant status of breast-cancer patients undergoing chemotherapy
    • Suhail N, Bilal N, Khan HY, et al. Effect of vitamins C and E on antioxidant status of breast-cancer patients undergoing chemotherapy. J Clin Pharm Ther. 2012;37:22-26.
    • (2012) J Clin Pharm Ther. , vol.37 , pp. 22-26
    • Suhail, N.1    Bilal, N.2    Khan, H.Y.3
  • 45
    • 1842421979 scopus 로고    scopus 로고
    • Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: A double-blind randomized trial
    • Ferreira PR, Fleck JF, Diehl A, et al. Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: a double-blind randomized trial. Head Neck. 2004;26:313-321.
    • (2004) Head Neck. , vol.26 , pp. 313-321
    • Ferreira, P.R.1    Fleck, J.F.2    Diehl, A.3
  • 46
    • 0037366026 scopus 로고    scopus 로고
    • Neuroprotective effect of Vitamin E supplementation in patients treated with cisplatin chemotherapy
    • Pace A, Savarese A, Picardo M, et al. Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. J Clin Oncol. 2003;21:927-931.
    • (2003) J Clin Oncol. , vol.21 , pp. 927-931
    • Pace, A.1    Savarese, A.2    Picardo, M.3
  • 47
    • 83255166592 scopus 로고    scopus 로고
    • The use of Vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: Results of a randomized phase III clinical trial
    • Kottschade LA, Sloan JA, Mazurczak MA, et al. The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase III clinical trial. Support Care Cancer. 2011;19:1769-1777.
    • (2011) Support Care Cancer. , vol.19 , pp. 1769-1777
    • Kottschade, L.A.1    Sloan, J.A.2    Mazurczak, M.A.3
  • 48
    • 33748206400 scopus 로고    scopus 로고
    • Preventing paclitaxel- induced peripheral neuropathy: A phase II trial of Vitamin E supplementation
    • Argyriou AA, Chroni E, Koutras A, et al. Preventing paclitaxel- induced peripheral neuropathy: a phase II trial of vitamin E supplementation. J Pain Symptom Manage. 2006;32: 237-244.
    • (2006) J Pain Symptom Manage. , vol.32 , pp. 237-244
    • Argyriou, A.A.1    Chroni, E.2    Koutras, A.3
  • 49
    • 33845454129 scopus 로고    scopus 로고
    • A randomized controlled trial evaluating the efficacy and safety of Vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: Final results
    • Argyriou AA, Chroni E, Koutras A, et al. A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results. Support Care Cancer. 2006;14:1134-1140.
    • (2006) Support Care Cancer. , vol.14 , pp. 1134-1140
    • Argyriou, A.A.1    Chroni, E.2    Koutras, A.3
  • 50
    • 77649243226 scopus 로고    scopus 로고
    • Vitamin E neuroprotection for cisplatin neuropathy: A randomized, placebo-controlled trial
    • Pace A, Giannarelli D, Galie E, et al. Vitamin E neuroprotection for cisplatin neuropathy: a randomized, placebo-controlled trial. Neurology. 2010;74:762-766.
    • (2010) Neurology. , vol.74 , pp. 762-766
    • Pace, A.1    Giannarelli, D.2    Galie, E.3
  • 52
    • 52449117453 scopus 로고    scopus 로고
    • Effects of radiation and alphatocopherol on saliva flow rate, amylase activity, total protein and electrolyte levels in oral cavity cancer
    • Chitra S, Shyamala Devi CS. Effects of radiation and alphatocopherol on saliva flow rate, amylase activity, total protein and electrolyte levels in oral cavity cancer. Indian J Dent Res. 2008;19:213-218.
    • (2008) Indian J Dent Res. , vol.19 , pp. 213-218
    • Chitra, S.1    Shyamala Devi, C.S.2
  • 54
    • 0027277108 scopus 로고
    • A double- blind, randomized, prospective trial to evaluate topical Vitamin C solution for the prevention of radiation dermatitis: CNS Cancer Consortium
    • Halperin EC, Gaspar L, George S, Darr D, Pinnell S. A double- blind, randomized, prospective trial to evaluate topical vitamin C solution for the prevention of radiation dermatitis: CNS Cancer Consortium. Int J Radiat Oncol Biol Phys. 1993;26:413-416.
    • (1993) Int J Radiat Oncol Biol Phys. , vol.26 , pp. 413-416
    • Halperin, E.C.1    Gaspar, L.2    George, S.3    Darr, D.4    Pinnell, S.5
  • 55
    • 24344434734 scopus 로고    scopus 로고
    • Plasma carotenoids as biomarkers of intake of fruits and vegetables: Individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    • Al-Delaimy WK, Ferrari P, Slimani N, et al. Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Clin Nutr. 2005;59:1387-1396.
    • (2005) Eur J Clin Nutr. , vol.59 , pp. 1387-1396
    • Al-Delaimy, W.K.1    Ferrari, P.2    Slimani, N.3
  • 56
    • 10044247436 scopus 로고    scopus 로고
    • Dietary carotenoids and genetic instability modify bladder cancer risk
    • Schabath MB, Grossman HB, Delclos GL, et al. Dietary carotenoids and genetic instability modify bladder cancer risk. J Nutr. 2004;134:3362-3369.
    • (2004) J Nutr. , vol.134 , pp. 3362-3369
    • Schabath, M.B.1    Grossman, H.B.2    Delclos, G.L.3
  • 57
    • 85047689688 scopus 로고    scopus 로고
    • Lycopene: A novel drug therapy in hormone refractory metastatic prostate cancer
    • Ansari MS, Gupta NP. Lycopene: a novel drug therapy in hormone refractory metastatic prostate cancer. Urol Oncol. 2004;22:415-420.
    • (2004) Urol Oncol. , vol.22 , pp. 415-420
    • Ansari, M.S.1    Gupta, N.P.2
  • 58
    • 0035836078 scopus 로고    scopus 로고
    • Effects of a lycopene-rich diet on spontaneous and benzo[a]pyrene-induced mutagenesis in prostate, colon and lungs of the lacZ mouse
    • Guttenplan JB, Chen M, Kosinska W, Thompson S, Zhao Z, Cohen LA. Effects of a lycopene-rich diet on spontaneous and benzo[a]pyrene-induced mutagenesis in prostate, colon and lungs of the lacZ mouse. Cancer Lett. 2001;164:1-6.
    • (2001) Cancer Lett. , vol.164 , pp. 1-6
    • Guttenplan, J.B.1    Chen, M.2    Kosinska, W.3    Thompson, S.4    Zhao, Z.5    Cohen, L.A.6
  • 59
    • 84879692789 scopus 로고    scopus 로고
    • Antioxidant supplementation has a positive effect on oxidative stress and hematological toxicity during oncology treatment in cervical cancer patients
    • Fuchs-Tarlovsky V, Rivera MA, Altamirano KA, Lopez-Alvarenga JC, Ceballos-Reyes GM. Antioxidant supplementation has a positive effect on oxidative stress and hematological toxicity during oncology treatment in cervical cancer patients. Support Care Cancer. 2013;21:1359-1363.
    • (2013) Support Care Cancer. , vol.21 , pp. 1359-1363
    • Fuchs-Tarlovsky, V.1    Rivera, M.A.2    Altamirano, K.A.3    Lopez-Alvarenga, J.C.4    Ceballos-Reyes, G.M.5
  • 60
    • 0028270330 scopus 로고
    • Hematopoietic rescue via T-cell-dependent, endogenous granulocyte-macrophage colony-stimulating factor induced by the pineal neurohormone melatonin in tumor-bearing mice
    • Maestroni GJ, Covacci V, Conti A. Hematopoietic rescue via T-cell-dependent, endogenous granulocyte-macrophage colony-stimulating factor induced by the pineal neurohormone melatonin in tumor-bearing mice. Cancer Res. 1994;54: 2429-2432.
    • (1994) Cancer Res. , vol.54 , pp. 2429-2432
    • Maestroni, G.J.1    Covacci, V.2    Conti, A.3
  • 61
    • 0032903822 scopus 로고    scopus 로고
    • Double-blind randomized study on the myeloprotective effect of melatonin in combination with carboplatin and etoposide in advanced lung cancer
    • Ghielmini M, Pagani O, de Jong J, et al. Double-blind randomized study on the myeloprotective effect of melatonin in combination with carboplatin and etoposide in advanced lung cancer. Br J Cancer. 1999;80:1058-1061.
    • (1999) Br J Cancer. , vol.80 , pp. 1058-1061
    • Ghielmini, M.1    Pagani, O.2    De Jong, J.3
  • 62
    • 0031021914 scopus 로고    scopus 로고
    • Melatonin in humans
    • Brzezinski A. Melatonin in humans. N Engl J Med. 1997;336:186-195.
    • (1997) N Engl J Med. , vol.336 , pp. 186-195
    • Brzezinski, A.1
  • 63
    • 34249739700 scopus 로고    scopus 로고
    • Biochemotherapy with standard chemotherapies plus the pineal hormone melatonin in the treatment of advanced solid neoplasms
    • Lissoni P. Biochemotherapy with standard chemotherapies plus the pineal hormone melatonin in the treatment of advanced solid neoplasms. Pathol Biol (Paris). 2007;55: 201-204.
    • (2007) Pathol Biol (Paris). , vol.55 , pp. 201-204
    • Lissoni, P.1
  • 64
    • 0038346728 scopus 로고    scopus 로고
    • Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: A randomized trial
    • Lissoni P, Chilelli M, Villa S, Cerizza L, Tancini G. Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: a randomized trial. J Pineal Res. 2003;35:12-15.
    • (2003) J Pineal Res. , vol.35 , pp. 12-15
    • Lissoni, P.1    Chilelli, M.2    Villa, S.3    Cerizza, L.4    Tancini, G.5
  • 65
    • 0030974891 scopus 로고    scopus 로고
    • Treatment of cancer chemotherapy- induced toxicity with the pineal hormone melatonin
    • Lissoni P, Tancini G, Barni S, et al. Treatment of cancer chemotherapy- induced toxicity with the pineal hormone melatonin. Support Care Cancer. 1997;5:126-129.
    • (1997) Support Care Cancer. , vol.5 , pp. 126-129
    • Lissoni, P.1    Tancini, G.2    Barni, S.3
  • 66
    • 0033383164 scopus 로고    scopus 로고
    • Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status
    • Lissoni P, Barni S, Mandala M, et al. Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status. Eur J Cancer. 1999;35:1688-1692.
    • (1999) Eur J Cancer. , vol.35 , pp. 1688-1692
    • Lissoni, P.1    Barni, S.2    Mandala, M.3
  • 67
    • 0037524440 scopus 로고    scopus 로고
    • Biomodulation of cancer chemotherapy for metastatic colorectal cancer: A randomized study of weekly low-dose irinotecan alone versus irinotecan plus the oncostatic pineal hormone melatonin in metastatic colorectal cancer patients progressing on 5-fluorouracil-containing combinations
    • Cerea G, Vaghi M, Ardizzoia A, et al. Biomodulation of cancer chemotherapy for metastatic colorectal cancer: a randomized study of weekly low-dose irinotecan alone versus irinotecan plus the oncostatic pineal hormone melatonin in metastatic colorectal cancer patients progressing on 5-fluorouracil-containing combinations. Anticancer Res. 2003;23:1951-1954.
    • (2003) Anticancer Res. , vol.23 , pp. 1951-1954
    • Cerea, G.1    Vaghi, M.2    Ardizzoia, A.3
  • 68
    • 34249716813 scopus 로고    scopus 로고
    • Biochemotherapy with immunomodulating pineal hormones other than melatonin: 5-methoxytryptamine as a new oncostatic pineal agent
    • Lissoni P. Biochemotherapy with immunomodulating pineal hormones other than melatonin: 5-methoxytryptamine as a new oncostatic pineal agent. Pathol Biol (Paris). 2007;55: 198-200.
    • (2007) Pathol Biol (Paris). , vol.55 , pp. 198-200
    • Lissoni, P.1
  • 69
    • 0031202122 scopus 로고    scopus 로고
    • A randomized study of chemotherapy with cisplatin plus etoposide versus chemoendocrine therapy with cisplatin, etoposide and the pineal hormone melatonin as a first-line treatment of advanced non-small cell lung cancer patients in a poor clinical state
    • Lissoni P, Paolorossi F, Ardizzoia A, et al. A randomized study of chemotherapy with cisplatin plus etoposide versus chemoendocrine therapy with cisplatin, etoposide and the pineal hormone melatonin as a first-line treatment of advanced non-small cell lung cancer patients in a poor clinical state. J Pineal Res. 1997;23:15-19.
    • (1997) J Pineal Res. , vol.23 , pp. 15-19
    • Lissoni, P.1    Paolorossi, F.2    Ardizzoia, A.3
  • 71
    • 84891669984 scopus 로고    scopus 로고
    • Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment
    • Ibrahimpasic K. Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. Med Arch. 2013;67:7-9.
    • (2013) Med Arch. , vol.67 , pp. 7-9
    • Ibrahimpasic, K.1
  • 72
    • 84897559344 scopus 로고    scopus 로고
    • Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: A randomized, double-blind, placebo-controlled trial
    • Guo Y, Jones D, Palmer JL, et al. Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled trial. Support Care Cancer. 2014;22:1223-1231.
    • (2014) Support Care Cancer. , vol.22 , pp. 1223-1231
    • Guo, Y.1    Jones, D.2    Palmer, J.L.3
  • 73
    • 84902077510 scopus 로고    scopus 로고
    • Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines
    • Kim J, Cho HJ, Sagong B, et al. Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines. Biochem Biophys Res Commun. 2014;449:183-189.
    • (2014) Biochem Biophys Res Commun. , vol.449 , pp. 183-189
    • Kim, J.1    Cho, H.J.2    Sagong, B.3
  • 74
    • 33746073732 scopus 로고    scopus 로고
    • Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer
    • Pantuck AJ, Leppert JT, Zomorodian N, et al. Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Clin Cancer Res. 2006;12:4018-4026.
    • (2006) Clin Cancer Res. , vol.12 , pp. 4018-4026
    • Pantuck, A.J.1    Leppert, J.T.2    Zomorodian, N.3
  • 75
    • 63149091751 scopus 로고    scopus 로고
    • A review of the antioxidant mechanisms of polyphenol compounds related to iron binding
    • Perron NR, Brumaghim JL. A review of the antioxidant mechanisms of polyphenol compounds related to iron binding. Cell Biochem Biophys. 2009;53:75-100.
    • (2009) Cell Biochem Biophys. , vol.53 , pp. 75-100
    • Perron, N.R.1    Brumaghim, J.L.2
  • 76
    • 52449135055 scopus 로고    scopus 로고
    • Efficiency of ellagic acid and arbutin in melasma: A randomized, prospective, open-label study
    • Ertam I, Mutlu B, Unal I, Alper S, Kivcak B, Ozer O. Efficiency of ellagic acid and arbutin in melasma: a randomized, prospective, open-label study. J Dermatol. 2008;35:570-574.
    • (2008) J Dermatol. , vol.35 , pp. 570-574
    • Ertam, I.1    Mutlu, B.2    Unal, I.3    Alper, S.4    Kivcak, B.5    Ozer, O.6
  • 77
    • 0036129447 scopus 로고    scopus 로고
    • Constituents and their antioxidative effects in eucalyptus leaf extract used as a natural food additive
    • Amakura Y, Umino Y, Tsuji S, et al. Constituents and their antioxidative effects in eucalyptus leaf extract used as a natural food additive. Food Chem. 2002;77:47-56.
    • (2002) Food Chem. , vol.77 , pp. 47-56
    • Amakura, Y.1    Umino, Y.2    Tsuji, S.3
  • 78
    • 0032998840 scopus 로고    scopus 로고
    • Determining efficacy of cancer chemopreventive agents using a cell-free system concomitant with DNA adduction
    • Smith WA, Gupta RC. Determining efficacy of cancer chemopreventive agents using a cell-free system concomitant with DNA adduction. Mutat Res. 1999;425:143-152.
    • (1999) Mutat Res. , vol.425 , pp. 143-152
    • Smith, W.A.1    Gupta, R.C.2
  • 79
    • 14844355240 scopus 로고    scopus 로고
    • Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate
    • discussion 454-455
    • Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate. Eur Urol. 2005;47:449-454, discussion 454-455.
    • (2005) Eur Urol. , vol.47 , pp. 449-454
    • Falsaperla, M.1    Morgia, G.2    Tartarone, A.3    Ardito, R.4    Romano, G.5
  • 80
    • 84896495055 scopus 로고    scopus 로고
    • Antioxidant and intestinal anti-inflammatory effects of plantderived coumarin derivatives
    • Witaicenis A, Seito LN, da Silveira Chagas A, et al. Antioxidant and intestinal anti-inflammatory effects of plantderived coumarin derivatives. Phytomedicine. 2014;21: 240-246.
    • (2014) Phytomedicine. , vol.21 , pp. 240-246
    • Witaicenis, A.1    Seito, L.N.2    Da Silveira Chagas, A.3
  • 81
    • 0017405214 scopus 로고
    • The effects of antioxidants on the metabolism and mutagenicity of benzo[a] pyrene in vitro
    • Rahimtula AD, Zachariah PK, O'Brien PJ. The effects of antioxidants on the metabolism and mutagenicity of benzo[a] pyrene in vitro. Biochem J. 1977;164:473-475.
    • (1977) Biochem J. , vol.164 , pp. 473-475
    • Rahimtula, A.D.1    Zachariah, P.K.2    O'Brien, P.J.3
  • 82
    • 0033521964 scopus 로고    scopus 로고
    • Lack of effect of coumarin in women with lymphedema after treatment for breast cancer
    • Loprinzi CL, Kugler JW, Sloan JA, et al. Lack of effect of coumarin in women with lymphedema after treatment for breast cancer. N Engl J Med. 1999;340:346-350.
    • (1999) N Engl J Med. , vol.340 , pp. 346-350
    • Loprinzi, C.L.1    Kugler, J.W.2    Sloan, J.A.3
  • 83
    • 0026214247 scopus 로고
    • Phase i evaluation of coumarin (1, 2-benzopyrone) and cimetidine in patients with advanced malignancies
    • Marshall ME, Butler K, Fried A. Phase I evaluation of coumarin (1, 2-benzopyrone) and cimetidine in patients with advanced malignancies. Mol Biother. 1991;3:170-178.
    • (1991) Mol Biother. , vol.3 , pp. 170-178
    • Marshall, M.E.1    Butler, K.2    Fried, A.3
  • 84
    • 0035095601 scopus 로고    scopus 로고
    • Prophylaxis of radiogenic sialadenitis and mucositis by coumarin/troxerutine in patients with head and neck cancer: A prospective, randomized, placebo-controlled, double-blind study
    • Grotz KA, Wustenberg P, Kohnen R, et al. Prophylaxis of radiogenic sialadenitis and mucositis by coumarin/troxerutine in patients with head and neck cancer: a prospective, randomized, placebo-controlled, double-blind study. Br J Oral Maxillofac Surg. 2001;39:34-39.
    • (2001) Br J Oral Maxillofac Surg. , vol.39 , pp. 34-39
    • Grotz, K.A.1    Wustenberg, P.2    Kohnen, R.3
  • 85
    • 34248573808 scopus 로고    scopus 로고
    • Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappa B-regulated gene products
    • Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, Aggarwal BB. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappa B-regulated gene products. Cancer Res. 2007;67:3853-3861.
    • (2007) Cancer Res. , vol.67 , pp. 3853-3861
    • Kunnumakkara, A.B.1    Guha, S.2    Krishnan, S.3    Diagaradjane, P.4    Gelovani, J.5    Aggarwal, B.B.6
  • 87
    • 84880532170 scopus 로고    scopus 로고
    • Curcumin for radiation dermatitis: A randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients
    • Ryan JL, Heckler CE, Ling M, et al. Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients. Radiat Res. 2013;180:34-43.
    • (2013) Radiat Res. , vol.180 , pp. 34-43
    • Ryan, J.L.1    Heckler, C.E.2    Ling, M.3
  • 88
    • 79959612772 scopus 로고    scopus 로고
    • A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
    • Kanai M, Yoshimura K, Asada M, et al. A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer. Cancer Chemother Pharmacol. 2011;68:157-164.
    • (2011) Cancer Chemother Pharmacol. , vol.68 , pp. 157-164
    • Kanai, M.1    Yoshimura, K.2    Asada, M.3
  • 89
    • 78249286547 scopus 로고    scopus 로고
    • Curcumin and gemcitabine in patients with advanced pancreatic cancer
    • Epelbaum R, Schaffer M, Vizel B, Badmaev V, Bar-Sela G. Curcumin and gemcitabine in patients with advanced pancreatic cancer. Nutr Cancer. 2010;62:1137-1141.
    • (2010) Nutr Cancer. , vol.62 , pp. 1137-1141
    • Epelbaum, R.1    Schaffer, M.2    Vizel, B.3    Badmaev, V.4    Bar-Sela, G.5
  • 90
    • 77954160638 scopus 로고    scopus 로고
    • Phase i dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
    • Bayet-Robert M, Kwiatkowski F, Leheurteur M, et al. Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer. Cancer Biol Ther. 2010;9:8-14.
    • (2010) Cancer Biol Ther. , vol.9 , pp. 8-14
    • Bayet-Robert, M.1    Kwiatkowski, F.2    Leheurteur, M.3
  • 91
    • 84879367480 scopus 로고    scopus 로고
    • The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead
    • Kasperczyk S, Dobrakowski M, Kasperczyk A, Ostalowska A, Birkner E. The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead. Clin Toxicol (Phila). 2013;51:480-486.
    • (2013) Clin Toxicol (Phila). , vol.51 , pp. 480-486
    • Kasperczyk, S.1    Dobrakowski, M.2    Kasperczyk, A.3    Ostalowska, A.4    Birkner, E.5
  • 92
    • 33646464224 scopus 로고    scopus 로고
    • N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: Preliminary data
    • Lin PC, Lee MY, Wang WS, et al. N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: preliminary data. Support Care Cancer. 2006;14:484-487.
    • (2006) Support Care Cancer. , vol.14 , pp. 484-487
    • Lin, P.C.1    Lee, M.Y.2    Wang, W.S.3
  • 93
    • 84880929179 scopus 로고    scopus 로고
    • L-Arginine and Vitamin D adjunctive therapies in pulmonary tuberculosis: A randomised, double-blind, placebo-controlled trial
    • Ralph AP, Waramori G, Pontororing GJ, et al. l-Arginine and vitamin D adjunctive therapies in pulmonary tuberculosis: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013;8:e70032.
    • (2013) PLoS One. , vol.8 , pp. e70032
    • Ralph, A.P.1    Waramori, G.2    Pontororing, G.J.3
  • 94
    • 84904305328 scopus 로고    scopus 로고
    • Effects of dietary arginine supplementation on growth performance, flesh quality, muscle antioxidant capacity and antioxidant-related signalling molecule expression in young grass carp (Ctenopharyngodon idella)
    • Wang B, Liu Y, Feng L, et al. Effects of dietary arginine supplementation on growth performance, flesh quality, muscle antioxidant capacity and antioxidant-related signalling molecule expression in young grass carp (Ctenopharyngodon idella). Food Chem. 2015;167:91-99.
    • (2015) Food Chem. , vol.167 , pp. 91-99
    • Wang, B.1    Liu, Y.2    Feng, L.3
  • 95
    • 0031974832 scopus 로고    scopus 로고
    • Potentiation of the response to chemotherapy in patients with breast cancer by dietary supplementation with L-arginine: Results of a randomised controlled trial
    • Heys SD, Ogston K, Miller I, et al. Potentiation of the response to chemotherapy in patients with breast cancer by dietary supplementation with L-arginine: results of a randomised controlled trial. Int J Oncol. 1998;12:221-225.
    • (1998) Int J Oncol. , vol.12 , pp. 221-225
    • Heys, S.D.1    Ogston, K.2    Miller, I.3
  • 99
    • 84879621492 scopus 로고    scopus 로고
    • Redox cycling of endogenous copper by thymoquinone leads to ROSmediated DNA breakage and consequent cell death: Putative anticancer mechanism of antioxidants
    • Zubair H, Khan HY, Sohail A, et al. Redox cycling of endogenous copper by thymoquinone leads to ROSmediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants. Cell Death Dis. 2013;4:e660.
    • (2013) Cell Death Dis. , vol.4 , pp. e660
    • Zubair, H.1    Khan, H.Y.2    Sohail, A.3
  • 100
    • 84859211841 scopus 로고    scopus 로고
    • Selenium and human health
    • Rayman MP. Selenium and human health. Lancet. 2012;37:1256-1268.
    • (2012) Lancet. , vol.37 , pp. 1256-1268
    • Rayman, M.P.1
  • 101
    • 84875308523 scopus 로고    scopus 로고
    • Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology: A subgroup analysis of a multicenter, phase III trial
    • Muecke R, Micke O, Schomburg L, et al. Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology: a subgroup analysis of a multicenter, phase III trial. Radiat Oncol. 2013;8:72.
    • (2013) Radiat Oncol. , vol.8 , pp. 72
    • Muecke, R.1    Micke, O.2    Schomburg, L.3
  • 102
    • 84921026456 scopus 로고    scopus 로고
    • Multicenter, phase III trial comparing selenium supplementation with observation in gynecologic radiation oncology: Follow-up analysis of the survival data 6 years after cessation of randomization
    • Muecke R, Micke O, Schomburg L, et al. Multicenter, phase III trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization. Integr Cancer Ther. 2014;13:463-467.
    • (2014) Integr Cancer Ther. , vol.13 , pp. 463-467
    • Muecke, R.1    Micke, O.2    Schomburg, L.3
  • 103
    • 77954583498 scopus 로고    scopus 로고
    • Limited effects of selenium substitution in the prevention of radiationassociated toxicities: Results of a randomized study in head and neck cancer patients
    • Buntzel J, Riesenbeck D, Glatzel M, et al. Limited effects of selenium substitution in the prevention of radiationassociated toxicities: results of a randomized study in head and neck cancer patients. Anticancer Res. 2010;30:1829-1832.
    • (2010) Anticancer Res. , vol.30 , pp. 1829-1832
    • Buntzel, J.1    Riesenbeck, D.2    Glatzel, M.3
  • 104
    • 8244221011 scopus 로고    scopus 로고
    • The protective role of selenium on the toxicity of cisplatin-contained chemotherapy regimen in cancer patients
    • Hu YJ, Chen Y, Zhang YQ, et al. The protective role of selenium on the toxicity of cisplatin-contained chemotherapy regimen in cancer patients. Biol Trace Elem Res. 1997;56:331-341.
    • (1997) Biol Trace Elem Res. , vol.56 , pp. 331-341
    • Hu, Y.J.1    Chen, Y.2    Zhang, Y.Q.3
  • 105
    • 1942508981 scopus 로고    scopus 로고
    • Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy
    • Sieja K, Talerczyk M. Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy. Gynecol Oncol. 2004;93:320-327.
    • (2004) Gynecol Oncol. , vol.93 , pp. 320-327
    • Sieja, K.1    Talerczyk, M.2
  • 106
    • 0035889679 scopus 로고    scopus 로고
    • Chemotherapyinduced chromosomal damage in peripheral blood lymphocytes of cancer patients supplemented with antioxidants or placebo
    • Elsendoorn TJ, Weijl NI, Mithoe S, et al. Chemotherapyinduced chromosomal damage in peripheral blood lymphocytes of cancer patients supplemented with antioxidants or placebo. Mutat Res. 2001;4:145-158.
    • (2001) Mutat Res. , vol.4 , pp. 145-158
    • Elsendoorn, T.J.1    Weijl, N.I.2    Mithoe, S.3
  • 107
    • 3142610921 scopus 로고    scopus 로고
    • Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: A randomised, double-blind, placebo-controlled study
    • Weijl NI, Elsendoorn TJ, Lentjes EG, et al. Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: a randomised, double-blind, placebo-controlled study. Eur J Cancer. 2004;40:1713-1723.
    • (2004) Eur J Cancer. , vol.40 , pp. 1713-1723
    • Weijl, N.I.1    Elsendoorn, T.J.2    Lentjes, E.G.3
  • 109
    • 84873198393 scopus 로고    scopus 로고
    • A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients
    • Sangthawan D, Phungrassami T, Sinkitjarurnchai W. A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients. J Med Assoc Thai. 2013;96:69-76.
    • (2013) J Med Assoc Thai. , vol.96 , pp. 69-76
    • Sangthawan, D.1    Phungrassami, T.2    Sinkitjarurnchai, W.3
  • 110
    • 0032525122 scopus 로고    scopus 로고
    • A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation
    • Ripamonti C, Zecca E, Brunelli C, et al. A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation. Cancer. 1998;82:1938-1945.
    • (1998) Cancer. , vol.82 , pp. 1938-1945
    • Ripamonti, C.1    Zecca, E.2    Brunelli, C.3
  • 111
    • 84863596829 scopus 로고    scopus 로고
    • A randomized, placebo controlled trial of oral zinc for chemotherapy- related taste and smell disorders
    • Lyckholm L, Heddinger SP, Parker G, et al. A randomized, placebo controlled trial of oral zinc for chemotherapy- related taste and smell disorders. J Pain Palliat Care Pharmacother. 2012;26:111-114.
    • (2012) J Pain Palliat Care Pharmacother. , vol.26 , pp. 111-114
    • Lyckholm, L.1    Heddinger, S.P.2    Parker, G.3
  • 112
    • 4344647769 scopus 로고    scopus 로고
    • The effects of oral zinc sulphate during radiotherapy on anti-oxidant enzyme activities in patients with head and neck cancer: A prospective, randomised, placebo-controlled study
    • Ertekin MV, Koc M, Karslioglu I, Sezen O, Taysi S, Bakan N. The effects of oral zinc sulphate during radiotherapy on anti-oxidant enzyme activities in patients with head and neck cancer: a prospective, randomised, placebo-controlled study. Int J Clin Pract. 2004;58:662-668.
    • (2004) Int J Clin Pract. , vol.58 , pp. 662-668
    • Ertekin, M.V.1    Koc, M.2    Karslioglu, I.3    Sezen, O.4    Taysi, S.5    Bakan, N.6
  • 113
    • 0042426155 scopus 로고    scopus 로고
    • Effect of oral zinc supplementation on agents of oropharyngeal infection in patients receiving radiotherapy for head and neck cancer
    • Ertekin MV, Uslu H, Karslioglu I, Ozbek E, Ozbek A. Effect of oral zinc supplementation on agents of oropharyngeal infection in patients receiving radiotherapy for head and neck cancer. J Int Med Res. 2003;31:253-266.
    • (2003) J Int Med Res. , vol.31 , pp. 253-266
    • Ertekin, M.V.1    Uslu, H.2    Karslioglu, I.3    Ozbek, E.4    Ozbek, A.5
  • 114
    • 0346363399 scopus 로고    scopus 로고
    • Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: A prospective, placebo-controlled, randomized study
    • Ertekin MV, Koc M, Karslioglu I, Sezen O. Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study. Int J Radiat Oncol Biol Phys. 2004;58:167-174.
    • (2004) Int J Radiat Oncol Biol Phys. , vol.58 , pp. 167-174
    • Ertekin, M.V.1    Koc, M.2    Karslioglu, I.3    Sezen, O.4
  • 115
    • 33947497226 scopus 로고    scopus 로고
    • Does zinc sulfate prevent therapy-induced taste alterations in head and neck cancer patients? Results of phase III double-blind, placebo-controlled trial from the North Central Cancer Treatment Group (N01C4)
    • Halyard MY, Jatoi A, Sloan JA, et al. Does zinc sulfate prevent therapy-induced taste alterations in head and neck cancer patients? results of phase III double-blind, placebo-controlled trial from the North Central Cancer Treatment Group (N01C4). Int J Radiat Oncol Biol Phys. 2007;67:1318-1322.
    • (2007) Int J Radiat Oncol Biol Phys. , vol.67 , pp. 1318-1322
    • Halyard, M.Y.1    Jatoi, A.2    Sloan, J.A.3
  • 118
    • 84886025026 scopus 로고    scopus 로고
    • Carboxyhaemoglobin levels, health and lifestyle perceptions in smokers converting from tobacco cigarettes to electronic cigarettes
    • van Staden SR, Groenewald M, Engelbrecht R, Becker PJ, Hazelhurst LT. Carboxyhaemoglobin levels, health and lifestyle perceptions in smokers converting from tobacco cigarettes to electronic cigarettes. S Afr Med J. 2013;103:865-868.
    • (2013) S Afr Med J. , vol.103 , pp. 865-868
    • Van Staden, S.R.1    Groenewald, M.2    Engelbrecht, R.3    Becker, P.J.4    Hazelhurst, L.T.5
  • 119
    • 84928919804 scopus 로고    scopus 로고
    • Tumor hypoxia enhances nonsmall cell lung cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling
    • Zhang J, Cao J, Ma S, et al. Tumor hypoxia enhances nonsmall cell lung cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling. Oncotarget. 2014;5:9664-9677.
    • (2014) Oncotarget. , vol.5 , pp. 9664-9677
    • Zhang, J.1    Cao, J.2    Ma, S.3
  • 120
    • 84911991734 scopus 로고    scopus 로고
    • Discoidin domain receptor 2 (DDR2) promotes breast cancer cell metastasis and the mechanism implicates epithelial-mesenchymal transition programme under hypoxia
    • Ren T, Zhang W, Liu X, et al. Discoidin domain receptor 2 (DDR2) promotes breast cancer cell metastasis and the mechanism implicates epithelial-mesenchymal transition programme under hypoxia. J Pathol. 2014;234:526-537.
    • (2014) J Pathol. , vol.234 , pp. 526-537
    • Ren, T.1    Zhang, W.2    Liu, X.3
  • 121
    • 35948995400 scopus 로고    scopus 로고
    • Mechanism of DNA damage and apoptosis induced by anticancer drugs through generation of reactive oxygen species
    • Mizutani H. Mechanism of DNA damage and apoptosis induced by anticancer drugs through generation of reactive oxygen species. Yakugaku Zasshi. 2007;127:1837-1842.
    • (2007) Yakugaku Zasshi. , vol.127 , pp. 1837-1842
    • Mizutani, H.1
  • 122
    • 0033847986 scopus 로고    scopus 로고
    • Dietary antioxidants during cancer chemotherapy: Impact on chemotherapeutic effectiveness and development of side effects
    • Conklin KA. Dietary antioxidants during cancer chemotherapy: impact on chemotherapeutic effectiveness and development of side effects. Nutr Cancer. 2000;37:1-18.
    • (2000) Nutr Cancer. , vol.37 , pp. 1-18
    • Conklin, K.A.1
  • 123
    • 24044481347 scopus 로고    scopus 로고
    • Nutritional interventions to counteract oxidative stress in cardiac cells
    • Hrelia S, Bordoni A, Angeloni C, Leoncini E, Biagi P. Nutritional interventions to counteract oxidative stress in cardiac cells. Ital J Biochem. 2004;53:157-163.
    • (2004) Ital J Biochem. , vol.53 , pp. 157-163
    • Hrelia, S.1    Bordoni, A.2    Angeloni, C.3    Leoncini, E.4    Biagi, P.5
  • 125
    • 58149260218 scopus 로고    scopus 로고
    • Cisplatin upregulates mitochondrial nitric oxide synthase and peroxynitrite formation to promote renal injury
    • Jung M, Hotter G, Vinas JL, Sola A. Cisplatin upregulates mitochondrial nitric oxide synthase and peroxynitrite formation to promote renal injury. Toxicol Appl Pharmacol. 2009;234:236-246.
    • (2009) Toxicol Appl Pharmacol. , vol.234 , pp. 236-246
    • Jung, M.1    Hotter, G.2    Vinas, J.L.3    Sola, A.4
  • 126
    • 70949103587 scopus 로고    scopus 로고
    • Role of proinflammatory cytokines IL-18 and IL-1beta in bleomycin-induced lung injury in humans and mice
    • Hoshino T, Okamoto M, Sakazaki Y, Kato S, Young HA, Aizawa H. Role of proinflammatory cytokines IL-18 and IL-1beta in bleomycin-induced lung injury in humans and mice. Am J Respir Cell Mol Biol. 2009;41:661-670.
    • (2009) Am J Respir Cell Mol Biol. , vol.41 , pp. 661-670
    • Hoshino, T.1    Okamoto, M.2    Sakazaki, Y.3    Kato, S.4    Young, H.A.5    Aizawa, H.6
  • 128
    • 84903899662 scopus 로고    scopus 로고
    • The promise and perils of antioxidants for cancer patients
    • Chandel NS, Tuveson DA. The promise and perils of antioxidants for cancer patients. N Engl J Med. 2014;371: 177-178.
    • (2014) N Engl J Med. , vol.371 , pp. 177-178
    • Chandel, N.S.1    Tuveson, D.A.2
  • 129
    • 81255205100 scopus 로고    scopus 로고
    • Systematic review: Generating evidence-based guidelines on the concurrent use of dietary antioxidants and chemotherapy or radiotherapy
    • Nakayama A, Alladin KP, Igbokwe O, White JD. Systematic review: generating evidence-based guidelines on the concurrent use of dietary antioxidants and chemotherapy or radiotherapy. Cancer Invest. 2011;29:655-667.
    • (2011) Cancer Invest. , vol.29 , pp. 655-667
    • Nakayama, A.1    Alladin, K.P.2    Igbokwe, O.3    White, J.D.4
  • 130
    • 84930926926 scopus 로고    scopus 로고
    • Nutritional supplements and cancer: Potential benefits and proven harms
    • Harvie M. Nutritional supplements and cancer: potential benefits and proven harms. Am Soc Clin Oncol Educ Book. 2014:e478-e486.
    • Am Soc Clin Oncol Educ Book. , vol.2014 , pp. e478-e486
    • Harvie, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.