Chimeric vaccine stimulation of human dendritic cell indoleamine 2, 3-dioxygenase occurs via the non-canonical NF-kB pathway

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Kim, Nan Sun ^a,b   Mbongue, Jacques C ^a   Nicholas, Dequina A ^a   Esebanmen, Grace E ^a   Unternaehrer, Juli J ^a   Firek, Anthony F ^c   Langridge, William H R ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Chonbuk National University   (South Korea)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN VACCINE; CHOLERA TOXIN B SUBUNIT; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLEAMINE 2,3 DIOXYGENASE; PROINSULIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELB; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VACCINE; CHOLERA TOXIN; HYBRID PROTEIN; I KAPPA B KINASE; INDOLEAMINE 2,3-DIOXYGENASE 1, HUMAN; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; TRAF3 PROTEIN, HUMAN;

ARTICLE; CELL STIMULATION; CHROMATIN IMMUNOPRECIPITATION; CONSENSUS SEQUENCE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VIVO STUDY; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; AMINO ACID SEQUENCE; ANIMAL; AUTOIMMUNITY; BIOSYNTHESIS; DIABETES MELLITUS, TYPE 1; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; NONOBESE DIABETIC MOUSE; NUCLEOTIDE SEQUENCE; PATHOLOGY;

AMINO ACID SEQUENCE; ANIMALS; AUTOIMMUNITY; BASE SEQUENCE; CHOLERA TOXIN; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; MICE; MICE, INBRED NOD; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROINSULIN; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TNF RECEPTOR-ASSOCIATED FACTOR 3; TNF RECEPTOR-ASSOCIATED FACTOR 6; VACCINES;

EID: 84960433496     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0147509     Document Type: Article

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