Analysis of small molecule antibody-drug conjugate catabolites in rat liver and tumor tissue by liquid extraction surface analysis micro-capillary liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 30, Issue 7, 2016, Pages 823-832

  Lanshoeft, Christian ^a   Stutz, Gerhard ^a   Elbast, Walid ^a   Wolf, Thierry ^a   Walles, Markus ^a   Stoeckli, Markus ^a   Picard, Franck ^a   Kretz, Olivier ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ASSAYS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; QUALITY CONTROL; RADIOGRAPHY; RATS; TUMORS;

ANTIBODY-DRUG CONJUGATES; CAPILLARY LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; LIQUID EXTRACTION; LIVER TISSUE; MICRO-CAPILLARIES; RAT LIVERS; TUMOUR TISSUE; [CARBONYL;

SURFACE ANALYSIS;

ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; MALEIMIDE DERIVATIVE; MAYTANSINE;

ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; LIVER; METABOLISM; MOLECULAR IMAGING; NEOPLASM; PROCEDURES; RAT; REPRODUCIBILITY; STATISTICAL MODEL; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, LIQUID; IMMUNOCONJUGATES; LINEAR MODELS; LIQUID-LIQUID EXTRACTION; LIVER; MALEIMIDES; MAYTANSINE; MODELS, BIOLOGICAL; MOLECULAR IMAGING; NEOPLASMS; RATS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84960411517     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.7511     Document Type: Article

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