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Volumn 74, Issue , 2016, Pages 44-59

Surface proteome analysis identifies platelet derived growth factor receptor-alpha as a critical mediator of transforming growth factor-beta-induced collagen secretion

Author keywords

Cell signaling; Cell surface; Mass spectrometry; Pulmonary fibrosis fibroblasts; Surface proteome

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA ACTIN; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; CALCYCLIN; CD146 ANTIGEN; CD82 ANTIGEN; CELL SURFACE PROTEIN; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 5; DECAY ACCELERATING FACTOR; FIBRONECTIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE TRANSPORTER 1; INITIATION FACTOR 4G; JUNCTIONAL ADHESION MOLECULE C; PLATELET DERIVED GROWTH FACTOR AB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEOME; SMAD3 PROTEIN; SMALL INTERFERING RNA; SODIUM PROTON EXCHANGE PROTEIN 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; WNT5A PROTEIN; MEMBRANE ANTIGEN;

EID: 84960376024     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2016.02.013     Document Type: Article
Times cited : (13)

References (57)
  • 1
    • 44149090296 scopus 로고    scopus 로고
    • Role of platelet-derived growth factors in physiology and medicine
    • J. Andrae, R. Gallini, and C. Betsholtz Role of platelet-derived growth factors in physiology and medicine Genes Dev. 22 2008 1276 1312
    • (2008) Genes Dev. , vol.22 , pp. 1276-1312
    • Andrae, J.1    Gallini, R.2    Betsholtz, C.3
  • 2
    • 0035003785 scopus 로고    scopus 로고
    • PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor
    • E. Bergsten, M. Uutela, X. Li, K. Pietras, A. Ostman, C.H. Heldin, and et al. PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor Nat. Cell Biol. 3 2001 512 516
    • (2001) Nat. Cell Biol. , vol.3 , pp. 512-516
    • Bergsten, E.1    Uutela, M.2    Li, X.3    Pietras, K.4    Ostman, A.5    Heldin, C.H.6
  • 3
    • 84922333220 scopus 로고    scopus 로고
    • Remodelling the extracellular matrix in development and disease
    • C. Bonnans, J. Chou, and Z. Werb Remodelling the extracellular matrix in development and disease Nat. Rev. Mol. Cell Biol. 15 2014 786 801
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , pp. 786-801
    • Bonnans, C.1    Chou, J.2    Werb, Z.3
  • 4
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • J.C. Bonner Regulation of PDGF and its receptors in fibrotic diseases Cytokine Growth Factor Rev. 15 2004 255 273
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 255-273
    • Bonner, J.C.1
  • 5
    • 0029391470 scopus 로고
    • Transforming growth factor beta 1 downregulates the platelet-derived growth factor alpha-receptor subtype on human lung fibroblasts in vitro
    • J.C. Bonner, A. Badgett, P.M. Lindroos, and A.R. Osornio-Vargas Transforming growth factor beta 1 downregulates the platelet-derived growth factor alpha-receptor subtype on human lung fibroblasts in vitro Am. J. Respir. Cell Mol. Biol. 13 1995 496 505
    • (1995) Am. J. Respir. Cell Mol. Biol. , vol.13 , pp. 496-505
    • Bonner, J.C.1    Badgett, A.2    Lindroos, P.M.3    Osornio-Vargas, A.R.4
  • 6
    • 0026010305 scopus 로고
    • Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
    • T.J. Broekelmann, A.H. Limper, T.V. Colby, and J.A. McDonald Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis Proc. Natl. Acad. Sci. USA 88 1991 6642 6646
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6642-6646
    • Broekelmann, T.J.1    Limper, A.H.2    Colby, T.V.3    McDonald, J.A.4
  • 7
    • 67049118923 scopus 로고    scopus 로고
    • Accurate and sensitive peptide identification with Mascot Percolator
    • M. Brosch, L. Yu, T. Hubbard, and J. Choudhary Accurate and sensitive peptide identification with Mascot Percolator J. Proteome Res. 8 2009 3176 3181
    • (2009) J. Proteome Res. , vol.8 , pp. 3176-3181
    • Brosch, M.1    Yu, L.2    Hubbard, T.3    Choudhary, J.4
  • 9
    • 84931858195 scopus 로고    scopus 로고
    • Platelet-derived growth factor and transforming growth factor beta1 regulate ARDS-associated lung fibrosis through distinct signaling pathways
    • X. Deng, K. Jin, Y. Li, W. Gu, M. Liu, and L. Zhou Platelet-derived growth factor and transforming growth factor beta1 regulate ARDS-associated lung fibrosis through distinct signaling pathways Cell Physiol. Biochem. 36 2015 937 946
    • (2015) Cell Physiol. Biochem. , vol.36 , pp. 937-946
    • Deng, X.1    Jin, K.2    Li, Y.3    Gu, W.4    Liu, M.5    Zhou, L.6
  • 10
    • 84877267948 scopus 로고    scopus 로고
    • Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts
    • J. Donovan, X. Shiwen, J. Norman, and D. Abraham Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts Fibrogenesis Tissue Repair 6 2013 10
    • (2013) Fibrogenesis Tissue Repair , vol.6 , pp. 10
    • Donovan, J.1    Shiwen, X.2    Norman, J.3    Abraham, D.4
  • 11
    • 58849126879 scopus 로고    scopus 로고
    • Three-dimensional context regulation of metastasis
    • J.T. Erler, and V.M. Weaver Three-dimensional context regulation of metastasis Clin. Exp. Metastasis 26 2009 35 49
    • (2009) Clin. Exp. Metastasis , vol.26 , pp. 35-49
    • Erler, J.T.1    Weaver, V.M.2
  • 12
    • 84872521042 scopus 로고    scopus 로고
    • Bovine neonatal pancytopenia - Comparative proteomic characterization of two BVD vaccines and the producer cell surface proteome (MDBK)
    • K.N. Euler, S.M. Hauck, M. Ueffing, and C.A. Deeg Bovine neonatal pancytopenia - comparative proteomic characterization of two BVD vaccines and the producer cell surface proteome (MDBK) BMC Vet. Res. 9 2013 18
    • (2013) BMC Vet. Res. , vol.9 , pp. 18
    • Euler, K.N.1    Hauck, S.M.2    Ueffing, M.3    Deeg, C.A.4
  • 13
    • 78649737455 scopus 로고    scopus 로고
    • The extracellular matrix at a glance
    • C. Frantz, K.M. Stewart, and V.M. Weaver The extracellular matrix at a glance J. Cell Sci. 123 2010 4195 4200
    • (2010) J. Cell Sci. , vol.123 , pp. 4195-4200
    • Frantz, C.1    Stewart, K.M.2    Weaver, V.M.3
  • 14
    • 0242710145 scopus 로고    scopus 로고
    • Collagens - Structure, function, and biosynthesis
    • K. Gelse, E. Poschl, and T. Aigner Collagens - structure, function, and biosynthesis Adv. Drug Deliv. Rev. 55 2003 1531 1546
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 1531-1546
    • Gelse, K.1    Poschl, E.2    Aigner, T.3
  • 15
    • 84938907265 scopus 로고    scopus 로고
    • A combined omics approach to generate the surface atlas of human naive CD4+ T cells during early T-Cell receptor activation
    • A. Graessel, S.M. Hauck, C. von Toerne, E. Kloppmann, T. Goldberg, H. Koppensteiner, and et al. A combined omics approach to generate the surface atlas of human naive CD4+ T cells during early T-Cell receptor activation Mol. Cell Proteomics 14 2015 2085 2102
    • (2015) Mol. Cell Proteomics , vol.14 , pp. 2085-2102
    • Graessel, A.1    Hauck, S.M.2    Von Toerne, C.3    Kloppmann, E.4    Goldberg, T.5    Koppensteiner, H.6
  • 17
    • 77958004256 scopus 로고    scopus 로고
    • Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry
    • S.M. Hauck, J. Dietter, R.L. Kramer, F. Hofmaier, J.K. Zipplies, B. Amann, and et al. Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry Mol. Cell Proteomics 9 2010 2292 2305
    • (2010) Mol. Cell Proteomics , vol.9 , pp. 2292-2305
    • Hauck, S.M.1    Dietter, J.2    Kramer, R.L.3    Hofmaier, F.4    Zipplies, J.K.5    Amann, B.6
  • 18
    • 0024007666 scopus 로고
    • Binding of different dimeric forms of PDGF to human fibroblasts: Evidence for two separate receptor types
    • C.H. Heldin, G. Backstrom, A. Ostman, A. Hammacher, L. Ronnstrand, K. Rubin, and et al. Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types EMBO J. 7 1988 1387 1393
    • (1988) EMBO J. , vol.7 , pp. 1387-1393
    • Heldin, C.H.1    Backstrom, G.2    Ostman, A.3    Hammacher, A.4    Ronnstrand, L.5    Rubin, K.6
  • 20
    • 50849145156 scopus 로고    scopus 로고
    • Collagen fibrillogenesis: Fibronectin, integrins, and minor collagens as organizers and nucleators
    • K.E. Kadler, A. Hill, and E.G. Canty-Laird Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators Curr. Opin. Cell Biol. 20 2008 495 501
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 495-501
    • Kadler, K.E.1    Hill, A.2    Canty-Laird, E.G.3
  • 21
  • 22
    • 0030076509 scopus 로고    scopus 로고
    • TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: An immunohistochemical study
    • N. Khalil, R.N. O'Connor, K.C. Flanders, and H. Unruh TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study Am. J. Respir. Cell Mol. Biol. 14 1996 131 138
    • (1996) Am. J. Respir. Cell Mol. Biol. , vol.14 , pp. 131-138
    • Khalil, N.1    O'Connor, R.N.2    Flanders, K.C.3    Unruh, H.4
  • 23
    • 84910601354 scopus 로고    scopus 로고
    • Prestress in the extracellular matrix sensitizes latent TGF-beta1 for activation
    • F. Klingberg, M.L. Chow, A. Koehler, S. Boo, L. Buscemi, T.M. Quinn, and et al. Prestress in the extracellular matrix sensitizes latent TGF-beta1 for activation J. Cell Biol. 207 2014 283 297
    • (2014) J. Cell Biol. , vol.207 , pp. 283-297
    • Klingberg, F.1    Chow, M.L.2    Koehler, A.3    Boo, S.4    Buscemi, L.5    Quinn, T.M.6
  • 24
    • 84888629584 scopus 로고    scopus 로고
    • Surface markers distinguishing mesenchymal stem cells from fibroblasts
    • G. Kundrotas Surface markers distinguishing mesenchymal stem cells from fibroblasts Acta. Med. Litu. 19 2012 75 79
    • (2012) Acta. Med. Litu. , vol.19 , pp. 75-79
    • Kundrotas, G.1
  • 25
    • 84864148484 scopus 로고    scopus 로고
    • TGF-beta/Smad signaling in kidney disease
    • H.Y. Lan, and A.C. Chung TGF-beta/Smad signaling in kidney disease Semin. Nephrol. 32 2012 236 243
    • (2012) Semin. Nephrol. , vol.32 , pp. 236-243
    • Lan, H.Y.1    Chung, A.C.2
  • 26
  • 27
    • 77953896432 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • M.A. Lemmon, and J. Schlessinger Cell signaling by receptor tyrosine kinases Cell 141 2010 1117 1134
    • (2010) Cell , vol.141 , pp. 1117-1134
    • Lemmon, M.A.1    Schlessinger, J.2
  • 28
    • 84907519671 scopus 로고    scopus 로고
    • PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors
    • C. Liu, J. Li, X. Xiang, L. Guo, K. Tu, Q. Liu, and et al. PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors Am. J. Physiol. Gastrointest. Liver Physiol. 307 2014 G749 G759
    • (2014) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.307 , pp. G749-G759
    • Liu, C.1    Li, J.2    Xiang, X.3    Guo, L.4    Tu, K.5    Liu, Q.6
  • 29
    • 33645960124 scopus 로고    scopus 로고
    • Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis
    • X. Liu, H. Hu, and J.Q. Yin Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis Liver Int. 26 2006 8 22
    • (2006) Liver Int. , vol.26 , pp. 8-22
    • Liu, X.1    Hu, H.2    Yin, J.Q.3
  • 31
    • 33847676783 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts: Their source, function and role in disease
    • R.J. McAnulty Fibroblasts and myofibroblasts: Their source, function and role in disease IJBCB 39 2007 666 671
    • (2007) IJBCB , vol.39 , pp. 666-671
    • McAnulty, R.J.1
  • 32
    • 84862996761 scopus 로고    scopus 로고
    • Direct comparison of MS-based label-free and SILAC quantitative proteome profiling strategies in primary retinal Muller cells
    • J. Merl, M. Ueffing, S.M. Hauck, and C. von Toerne Direct comparison of MS-based label-free and SILAC quantitative proteome profiling strategies in primary retinal Muller cells Proteomics 12 2012 1902 1911
    • (2012) Proteomics , vol.12 , pp. 1902-1911
    • Merl, J.1    Ueffing, M.2    Hauck, S.M.3    Von Toerne, C.4
  • 33
    • 84866116442 scopus 로고    scopus 로고
    • Zyxin is a transforming growth factor-beta (TGF-beta)/Smad3 target gene that regulates lung cancer cell motility via integrin alpha5beta1
    • N. Mise, R. Savai, H. Yu, J. Schwarz, N. Kaminski, and O. Eickelberg Zyxin is a transforming growth factor-beta (TGF-beta)/Smad3 target gene that regulates lung cancer cell motility via integrin alpha5beta1 J. Biol. Chem. 287 2012 31393 31405
    • (2012) J. Biol. Chem. , vol.287 , pp. 31393-31405
    • Mise, N.1    Savai, R.2    Yu, H.3    Schwarz, J.4    Kaminski, N.5    Eickelberg, O.6
  • 35
    • 0027918158 scopus 로고
    • Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors
    • J. Murray-Rust, N.Q. McDonald, T.L. Blundell, M. Hosang, C. Oefner, F. Winkler, and et al. Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors Structure 1 1993 153 159
    • (1993) Structure , vol.1 , pp. 153-159
    • Murray-Rust, J.1    McDonald, N.Q.2    Blundell, T.L.3    Hosang, M.4    Oefner, C.5    Winkler, F.6
  • 36
    • 84924110255 scopus 로고    scopus 로고
    • PDGF signaling in the lung - From lung development and disease to clinical studies
    • Mar.
    • N. Noskovicova, M. Petrek, O. Eickelberg, and K. Heinzelmann PDGF signaling in the lung - from lung development and disease to clinical studies Am. J. Respir. Cell Mol. Biol. 52 3 2015 Mar 263 284 10.1165/rcmb.2014-0294TR
    • (2015) Am. J. Respir. Cell Mol. Biol. , vol.52 , Issue.3 , pp. 263-284
    • Noskovicova, N.1    Petrek, M.2    Eickelberg, O.3    Heinzelmann, K.4
  • 37
    • 84904154934 scopus 로고    scopus 로고
    • Platelet-derived growth factor beta-receptor, transforming growth factor beta type I receptor, and CD44 protein modulate each other's signaling and stability
    • H. Porsch, M. Mehic, B. Olofsson, P. Heldin, and C.H. Heldin Platelet-derived growth factor beta-receptor, transforming growth factor beta type I receptor, and CD44 protein modulate each other's signaling and stability J. Biol. Chem. 289 2014 19747 19757
    • (2014) J. Biol. Chem. , vol.289 , pp. 19747-19757
    • Porsch, H.1    Mehic, M.2    Olofsson, B.3    Heldin, P.4    Heldin, C.H.5
  • 38
    • 0037154107 scopus 로고    scopus 로고
    • Monitoring of gene expression by functional proteomics: Response of human lung fibroblast cells to stimulation by endothelin-1
    • J. Predic, V. Soskic, D. Bradley, and J. Godovac-Zimmermann Monitoring of gene expression by functional proteomics: response of human lung fibroblast cells to stimulation by endothelin-1 Biochemistry 41 2002 1070 1078
    • (2002) Biochemistry , vol.41 , pp. 1070-1078
    • Predic, J.1    Soskic, V.2    Bradley, D.3    Godovac-Zimmermann, J.4
  • 39
    • 0024307964 scopus 로고
    • Collagen synthesis by normal and fibrotic human lung fibroblasts and the effect of transforming growth factor-beta
    • G. Raghu, S. Masta, D. Meyers, and A.S. Narayanan Collagen synthesis by normal and fibrotic human lung fibroblasts and the effect of transforming growth factor-beta Am. Rev. Respir. Dis. 140 1989 95 100
    • (1989) Am. Rev. Respir. Dis. , vol.140 , pp. 95-100
    • Raghu, G.1    Masta, S.2    Meyers, D.3    Narayanan, A.S.4
  • 41
    • 84877086317 scopus 로고    scopus 로고
    • Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
    • N. Sakai, and A.M. Tager Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis Biochim. Biophys. Acta 1832 2013 911 921
    • (2013) Biochim. Biophys. Acta , vol.1832 , pp. 911-921
    • Sakai, N.1    Tager, A.M.2
  • 43
    • 35448988114 scopus 로고    scopus 로고
    • Molecular targets in pulmonary fibrosis: The myofibroblast in focus
    • C.J. Scotton, and R.C. Chambers Molecular targets in pulmonary fibrosis: the myofibroblast in focus Chest 132 2007 1311 1321
    • (2007) Chest , vol.132 , pp. 1311-1321
    • Scotton, C.J.1    Chambers, R.C.2
  • 44
    • 84882237753 scopus 로고    scopus 로고
    • Extracellular matrix microenvironment contributes actively to pulmonary fibrosis
    • C. Shimbori, J. Gauldie, and M. Kolb Extracellular matrix microenvironment contributes actively to pulmonary fibrosis Curr. Opin. Pulm. Med. 19 2013 446 452
    • (2013) Curr. Opin. Pulm. Med. , vol.19 , pp. 446-452
    • Shimbori, C.1    Gauldie, J.2    Kolb, M.3
  • 45
    • 84935893393 scopus 로고    scopus 로고
    • Plasticity of fibroblasts demonstrated by tissue-specific and function-related proteome profiling
    • A.M. Slany, A. Beer, A. Ankersmit, H.J. Paulitschke, and V.Ch. Gerner Plasticity of fibroblasts demonstrated by tissue-specific and function-related proteome profiling Clin. Proteomics 11 2014 41
    • (2014) Clin. Proteomics , vol.11 , pp. 41
    • Slany, A.M.1    Beer, A.2    Ankersmit, A.3    Paulitschke, H.J.4    Gerner, V.Ch.5
  • 46
    • 0029909655 scopus 로고    scopus 로고
    • Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB)
    • R. Somasundaram, and D. Schuppan Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB) J. Biol. Chem. 271 1996 26884 26891
    • (1996) J. Biol. Chem. , vol.271 , pp. 26884-26891
    • Somasundaram, R.1    Schuppan, D.2
  • 48
  • 49
    • 84904126477 scopus 로고    scopus 로고
    • In situ cell surface proteomics reveals differentially expressed membrane proteins in retinal pigment epithelial cells during autoimmune uveitis
    • P.B. Uhl, C.M. Szober, B. Amann, C. Alge-Priglinger, M. Ueffing, S.M. Hauck, and et al. In situ cell surface proteomics reveals differentially expressed membrane proteins in retinal pigment epithelial cells during autoimmune uveitis J. Proteomics 109 2014 50 62
    • (2014) J. Proteomics , vol.109 , pp. 50-62
    • Uhl, P.B.1    Szober, C.M.2    Amann, B.3    Alge-Priglinger, C.4    Ueffing, M.5    Hauck, S.M.6
  • 52
    • 67349266694 scopus 로고    scopus 로고
    • Universal sample preparation method for proteome analysis
    • J.R. Wisniewski, A. Zougman, N. Nagaraj, and M. Mann Universal sample preparation method for proteome analysis Nat. Methods 6 2009 359 362
    • (2009) Nat. Methods , vol.6 , pp. 359-362
    • Wisniewski, J.R.1    Zougman, A.2    Nagaraj, N.3    Mann, M.4
  • 54
    • 64349089985 scopus 로고    scopus 로고
    • Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins
    • B. Wollscheid, D. Bausch-Fluck, C. Henderson, R. O'Brien, M. Bibel, R. Schiess, and et al. Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins Nat. Biotechnol. 27 2009 378 386
    • (2009) Nat. Biotechnol. , vol.27 , pp. 378-386
    • Wollscheid, B.1    Bausch-Fluck, D.2    Henderson, C.3    O'Brien, R.4    Bibel, M.5    Schiess, R.6
  • 55
    • 0026540461 scopus 로고
    • Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts
    • A. Yamakage, K. Kikuchi, E.A. Smith, E.C. LeRoy, and M. Trojanowska Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts J. Exp. Med. 175 1992 1227 1234
    • (1992) J. Exp. Med. , vol.175 , pp. 1227-1234
    • Yamakage, A.1    Kikuchi, K.2    Smith, E.A.3    LeRoy, E.C.4    Trojanowska, M.5
  • 56
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-beta signaling
    • Y.E. Zhang Non-Smad pathways in TGF-beta signaling Cell Res. 19 2009 128 139
    • (2009) Cell Res. , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 57
    • 0346096889 scopus 로고    scopus 로고
    • Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis
    • Y. Zhuo, J. Zhang, M. Laboy, and J.A. Lasky Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis Am. J. Physiol. Lung Cell Mol. Physiol. 286 2004 L182 L188
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.286 , pp. L182-L188
    • Zhuo, Y.1    Zhang, J.2    Laboy, M.3    Lasky, J.A.4


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