Plaque size is decreased but M1 macrophage polarization and rupture related metalloproteinase expression are maintained after deleting T-Bet in ApoE Null Mice

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Tsaous, Aikaterini ^a   Hayes, Elaine M ^a   Di Gregoli, Karina ^a   Bond, Andrew R ^a   Bevan, Laura ^a   Thomas, Anita C ^a   Newby, Andrew C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; APOLIPOPROTEIN E; ARGINASE 1; CD206 ANTIGEN; CELL PROTEIN; COLLAGENASE 3; CYCLOOXYGENASE 2; GELATINASE A; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 19; MATRIX METALLOPROTEINASE 23; MATRIX METALLOPROTEINASE 25; MESSENGER RNA; NEUTROPHIL COLLAGENASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; YM 1 PROTEIN; COLONY STIMULATING FACTOR 1; CYTOKINE; LIPID; LY ANTIGEN; LY-6C ANTIGEN, MOUSE; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ANIMAL CELL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA SINUS; ARTICLE; ATHEROSCLEROTIC PLAQUE; BRACHIOCEPHALIC TRUNK; CELL ACTIVATION; CELL ISOLATION; CELL POLARITY; CONTROLLED STUDY; GENE DELETION; GENOTYPE; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LIPID DIET; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SKIN GRANULOMA; ANIMAL; AORTA; ASCITES FLUID; BLOOD; C57BL MOUSE; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; FLOW CYTOMETRY; GENETICS; GRANULOMA; MACROPHAGE ACTIVATION; METABOLISM; PATHOLOGY; PERITONEUM MACROPHAGE; PHENOTYPE; SPLEEN;

ANIMALS; ANTIGENS, LY; AORTA; APOLIPOPROTEINS E; ASCITIC FLUID; CELL POLARITY; CYTOKINES; DIET, HIGH-FAT; FLOW CYTOMETRY; GENE DELETION; GRANULOMA; IMMUNOHISTOCHEMISTRY; LIPIDS; MACROPHAGE ACTIVATION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MACROPHAGES, PERITONEAL; MATRIX METALLOPROTEINASES; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; T-BOX DOMAIN PROTEINS; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 84960356803     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148873     Document Type: Article

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