Children with health impairments by heavy metals in an e-waste recycling area

Chemosphere

Volumn 148, Issue , 2016, Pages 408-415

  Zeng, Xiang ^a,b   Xu, Xijin ^a   Boezen, H Marike ^b   Huo, Xia ^c  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c JINAN UNIVERSITY   (China)

Author keywords

Children; Electronic waste; Exposure; Guiyu; Heavy metals

Indexed keywords

CHROMOSOMES; ELECTRONIC EQUIPMENT; HEALTH; HEAVY METALS; RECYCLING; WASTES;

ANOGENITAL DISTANCE; CHEMICAL COMPOSITIONS; CHILDREN; ELECTRONIC WASTE (E WASTE); ENVIRONMENTAL HEALTH; EXPOSURE; GUIYU; MANUAL DISMANTLING;

ELECTRONIC WASTE;

ALUMINUM; ARSENIC; CADMIUM; CHROMIUM; COBALT; COPPER; HEAVY METAL; HEPATITIS B SURFACE ANTIBODY; LEAD; MANGANESE; MERCURY; NICKEL; ZINC;

BURNING; CHILD HEALTH; CHROMOSOME; ENVIRONMENTAL EFFECT; GLOBAL PERSPECTIVE; HEALTH RISK; HEAVY METAL; POLLUTION EXPOSURE; PUBLIC HEALTH; RECYCLING;

ANOGENITAL DISTANCE; APGAR SCORE; ATTENTION DEFICIT DISORDER; BONE DISEASE; CARDIOVASCULAR DISEASE; CHEMICAL COMPOSITION; CHEMICAL REACTION; CHILDHOOD DISEASE; CHROMOSOME DAMAGE; DNA DAMAGE; ELECTRONIC WASTE; HEAVY METAL POISONING; HUMAN; IMMUNOPATHOLOGY; IMMUNOTOXICITY; LOW BIRTH WEIGHT; LUNG FUNCTION; NEUROLOGIC DISEASE; OXIDATIVE STRESS; PREVALENCE; RECYCLING; REPRODUCTIVE TOXICITY; REVIEW; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT DISEASE; ADVERSE EFFECTS; ANALYSIS; BLOOD; CHILD; CHILD HEALTH; CHINA; ENVIRONMENTAL EXPOSURE; STANDARDS;

CHINA; GUANGDONG; GUIYU;

CHILD; CHILD HEALTH; CHINA; ELECTRONIC WASTE; ENVIRONMENTAL EXPOSURE; HUMANS; METALS, HEAVY; RECYCLING;

EID: 84960352380     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2015.10.078     Document Type: Review

References (117)

1. Al-Saleh I., Shinwari N., Mashhour A., Rabah A. Birth outcome measures and maternal exposure to heavy metals (lead, cadmium and mercury) in Saudi Arabian population. Int. J. Hyg. Environ. Health 2014, 217:205-218.
2. Bellinger D., Leviton A., Waternaux C., Needleman H., Rabinowitz M. Longitudinal analyses of prenatal and postnatal lead exposure and early cognitive development. N. Engl. J. Med. 1987, 316:1037-1043.
3. Betts K.S. CDC updates guidelines for children's lead exposure. Environ. Health Perspect. 2012, 120:a268.
4. Boffetta P., Merler E., Vainio H. Carcinogenicity of mercury and mercury compounds. Scand. J. Work Environ. Health 1993, 19:1-7.
5. Braun J.M., Kahn R.S., Froehlich T., Auinger P., Lanphear B.P. Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environ. Health Perspect. 2006, 114:1904-1909.
6. Breivik K., Armitage J.M., Wania F., Jones K.C. Tracking the global generation and exports of e-waste. Do existing estimates add up?. Environ. Sci. Technol. 2014, 48:8735-8743.
7. Buchet J.P., Lauwerys R., Roels H., Bernard A., Bruaux P., Claeys F., Ducoffre G., de Plaen P., Staessen J., Amery A., Et A. Renal effects of cadmium body burden of the general population. Lancet 1990, 336:699-702.
8. Cardenas A., Roels H., Bernard A.M., Barbon R., Buchet J.P., Lauwerys R.R., Rosello J., Ramis I., Mutti A., Franchini I., Et A. Markers of early renal changes induced by industrial pollutants. II. Application to workers exposed to lead. Br. J. Ind. Med. 1993, 50:28-36.
9. Chang H.R., Tsao D.A., Yu H.S., Ho C.K. The change of beta-adrenergic system after cessation of lead exposure. Toxicology 2005, 207:73-80.
10. Chang S.H., Cheng B.H., Lee S.L., Chuang H.Y., Yang C.Y., Sung F.C., Wu T.N. Low blood lead concentration in association with infertility in women. Environ. Res. 2006, 101:380-386.
11. Chen A., Dietrich K.N., Huo X., Ho S.M. Developmental neurotoxicants in e-waste: an emerging health concern. Environ. Health Perspect. 2011, 119:431-438.
12. Chen L., Guo H., Yuan J., He M., Chen D., Shi J., Yang J., Bai Y., Ju Y., Liu A., Yu Z., Li L., Sheng G., Fu J., Wu T., Chen X. Polymorphisms of GSTT1 and GSTM1 and increased micronucleus frequencies in peripheral blood lymphocytes in residents at an e-waste dismantling site in China. J. Environ. Sci. Health A Toxic Hazard Subst. Environ. Eng. 2010, 45:490-497.
13. Chen X., Zhu G., Jin T., Lei L., Liang Y. Bone mineral density is related with previous renal dysfunction caused by cadmium exposure. Environ. Toxicol. Pharmacol. 2011, 32:46-53.
14. Chia S.E., Ong C.N., Lee S.T., Tsakok F.H. Blood concentrations of lead, cadmium, mercury, zinc, and copper and human semen parameters. Arch. Androl. 1992, 29:177-183.
15. Damek-Poprawa M., Sawicka-Kapusta K. Damage to the liver, kidney, and testis with reference to burden of heavy metals in yellow-necked mice from areas around steelworks and zinc smelters in Poland. Toxicology 2003, 186:1-10.
16. Davies S., McLaren H.J., Hunnisett A., Howard M. Age-related decreases in chromium levels in 51,665 hair, sweat, and serum samples from 40,872 patients-implications for the prevention of cardiovascular disease and type II diabetes mellitus. Metabolism 1997, 46:469-473.
17. Dursun N., Arifoglu C., Suer C., Keskinol L. Blood pressure relationship to nitric oxide, lipid peroxidation, renal function, and renal blood flow in rats exposed to low lead levels. Biol. Trace Elem. Res. 2005, 104:141-149.
18. Engstrom A., Michaelsson K., Vahter M., Julin B., Wolk A., Akesson A. Associations between dietary cadmium exposure and bone mineral density and risk of osteoporosis and fractures among women. Bone 2012, 50:1372-1378.
19. Fenech M. Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death. Mutat. Res. 2006, 600:58-66.
20. Fischbein A., Tsang P., Luo J.C., Roboz J.P., Jiang J.D., Bekesi J.G. Phenotypic aberrations of CD3+ and CD4+ cells and functional impairments of lymphocytes at low-level occupational exposure to lead. Clin. Immunol. Immunopathol. 1993, 66:163-168.
21. FRIBERG L. Health hazards in the manufacture of alkaline accumulators with special reference to chronic cadmium poisoning; a clinical and experimental study. Acta Med. Scand. Suppl. 1950, 240:1-124.
22. Fujiwara Y., Kaji T. Possible mechanism for lead inhibition of vascular endothelial cell proliferation: a lower response to basic fibroblast growth factor through inhibition of heparan sulfate synthesis. Toxicology 1999, 133:147-157.
23. Fujiwara Y., Watanabe S., Sakamoto M., Kaji T. Repair of wounded monolayers of cultured vascular endothelial cells after simultaneous exposure to lead and zinc. Toxicol. Lett. 1998, 94:181-188.
24. de Garbino J.P. Children's Health and the Environment: a Global Perspective. A Resource Manual for the Health Sector 2004, New York World Health Organization.
25. Glenn B.S., Bandeen-Roche K., Lee B.K., Weaver V.M., Todd A.C., Schwartz B.S. Changes in systolic blood pressure associated with lead in blood and bone. Epidemiology 2006, 17:538-544.
26. Goldman L.R., Shannon M.W. Technical report: mercury in the environment: implications for pediatricians. Pediatrics 2001, 108:197-205.
27. Grant K., Goldizen F.C., Sly P.D., Brune M., Neira M., van den Berg M., Norman R.E. Health consequences of exposure to e-waste: a systematic review. Lancet Glob. Health 2013, 1:e350-e361.
28. Heacock M., Kelly C.B., Asante K.A., Birnbaum L.S., Bergman A.L., Brune M.N., Buka I., Carpenter D.O., Chen A., Huo X., Kamel M., Landrigan P.J., Magalini F., Diaz-Barriga F., Neira M., Omar M., Pascale A., Ruchirawat M., Sly L., Sly P.D., Van den Berg M., Suk W.A. E-waste and harm to vulnerable populations: a growing global problem. Environ. Health Perspect. 2015, 10.1289/ehp.1509699.
29. Hornung R.W., Lanphear B.P., Dietrich K.N. Age of greatest susceptibility to childhood lead exposure: a new statistical approach. Environ. Health Perspect. 2009, 117:1309-1312.
30. Hotter G., Fels L.M., Closa D., Rosello J., Stolte H., Gelpi E. Altered levels of urinary prostanoids in lead-exposed workers. Toxicol. Lett. 1995, 77:309-312.
31. Hotz P., Buchet J.P., Bernard A., Lison D., Lauwerys R. Renal effects of low-level environmental cadmium exposure: 5-year follow-up of a subcohort from the Cadmibel study. Lancet 1999, 354:1508-1513.
32. Houston M.C. The role of mercury and cadmium heavy metals in vascular disease, hypertension, coronary heart disease, and myocardial infarction. Altern. Ther. Health Med. 2007, 13:S128-S133.
33. Huo X., Peng L., Xu X., Zheng L., Qiu B., Qi Z., Zhang B., Han D., Piao Z. Elevated blood lead levels of children in Guiyu, an electronic waste recycling town in China. Environ. Health Perspect. 2007, 115:1113-1117.
34. James K.A., Meliker J.R. Environmental cadmium exposure and osteoporosis: a review. Int. J. Public Health 2013, 58:737-745.
35. Järup L. Hazards of heavy metal contamination. Br. Med. Bull. 2003, 68:167-182.
36. Järup L., Alfven T. Low level cadmium exposure, renal and bone effects-the OSCAR study. Biometals 2004, 17:505-509.
37. Järup L., Berglund M., Elinder C.G., Nordberg G., Vahter M. Health effects of cadmium exposure-a review of the literature and a risk estimate. Scand. J. Work Environ. Health 1998, 24(Suppl. 1):1-51.
38. Järup L., Hellstrom L., Alfven T., Carlsson M.D., Grubb A., Persson B., Pettersson C., Spang G., Schutz A., Elinder C.G. Low level exposure to cadmium and early kidney damage: the OSCAR study. Occup. Environ. Med. 2000, 57:668-672.
39. Johansson C., Castoldi A.F., Onishchenko N., Manzo L., Vahter M., Ceccatelli S. Neurobehavioural and molecular changes induced by methylmercury exposure during development. Neurotox. Res. 2007, 11:241-260.
40. Johansson L., Pellicciari C.E. Lead-induced changes in the stabilization of the mouse sperm chromatin. Toxicology 1988, 51:11-24.
41. Johri N., Jacquillet G., Unwin R. Heavy metal poisoning: the effects of cadmium on the kidney. Biometals 2010, 23:783-792.
42. Kaji T., Fujiwara Y., Hoshino M., Yamamoto C., Sakamoto M., Kozuka H. Inhibitory effect of lead on the proliferation of cultured vascular endothelial cells. Toxicology 1995, 95:87-92.
43. Kaji T., Suzuki M., Yamamoto C., Mishima A., Sakamoto M., Kozuka H. Severe damage of cultured vascular endothelial cell monolayer after simultaneous exposure to cadmium and lead. Arch. Environ. Contam. Toxicol. 1995, 28:168-172.
44. Kaji T., Yamamoto C., Sakamoto M. Effect of lead on the glycosaminoglycans metabolism of bovine aortic endothelial cells in culture. Toxicology 1991, 68:249-257.
45. Kampa M., Castanas E. Human health effects of air pollution. Environ. Pollut. 2008, 151:362-367.
46. Karmaus W., Brooks K.R., Nebe T., Witten J., Obi-Osius N., Kruse H. Immune function biomarkers in children exposed to lead and organochlorine compounds: a cross-sectional study. Environ. Health 2005, 4:5.
47. Kim S., Arora M., Fernandez C., Landero J., Caruso J., Chen A. Lead, mercury, and cadmium exposure and attention deficit hyperactivity disorder in children. Environ. Res. 2013, 126:105-110.
48. Kishimoto T., Oguri T., Ueda D., Tada M. Effect of lead on tube formation by cultured human vascular endothelial cells. Arch. Toxicol. 1995, 69:718-721.
49. Koedrith P., Kim H., Weon J.I., Seo Y.R. Toxicogenomic approaches for understanding molecular mechanisms of heavy metal mutagenicity and carcinogenicity. Int. J. Hyg. Environ. Health 2013, 216:587-598.
50. Lancranjan I., Popescu H.I., GAvanescu O., Klepsch I., Serbanescu M. Reproductive ability of workmen occupationally exposed to lead. Arch. Environ. Health 1975, 30:396-401.
51. Langford N., Ferner R. Toxicity of mercury. J. Hum. Hypertens. 1999, 13:651-656.
52. Lauwerys R., Bernard A., Buchet J.P., Roels H., Bruaux P., Claeys F., Ducoffre G., De Plaen P., Staessen J., Amery A., Et A. Does environmental exposure to cadmium represent a health risk? conclusions from the Cadmibel study. Acta Clin. Belg. 1991, 46:219-225.
53. Leung A.O., Duzgoren-Aydin N.S., Cheung K.C., Wong M.H. Heavy metals concentrations of surface dust from e-waste recycling and its human health implications in southeast China. Environ. Sci. Technol. 2008, 42:2674-2680.
54. Li S., Zhengyan Z., Rong L., Hanyun C. Decrease of CD4+ T-lymphocytes in children exposed to environmental lead. Biol. Trace Elem. Res. 2005, 105:19-25.
55. Li Y., Li M., Liu Y., Song G., Liu N. A microarray for microRNA profiling in spermatozoa from adult men living in an environmentally polluted site. Bull. Environ. Contam. Toxicol. 2012, 89:1111-1114.
56. Li Y., Xu X., Liu J., Wu K., Gu C., Shao G., Chen S., Chen G., Huo X. The hazard of chromium exposure to neonates in Guiyu of China. Sci. Total Environ. 2008, 403:99-104.
57. Li Y., Xu X., Wu K., Chen G., Liu J., Chen S., Gu C., Zhang B., Zheng L., Zheng M., Huo X. Monitoring of lead load and its effect on neonatal behavioral neurological assessment scores in Guiyu, an electronic waste recycling town in China. J. Environ. Monit. 2008, 10:1233-1238.
58. Lin S., Huo X., Zhang Q., Fan X., Du L., Xu X., Qiu S., Zhang Y., Wang Y., Gu J. Short placental telomere was associated with cadmium pollution in an electronic waste recycling town in China. PLoS One 2013, 8:e60815.
59. Liu J., Xu X., Wu K., Piao Z., Huang J., Guo Y., Li W., Zhang Y., Chen A., Huo X. Association between lead exposure from electronic waste recycling and child temperament alterations. Neurotoxicology 2011, 32:458-464.
60. Liu Q., Cao J., Li K.Q., Miao X.H., Li G., Fan F.Y., Zhao Y.C. Chromosomal aberrations and DNA damage in human populations exposed to the processing of electronics waste. Environ. Sci. Pollut. Res. Int. 2009, 16:329-338.
61. Liu W., Huo X., Liu D., Zeng X., Zhang Y., Xu X. S100β in heavy metal-related child attention-deficit hyperactivity disorder in an informal e-waste recycling area. Neurotoxicology 2014, 45:185-191.
62. Loghman-Adham M. Renal effects of environmental and occupational lead exposure. Environ. Health Perspect. 1997, 105:928-938.
63. Luo C., Liu C., Wang Y., Liu X., Li F., Zhang G., Li X. Heavy metal contamination in soils and vegetables near an e-waste processing site, South China. J. Hazard. Mater 2011, 186:481-490.
64. Lutz P.M., Wilson T.J., Ireland J., Jones A.L., Gorman J.S., Gale N.L., Johnson J.C., Hewett J.E. Elevated immunoglobulin E (IgE) levels in children with exposure to environmental lead. Toxicology 1999, 134:63-78.
65. Marques M., Millas I., Jimenez A., Garcia-Colis E., Rodriguez-Feo J.A., Velasco S., Barrientos A., Casado S., Lopez-Farre A. Alteration of the soluble guanylate cyclase system in the vascular wall of lead-induced hypertension in rats. J. Am. Soc. Nephrol. 2001, 12:2594-2600.
66. Miller T.E., Golemboski K.A., Ha R.S., Bunn T., Sanders F.S., Dietert R.R. Developmental exposure to lead causes persistent immunotoxicity in Fischer 344 rats. Toxicol. Sci. 1998, 42:129-135.
67. Minoia C., Apostoli P., Maranelli G., Baldi C., Pozzoli L., Capodaglio E. Urinary chromium levels in subjects living in two north Italy regions. Sci. Total Environ. 1988, 71:527-531.
68. Minoia C., Cavalleri A. Chromium in urine, serum and red blood cells in the biological monitoring of workers exposed to different chromium valency states. Sci. Total Environ. 1988, 71:323-327.
69. Molero L., Carrasco C., Marques M., Vaziri N.D., Mateos-Caceres P.J., Casado S., Macaya C., Barrientos A., Lopez-Farre A.J. Involvement of endothelium and endothelin-1 in lead-induced smooth muscle cell dysfunction in rats. Kidney Int. 2006, 69:685-690.
70. Navas-Acien A., Guallar E., Silbergeld E.K., Rothenberg S.J. Lead exposure and cardiovascular disease-a systematic review. Environ. Health Perspect. 2007, 115:472-482.
71. Nicoloff G., Angelova M., Christova I., Nikolov A., Alexiev A. Serum cobalt in children with essential hypertension. Am. J. Hum. Biol. 2006, 18:798-805.
72. Oishi H., Nakashima M., Totoki T., Tomokuni K. Chronic lead exposure may inhibit endothelium-dependent hyperpolarizing factor in rats. J. Cardiovasc. Pharmacol. 1996, 28:558-563.
73. Pant D., Joshi D., Upreti M.K., Kotnala R.K. Chemical and biological extraction of metals present in E waste: a hybrid technology. Waste Manag 2012, 32:979-990.
74. Park J.D., Zheng W. Human exposure and health effects of inorganic and elemental mercury. J. Prev. Med. Public Health 2012, 45:344-352.
75. Pocock S.J., Smith M., Baghurst P. Environmental lead and children's intelligence: a systematic review of the epidemiological evidence. BMJ 1994, 309:1189-1197.
76. Pugh S.P., Nriagu J.O. Lead poisoning and asthma among low-income and African American children in Saginaw, Michigan. Environ. Res. 2011, 111:81-86.
77. Ramesh B.B., Parande A.K., Ahmed B.C. Electrical and electronic waste: a global environmental problem. Waste Manag. Res. 2007, 25:307-318.
78. Razi C.H., Akin O., Harmanci K., Akin B., Renda R. Serum heavy metal and antioxidant element levels of children with recurrent wheezing. Allergol. Immunopathol. Madr. 2011, 39:85-89.
79. Robinson B.H. E-waste: an assessment of global production and environmental impacts. Sci. Total Environ. 2009, 408:183-191.
80. Rodriguez-Iturbe B., Sindhu R.K., Quiroz Y., Vaziri N.D. Chronic exposure to low doses of lead results in renal infiltration of immune cells, NF-kappaB activation, and overexpression of tubulointerstitial angiotensin II. Antioxid. Redox Signal 2005, 7:1269-1274.
81. Rom W.N. Effects of lead on the female and reproduction: a review. Mt. Sinai J. Med. 1976, 43:542-552.
82. Sallmen M., Lindbohm M.L., Nurminen M. Paternal exposure to lead and infertility. Epidemiology 2000, 11:148-152.
83. Schober S.E., Mirel L.B., Graubard B.I., Brody D.J., Flegal K.M. Blood lead levels and death from all causes, cardiovascular disease, and cancer: results from the NHANES III mortality study. Environ. Health Perspect. 2006, 114:1538-1541.
84. Sharifi A.M., Darabi R., Akbarloo N., Larijani B., Khoshbaten A. Investigation of circulatory and tissue ACE activity during development of lead-induced hypertension. Toxicol. Lett. 2004, 153:233-238.
85. Silbergeld E.K. Localization of metals: issues of importance to neurotoxicology of lead. Neurotoxicology 1983, 4:193-200.
86. Snyder J.E., Filipov N.M., Parsons P.J., Lawrence D.A. The efficiency of maternal transfer of lead and its influence on plasma IgE and splenic cellularity of mice. Toxicol. Sci. 2000, 57:87-94.
87. Sughis M., Penders J., Haufroid V., Nemery B., Nawrot T.S. Bone resorption and environmental exposure to cadmium in children: a cross-sectional study. Environ. Health 2011, 10:104.
88. Sun L., Hu J., Zhao Z., Li L., Cheng H. Influence of exposure to environmental lead on serum immunoglobulin in preschool children. Environ. Res. 2003, 92:124-128.
89. Tian L.L., Zhao Y.C., Wang X.C., Gu J.L., Sun Z.J., Zhang Y.L., Wang J.X. Effects of gestational cadmium exposure on pregnancy outcome and development in the offspring at age 4.5 years. Biol. Trace Elem. Res. 2009, 132:51-59.
90. Trasande L., Landrigan P.J., Schechter C. Public health and economic consequences of methyl mercury toxicity to the developing brain. Environ. Health Perspect. 2005, 113:590-596.
91. Tsao D.A., Yu H.S., Cheng J.T., Ho C.K., Chang H.R. The change of beta-adrenergic system in lead-induced hypertension. Toxicol. Appl. Pharmacol. 2000, 164:127-133.
92. Tsydenova O., Bengtsson M. Chemical hazards associated with treatment of waste electrical and electronic equipment. Waste Manag. 2011, 31:45-58.
93. Ueda D., Kishimoto T., Dekio S., Tada M. Inhibitory effect of lead on tube formation by cultured human vascular endothelial cells. Hum. Cell 1997, 10:283-291.
94. Valencia I., Castillo E.E., Chamorro G., Bobadilla R.A., Castillo C. Lead induces endothelium- and Ca2+-independent contraction in rat aortic rings. Pharmacol. Toxicol. 2001, 89:177-182.
95. Vamvakas S., Bittner D., Koster U. Enhanced expression of the protooncogenes c-myc and c-fos in normal and malignant renal growth. Toxicol. Lett. 1993, 67:161-172.
96. Vaziri N.D. Mechanisms of lead-induced hypertension and cardiovascular disease. Am. J. Physiol. Heart Circ. Physiol. 2008, 295:H454-H465.
97. Wang Y., Chen A., Dietrich K.N., Radcliffe J., Caldwell K.L., Rogan W.J. Postnatal exposure to methyl mercury and neuropsychological development in 7-year-old urban inner-city children exposed to lead in the United States. Child. Neuropsychol. 2013, 20:527-538.
98. Waterman S.J., El-Fawal H.A., Snyder C.A. Lead alters the immunogenicity of two neural proteins: a potential mechanism for the progression of lead-induced neurotoxicity. Environ. Health Perspect. 1994, 102:1052-1056.
99. Widmer R., Oswald-Krapf H., Sinha-Khetriwal D., Schnellmann M., Boni H. Global perspectives on e-waste. Environ. Impact Assess. Rev. 2005, 25:436-458.
100. Wildt D.E., Bush M., Howard J.G., O'Brien S.J., Meltzer D., Van Dyk A., Ebedes H., Brand D.J. Unique seminal quality in the South African cheetah and a comparative evaluation in the domestic cat. Biol. Reprod. 1983, 29:1019-1025.
101. Winder C. Lead, reproduction and development. Neurotoxicology 1993, 14:303-317.
102. Wong R.H., Kuo C.Y., Hsu M.L., Wang T.Y., Chang P.I., Wu T.H., Huang S. Increased levels of 8-hydroxy-2 -deoxyguanosine attributable to carcinogenic metal exposure among schoolchildren. Environ. Health Perspect. 2005, 113:1386-1390.
103. Wyrobek A.J., Bruce W.R. Chemical induction of sperm abnormalities in mice. Proc. Natl. Acad. Sci. U. S. A. 1975, 72:4425-4429.
104. Xu X., Chen X., Zhang J., Guo P., Fu T., Dai Y., Lin S.L., Huo X. Decreased blood hepatitis B surface antibody levels linked to e-waste lead exposure in preschool children. J. Hazard Mater 2015, 298:122-128.
105. Xu X., Liu J., Zeng X., Lu F., Chen A., Huo X. Elevated serum polybrominated diphenyl ethers and alteration of thyroid hormones in children from Guiyu, china. PLoS One 2014, 9:e113699.
106. Xu X., Yang H., Chen A., Zhou Y., Wu K., Liu J., Zhang Y., Huo X. Birth outcomes related to informal e-waste recycling in Guiyu, China. Reprod. Toxicol. 2012, 33:94-98.
107. Xu X., Yekeen T.A., Liu J., Zhuang B., Li W., Huo X. Chromium exposure among children from an electronic waste recycling town of China. Environ. Sci. Pollut. R. 2013, 22:1778-1785.
108. Xue M., Yang Y., Ruan J., Xu Z. Assessment of noise and heavy metals (Cr, Cu, Cd, Pb) in the ambience of the production line for recycling waste printed circuit boards. Environ. Sci. Technol. 2012, 46:494-499.
109. Yamamoto C., Miyamoto A., Sakamoto M., Kaji T., Kozuka H. Lead perturbs the regulation of spontaneous release of tissue plasminogen activator and plasminogen activator inhibitor-1 from vascular smooth muscle cells and fibroblasts in culture. Toxicology 1997, 117:153-161.
110. Yang H., Huo X., Yekeen T.A., Zheng Q., Zheng M., Xu X. Effects of lead and cadmium exposure from electronic waste on child physical growth. Environ. Sci. Pollut. Res. Int. 2013, 20:4441-4447.
111. Youness E.R., Mohammed N.A., Morsy F.A. Cadmium impact and osteoporosis: mechanism of action. Toxicol. Mech. Methods 2012, 22:560-567.
112. Yule W., Lansdown R., Millar I.B., Urbanowicz M.A. The relationship between blood lead concentrations, intelligence and attainment in a school population: a pilot study. Dev. Med. Child. Neurol. 1981, 23:567-576.
113. Zhang R., Xu C., Shen H., Tang Y., Meng J., Lu W., Wang X., Lou X., Song Y., Han G., Cai D., Ding G. Oxidative damage and immunotoxicity effect on people exposed to electronic waste. Wei Sheng Yan Jiu 2012, 41:199-203. (in Chinese).
114. Zhang K., Schnoor J.L., Zeng E.Y. E-waste recycling: where does it go from here?. Environ. Sci. Technol. 2012, 46:10861-10867.
115. Zhang Q., Zhou T., Xu X., Guo Y., Zhao Z., Zhu M., Li W., Yi D., Huo X. Downregulation of placental S100P is associated with cadmium exposure in Guiyu, an e-waste recycling town in China. Sci. Total Environ. 2011, 410-411:53-58.
116. Zheng G., Xu X., Li B., Wu K., Yekeen T.A., Huo X. Association between lung function in school children and exposure to three transition metals from an e-waste recycling area. J. Expo. Sci. Environ. Epidemiol. 2013, 23:67-72.
117. Zheng L., Wu K., Li Y., Qi Z., Han D., Zhang B., Gu C., Chen G., Liu J., Chen S., Xu X., Huo X. Blood lead and cadmium levels and relevant factors among children from an e-waste recycling town in China. Environ. Res. 2008, 108:15-20.