A truncated analogue of CCL2 mediates anti-fibrotic effects on murine fibroblasts independently of CCR2

Biochemical Pharmacology

Volumn 83, Issue 5, 2012, Pages 644-652

  Kalderén, Christina ^a,b   Forsgren, Margareta ^a   Karlström, Ulla ^a   Stefansson, Karin ^a   Svensson, Robert ^a   Berglund, Magnus M ^a   Palm, Gunnar ^a   Selander, Martin ^a   Sundbom, Maj ^a   Nilsson, Joakim ^a   Sjögren, Annelie ^a   Zachrisson, Kristina ^a   Gelius, Stefan Svensson ^a  

^a BIOVITRUM AB   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

7ND; CCL2; CCR2; Chemokine; Fibrosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; BLEOMYCIN; CALCIUM; CHEMOKINE RECEPTOR CCR2; COLLAGEN TYPE 1; FIBRONECTIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1 INHIBITOR; MONOCYTE CHEMOTACTIC PROTEIN 1 VARIANT 7ND; PROTEIN VARIANT; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING COMPETITION; CALCIUM TRANSPORT; CHEMOTAXIS; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LUNG FIBROSIS; MONOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

ACTINS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CELL LINE; CHEMOKINE CCL2; CLONING, MOLECULAR; CRICETINAE; FEMALE; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; RECEPTORS, CCR2; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 84856080961     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.12.001     Document Type: Article

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