Activation of Thromboxane A2 Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2) and Recruits Macrophages to Promote Invasion of Lung Cancer Cells

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Li, Xiuling ^a   Tai, Hsin Hsiung ^a  

^a University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX METALLOPROTEINASE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; THROMBOXANE A2 RECEPTOR; TRANSCRIPTION FACTOR SP1; VASCULOTROPIN; 7 (3 (3 HYDROXY 4 (4' IODOPHENOXY) 1 BUTENYL) 7 OXABICYCLO(2.2.1)HEPTAN 2 YL) 5 HEPTENOIC ACID; 7-(3-(3-HYDROXY-4-(4'-IODOPHENOXY)-1-BUTENYL)-7-OXABICYCLO(2.2.1)HEPTAN-2-YL)-5-HEPTENOIC ACID; FUSED HETEROCYCLIC RINGS; THROMBOXANE A2; UNSATURATED FATTY ACID; VASCULOTROPIN A;

ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL INVASION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MACROPHAGE; MCP 1 GENE; MMP GENE; PRECIPITATION; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; SUPERNATANT; VEGF GENE; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL MOTION; COCULTURE; CYTOLOGY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CCL2; COCULTURE TECHNIQUES; FATTY ACIDS, UNSATURATED; GENE EXPRESSION; HUMANS; LUNG NEOPLASMS; MACROPHAGES; MATRIX METALLOPROTEINASES; MICROSCOPY, FLUORESCENCE; NEOPLASM INVASIVENESS; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR; THROMBOXANE A2; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MLCS; MLOWN;

EID: 84872567380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054073     Document Type: Article

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