Transport of the coumarin metabolite 7-hydroxycoumarin glucuronide is mediated via multidrug resistance-associated proteins 3 and 4

Drug Metabolism and Disposition

Volumn 40, Issue 6, 2012, Pages 1076-1079

  Wittgen, Hanneke G M ^a   Van Den Heuvel, Jeroen J M W ^a   Van Den Broek, Petra H H ^a   Siissalo, Sanna ^b   Groothuis, Geny M M ^b   De Graaf, Inge A M ^b   Koenderink, Jan B ^a   Russel, Frans G M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; COUMARIN; COUMARIN DERIVATIVE; DRUG METABOLITE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; UMBELLIFERONE; UMBELLIFERONE GLUCURONIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG EXCRETION; DRUG STRUCTURE; DRUG TRANSPORT; DRUG UPTAKE; EMBRYO; HUMAN; HUMAN CELL; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSPORT KINETICS; URINARY EXCRETION;

BIOLOGICAL TRANSPORT, ACTIVE; COUMARINS; HEK293 CELLS; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; UMBELLIFERONES;

EID: 84862067163     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.044438     Document Type: Article

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