Establishment of optimized MDCK cell lines for reliable efflux transport studies

Journal of Pharmaceutical Sciences

Volumn 103, Issue 4, 2014, Pages 1298-1304

  Gartzke, Dominik ^a   Fricker, Gert ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

ABC transporter; bidirectional transport assays; Cell lines; homogenous population; MDCK; P glycoprotein; PCR

Indexed keywords

DIGOXIN; MULTIDRUG RESISTANCE PROTEIN 1; QUINIDINE; VINBLASTINE;

ANIMAL CELL; ARTICLE; CALCEIN-AM ASSAY; CELL CLONE; CONTROLLED STUDY; DRUG TRANSPORT; FLUORESCENCE ACTIVATED CELL SORTING; GENE; MDCK CELL; MDR1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RELIABILITY; WESTERN BLOTTING; WILD TYPE;

ABC TRANSPORTER; BIDIRECTIONAL TRANSPORT ASSAYS; CELL LINES; HOMOGENOUS POPULATION; MDCK; P-GLYCOPROTEIN; PCR;

ANIMALS; BIOLOGICAL TRANSPORT; BIOLOGICAL TRANSPORT, ACTIVE; DIGOXIN; DOGS; FLOW CYTOMETRY; FLUORESCEINS; GENE EXPRESSION; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; P-GLYCOPROTEIN; QUINIDINE; TRANSFECTION; VINBLASTINE;

EID: 84896388709     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23901     Document Type: Article

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