Antiproliferation of Cryptocarya concinna-derived cryptocaryone against oral cancer cells involving apoptosis, oxidative stress, and DNA damage

BMC Complementary and Alternative Medicine

Volumn 16, Issue 1, 2016, Pages

  Chang, Hsun Shuo ^a   Tang, Jen Yang ^b,c,d   Yen, Ching Yu ^e,f   Huang, Hurng Wern ^g   Wu, Chang Yi ^g   Chung, Yi An ^a   Wang, Hui Ru ^a   Chen, Ih Sheng ^a   Huang, Ming Yii ^b,c   Chang, Hsueh Wei ^a,c,g  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d KAOHSIUNG MUNICIPAL TA TUNG HOSPITAL   (Taiwan)

^e CHI MEI MEDICAL CENTER   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^g NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Cryptocarya concinna; Cryptocaryone; Oral cancer; Oxidative stress; H2AX

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 4; CASPASE 5; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; CRYPTOCARYA CONCINNA DERIVED CRYPTOCARYONE; HISTONE H2AX; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOCORTIN 5; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CRYPTOCARYONE; PYRONE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL KILLING; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYPTOCARYA; CRYPTOCARYA CONCINNA; DNA DAMAGE; DRUG MECHANISM; ENZYME ACTIVITY; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC50; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUTH CANCER; ORAL CANCER CELL LINE; OXIDATIVE STRESS; STAINING; CELL PROLIFERATION; CHEMISTRY; MOUTH NEOPLASMS; PHYTOTHERAPY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYPTOCARYA; DNA DAMAGE; HUMANS; MOUTH NEOPLASMS; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PYRONES;

EID: 84960094148     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1073-5     Document Type: Article

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