7′,8′-Dihydroobolactone, a typanocidal α-pyrone from the rainforest tree Cryptocarya obovata

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 14, 2010, Pages 4057-4059

  Davis, Rohan A ^a   Demirkiran, Ozlem ^b   Sykes, Melissa L ^a   Avery, Vicky M ^a   Suraweera, Lekha ^a   Fechner, Gregory A ^a   Quinn, Ronald J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b TRAKYA UNIVERSITY   (Turkey)

Author keywords

7 ,8 Dihydroobolactone; A549; Antitrypanosomal; Cryptocarya obovata; HEK293; HeLa; MCF 7; Trypanosoma brucei brucei

Indexed keywords

2 PYRONE DERIVATIVE; 4',7 DI O METHYL NARINGENIN; 7 O METHYL NARINGENIN; 7',8' DIHYDROOBOLACTONE; ANTIPROTOZOAL AGENT; ANTITRYPANOSOMAL AGENT; OBOLACTONE; PSORALEN; UNCLASSIFIED DRUG; 7',8'-DIHYDROOBOLACTONE; LACTONE; PYRONE DERIVATIVE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CRYPTOCARYA; CRYPTOCARYA OBOVATA; CYTOTOXICITY; DRUG INHIBITION; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; NONHUMAN; PLANT LEAF; PROTON NUCLEAR MAGNETIC RESONANCE; RAIN FOREST; TRYPANOSOMA BRUCEI; CHEMISTRY; ISOLATION AND PURIFICATION; TUMOR CELL LINE;

CRYPTOCARYA OBOVATA; TRYPANOSOMA BRUCEI BRUCEI;

CELL LINE, TUMOR; HUMANS; LACTONES; PYRONES; TRYPANOCIDAL AGENTS;

EID: 77953871828     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.05.091     Document Type: Article

References (16)

1. World Health Organisation website, .
2. Sanderson L., Khan A., and Thomas S. Antimicrob. Agents Chemother. 51 (2007) 3136
3. Matovu E., Stewart M.L., Geiser F., Brun R., Maser P., Wallace L.J., Burchmore R.J., Enyaru J.C., Barrett M.P., Kaminsky R., Seebeck T., and de Koning H.P. Eukaryot. Cell 2 (2003) 1003
4. Buchanan M.S., Davis R.A., Duffy S., Avery V.M., and Quinn R.J. J. Nat. Prod. 72 (2009) 1541
5. Davis R.A., Duffy S., Avery V.M., Camp D., Hooper J.N.A., and Quinn R.J. Tetrahedron Lett. 51 (2010) 583
6. Mueller D., Davis R.A., Duffy S., Avery V.M., Camp D., and Quinn R.J. J. Nat. Prod. 72 (2009) 1538
7. Feng Y., Davis R.A., Sykes M.L., Avery V.M., Carroll A.R., Camp D., and Quinn R.J. Tetrahedron Lett. 51 (2010) 2477
8. Sykes M.L., and Avery V.M. Am. J. Trop. Med. Hyg. 81 (2009) 665
9. Pink R., Hudson A., Mouriès M.-A., and Bendig M. Nat. Rev. Drug Disc. 4 (2005) 727
10. Dumontet V., Van Hung N., Adeline M.-T., Riche C., Chiaroni A., Sevenet T., and Gueritte F. J. Nat. Prod. 67 (2004) 858
11. Masuda T., Takasugi M., and Anetai M. Phytochemistry 47 (1997) 13
12. Rossi M.H., Yoshida M., and Maia J.G.S. Phytochemistry 45 (1997) 1263
13. Perry N.B., and Foster L.M. Planta Med. 60 (1994) 491
14. + requires 313.1434).
15. Drewes S.E., Horn M.M., Ramesar N.S., Ferreira D., Nel R.J.J., and Hutchings A. Phytochemistry 49 (1998) 1683
16. Dictionary of Natural Products on DVD, version 18.2., Chapman and Hall/CRC Press: London, UK, 2009.