Development of an aptasensor for electrochemical detection of exosomes

Methods

Volumn 97, Issue , 2016, Pages 88-93

  Zhou, Qing ^a   Rahimian, Ali ^a   Son, Kyungjin ^a   Shin, Dong Sik ^a,b   Patel, Tushar ^c   Revzin, Alexander ^a  

^a University of California   (United States)

^b Sookmyung Women's University   (South Korea)

^c MAYO CLINIC   (United States)

Author keywords

Aptamer; Aptasensor; CD63; Electrochemical biosensor; Exosome detection

Indexed keywords

CD63 ANTIGEN; GOLD; MEMBRANE PROTEIN; APTAMER; CD63 PROTEIN, HUMAN; PROTEIN BINDING;

ANTIGEN SPECIFICITY; APTASENSOR; ARTICLE; BIOSENSOR; ELECTROCHEMICAL DETECTION; ELECTRODE; EXOSOME; IMMUNOASSAY; INTERMETHOD COMPARISON; LIMIT OF DETECTION; MICROFLUIDIC ANALYSIS; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; CHEMISTRY; ELECTROCHEMICAL ANALYSIS; HEP-G2 CELL LINE; HUMAN; SENSITIVITY AND SPECIFICITY; SURFACE PLASMON RESONANCE;

ANTIGENS, CD63; APTAMERS, NUCLEOTIDE; ELECTROCHEMICAL TECHNIQUES; EXOSOMES; HEP G2 CELLS; HUMANS; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY; SURFACE PLASMON RESONANCE;

EID: 84959917356     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2015.10.012     Document Type: Article

References (28)

1. Thery C., Ostrowski M., Segura E. Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol. 2009, 9(8):581-593.
2. Thery C., Zitvogel L., Amigorena S. Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2002, 2(8):569-579.
3. Harding C., Heuser J., Stahl P. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J. Cell Biol. 1983, 97(2):329-339.
4. Vlassov A.V., Magdaleno S., Setterquist R., Conrad R. Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. Biochim. Biophys. Acta 2012, 1820(7):940-948.
5. Andre F., Schartz N.E., Chaput N., Flament C., Raposo G., Amigorena S., Angevin E., Zitvogel L. Tumor-derived exosomes: a new source of tumor rejection antigens. Vaccine 2002, 20(Suppl. 4):A28-A31.
6. Andre F., Schartz N.E., Movassagh M., Flament C., Pautier P., Morice P., Pomel C., Lhomme C., Escudier B., Le Chevalier T., Tursz T., Amigorena S., Raposo G., Angevin E., Zitvogel L. Malignant effusions and immunogenic tumour-derived exosomes. Lancet 2002, 360(9329):295-305.
7. Andre F., Escudier B., Angevin E., Tursz T., Zitvogel L. Exosomes for cancer immunotherapy. Ann. Oncol. 2004, 15(Suppl. 4):iv141-iv144.
8. Thakur B.K., Zhang H., Becker A., Matei I., Huang Y., Costa-Silva B., Zheng Y., Hoshino A., Brazier H., Xiang J., Williams C., Rodriguez-Barrueco R., Silva J.M., Zhang W., Hearn S., Elemento O., Paknejad N., Manova-Todorova K., Welte K., Bromberg J., Peinado H., Lyden D. Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell Res. 2014, 24(6):766-769.
9. Shao H., Chung J., Balaj L., Charest A., Bigner D.D., Carter B.S., Hochberg F.H., Breakefield X.O., Weissleder R., Lee H. Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nat. Med. 2012, 18(12):1835-1840.
10. van der Pol E., Boing A.N., Harrison P., Sturk A., Nieuwland R. Classification, functions, and clinical relevance of extracellular vesicles. Pharmacol. Rev. 2012, 64(3):676-705.
11. Mathias R.A., Lim J.W., Ji H., Simpson R.J. Isolation of extracellular membranous vesicles for proteomic analysis. Methods Mol. Biol. 2009, 528:227-242.
12. Thery C., Amigorena S., Raposo G., Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr. Protoc. Cell Biol. 2006, Chapter 3: p. Unit 3 22.
13. Zhou H., Yuen P.S., Pisitkun T., Gonzales P.A., Yasuda H., Dear J.W., Gross P., Knepper M.A., Star R.A. Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery. Kidney Int. 2006, 69(8):1471-1476.
14. Ueda K., Ishikawa N., Tatsuguchi A., Saichi N., Fujii R., Nakagawa H. Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Sci. Rep. 2014, 4:6232.
15. Clayton A., Court J., Navabi H., Adams M., Mason M.D., Hobot J.A., Newman G.R., Jasani B. Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry. J. Immunol. Methods 2001, 247(1-2):163-174.
16. Im H., Shao H., Park Y.I., Peterson V.M., Castro C.M., Weissleder R., Lee H. Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor. Nat. Biotechnol. 2014, 32(5):490-495.
17. Zhu L., Wang K., Cui J., Liu H., Bu X., Ma H., Wang W., Gong H., Lausted C., Hood L., Yang G., Hu Z. Label-free quantitative detection of tumor-derived exosomes through surface plasmon resonance imaging. Anal. Chem. 2014, 86(17):8857-8864.
18. O'Sullivan C.K. Aptasensors - the future of biosensing?. Anal. Bioanal. Chem. 2002, 372:44-48.
19. Tan W.H., Wang K.M., Drake T.J. Molecular beacons. Curr. Opin. Chem. Biol. 2004, 8(5):547-553.
20. Xiao Y., Lubin A.A., Heeger A.J., Plaxco K.W. Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor. Angew. Chem. Int. Ed. 2005, 44(34):5456-5459.
21. Liu Y., Tuleouva N., Ramanculov E., Revzin A. Aptamer-based electrochemical biosensor for interferon gamma detection. Anal. Chem. 2010, 82(19):8131-8136.
22. Liu Y., Yan J., Howland M.C., Kwa T., Revzin A. Micropatterned aptasensors for continuous monitoring of cytokine release from human leukocytes. Anal. Chem. 2011, 83(21):8286-8292.
23. Liu Y., Zhou Q., Revzin A. An aptasensor for electrochemical detection of tumor necrosis factor in human blood. Analyst 2013, 138(15):4321-4326.
24. Matharu Z., Patel D., Gao Y., Haque A., Zhou Q., Revzin A. Detecting transforming growth factor-beta release from liver cells using an aptasensor integrated with microfluidics. Anal. Chem. 2014, 86(17):8865-8872.
25. Steel A.B., Herne T.M., Tarlov M.J. Electrochemical quantitation of DNA immobilized on gold. Anal. Chem. 1998, 70(22):4670-4677.
26. Herne T.M., Tarlov M.J. Characterization of DNA probes immobilized on gold surfaces. J. Am. Chem. Soc. 1997, 119(38):8916-8920.
27. Xiao Y., Lai R.Y., Plaxco K.W. Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing. Nat. Protoc. 2007, 2(11):2875-2880.
28. White R.J., Phares N., Lubin A.A., Xiao Y., Plaxco K.W. Optimization of electrochemical aptamer-based sensors via optimization of probe packing density and surface chemistry. Langmuir 2008, 24(18):10513-10518.