메뉴 건너뛰기




Volumn 71, Issue 2, 2016, Pages 403-412

Human oligopeptide transporter 2 (PEPT2) mediates cellular uptake of polymyxins

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; COLISTIN; FLUORESCENT DYE; GLYCYLSARCOSINE; GLYCYLSARCOSINE H 3; MIPS 9541; PEPTIDE TRANSPORTER 2; POLYMYXIN B; POLYMYXIN B1 H 3; POLYMYXIN DERIVATIVE; SOLUTE CARRIER TRANSPORTER; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; COTRANSPORTER; HYDROGEN-COUPLED OLIGOPEPTIDE TRANSPORTER PEPT2; POLYMYXIN;

EID: 84959906638     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv340     Document Type: Article
Times cited : (53)

References (75)
  • 1
    • 34248160010 scopus 로고    scopus 로고
    • Pandrug-resistant Gram-negative bacteria: the dawn of the post-antibiotic era?
    • Falagas ME, Bliziotis IA. Pandrug-resistant Gram-negative bacteria: the dawn of the post-antibiotic era? Int J Antimicrob Agents 2007; 29: 630-6.
    • (2007) Int J Antimicrob Agents , vol.29 , pp. 630-636
    • Falagas, M.E.1    Bliziotis, I.A.2
  • 2
    • 26444491047 scopus 로고    scopus 로고
    • Resistance to antibiotics: are we in the post-antibiotic era?
    • Alanis AJ. Resistance to antibiotics: are we in the post-antibiotic era? Arch Med Res 2005; 36: 697-705.
    • (2005) Arch Med Res , vol.36 , pp. 697-705
    • Alanis, A.J.1
  • 5
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: confronting the challenges of antibacterial discovery
    • Payne DJ, Gwynn MN, Holmes DJ et al. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev Drug Discov 2007; 6: 29-40.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3
  • 6
    • 84878293341 scopus 로고    scopus 로고
    • Pharmacology of polymyxins: new insights into an 'old' class of antibiotics
    • Velkov T, Roberts KD, Nation RL et al. Pharmacology of polymyxins: new insights into an 'old' class of antibiotics. Future Microbiol 2013; 8: 711-24.
    • (2013) Future Microbiol , vol.8 , pp. 711-724
    • Velkov, T.1    Roberts, K.D.2    Nation, R.L.3
  • 7
    • 84921024881 scopus 로고    scopus 로고
    • Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus
    • Nation RL, Li J, Cars O et al. Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus. Lancet Infect Dis 2015; 15: 225-34.
    • (2015) Lancet Infect Dis , vol.15 , pp. 225-234
    • Nation, R.L.1    Li, J.2    Cars, O.3
  • 8
    • 0032826448 scopus 로고    scopus 로고
    • Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant Gram-negative bacteria
    • Evans ME, Feola DJ, Rapp RP. Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant Gram-negative bacteria. Ann Pharmacother 1999; 33: 960-7.
    • (1999) Ann Pharmacother , vol.33 , pp. 960-967
    • Evans, M.E.1    Feola, D.J.2    Rapp, R.P.3
  • 9
    • 17644389620 scopus 로고    scopus 로고
    • Colistin: the revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections
    • Falagas ME, Kasiakou SK. Colistin: the revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections. Clin Infect Dis 2005; 40: 1333-41.
    • (2005) Clin Infect Dis , vol.40 , pp. 1333-1341
    • Falagas, M.E.1    Kasiakou, S.K.2
  • 10
    • 11144285626 scopus 로고    scopus 로고
    • Evaluation of colistin as an agent against multi-resistant Gram-negative bacteria
    • Li J, Nation RL, Milne RW et al. Evaluation of colistin as an agent against multi-resistant Gram-negative bacteria. Int J Antimicrob Agents 2005; 25: 11-25.
    • (2005) Int J Antimicrob Agents , vol.25 , pp. 11-25
    • Li, J.1    Nation, R.L.2    Milne, R.W.3
  • 11
    • 36849009383 scopus 로고
    • Aerosporin, an antibiotic produced by Bacillus aerosporus Greer
    • Ainsworth GC, Brown AM, Brownlee G. Aerosporin, an antibiotic produced by Bacillus aerosporus Greer. Nature 1947; 159: 263.
    • (1947) Nature , vol.159 , pp. 263
    • Ainsworth, G.C.1    Brown, A.M.2    Brownlee, G.3
  • 12
    • 0002004994 scopus 로고
    • Antibiotic activity of Bacillus polymyxa
    • Benedict RG, Langlykke AF. Antibiotic activity of Bacillus polymyxa. J Bacteriol 1947; 54: 24.
    • (1947) J Bacteriol , vol.54 , pp. 24
    • Benedict, R.G.1    Langlykke, A.F.2
  • 14
    • 33747362870 scopus 로고    scopus 로고
    • Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections
    • Li J, Nation RL, Turnidge JD et al. Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections. Lancet Infect Dis 2006; 6: 589-601.
    • (2006) Lancet Infect Dis , vol.6 , pp. 589-601
    • Li, J.1    Nation, R.L.2    Turnidge, J.D.3
  • 15
    • 0014077554 scopus 로고
    • Prevention by polymyxin B of endotoxin lethality in mice
    • Rifkind D. Prevention by polymyxin B of endotoxin lethality in mice. J Bacteriol 1967; 93: 1463-4.
    • (1967) J Bacteriol , vol.93 , pp. 1463-1464
    • Rifkind, D.1
  • 16
    • 84880939299 scopus 로고    scopus 로고
    • Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens
    • Sandri AM, Landersdorfer CB, Jacob J et al. Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens. Clin Infect Dis 2013; 57: 524-31.
    • (2013) Clin Infect Dis , vol.57 , pp. 524-531
    • Sandri, A.M.1    Landersdorfer, C.B.2    Jacob, J.3
  • 17
    • 84961288607 scopus 로고    scopus 로고
    • Significant accumulation of polymyxin in single renal tubular cells: a medicinal chemistry and triple correlative microscopy approach
    • Azad MA, Roberts KD, Yu HH et al. Significant accumulation of polymyxin in single renal tubular cells: a medicinal chemistry and triple correlative microscopy approach. Anal Chem 2015; 87: 1590-5.
    • (2015) Anal Chem , vol.87 , pp. 1590-1595
    • Azad, M.A.1    Roberts, K.D.2    Yu, H.H.3
  • 18
    • 0038673319 scopus 로고    scopus 로고
    • Use of high-performance liquid chromatography to study the pharmacokinetics of colistin sulfate in rats following intravenous administration
    • Li J, Milne RW, Nation RL et al. Use of high-performance liquid chromatography to study the pharmacokinetics of colistin sulfate in rats following intravenous administration. Antimicrob Agents Chemother 2003; 47: 1766-70.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1766-1770
    • Li, J.1    Milne, R.W.2    Nation, R.L.3
  • 19
    • 67649984938 scopus 로고    scopus 로고
    • Renal disposition of colistin in the isolated perfused rat kidney
    • Ma Z, Wang J, Nation RL et al. Renal disposition of colistin in the isolated perfused rat kidney. Antimicrob Agents Chemother 2009; 53: 2857-64.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2857-2864
    • Ma, Z.1    Wang, J.2    Nation, R.L.3
  • 20
    • 54249107903 scopus 로고    scopus 로고
    • Pharmacokinetics of intravenous polymyxin B in critically ill patients
    • Zavascki AP, Goldani LZ, Cao G et al. Pharmacokinetics of intravenous polymyxin B in critically ill patients. Clin Infect Dis 2008; 47: 1298-304.
    • (2008) Clin Infect Dis , vol.47 , pp. 1298-1304
    • Zavascki, A.P.1    Goldani, L.Z.2    Cao, G.3
  • 21
    • 84887469532 scopus 로고    scopus 로고
    • Megalin contributes to kidney accumulation and nephrotoxicity of colistin
    • Suzuki T, Yamaguchi H, Ogura J et al. Megalin contributes to kidney accumulation and nephrotoxicity of colistin. Antimicrob Agents Chemother 2013; 57: 6319-24.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 6319-6324
    • Suzuki, T.1    Yamaguchi, H.2    Ogura, J.3
  • 23
    • 84857092984 scopus 로고    scopus 로고
    • OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies
    • Roth M, Obaidat A, Hagenbuch B. OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies. Br J Pharmacol 2012; 165: 1260-87.
    • (2012) Br J Pharmacol , vol.165 , pp. 1260-1287
    • Roth, M.1    Obaidat, A.2    Hagenbuch, B.3
  • 24
    • 33845446759 scopus 로고    scopus 로고
    • Molecular insights into the structure-function relationship of organic anion transporters OATs
    • Zhou F, You G. Molecular insights into the structure-function relationship of organic anion transporters OATs. Pharm Res 2007; 24: 28-36.
    • (2007) Pharm Res , vol.24 , pp. 28-36
    • Zhou, F.1    You, G.2
  • 25
    • 84873329542 scopus 로고    scopus 로고
    • Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications
    • Smith DE, Clemencon B, Hediger MA. Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. Mol Aspects Med 2013; 34: 323-36.
    • (2013) Mol Aspects Med , vol.34 , pp. 323-336
    • Smith, D.E.1    Clemencon, B.2    Hediger, M.A.3
  • 26
    • 33644854071 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies
    • Nishimura M, Naito S. Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies. Drug Metab Pharmacokinet 2005; 20: 452-77.
    • (2005) Drug Metab Pharmacokinet , vol.20 , pp. 452-477
    • Nishimura, M.1    Naito, S.2
  • 27
    • 42249084123 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human solute carrier transporter superfamilies
    • Nishimura M, Naito S. Tissue-specific mRNA expression profiles of human solute carrier transporter superfamilies. Drug Metab Pharmacokinet 2008; 23: 22-44.
    • (2008) Drug Metab Pharmacokinet , vol.23 , pp. 22-44
    • Nishimura, M.1    Naito, S.2
  • 28
    • 0040699988 scopus 로고    scopus 로고
    • Intestinal transport of β-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux
    • Bretschneider B, Brandsch M, Neubert R. Intestinal transport of β-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux. Pharm Res 1999; 16: 55-61.
    • (1999) Pharm Res , vol.16 , pp. 55-61
    • Bretschneider, B.1    Brandsch, M.2    Neubert, R.3
  • 29
    • 9644252691 scopus 로고    scopus 로고
    • Interaction of 31 β-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1
    • Luckner P, Brandsch M. Interaction of 31 β-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. Eur J Pharm Biopharm 2005; 59: 17-24.
    • (2005) Eur J Pharm Biopharm , vol.59 , pp. 17-24
    • Luckner, P.1    Brandsch, M.2
  • 30
    • 0030424508 scopus 로고    scopus 로고
    • Transport characteristics of differently charged cephalosporin antibiotics in oocytes expressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2 cells
    • Wenzel U, Gebert I, Weintraut H et al. Transport characteristics of differently charged cephalosporin antibiotics in oocytes expressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2 cells. J Pharmacol Exp Ther 1996; 277: 831-9.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 831-839
    • Wenzel, U.1    Gebert, I.2    Weintraut, H.3
  • 31
    • 0028826927 scopus 로고
    • Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2
    • Ganapathy ME, Brandsch M, Prasad PD et al. Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. J Biol Chem 1995; 270: 25672-7.
    • (1995) J Biol Chem , vol.270 , pp. 25672-25677
    • Ganapathy, M.E.1    Brandsch, M.2    Prasad, P.D.3
  • 32
    • 84898970487 scopus 로고    scopus 로고
    • Probing the penetration of antimicrobial polymyxin lipopeptides into Gram-negative bacteria
    • Deris ZZ, Swarbrick JD, Roberts KD et al. Probing the penetration of antimicrobial polymyxin lipopeptides into Gram-negative bacteria. Bioconjug Chem 2014; 25: 750-60.
    • (2014) Bioconjug Chem , vol.25 , pp. 750-760
    • Deris, Z.Z.1    Swarbrick, J.D.2    Roberts, K.D.3
  • 33
    • 84908665940 scopus 로고    scopus 로고
    • Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human solute carrier transporters
    • Li Z, Wang K, Zheng J et al. Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human solute carrier transporters. Pharm Biol 2014; 52: 1510-7.
    • (2014) Pharm Biol , vol.52 , pp. 1510-1517
    • Li, Z.1    Wang, K.2    Zheng, J.3
  • 34
    • 84893787446 scopus 로고    scopus 로고
    • Interaction of the bioactive flavonol, icariin, with the essential human solute carrier transporters
    • Li Z, Cheung FS, Zheng J et al. Interaction of the bioactive flavonol, icariin, with the essential human solute carrier transporters. J Biochem Mol Toxicol 2014; 28: 91-7.
    • (2014) J Biochem Mol Toxicol , vol.28 , pp. 91-97
    • Li, Z.1    Cheung, F.S.2    Zheng, J.3
  • 35
    • 84907587051 scopus 로고    scopus 로고
    • Selective inhibition of human solute carrier transporters by multikinase inhibitors
    • Johnston RA, Rawling T, Chan T et al. Selective inhibition of human solute carrier transporters by multikinase inhibitors. Drug Metab Dispos 2014; 42: 1851-7.
    • (2014) Drug Metab Dispos , vol.42 , pp. 1851-1857
    • Johnston, R.A.1    Rawling, T.2    Chan, T.3
  • 36
    • 84885850124 scopus 로고    scopus 로고
    • The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters
    • Xu F, Li Z, Zheng J et al. The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters. J Pharm Sci 2013; 102: 4205-11.
    • (2013) J Pharm Sci , vol.102 , pp. 4205-4211
    • Xu, F.1    Li, Z.2    Zheng, J.3
  • 37
    • 75649122519 scopus 로고    scopus 로고
    • Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4)
    • Zhou F, Zhu L, Cui PH et al. Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4). Br J Pharmacol 2010; 159: 419-27.
    • (2010) Br J Pharmacol , vol.159 , pp. 419-427
    • Zhou, F.1    Zhu, L.2    Cui, P.H.3
  • 38
    • 84899650020 scopus 로고    scopus 로고
    • PDZK1 and NHERF1 regulate the function of human organic anion transporting polypeptide 1A2 (OATP1A2) by modulating its subcellular trafficking and stability
    • Zheng J, Chan T, Cheung FS et al. PDZK1 and NHERF1 regulate the function of human organic anion transporting polypeptide 1A2 (OATP1A2) by modulating its subcellular trafficking and stability. PLoS One 2014; 9: e94712.
    • (2014) PLoS One , vol.9
    • Zheng, J.1    Chan, T.2    Cheung, F.S.3
  • 39
    • 34547134693 scopus 로고    scopus 로고
    • Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells
    • Zhou F, Hong M, You G. Regulation of human organic anion transporter 4. by progesterone and protein kinase C in human placental BeWo cells. Am J Physiol Endocrinol Metab 2007; 293: E57-61.
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. E57-E61
    • Zhou, F.1    Hong, M.2    You, G.3
  • 40
    • 33644841714 scopus 로고    scopus 로고
    • Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells
    • Zhou F, Illsley NP, You G. Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells. Eur J Pharm Sci 2006; 27: 518-23.
    • (2006) Eur J Pharm Sci , vol.27 , pp. 518-523
    • Zhou, F.1    Illsley, N.P.2    You, G.3
  • 41
    • 79951962809 scopus 로고    scopus 로고
    • Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2
    • Zhou F, Lee AC, Krafczyk K et al. Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2. Br J Pharmacol 2011; 162: 1380-8.
    • (2011) Br J Pharmacol , vol.162 , pp. 1380-1388
    • Zhou, F.1    Lee, A.C.2    Krafczyk, K.3
  • 42
    • 39149097829 scopus 로고    scopus 로고
    • Comparison of the interaction of human organic anion transporter hOAT4 with PDZ proteins between kidney cells and placental cells
    • Zhou F, Xu W, Tanaka K et al. Comparison of the interaction of human organic anion transporter hOAT4 with PDZ proteins between kidney cells and placental cells. Pharm Res 2008; 25: 475-80.
    • (2008) Pharm Res , vol.25 , pp. 475-480
    • Zhou, F.1    Xu, W.2    Tanaka, K.3
  • 43
    • 84887998559 scopus 로고    scopus 로고
    • Functional analysis of novel polymorphisms in the human SLCO1A2 gene that encodes the transporter OATP1A2
    • Zhou F, Zheng J, Zhu L et al. Functional analysis of novel polymorphisms in the human SLCO1A2 gene that encodes the transporter OATP1A2. AAPS J 2013; 15: 1099-108.
    • (2013) AAPS J , vol.15 , pp. 1099-1108
    • Zhou, F.1    Zheng, J.2    Zhu, L.3
  • 44
    • 84920372546 scopus 로고    scopus 로고
    • Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control
    • Chan T, Zheng J, Zhu L et al. Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control. Mol Pharm 2015; 12: 111-9.
    • (2015) Mol Pharm , vol.12 , pp. 111-119
    • Chan, T.1    Zheng, J.2    Zhu, L.3
  • 45
    • 17644380567 scopus 로고    scopus 로고
    • Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7])
    • Kobayashi Y, Ohshiro N, Sakai R et al. Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]). J Pharm Pharmacol 2005; 57: 573-8.
    • (2005) J Pharm Pharmacol , vol.57 , pp. 573-578
    • Kobayashi, Y.1    Ohshiro, N.2    Sakai, R.3
  • 46
    • 3843123206 scopus 로고    scopus 로고
    • Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1
    • Hong M, Zhou F, You G. Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1. J Biol Chem 2004; 279: 31478-82.
    • (2004) J Biol Chem , vol.279 , pp. 31478-31482
    • Hong, M.1    Zhou, F.2    You, G.3
  • 47
    • 4644364576 scopus 로고    scopus 로고
    • Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans
    • Hirano M, Maeda K, Shitara Y et al. Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J Pharmacol Exp Ther 2004; 311: 139-46.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 139-146
    • Hirano, M.1    Maeda, K.2    Shitara, Y.3
  • 48
    • 77951247170 scopus 로고    scopus 로고
    • Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human α1-and α2-adrenoceptor subtypes
    • Amphoux A, Millan MJ, Cordi A et al. Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human α1-and α2-adrenoceptor subtypes. Eur J Pharmacol 2010; 634: 1-9.
    • (2010) Eur J Pharmacol , vol.634 , pp. 1-9
    • Amphoux, A.1    Millan, M.J.2    Cordi, A.3
  • 49
    • 84879705442 scopus 로고    scopus 로고
    • Functional analysis of novel variants in the organic cation/ergothioneine transporter 1 identified in Singapore populations
    • Toh DS, Cheung FS, MurrayM et al. Functional analysis of novel variants in the organic cation/ergothioneine transporter 1 identified in Singapore populations. Mol Pharm 2013; 10: 2509-16.
    • (2013) Mol Pharm , vol.10 , pp. 2509-2516
    • Toh, D.S.1    Cheung, F.S.2    Murray, M.3
  • 50
    • 80255136185 scopus 로고    scopus 로고
    • Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations
    • Toh DS, Murray M, Pern Tan K et al. Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations. Biochem Pharmacol 2011; 82: 1692-9.
    • (2011) Biochem Pharmacol , vol.82 , pp. 1692-1699
    • Toh, D.S.1    Murray, M.2    Pern Tan, K.3
  • 51
    • 84862784270 scopus 로고    scopus 로고
    • Construction, identification and application of HeLa cells stably transfected with human PEPT1 and PEPT2
    • Guo X, Meng Q, Liu Q et al. Construction, identification and application of HeLa cells stably transfected with human PEPT1 and PEPT2. Peptides 2012; 34: 395-403.
    • (2012) Peptides , vol.34 , pp. 395-403
    • Guo, X.1    Meng, Q.2    Liu, Q.3
  • 52
    • 33746146989 scopus 로고    scopus 로고
    • The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity
    • Noshiro R, Anzai N, Sakata T et al. The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity. Kidney Int 2006; 70: 275-82.
    • (2006) Kidney Int , vol.70 , pp. 275-282
    • Noshiro, R.1    Anzai, N.2    Sakata, T.3
  • 53
    • 25644448895 scopus 로고    scopus 로고
    • Role and relevance of peptide transporter 2(PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice
    • Ocheltree SM, Shen H, Hu Y et al. Role and relevance of peptide transporter 2(PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice. J Pharmacol Exp Ther 2005; 315: 240-7.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 240-247
    • Ocheltree, S.M.1    Shen, H.2    Hu, Y.3
  • 54
    • 84928910524 scopus 로고    scopus 로고
    • Major pathways of polymyxininduced apoptosis in rat kidney proximal tubular cells
    • Azad MA, Akter J, Rogers KL et al. Major pathways of polymyxininduced apoptosis in rat kidney proximal tubular cells. Antimicrob Agents Chemother 2015; 59: 2136-43.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 2136-2143
    • Azad, M.A.1    Akter, J.2    Rogers, K.L.3
  • 55
    • 84907916687 scopus 로고    scopus 로고
    • Measuring polymyxin uptake by renal tubular cells: is BODIPY-polymyxin B an appropriate probe?
    • Azad MA, Yun B, Roberts KD et al. Measuring polymyxin uptake by renal tubular cells: is BODIPY-polymyxin B an appropriate probe? Antimicrob Agents Chemother 2014; 58: 6337-8.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 6337-6338
    • Azad, M.A.1    Yun, B.2    Roberts, K.D.3
  • 56
    • 84860202021 scopus 로고    scopus 로고
    • Renal and neurological side effects of colistin in critically ill patients
    • Spapen H, Jacobs R, Van Gorp V et al. Renal and neurological side effects of colistin in critically ill patients. Ann Intensive Care 2011; 1: 14.
    • (2011) Ann Intensive Care , vol.1 , pp. 14
    • Spapen, H.1    Jacobs, R.2    Van Gorp, V.3
  • 57
    • 33744454666 scopus 로고    scopus 로고
    • Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa
    • Bergen PJ, Li J, Rayner CR et al. Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa. Antimicrob Agents Chemother 2006; 50: 1953-8.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1953-1958
    • Bergen, P.J.1    Li, J.2    Rayner, C.R.3
  • 58
    • 21644455416 scopus 로고    scopus 로고
    • Role of PEPT2 in the choroid plexus uptake of glycylsarcosine and 5-aminolevulinic acid: studies in wild-type and null mice
    • Ocheltree SM, Shen H, Hu Y et al. Role of PEPT2 in the choroid plexus uptake of glycylsarcosine and 5-aminolevulinic acid: studies in wild-type and null mice. Pharm Res 2004; 21: 1680-5.
    • (2004) Pharm Res , vol.21 , pp. 1680-1685
    • Ocheltree, S.M.1    Shen, H.2    Hu, Y.3
  • 59
    • 79959248672 scopus 로고    scopus 로고
    • Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients
    • Garonzik SM, Li J, Thamlikitkul V et al. Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients. Antimicrob Agents Chemother 2011; 55: 3284-94.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3284-3294
    • Garonzik, S.M.1    Li, J.2    Thamlikitkul, V.3
  • 60
    • 67749145541 scopus 로고    scopus 로고
    • Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by Gram-negative bacteria
    • Plachouras D, Karvanen M, Friberg LE et al. Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by Gram-negative bacteria. Antimicrob Agents Chemother 2009; 53: 3430-6.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3430-3436
    • Plachouras, D.1    Karvanen, M.2    Friberg, L.E.3
  • 61
    • 84868028805 scopus 로고    scopus 로고
    • Pharmacokinetics and renal disposition of polymyxin B in an animal model
    • Abdelraouf K, He J, Ledesma KR et al. Pharmacokinetics and renal disposition of polymyxin B in an animal model. Antimicrob Agents Chemother 2012; 56: 5724-7.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 5724-5727
    • Abdelraouf, K.1    He, J.2    Ledesma, K.R.3
  • 62
    • 84884261348 scopus 로고    scopus 로고
    • Pharmacokinetics of four different brands of colistimethate and formed colistin in rats
    • He H, Li JC, Nation RL et al. Pharmacokinetics of four different brands of colistimethate and formed colistin in rats. J Antimicrob Chemother 2013; 68: 2311-7.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2311-2317
    • He, H.1    Li, J.C.2    Nation, R.L.3
  • 63
    • 84889090433 scopus 로고    scopus 로고
    • Pharmacokinetics and efficacy of liposomal polymyxin B in a murine pneumonia model
    • He J, Abdelraouf K, Ledesma KR et al. Pharmacokinetics and efficacy of liposomal polymyxin B in a murine pneumonia model. Int J Antimicrob Agents 2013; 42: 559-64.
    • (2013) Int J Antimicrob Agents , vol.42 , pp. 559-564
    • He, J.1    Abdelraouf, K.2    Ledesma, K.R.3
  • 64
    • 84891509403 scopus 로고    scopus 로고
    • Pharmacokinetics of colistin methanesulfonate and formed colistin in end-stage renal disease patients receiving continuous ambulatory peritoneal dialysis
    • Koomanachai P, Landersdorfer CB, Chen G et al. Pharmacokinetics of colistin methanesulfonate and formed colistin in end-stage renal disease patients receiving continuous ambulatory peritoneal dialysis. Antimicrob Agents Chemother 2014; 58: 440-6.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 440-446
    • Koomanachai, P.1    Landersdorfer, C.B.2    Chen, G.3
  • 65
    • 0348149151 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis
    • Li J, Coulthard K, Milne R et al. Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis. J Antimicrob Chemother 2003; 52: 987-92.
    • (2003) J Antimicrob Chemother , vol.52 , pp. 987-992
    • Li, J.1    Coulthard, K.2    Milne, R.3
  • 66
    • 2442644015 scopus 로고    scopus 로고
    • Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate
    • Li J, Milne RW, Nation RL et al. Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate. J Antimicrob Chemother 2004; 53: 837-40.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 837-840
    • Li, J.1    Milne, R.W.2    Nation, R.L.3
  • 67
    • 84903212649 scopus 로고    scopus 로고
    • Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways
    • Dai C, Li J, Tang S et al. Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways. Antimicrob Agents Chemother 2014; 58: 4075-85.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4075-4085
    • Dai, C.1    Li, J.2    Tang, S.3
  • 69
    • 1242272750 scopus 로고    scopus 로고
    • The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology
    • Daniel H, Kottra G. The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflugers Arch 2004; 447: 610-8.
    • (2004) Pflugers Arch , vol.447 , pp. 610-618
    • Daniel, H.1    Kottra, G.2
  • 70
    • 33745807413 scopus 로고    scopus 로고
    • The renal type H+/peptide symporter PEPT2: structure-affinity relationships
    • Biegel A, Knutter I, Hartrodt B et al. The renal type H+/peptide symporter PEPT2: structure-affinity relationships. Amino Acids 2006; 31: 137-56.
    • (2006) Amino Acids , vol.31 , pp. 137-156
    • Biegel, A.1    Knutter, I.2    Hartrodt, B.3
  • 71
    • 33745868715 scopus 로고    scopus 로고
    • Structural requirements for the substrates of the H+/peptide cotransporter PEPT2 determined by three-dimensional quantitative structure-activity relationship analysis
    • Biegel A, Gebauer S, Brandsch M et al. Structural requirements for the substrates of the H+/peptide cotransporter PEPT2 determined by three-dimensional quantitative structure-activity relationship analysis. J Med Chem 2006; 49: 4286-96.
    • (2006) J Med Chem , vol.49 , pp. 4286-4296
    • Biegel, A.1    Gebauer, S.2    Brandsch, M.3
  • 72
    • 0032967296 scopus 로고    scopus 로고
    • Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney
    • Shen H, Smith DE, Yang T et al. Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney. Am J Physiol 1999; 276: F658-65.
    • (1999) Am J Physiol , vol.276 , pp. F658-F665
    • Shen, H.1    Smith, D.E.2    Yang, T.3
  • 73
    • 0031713192 scopus 로고    scopus 로고
    • Tubular localization and tissue distribution of peptide transporters in rat kidney
    • Smith DE, Pavlova A, Berger UV et al. Tubular localization and tissue distribution of peptide transporters in rat kidney. Pharm Res 1998; 15: 1244-9.
    • (1998) Pharm Res , vol.15 , pp. 1244-1249
    • Smith, D.E.1    Pavlova, A.2    Berger, U.V.3
  • 74
    • 84962464696 scopus 로고    scopus 로고
    • Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter
    • Doring F, Will J, Amasheh S et al. Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter. J Biol Chem 1998; 273: 23211-8.
    • (1998) J Biol Chem , vol.273 , pp. 23211-23218
    • Doring, F.1    Will, J.2    Amasheh, S.3
  • 75
    • 73949154997 scopus 로고    scopus 로고
    • Pharmacokinetics of novel antimicrobial cationic peptides NAB 7061 and NAB 739 in rats following intravenous administration
    • Ali FE, Cao G, Poudyal A et al. Pharmacokinetics of novel antimicrobial cationic peptides NAB 7061 and NAB 739 in rats following intravenous administration. J Antimicrob Chemother 2009; 64: 1067-70.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 1067-1070
    • Ali, F.E.1    Cao, G.2    Poudyal, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.