Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 7, 2014, Pages 4075-4085

  Dai, Chongshan ^a   Li, Jichang ^c   Tang, Shusheng ^a   Li, Jian ^b   Xiao, Xilong ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b MONASH UNIVERSITY   (Australia)

^c NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACTIVATING TRANSCRIPTION FACTOR 6; BECLIN 1; BIOLOGICAL MARKER; CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; CATALASE; COLISTIN; CREATININE; CYCLIN DEPENDENT KINASE 2; CYTOCHROME C; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LIGHT CHAIN 3 BETA; MALONALDEHYDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; 8-OXO-7-HYDRODEOXYGUANOSINE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; DEATH RECEPTOR; DEOXYGUANOSINE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE;

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; KIDNEY FUNCTION; MITOCHONDRION; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; BLOOD; DRUG EFFECTS; KIDNEY; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BIOMARKERS; BLOOD UREA NITROGEN; CASPASE 3; CASPASE 8; CASPASE 9; CATALASE; COLISTIN; CREATININE; DEOXYGUANOSINE; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FEMALE; KIDNEY; MALONDIALDEHYDE; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, DEATH DOMAIN; SUPEROXIDE DISMUTASE;

EID: 84903212649     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00070-14     Document Type: Article

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