메뉴 건너뛰기




Volumn 10, Issue 7, 2013, Pages 2509-2516

Functional analysis of novel variants in the organic cation/ergothioneine transporter 1 identified in singapore populations

Author keywords

human organic cation ergothioneine transporter 1; l ergothioneine; single nucleotide polymorphisms; SLC22A4; transporter function

Indexed keywords

HUMAN ORGANIC CATION ERGOTHIONEINE TRANSPORTER 1; ISOPROTEIN; ORGANIC CATION TRANSPORTER 1; PROTEIN VARIANT; THIONEINE; UNCLASSIFIED DRUG;

EID: 84879705442     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400193r     Document Type: Article
Times cited : (24)

References (45)
  • 2
    • 65249139907 scopus 로고    scopus 로고
    • Analysis and update of the human solute carrier (SLC) gene superfamily
    • He, L.; Vasiliou, K.; Nebert, D. W. Analysis and update of the human solute carrier (SLC) gene superfamily Hum. Genomics 2009, 3 (2) 195-206
    • (2009) Hum. Genomics , vol.3 , Issue.2 , pp. 195-206
    • He, L.1    Vasiliou, K.2    Nebert, D.W.3
  • 3
    • 0036952563 scopus 로고    scopus 로고
    • Catalog of 238 variations among six human genes encoding solute carriers (hSLCs) in the Japanese population
    • Saito, S.; Iida, A.; Sekine, A.; Ogawa, C.; Kawauchi, S.; Higuchi, S.; Nakamura, Y. Catalog of 238 variations among six human genes encoding solute carriers (hSLCs) in the Japanese population J. Hum. Genet. 2002, 47 (11) 576-584
    • (2002) J. Hum. Genet. , vol.47 , Issue.11 , pp. 576-584
    • Saito, S.1    Iida, A.2    Sekine, A.3    Ogawa, C.4    Kawauchi, S.5    Higuchi, S.6    Nakamura, Y.7
  • 4
    • 84860873283 scopus 로고    scopus 로고
    • The ergothioneine transporter controls and indicates ergothioneine activity - A review
    • Grundemann, D. The ergothioneine transporter controls and indicates ergothioneine activity-a review Prev. Med. 2012, 54 (Suppl), S71-S74
    • (2012) Prev. Med. , vol.54
    • Grundemann, D.1
  • 6
    • 34249943356 scopus 로고    scopus 로고
    • Polyspecific organic cation transporters: Structure, function, physiological roles, and biopharmaceutical implications
    • Koepsell, H.; Lips, K.; Volk, C. Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications Pharm. Res. 2007, 24 (7) 1227-1251
    • (2007) Pharm. Res. , vol.24 , Issue.7 , pp. 1227-1251
    • Koepsell, H.1    Lips, K.2    Volk, C.3
  • 7
    • 33744801418 scopus 로고    scopus 로고
    • Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria
    • Lamhonwah, A. M.; Tein, I. Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria Biochem. Biophys. Res. Commun. 2006, 345 (4) 1315-1325
    • (2006) Biochem. Biophys. Res. Commun. , vol.345 , Issue.4 , pp. 1315-1325
    • Lamhonwah, A.M.1    Tein, I.2
  • 8
    • 0031434178 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
    • Tamai, I.; Yabuuchi, H.; Nezu, J.; Sai, Y.; Oku, A.; Shimane, M.; Tsuji, A. Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1 FEBS Lett. 1997, 419 (1) 107-111
    • (1997) FEBS Lett. , vol.419 , Issue.1 , pp. 107-111
    • Tamai, I.1    Yabuuchi, H.2    Nezu, J.3    Sai, Y.4    Oku, A.5    Shimane, M.6    Tsuji, A.7
  • 9
    • 33847411467 scopus 로고    scopus 로고
    • Mechanism of the regulation of organic cation/carnitine transporter 1 (SLC22A4) by rheumatoid arthritis-associated transcriptional factor RUNX1 and inflammatory cytokines
    • Maeda, T.; Hirayama, M.; Kobayashi, D.; Miyazawa, K.; Tamai, I. Mechanism of the regulation of organic cation/carnitine transporter 1 (SLC22A4) by rheumatoid arthritis-associated transcriptional factor RUNX1 and inflammatory cytokines Drug Metab. Dispos. 2007, 35 (3) 394-401
    • (2007) Drug Metab. Dispos. , vol.35 , Issue.3 , pp. 394-401
    • Maeda, T.1    Hirayama, M.2    Kobayashi, D.3    Miyazawa, K.4    Tamai, I.5
  • 11
    • 63049092997 scopus 로고    scopus 로고
    • Skin cells and tissue are capable of using l -ergothioneine as an integral component of their antioxidant defense system
    • Markova, N. G.; Karaman-Jurukovska, N.; Dong, K. K.; Damaghi, N.; Smiles, K. A.; Yarosh, D. B. Skin cells and tissue are capable of using l -ergothioneine as an integral component of their antioxidant defense system Free Radical Biol. Med. 2009, 46 (8) 1168-1176
    • (2009) Free Radical Biol. Med. , vol.46 , Issue.8 , pp. 1168-1176
    • Markova, N.G.1    Karaman-Jurukovska, N.2    Dong, K.K.3    Damaghi, N.4    Smiles, K.A.5    Yarosh, D.B.6
  • 12
    • 84858153376 scopus 로고    scopus 로고
    • Ergothioneine; Antioxidant potential, physiological function and role in disease
    • Cheah, I. K.; Halliwell, B. Ergothioneine; antioxidant potential, physiological function and role in disease Biochim. Biophys. Acta 2012, 1822 (5) 784-793
    • (2012) Biochim. Biophys. Acta , vol.1822 , Issue.5 , pp. 784-793
    • Cheah, I.K.1    Halliwell, B.2
  • 16
    • 68249160805 scopus 로고    scopus 로고
    • The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel
    • McBride, B. F.; Yang, T.; Liu, K.; Urban, T. J.; Giacomini, K. M.; Kim, R. B.; Roden, D. M. The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel J. Cardiovasc. Pharmacol. 2009, 54 (1) 63-71
    • (2009) J. Cardiovasc. Pharmacol. , vol.54 , Issue.1 , pp. 63-71
    • McBride, B.F.1    Yang, T.2    Liu, K.3    Urban, T.J.4    Giacomini, K.M.5    Kim, R.B.6    Roden, D.M.7
  • 17
    • 71449106124 scopus 로고    scopus 로고
    • Genetic variations of the SLC22A4 gene in Chinese and Indian populations of Singapore
    • Toh, D. S.; Koo, S. H.; Limenta, L. M.; Yee, J. Y.; Murray, M.; Lee, E. J. Genetic variations of the SLC22A4 gene in Chinese and Indian populations of Singapore Drug Metab. Pharmacokinet. 2009, 24 (5) 475-481
    • (2009) Drug Metab. Pharmacokinet. , vol.24 , Issue.5 , pp. 475-481
    • Toh, D.S.1    Koo, S.H.2    Limenta, L.M.3    Yee, J.Y.4    Murray, M.5    Lee, E.J.6
  • 18
    • 68149160860 scopus 로고    scopus 로고
    • SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population
    • Feng, Y.; Zheng, P.; Zhao, H.; Wu, K. SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population J. Dig. Dis. 2009, 10 (3) 181-187
    • (2009) J. Dig. Dis. , vol.10 , Issue.3 , pp. 181-187
    • Feng, Y.1    Zheng, P.2    Zhao, H.3    Wu, K.4
  • 22
    • 58849164048 scopus 로고    scopus 로고
    • Increased ergothioneine tissue concentrations in carriers of the Crohn's disease risk-associated 503F variant of the organic cation transporter OCTN1
    • Taubert, D.; Jung, N.; Goeser, T.; Schomig, E. Increased ergothioneine tissue concentrations in carriers of the Crohn's disease risk-associated 503F variant of the organic cation transporter OCTN1 Gut 2009, 58 (2) 312-314
    • (2009) Gut , vol.58 , Issue.2 , pp. 312-314
    • Taubert, D.1    Jung, N.2    Goeser, T.3    Schomig, E.4
  • 24
    • 34548016273 scopus 로고    scopus 로고
    • Dietary sources and antioxidant effects of ergothioneine
    • Ey, J.; Schomig, E.; Taubert, D. Dietary sources and antioxidant effects of ergothioneine J. Agric. Food Chem. 2007, 55 (16) 6466-6474
    • (2007) J. Agric. Food Chem. , vol.55 , Issue.16 , pp. 6466-6474
    • Ey, J.1    Schomig, E.2    Taubert, D.3
  • 25
    • 84859505435 scopus 로고    scopus 로고
    • Preparation of culinary-medicinal king oyster mushroom Pleurotus eryngii -fermented products with high ergothioneine content and their taste quality
    • Chen, S. Y.; Ho, K. J.; Liang, C. H.; Tsai, C. H.; Huang, L. Y.; Mau, J. L. Preparation of culinary-medicinal king oyster mushroom Pleurotus eryngii -fermented products with high ergothioneine content and their taste quality Int. J. Med. Mushrooms 2012, 14 (1) 85-93
    • (2012) Int. J. Med. Mushrooms , vol.14 , Issue.1 , pp. 85-93
    • Chen, S.Y.1    Ho, K.J.2    Liang, C.H.3    Tsai, C.H.4    Huang, L.Y.5    Mau, J.L.6
  • 26
    • 34447282258 scopus 로고    scopus 로고
    • Quantification of polyphenols and ergothioneine in cultivated mushrooms and correlation to total antioxidant capacity
    • Dubost, N. J.; Ou, B.; Beelman, R. B. Quantification of polyphenols and ergothioneine in cultivated mushrooms and correlation to total antioxidant capacity Food Chem. 2007, 105, 727-735
    • (2007) Food Chem. , vol.105 , pp. 727-735
    • Dubost, N.J.1    Ou, B.2    Beelman, R.B.3
  • 27
    • 33847029934 scopus 로고    scopus 로고
    • Identification and quantification of ergothioneine in cultivated mushrooms using liquid chromatography-mass spectroscopy
    • Dubost, N. J.; Peterson, B. R.; Royse, D. J. Identification and quantification of ergothioneine in cultivated mushrooms using liquid chromatography-mass spectroscopy Int. J. Med. Mushrooms 2006, 8, 215-222
    • (2006) Int. J. Med. Mushrooms , vol.8 , pp. 215-222
    • Dubost, N.J.1    Peterson, B.R.2    Royse, D.J.3
  • 28
    • 84855723434 scopus 로고    scopus 로고
    • The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease
    • Pochini, L.; Scalise, M.; Galluccio, M.; Pani, G.; Siminovitch, K. A.; Indiveri, C. The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease Biochim. Biophys. Acta 2012, 1818 (3) 559-565
    • (2012) Biochim. Biophys. Acta , vol.1818 , Issue.3 , pp. 559-565
    • Pochini, L.1    Scalise, M.2    Galluccio, M.3    Pani, G.4    Siminovitch, K.A.5    Indiveri, C.6
  • 29
    • 80053286811 scopus 로고    scopus 로고
    • Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli
    • Pochini, L.; Scalise, M.; Galluccio, M.; Amelio, L.; Indiveri, C. Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli Biochem. J. 2011, 439 (2) 227-233
    • (2011) Biochem. J. , vol.439 , Issue.2 , pp. 227-233
    • Pochini, L.1    Scalise, M.2    Galluccio, M.3    Amelio, L.4    Indiveri, C.5
  • 31
    • 84862647180 scopus 로고    scopus 로고
    • Three-dimensional structures of membrane proteins from genomic sequencing
    • Hopf, T. A.; Colwell, L. J.; Sheridan, R.; Rost, B.; Sander, C.; Marks, D. S. Three-dimensional structures of membrane proteins from genomic sequencing Cell 2012, 149 (7) 1607-1621
    • (2012) Cell , vol.149 , Issue.7 , pp. 1607-1621
    • Hopf, T.A.1    Colwell, L.J.2    Sheridan, R.3    Rost, B.4    Sander, C.5    Marks, D.S.6
  • 34
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • Krogh, A.; Larsson, B.; von Heijne, G.; Sonnhammer, E. L. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes J. Mol. Biol. 2001, 305 (3) 567-580
    • (2001) J. Mol. Biol. , vol.305 , Issue.3 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    Von Heijne, G.3    Sonnhammer, E.L.4
  • 36
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D.; Higgins, D. G.; Gibson, T. J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Nucleic Acids Res. 1994, 22 (22) 4673-4680
    • (1994) Nucleic Acids Res. , vol.22 , Issue.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 38
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • Sali, A.; Blundell, T. L. Comparative protein modelling by satisfaction of spatial restraints J. Mol. Biol. 1993, 234 (3) 779-815
    • (1993) J. Mol. Biol. , vol.234 , Issue.3 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 39
    • 0033921479 scopus 로고    scopus 로고
    • Structure of renal organic anion and cation transporters
    • Burckhardt, G.; Wolff, N. A. Structure of renal organic anion and cation transporters Am. J. Physiol. Renal Physiol. 2000, 278 (6) F853-F866
    • (2000) Am. J. Physiol. Renal Physiol. , vol.278 , Issue.6
    • Burckhardt, G.1    Wolff, N.A.2
  • 40
    • 0016197604 scopus 로고
    • Amino acid difference formula to help explain protein evolution
    • Grantham, R. Amino acid difference formula to help explain protein evolution Science 1974, 185 (4154) 862-864
    • (1974) Science , vol.185 , Issue.4154 , pp. 862-864
    • Grantham, R.1
  • 41
    • 0021710490 scopus 로고
    • Nonrandomness of point mutation as reflected in nucleotide substitutions in pseudogenes and its evolutionary implications
    • Li, W. H.; Wu, C. I.; Luo, C. C. Nonrandomness of point mutation as reflected in nucleotide substitutions in pseudogenes and its evolutionary implications J. Mol. Evol. 1984, 21 (1) 58-71
    • (1984) J. Mol. Evol. , vol.21 , Issue.1 , pp. 58-71
    • Li, W.H.1    Wu, C.I.2    Luo, C.C.3
  • 43
    • 33646510996 scopus 로고    scopus 로고
    • Pharmacological rescue of carnitine transport in primary carnitine deficiency
    • Amat di San Filippo, C.; Pasquali, M.; Longo, N. Pharmacological rescue of carnitine transport in primary carnitine deficiency Hum. Mutat. 2006, 27 (6) 513-523
    • (2006) Hum. Mutat. , vol.27 , Issue.6 , pp. 513-523
    • Amat Di San Filippo, C.1    Pasquali, M.2    Longo, N.3
  • 44
    • 78650580445 scopus 로고    scopus 로고
    • Glycosylation of the OCTN2 carnitine transporter: Study of natural mutations identified in patients with primary carnitine deficiency
    • Filippo, C. A.; Ardon, O.; Longo, N. Glycosylation of the OCTN2 carnitine transporter: study of natural mutations identified in patients with primary carnitine deficiency Biochim. Biophys. Acta 2011, 1812 (3) 312-320
    • (2011) Biochim. Biophys. Acta , vol.1812 , Issue.3 , pp. 312-320
    • Filippo, C.A.1    Ardon, O.2    Longo, N.3
  • 45
    • 25444496731 scopus 로고    scopus 로고
    • Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn's disease
    • Taubert, D.; Grimberg, G.; Jung, N.; Rubbert, A.; Schomig, E. Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn's disease Gut 2005, 54 (10) 1505-1506
    • (2005) Gut , vol.54 , Issue.10 , pp. 1505-1506
    • Taubert, D.1    Grimberg, G.2    Jung, N.3    Rubbert, A.4    Schomig, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.