Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age

PLoS Genetics

Volumn 12, Issue 2, 2016, Pages

  Ivanov, Nikolay A ^a   Tao, Ran ^a   Chenoweth, Joshua G ^a   Brandtjen, Anna ^a   Mighdoll, Michelle I ^a   Genova, John D ^a   McKay, Ronald D ^a   Jia, Yankai ^a   Weinberger, Daniel R ^a,b   Kleinman, Joel E ^a   Hyde, Thomas M ^a,b   Jaffe, Andrew E ^a,c,d  

^a LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRANSCRIPTOME;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOPSY; CELL CULTURE; CELL DIFFERENTIATION; CELL POPULATION; CHILD; CONTROLLED STUDY; CPG ISLAND; DAUGHTER CELL; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENETICS; FIBROBLAST; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; LIFESPAN; MAJOR CLINICAL STUDY; MEMORY; MOSAICISM; PERSONALIZED MEDICINE; PLURIPOTENT STEM CELL; RATING SCALE; SCALP; SOMATIC MUTATION; STEM CELL; VERY ELDERLY; AGE; CYTOLOGY; GENETIC EPIGENESIS; MIDDLE AGED; PHYSIOLOGY; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FIBROBLASTS; HUMANS; INFANT; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SCALP; TRANSCRIPTOME; YOUNG ADULT;

EID: 84959898575     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005819     Document Type: Article

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