Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs

PLoS Genetics

Volumn 12, Issue 2, 2016, Pages

  Nagy, Zita ^a,b,c,d   Kalousi, Alkmini ^a,b,c,d   Furst, Audrey ^a,b,c,d   Koch, Marc ^a,b,c,d   Fischer, Benoit ^a,b,c,d   Soutoglou, Evi ^a,b,c,d  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA1A PROTEIN; DOUBLE STRANDED DNA; MEDIATOR OF DNA DAMAGE CHECKPOINT PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TANKYRASE; TANKYRASE 1; TANKYRASE 2; UNCLASSIFIED DRUG; BABAM1 PROTEIN, HUMAN; BRCA1 PROTEIN, HUMAN; DNA BINDING PROTEIN; MDC1 PROTEIN, HUMAN; NUCLEAR PROTEIN; RAD51 PROTEIN; RAD51 PROTEIN, HUMAN; RNF8 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TNKS PROTEIN, HUMAN; TNKS2 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE M PHASE; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; G2 PHASE CELL CYCLE CHECKPOINT; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; UPREGULATION; BINDING SITE; CELL LINE; GENETICS; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BINDING SITES; BRCA1 PROTEIN; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DNA-BINDING PROTEINS; HOMOLOGOUS RECOMBINATION; HUMANS; NUCLEAR PROTEINS; RAD51 RECOMBINASE; TANKYRASES; TRANS-ACTIVATORS;

EID: 84959894091     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005791     Document Type: Article

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