CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo

EMBO Reports

Volumn 17, Issue 3, 2016, Pages 338-348

  Kalebic, Nereo ^a   Taverna, Elena ^a   Tavano, Stefania ^a   Wong, Fong Kuan ^a   Suchold, Dana ^a   Winkler, Sylke ^a   Huttner, Wieland B ^a   Sarov, Mihail ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

CRISPR Cas9; in utero electroporation; microinjection; neural stem cell; neurogenesis

Indexed keywords

CRISPR ASSOCIATED PROTEIN; EOMESODERMIN; GUIDE RNA; PLASMID DNA; PROTEIN; RECOMBINANT PROTEIN; TIS21 PROTEIN; UNCLASSIFIED DRUG; BTG2 PROTEIN, MOUSE; IMMEDIATE EARLY PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN DEVELOPMENT; CELL FATE; CONTROLLED STUDY; CRISPR CAS SYSTEM; DAUGHTER CELL; ELECTROPORATION; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENE MUTATION; GENE TARGETING; IN VIVO STUDY; INDEL MUTATION; MICROINJECTION; MOUSE; NEOCORTEX; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; SLICE CULTURE; TELENCEPHALON; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; EMBRYOLOGY; EMBRYONIC STEM CELL; GENETICS; METABOLISM; PROCEDURES; SINGLE CELL ANALYSIS;

ANIMALS; CELLS, CULTURED; CRISPR-CAS SYSTEMS; ELECTROPORATION; EMBRYONIC STEM CELLS; GENE TARGETING; IMMEDIATE-EARLY PROTEINS; MICE; MICE, INBRED C57BL; NEURAL STEM CELLS; RNA, GUIDE; SINGLE-CELL ANALYSIS; TELENCEPHALON; TUMOR SUPPRESSOR PROTEINS;

EID: 84959558181     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201541715     Document Type: Article

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