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Volumn 159, Issue , 2016, Pages 73-85

Flaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovaries

Author keywords

Estrogen; Flaxseed; Hen; Ovarian cancer

Indexed keywords

2 HYDROXYESTRADIOL; 2 METHOXYESTRADIOL; AROMATASE; CATECHOL METHYLTRANSFERASE; CRK ASSOCIATED SUBSTRATE PROTEIN; CYTOCHROME P450 1A1; ENTERODIOL; ENTEROLACTONE; ESTROGEN; ESTROGEN RECEPTOR ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN C FOS; PROTEIN KINASE B BETA; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; TRANSCRIPTION FACTOR MAFF; 2-METHOXYESTRADIOL; AVIAN PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR; LINSEED OIL; PROTEIN KINASE B;

EID: 84959543526     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2016.02.028     Document Type: Article
Times cited : (30)

References (89)
  • 1
    • 84874959963 scopus 로고    scopus 로고
    • Flaxseed-a nutritional punch
    • P. Ganorkar, and R. Jain Flaxseed-a nutritional punch Int. Food Res. J. 20 2013 519 525
    • (2013) Int. Food Res. J. , vol.20 , pp. 519-525
    • Ganorkar, P.1    Jain, R.2
  • 2
    • 78649360374 scopus 로고    scopus 로고
    • Flaxseed lignans: Source, biosynthesis, metabolism, antioxidant activity, bio-active components, and health benefits
    • A. Touré, and X. Xueming Flaxseed lignans: source, biosynthesis, metabolism, antioxidant activity, bio-active components, and health benefits Compr. Rev. Food Sci. Food Saf. 9 2010 261 269
    • (2010) Compr. Rev. Food Sci. Food Saf. , vol.9 , pp. 261-269
    • Touré, A.1    Xueming, X.2
  • 4
    • 3042767902 scopus 로고    scopus 로고
    • Dietary long-chain n-3 fatty acids for the prevention of cancer: A review of potential mechanisms
    • S.C. Larsson, M. Kumlin, M. Ingelman-Sundberg, and A. Wolk Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms Am. J. Clin. Nutr. 79 2004 935 945
    • (2004) Am. J. Clin. Nutr. , vol.79 , pp. 935-945
    • Larsson, S.C.1    Kumlin, M.2    Ingelman-Sundberg, M.3    Wolk, A.4
  • 5
    • 0021861083 scopus 로고
    • Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function
    • T.H. Lee, R.L. Hoover, J.D. Williams, R.I. Sperling, J. Ravalese III, B.W. Spur, D.R. Robinson, E. Corey, R.A. Lewis, and K.F. Austen Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function New Engl. J. Med. 312 1985 1217 1224
    • (1985) New Engl. J. Med. , vol.312 , pp. 1217-1224
    • Lee, T.H.1    Hoover, R.L.2    Williams, J.D.3    Sperling, R.I.4    Ravalese, J.5    Spur, B.W.6    Robinson, D.R.7    Corey, E.8    Lewis, R.A.9    Austen, K.F.10
  • 6
    • 0002218208 scopus 로고    scopus 로고
    • Different doses of fish-oil fatty acid ingestion in active rheumatoid arthritis: A prospective study of clinical and immunological parameters, dietary ω3 and ω6 fatty acids
    • J.M. Kremer, D.A. Lawrence, and W. Jubiz Different doses of fish-oil fatty acid ingestion in active rheumatoid arthritis: a prospective study of clinical and immunological parameters, dietary ω3 and ω6 fatty acids Springer 2016 343 350
    • (2016) Springer , pp. 343-350
    • Kremer, J.M.1    Lawrence, D.A.2    Jubiz, W.3
  • 7
    • 0026039299 scopus 로고
    • Antiarrhythmic effects of fish oils
    • J.S. Charnock Antiarrhythmic effects of fish oils World Rev. Nutr. Diet 66 1991 278 291
    • (1991) World Rev. Nutr. Diet , vol.66 , pp. 278-291
    • Charnock, J.S.1
  • 8
    • 0022362713 scopus 로고
    • Enhancing effect of dietary supplementation with ω-3 fatty acids on plasma fibrinolysis in normal subjects
    • U. Barcelli, P. Glas-Greenwalt, and V.E. Pollak Enhancing effect of dietary supplementation with ω-3 fatty acids on plasma fibrinolysis in normal subjects Thromb. Res. 39 1985 307 312
    • (1985) Thromb. Res. , vol.39 , pp. 307-312
    • Barcelli, U.1    Glas-Greenwalt, P.2    Pollak, V.E.3
  • 10
    • 0021034240 scopus 로고
    • A comparison of the influence on plasma lipids and platelet function of supplements of ω3 and ω6 polyunsaturated fatty acids
    • T. Sanders, and M.C. Hochland A comparison of the influence on plasma lipids and platelet function of supplements of ω3 and ω6 polyunsaturated fatty acids Br. J. Nutr. 50 1983 521 529
    • (1983) Br. J. Nutr. , vol.50 , pp. 521-529
    • Sanders, T.1    Hochland, M.C.2
  • 11
    • 0031040390 scopus 로고    scopus 로고
    • Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed
    • K. Prasad Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed Mol. Cell. Biochem. 168 1997 117 123
    • (1997) Mol. Cell. Biochem. , vol.168 , pp. 117-123
    • Prasad, K.1
  • 12
    • 3242798960 scopus 로고    scopus 로고
    • Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor α (ERα) and ERβ in human cells
    • S.O. Mueller, S. Simon, K. Chae, M. Metzler, and K.S. Korach Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor α (ERα) and ERβ in human cells Toxicol. Sci. 80 2004 14 25
    • (2004) Toxicol. Sci. , vol.80 , pp. 14-25
    • Mueller, S.O.1    Simon, S.2    Chae, K.3    Metzler, M.4    Korach, K.S.5
  • 13
    • 46749104505 scopus 로고    scopus 로고
    • Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia
    • W. Zhang, X. Wang, Y. Liu, H. Tian, B. Flickinger, M.W. Empie, and S.Z. Sun Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia J. Med. Food 11 2008 207 214
    • (2008) J. Med. Food , vol.11 , pp. 207-214
    • Zhang, W.1    Wang, X.2    Liu, Y.3    Tian, H.4    Flickinger, B.5    Empie, M.W.6    Sun, S.Z.7
  • 14
    • 77955936575 scopus 로고    scopus 로고
    • Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men
    • S. Fukumitsu, K. Aida, H. Shimizu, and K. Toyoda Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men Nutr. Res. 30 2010 441 446
    • (2010) Nutr. Res. , vol.30 , pp. 441-446
    • Fukumitsu, S.1    Aida, K.2    Shimizu, H.3    Toyoda, K.4
  • 16
    • 18844389202 scopus 로고    scopus 로고
    • Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer
    • L.U. Thompson, J.M. Chen, T. Li, K. Strasser-Weippl, and P.E. Goss Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer Clin. Cancer Res. 11 2005 3828 3835
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3828-3835
    • Thompson, L.U.1    Chen, J.M.2    Li, T.3    Strasser-Weippl, K.4    Goss, P.E.5
  • 17
    • 84929773650 scopus 로고    scopus 로고
    • Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner
    • A. Dikshit, M.A. Gomes Filho, E. Eilati, S. McGee, C. Small, C. Gao, T. Klug, and D.B. Hales Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner Br. J. Nutr. 2015 1 12
    • (2015) Br. J. Nutr. , pp. 1-12
    • Dikshit, A.1    Gomes Filho, M.A.2    Eilati, E.3    McGee, S.4    Small, C.5    Gao, C.6    Klug, T.7    Hales, D.B.8
  • 19
    • 33847392879 scopus 로고    scopus 로고
    • Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo
    • M.B. Jungeström, L.U. Thompson, and C. Dabrosin Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo Clin. Cancer Res. 13 2007 1061 1067
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1061-1067
    • Jungeström, M.B.1    Thompson, L.U.2    Dabrosin, C.3
  • 20
    • 9344238812 scopus 로고    scopus 로고
    • Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice
    • J. Chen, E. Hui, T. Ip, and L.U. Thompson Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice Clin. Cancer Res. 10 2004 7703 7711
    • (2004) Clin. Cancer Res. , vol.10 , pp. 7703-7711
    • Chen, J.1    Hui, E.2    Ip, T.3    Thompson, L.U.4
  • 21
    • 0036966926 scopus 로고    scopus 로고
    • Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor
    • J. Chen, P.M. Stavro, and L.U. Thompson Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor Nutr. Cancer 43 2002 187 192
    • (2002) Nutr. Cancer , vol.43 , pp. 187-192
    • Chen, J.1    Stavro, P.M.2    Thompson, L.U.3
  • 23
    • 0034946423 scopus 로고    scopus 로고
    • Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: Exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features
    • W. Demark-Wahnefried, D.T. Price, T.J. Polascik, C.N. Robertson, E.E. Anderson, D.F. Paulson, P.J. Walther, M. Gannon, and R.T. Vollmer Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features Urology 58 2001 47 52
    • (2001) Urology , vol.58 , pp. 47-52
    • Demark-Wahnefried, W.1    Price, D.T.2    Polascik, T.J.3    Robertson, C.N.4    Anderson, E.E.5    Paulson, D.F.6    Walther, P.J.7    Gannon, M.8    Vollmer, R.T.9
  • 24
    • 0032570762 scopus 로고    scopus 로고
    • Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice
    • L. Yan, J.A. Yee, D. Li, M.H. McGuire, and L.U. Thompson Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice Cancer Lett. 124 1998 181 186
    • (1998) Cancer Lett. , vol.124 , pp. 181-186
    • Yan, L.1    Yee, J.A.2    Li, D.3    McGuire, M.H.4    Thompson, L.U.5
  • 25
    • 84882453783 scopus 로고    scopus 로고
    • Long term consumption of flaxseed enriched diet decreased ovarian cancer incidence and prostaglandin E2 in hens
    • E. Eilati, J.M. Bahr, and D.B. Hales Long term consumption of flaxseed enriched diet decreased ovarian cancer incidence and prostaglandin E2 in hens Gynecol. Oncol. 3 2013 620 628
    • (2013) Gynecol. Oncol. , vol.3 , pp. 620-628
    • Eilati, E.1    Bahr, J.M.2    Hales, D.B.3
  • 26
    • 77950256706 scopus 로고    scopus 로고
    • Decreased severity of ovarian cancer and increased survival in hens fed a flaxseed enriched diet for one year
    • K. Ansenberger, Y. Zhuge, C. Richards, A. Barua, J.L. Luborsky, J.M. Bahr, and D.B. Hales Decreased severity of ovarian cancer and increased survival in hens fed a flaxseed enriched diet for one year Gynecol. Oncol. 117 2010 341 347
    • (2010) Gynecol. Oncol. , vol.117 , pp. 341-347
    • Ansenberger, K.1    Zhuge, Y.2    Richards, C.3    Barua, A.4    Luborsky, J.L.5    Bahr, J.M.6    Hales, D.B.7
  • 28
    • 0034221273 scopus 로고    scopus 로고
    • Human requirement for N-3 polyunsaturated fatty acids
    • A. Simopoulos Human requirement for N-3 polyunsaturated fatty acids Poult. Sci. 79 2000 961 970
    • (2000) Poult. Sci. , vol.79 , pp. 961-970
    • Simopoulos, A.1
  • 29
    • 84886216107 scopus 로고    scopus 로고
    • Anti-inflammatory effects of fish oil in ovaries of laying hens target prostaglandin pathways
    • E. Eilati, C.C. Small, S.R. McGee, N.K. Kurrey, and D.B. Hales Anti-inflammatory effects of fish oil in ovaries of laying hens target prostaglandin pathways Lipids Health Dis. 12 2013 152
    • (2013) Lipids Health Dis. , vol.12 , pp. 152
    • Eilati, E.1    Small, C.C.2    McGee, S.R.3    Kurrey, N.K.4    Hales, D.B.5
  • 30
    • 67349287341 scopus 로고    scopus 로고
    • E-cadherin expression in ovarian cancer in the laying hen Gallus domesticus, compared to human ovarian cancer
    • K. Ansenberger, Y. Zhuge, J.A. Lagman, C. Richards, A. Barua, J.M. Bahr, and D.B. Hales E-cadherin expression in ovarian cancer in the laying hen Gallus domesticus, compared to human ovarian cancer Gynecol. Oncol. 113 2009 362 369
    • (2009) Gynecol. Oncol. , vol.113 , pp. 362-369
    • Ansenberger, K.1    Zhuge, Y.2    Lagman, J.A.3    Richards, C.4    Barua, A.5    Bahr, J.M.6    Hales, D.B.7
  • 31
    • 84907063579 scopus 로고    scopus 로고
    • Uncovering molecular events associated with the chemosuppressive effects of flaxseed: A microarray analysis of the laying hen model of ovarian cancer
    • K.H. Hales, S.C. Speckman, N.K. Kurrey, and D.B. Hales Uncovering molecular events associated with the chemosuppressive effects of flaxseed: a microarray analysis of the laying hen model of ovarian cancer BMC Genomics 15 2014 709
    • (2014) BMC Genomics , vol.15 , pp. 709
    • Hales, K.H.1    Speckman, S.C.2    Kurrey, N.K.3    Hales, D.B.4
  • 34
    • 84870677710 scopus 로고    scopus 로고
    • Age dependent increase in prostaglandin pathway coincides with onset of ovarian cancer in laying hens
    • E. Eilati, L. Pan, J.M. Bahr, and D.B. Hales Age dependent increase in prostaglandin pathway coincides with onset of ovarian cancer in laying hens Prostag. Leukotr. Ess. Fatty Acids 87 2012 177 184
    • (2012) Prostag. Leukotr. Ess. Fatty Acids , vol.87 , pp. 177-184
    • Eilati, E.1    Pan, L.2    Bahr, J.M.3    Hales, D.B.4
  • 36
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogensin and suppresses tumor growth
    • T. Fostis, Y. Zhang, M. Pepper, H. Adlercreutz, R. Montesano, P. Nawroth, and L. Schweigere The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogensin and suppresses tumor growth Nature 17 1994 237 239
    • (1994) Nature , vol.17 , pp. 237-239
    • Fostis, T.1    Zhang, Y.2    Pepper, M.3    Adlercreutz, H.4    Montesano, R.5    Nawroth, P.6    Schweigere, L.7
  • 39
    • 73949149189 scopus 로고    scopus 로고
    • Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity
    • Y.S. Chua, Y.L. Chua, and T. Hagen Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity Mol. Cancer Ther. 9 2010 224 235
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 224-235
    • Chua, Y.S.1    Chua, Y.L.2    Hagen, T.3
  • 40
    • 0000317180 scopus 로고    scopus 로고
    • Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?
    • B.T. Zhu, and A.H. Conney Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis? Cancer Res. 58 1998 2269 2277
    • (1998) Cancer Res. , vol.58 , pp. 2269-2277
    • Zhu, B.T.1    Conney, A.H.2
  • 41
    • 0029865150 scopus 로고    scopus 로고
    • 4-Hydroxylation of estrogens as marker of human mammary tumors
    • J.G. Liehr, and M.J. Ricci 4-Hydroxylation of estrogens as marker of human mammary tumors Proc. Natl. Acad. Sci. 93 1996 3294 3296
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 3294-3296
    • Liehr, J.G.1    Ricci, M.J.2
  • 42
    • 0022930321 scopus 로고
    • 16α-Hydroxylation of estradiol: A possible risk marker for Breast cancer
    • H. Bradlow, R. Hershcopf, C. Martucci, and J. Fishman 16α-Hydroxylation of estradiol: a possible risk marker for Breast cancer Ann. N.Y. Acad. Sci. 464 1986 138 151
    • (1986) Ann. N.Y. Acad. Sci. , vol.464 , pp. 138-151
    • Bradlow, H.1    Hershcopf, R.2    Martucci, C.3    Fishman, J.4
  • 44
    • 0030896509 scopus 로고    scopus 로고
    • Cell-specific regulation of human CYP1A1 and CYP1B1 genes
    • S. Kress, and W.F. Greenlee Cell-specific regulation of human CYP1A1 and CYP1B1 genes Cancer Res. 57 1997 1264 1269
    • (1997) Cancer Res. , vol.57 , pp. 1264-1269
    • Kress, S.1    Greenlee, W.F.2
  • 47
    • 0842303519 scopus 로고    scopus 로고
    • Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells
    • F. Frasca, G. Pandini, R. Vigneri, and I.D. Goldfine Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells Breast Dis. 17 2002 73 89
    • (2002) Breast Dis. , vol.17 , pp. 73-89
    • Frasca, F.1    Pandini, G.2    Vigneri, R.3    Goldfine, I.D.4
  • 48
    • 57149139395 scopus 로고    scopus 로고
    • Regulation of breast cancer metastasis by IGF signaling
    • D. Sachdev Regulation of breast cancer metastasis by IGF signaling J. Mammary Gland Biol. Neoplasia 13 2008 431 441
    • (2008) J. Mammary Gland Biol. Neoplasia , vol.13 , pp. 431-441
    • Sachdev, D.1
  • 50
    • 33846807433 scopus 로고    scopus 로고
    • Disrupting insulin-like growth factor signaling as a potential cancer therapy
    • D. Sachdev, and D. Yee Disrupting insulin-like growth factor signaling as a potential cancer therapy Mol. Cancer Ther. 6 2007 1 12
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1-12
    • Sachdev, D.1    Yee, D.2
  • 52
    • 0027239935 scopus 로고
    • Retinoic acid and estrogen modulation of insulin-like growth factor binding protein-4 gene expression and the estrogen receptor status of human breast carcinoma cells
    • M. Sheikh, Z. Shao, A. Hussain, J. Chen, C. Roberts, D. LeRoith, and J. Fontana Retinoic acid and estrogen modulation of insulin-like growth factor binding protein-4 gene expression and the estrogen receptor status of human breast carcinoma cells Biochem. Biophys. Res. Commun. 193 1993 1232 1238
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 1232-1238
    • Sheikh, M.1    Shao, Z.2    Hussain, A.3    Chen, J.4    Roberts, C.5    LeRoith, D.6    Fontana, J.7
  • 53
    • 0027496222 scopus 로고
    • Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media
    • S.E. Pratt, and M.N. Pollak Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media Cancer Res. 53 1993 5193 5198
    • (1993) Cancer Res. , vol.53 , pp. 5193-5198
    • Pratt, S.E.1    Pollak, M.N.2
  • 54
    • 33747603651 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein 2 and 5 are differentially regulated in ovarian cancer of different histologic types
    • H. Wang, D.G. Rosen, H. Wang, G.N. Fuller, W. Zhang, and J. Liu Insulin-like growth factor-binding protein 2 and 5 are differentially regulated in ovarian cancer of different histologic types Mod. Pathol. 19 2006 1149 1156
    • (2006) Mod. Pathol. , vol.19 , pp. 1149-1156
    • Wang, H.1    Rosen, D.G.2    Wang, H.3    Fuller, G.N.4    Zhang, W.5    Liu, J.6
  • 55
    • 84963625116 scopus 로고    scopus 로고
    • The role of Akt pathway signaling in glucose metabolism and metabolic oxidative stress, oxidative stress in cancerbiology and therapy
    • A.L. Simons, K.P. Orcutt, J.M. Madsen, P.M. Scarbrough, and D.R. Spitz The role of Akt pathway signaling in glucose metabolism and metabolic oxidative stress, oxidative stress in cancerbiology and therapy Springer 2012 21 46
    • (2012) Springer , pp. 21-46
    • Simons, A.L.1    Orcutt, K.P.2    Madsen, J.M.3    Scarbrough, P.M.4    Spitz, D.R.5
  • 56
    • 84908642100 scopus 로고    scopus 로고
    • PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: An update
    • A. Makker, M.M. Goel, and A.A. Mahdi PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an update J. Mol. Endocrinol. 3 2014 R103 R118
    • (2014) J. Mol. Endocrinol. , vol.3 , pp. R103-R118
    • Makker, A.1    Goel, M.M.2    Mahdi, A.A.3
  • 57
    • 84862777505 scopus 로고    scopus 로고
    • Clinical assessment of PTEN loss in endometrial carcinoma: Immunohistochemistry outperforms gene sequencing
    • B. Djordjevic, B.T. Hennessy, J. Li, B.A. Barkoh, R. Luthra, G.B. Mills, and R.R. Broaddus Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing Mod. Pathol. 25 2012 699 708
    • (2012) Mod. Pathol. , vol.25 , pp. 699-708
    • Djordjevic, B.1    Hennessy, B.T.2    Li, J.3    Barkoh, B.A.4    Luthra, R.5    Mills, G.B.6    Broaddus, R.R.7
  • 59
    • 27544433196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and ovarian function-implications for regulating steroidogenesis, differentiation, and tissue remodeling
    • C.M. Komar Peroxisome proliferator-activated receptors (PPARs) and ovarian function-implications for regulating steroidogenesis, differentiation, and tissue remodeling Reprod. Biol. Endocrinol. 3 2005 41
    • (2005) Reprod. Biol. Endocrinol. , vol.3 , pp. 41
    • Komar, C.M.1
  • 60
    • 81055144760 scopus 로고    scopus 로고
    • Adipocyte NCoR knockout decreases PPAR γ phosphorylation and enhances PPAR γ activity and insulin sensitivity
    • P. Li, W. Fan, J. Xu, M. Lu, H. Yamamoto, J. Auwerx, D.D. Sears, S. Talukdar, D. Oh, and A. Chen Adipocyte NCoR knockout decreases PPAR γ phosphorylation and enhances PPAR γ activity and insulin sensitivity Cell 147 2011 815 826
    • (2011) Cell , vol.147 , pp. 815-826
    • Li, P.1    Fan, W.2    Xu, J.3    Lu, M.4    Yamamoto, H.5    Auwerx, J.6    Sears, D.D.7    Talukdar, S.8    Oh, D.9    Chen, A.10
  • 62
    • 4344691786 scopus 로고    scopus 로고
    • Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor γ in epithelial ovarian tumours
    • A. Sakamoto, Y. Yokoyama, M. Umemoto, M. Futagami, T. Sakamoto, X. Bing, and H. Mizunuma Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor γ in epithelial ovarian tumours Br. J. Cancer 91 2004 633 638
    • (2004) Br. J. Cancer , vol.91 , pp. 633-638
    • Sakamoto, A.1    Yokoyama, Y.2    Umemoto, M.3    Futagami, M.4    Sakamoto, T.5    Bing, X.6    Mizunuma, H.7
  • 63
    • 22344434292 scopus 로고    scopus 로고
    • Nanomolar and micromolar effects of 15-deoxy-δ12, 14-prostaglandin J2 on amnion-derived WISH epithelial cells: Differential roles of peroxisome proliferator-activated receptors γ and δ and nuclear factor κb
    • E.B. Berry, J.A. Keelan, R.J. Helliwell, R.S. Gilmour, and M.D. Mitchell Nanomolar and micromolar effects of 15-deoxy-δ12, 14-prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors γ and δ and nuclear factor κB Mol. Pharmacol. 68 2005 169 178
    • (2005) Mol. Pharmacol. , vol.68 , pp. 169-178
    • Berry, E.B.1    Keelan, J.A.2    Helliwell, R.J.3    Gilmour, R.S.4    Mitchell, M.D.5
  • 64
    • 0023724778 scopus 로고
    • I kappa B. A specific inhibitor of the NF-kappa B transcription factor
    • P.A. Baeuerle, and D. Baltimore I kappa B. A specific inhibitor of the NF-kappa B transcription factor Science 242 1988 540 546
    • (1988) Science , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 65
    • 0035504081 scopus 로고    scopus 로고
    • Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer
    • S.D. Catz, and J.L. Johnson Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer Oncogene 20 2001 7342 7351
    • (2001) Oncogene , vol.20 , pp. 7342-7351
    • Catz, S.D.1    Johnson, J.L.2
  • 68
    • 84887241795 scopus 로고    scopus 로고
    • Insights into significant pathways and gene interaction networks underlying breast cancer cell line MCF-7 treated with 17β-estradiol (E2)
    • J. Huan, L. Wang, L. Xing, X. Qin, L. Feng, X. Pan, and L. Zhu Insights into significant pathways and gene interaction networks underlying breast cancer cell line MCF-7 treated with 17β-estradiol (E2) Gene 533 2014 346 355
    • (2014) Gene , vol.533 , pp. 346-355
    • Huan, J.1    Wang, L.2    Xing, L.3    Qin, X.4    Feng, L.5    Pan, X.6    Zhu, L.7
  • 70
    • 1442285889 scopus 로고    scopus 로고
    • Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
    • E.M. Hurt, A. Wiestner, A. Rosenwald, A. Shaffer, E. Campo, T. Grogan, P.L. Bergsagel, W.M. Kuehl, and L.M. Staudt Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma Cancer Cell 5 2004 191 199
    • (2004) Cancer Cell , vol.5 , pp. 191-199
    • Hurt, E.M.1    Wiestner, A.2    Rosenwald, A.3    Shaffer, A.4    Campo, E.5    Grogan, T.6    Bergsagel, P.L.7    Kuehl, W.M.8    Staudt, L.M.9
  • 71
    • 53849101060 scopus 로고    scopus 로고
    • C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma
    • S. Mahner, C. Baasch, J. Schwarz, S. Hein, L. Wölber, F. Jänicke, and K. Milde-Langosch C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma Br. J. Cancer 99 2008 1269 1275
    • (2008) Br. J. Cancer , vol.99 , pp. 1269-1275
    • Mahner, S.1    Baasch, C.2    Schwarz, J.3    Hein, S.4    Wölber, L.5    Jänicke, F.6    Milde-Langosch, K.7
  • 78
    • 0037251255 scopus 로고    scopus 로고
    • WISP-2 gene in human breast cancer: Estrogen and progesterone inducible expression and regulation of tumor cell proliferation
    • S. Banerjee, N. Saxena, K. Sengupta, O. Tawfik, M.S. Mayo, and S.K. Banerjee WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation Neoplasia 5 2003 63 73
    • (2003) Neoplasia , vol.5 , pp. 63-73
    • Banerjee, S.1    Saxena, N.2    Sengupta, K.3    Tawfik, O.4    Mayo, M.S.5    Banerjee, S.K.6
  • 80
    • 0034213320 scopus 로고    scopus 로고
    • Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models
    • H. Miyake, M. Pollak, and M.E. Gleave Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models Cancer Res. 60 2000 3058 3064
    • (2000) Cancer Res. , vol.60 , pp. 3058-3064
    • Miyake, H.1    Pollak, M.2    Gleave, M.E.3
  • 85
    • 84872002796 scopus 로고    scopus 로고
    • SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ERα transcriptional activity
    • L. Zhang, C. Gong, S.L. Lau, N. Yang, O.G. Wong, A.N. Cheung, J.W. Tsang, K.Y. Chan, and U.-S. Khoo SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ERα transcriptional activity Cancer Res. 73 2013 246 255
    • (2013) Cancer Res. , vol.73 , pp. 246-255
    • Zhang, L.1    Gong, C.2    Lau, S.L.3    Yang, N.4    Wong, O.G.5    Cheung, A.N.6    Tsang, J.W.7    Chan, K.Y.8    Khoo, U.-S.9
  • 86
    • 84907062674 scopus 로고    scopus 로고
    • The SMRT coregulator enhances growth of estrogen receptor-α-Positive Breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis
    • J.K. Blackmore, S. Karmakar, G. Gu, V. Chaubal, L. Wang, W. Li, and C.L. Smith The SMRT coregulator enhances growth of estrogen receptor-α-Positive Breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis Endocrinology 155 2014 3251 3261
    • (2014) Endocrinology , vol.155 , pp. 3251-3261
    • Blackmore, J.K.1    Karmakar, S.2    Gu, G.3    Chaubal, V.4    Wang, L.5    Li, W.6    Smith, C.L.7
  • 87
    • 79960228013 scopus 로고    scopus 로고
    • CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
    • S. Braig, S. Wallner, B. Junglas, R. Fuchshofer, and A. Bosserhoff CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration Br. J. Cancer 105 2011 231 238
    • (2011) Br. J. Cancer , vol.105 , pp. 231-238
    • Braig, S.1    Wallner, S.2    Junglas, B.3    Fuchshofer, R.4    Bosserhoff, A.5
  • 88
    • 84878635691 scopus 로고    scopus 로고
    • Reduced CTGF expression promotes cell growth migration and invasion in nasopharyngeal carcinoma
    • Y. Zhen, Y. Ye, X. Yu, C. Mai, Y. Zhou, Y. Chen, H. Yang, X. Lyu, Y. Song, and Q. Wu Reduced CTGF expression promotes cell growth migration and invasion in nasopharyngeal carcinoma PLoS One 8 6 2013 e64976
    • (2013) PLoS One , vol.8 , Issue.6
    • Zhen, Y.1    Ye, Y.2    Yu, X.3    Mai, C.4    Zhou, Y.5    Chen, Y.6    Yang, H.7    Lyu, X.8    Song, Y.9    Wu, Q.10


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