The Sertoli cell: One hundred fifty years of beauty and plasticity

Andrology

Volumn 4, Issue 2, 2016, Pages 189-212

  Franca L R ^a,b   Hess, R A ^c   Dufour, J M ^d   Hofmann, M C ^e   Griswold, M D ^f  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA   (Brazil)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Amniotes; Anamniotes; Blood testis barrier; Germ cell; Immune privilege; Immune tolerance; Sertoli cell; Spermatogenesis; Stem cell niche; Testis

Indexed keywords

ANIMAL CELL; ARTICLE; BLOOD TESTIS BARRIER; CELL HOMING; CELL MIGRATION; CELL NUCLEUS; CELL PLASTICITY; CELL SELF-RENEWAL; CELL STRUCTURE; CYTOPLASM; ELECTRON MICROSCOPY; GERM CELL; IMMUNOREGULATION; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; SERTOLI CELL; ANDROLOGY; ANIMAL; ART; HISTORY; HUMAN; MALE;

ANDROLOGY; ANIMALS; HISTORY, 19TH CENTURY; HUMANS; MALE; SERTOLI CELLS;

EID: 84959535117     PISSN: 20472919     EISSN: 20472927     Source Type: Journal    
DOI: 10.1111/andr.12165     Document Type: Article

References (455)

1. Aflatoonian B, Ruban L, Jones M, Aflatoonian R, Fazeli A & Moore HD. (2009) In vitro post-meiotic germ cell development from human embryonic stem cells. Hum Reprod 24, 3150-3159.
2. Almeida FF, Kristoffersen C, Taranger GL & Schulz RW. (2008) Spermatogenesis in Atlantic cod (Gadus morhua): a novel model of cystic germ cell development. Biol Reprod 78, 27-34.
3. Andersson A-M (2001) Inhibin B as a serum marker of spermatogenesis. In: Andrology in the 21st Century (eds B Robaire, H Chemes & CR Morales ), pp. 123-130. Medimond Publishing Company, New Jersey.
4. Aponte PM, Soda T, Teerds KJ, Mizrak SC, van de Kant HJ & de Rooij DG. (2008) Propagation of bovine spermatogonial stem cells in vitro. Reproduction 136, 543-557.
5. Ara T, Nakamura Y, Egawa T, Sugiyama T, Abe K, Kishimoto T, Matsui Y & Nagasawa T. (2003) Impaired colonization of the gonads by primordial germ cells in mice lacking a chemokine, stromal cell-derived factor-1 (SDF-1). Proc Natl Acad Sci USA 100, 5319-5323.
6. Armstrong DT, Moon YS, Fritz IB & Dorrington JH. (1975) Synthesis of estradiol-17 beta by Sertoli cells in culture: stimulation by FSH and dibutyryl cyclic AMP. Curr Top Mol Endocrinol 2, 85-96.
7. Assis LH, Crespo D, Morais RD, Franca LR, Bogerd J & Schulz RW. (2015) INSL3 stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio). Cell Tissue Res, PMID: 26077926 (In Press).
8. Baraniak PR & McDevitt TC. (2010) Stem cell paracrine actions and tissue regeneration. Regen Med 5, 121-143.
9. Bardin CW, Cheng CY, Musto NA & Gunsalus GL (1988) The Sertoli cell. In: The Physiology of Reproduction (eds E Knobil & J Neill ), pp. 933-974. Raven Press, Ltd., New York.
10. Barker CF & Billingham RE. (1977) Immunologically privileged sites. Adv Immunol 25, 1-54.
11. Barrionuevo F, Burgos M & Jimenez R. (2011) Origin and function of embryonic Sertoli cells. Biomolecular Concepts 2, 537-547.
12. Bartke A, Sinha Hikim AP & Russell LD (1993) Sertoli cell structure and function in seasonally breeding mammals. In: The Sertoli Cell (eds M D Griswold & L D Russell ), pp. 349-364. Cache River Press, Clearwater, FL.
13. Beach SF & Vogl AW. (1999) Spermatid translocation in the rat seminiferous epithelium: coupling membrane trafficking machinery to a junction plaque. Biol Reprod 60, 1036-1046.
14. Berruti G & Paiardi C. (2014) The dynamic of the apical ectoplasmic specialization between spermatids and Sertoli cells: the case of the small GTPase Rap1. Biomed Res Int 2014, 635979.
15. Beverdam A & Koopman P. (2006) Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes. Hum Mol Genet 15, 417-431.
16. Billard R & Breton B (1978) Rhythm of reproduction in teleost fish. In: Rhythmic Activity of Fishes (ed J E Thorpe ), pp. 31-53. Academic Press, New York.
17. Boekelheide K (1993) Sertoli cell toxicants. In: The Sertoli Cell (eds LD Russell & MD Griswold ), pp. 551-576. Cache River Press, Clearwater, FL.
18. Boekelheide K, Neely MD & Sioussat TM. (1989) The Sertoli cell cytoskeleton: a target for toxicant-induced germ cell loss. Toxicol Appl Pharmacol 101, 373-389.
19. Brehm R & Steger K. (2005) Regulation of Sertoli cell and germ cell differentation. Adv Anat Embryol Cell Biol 181, 1-93.
20. Brökelmann J. (1963) Fine structure of germ cells and Sertoli cells during the cycle of the seminiferous epithelium in the rat. Z Zellforsch Mikrosk Anat 59, 820-850.
21. Brunocilla E, Pultrone CV, Schiavina R, Rocca C, Passaretti G, Corti B & Martorana G. (2012) Testicular sclerosing Sertoli cell tumor: an additional case and review of the literature. Anticancer Res 32, 5127-5130.
22. Burger HG & de Kretser D (1981) (eds) The Testis. Raven Press, New York, 442p.
23. Burgos MH & Fawcett DW. (1955) Studies on the fine structure of the mammalian testis. I. Differentiation of the spermatids in the cat (Felis domestica). J Biophys Biochem Cytol 1, 287-300.
24. Bustos-Obregon E. (1970) On Sertoli cell number and distribution in rat testis. Arch Biol (Liege) 81, 99-108.
25. Byers S, Jegou B, MacCalman C & Blaschuk O (1993a) Sertoli cell adhesion molecules and the collective organization of the testis. In: The Sertoli Cell (eds M D Griswold & L D Russell ), pp. 461-476. Cache River Press, Clearwater, FL.
26. Byers S, Pelletier R-M & Suarez-Quian C (1993b) Sertoli-Sertoli cell junctions and the seminiferous epithelium barrier. In: The Sertoli Cell (eds M D Griswold & L D Russell ), pp. 431-446. Cache River Press, Clearwater, FL.
27. Caires KC, de Avila J & McLean DJ. (2012a) Endocrine regulation of spermatogonial stem cells in the seminiferous epithelium of adult mice. Biores Open Access 1, 222-230.
28. Caires KC, de Avila JM, Cupp AS & McLean DJ. (2012b) VEGFA family isoforms regulate spermatogonial stem cell homeostasis in vivo. Endocrinology 153, 887-900.
29. Campbell B, Dickey JT & Swanson P. (2003) Endocrine changes during onset of puberty in male spring Chinook salmon, Oncorhynchus tshawytscha. Biol Reprod 69, 2109-2117.
30. Cavicchia JC & Dym M. (1977) Relative volume of Sertoli cells in monkey seminiferous epithelium: a stereological analysis. Am J Anat 150, 501-507.
31. Cavicchia JC, Sacerdote FL, Morales A & Zhu BC. (1998) Sertoli cell nuclear pore number changes in some stages of the spermatogenic cycle of the rat seminiferous epithelium. Tissue Cell 30, 268-273.
32. Chakraborty P, William Buaas F, Sharma M, Smith BE, Greenlee AR, Eacker SM & Braun RE. (2014) Androgen-dependent sertoli cell tight junction remodeling is mediated by multiple tight junction components. Mol Endocrinol 28, 1055-1072.
33. Chen C, Ouyang W, Grigura V, Zhou Q, Carnes K, Lim H, Zhao GQ, Arber S, Kurpios N, Murphy TL, Cheng AM, Hassell JA, Chandrashekar V, Hofmann MC, Hess RA & Murphy KM. (2005) ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature 436, 1030-1034.
34. Chen SX, Bogerd J, Schoonen NE, Martijn J, de Waal PP & Schulz RW. (2013) A progestin (17alpha, 20beta-dihydroxy-4-pregnen-3-one) stimulates early stages of spermatogenesis in zebrafish. Gen Comp Endocrinol 185, 1-9.
35. Cheng CY, Grima J, Lee WM & Bardin CW. (1987) The distribution of rat testibumin in the male reproductive tract. Biol Reprod 37, 875-885.
36. Cheng CY, Grima J, Stahler MS, Guglielmotti A, Silvestrini B & Bardin CW. (1990) Sertoli cell synthesizes and secretes a protease inhibitor, alpha 2-macroglobulin. Biochemistry 29, 1063-1068.
37. Cheng CY & Mruk DD. (2002) Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development. Physiol Rev 82, 825-874.
38. Cheng CY & Mruk DD. (2009) An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective. Crit Rev Biochem Mol Biol 44, 245-263.
39. Cheng CY & Mruk DD. (2010) A local autocrine axis in the testes that regulates spermatogenesis. Nat Rev Endocrinol 6, 380-395.
40. Cheng CY & Mruk DD. (2012) The blood-testis barrier and its implications for male contraception. Pharmacol Rev 64, 16-64.
41. Cheng CY & Mruk DD (2015) Biochemistry of Sertoli cell/germ cell junctions, germ cell transport, and spermiation in the seminiferous epithelium. In: Sertoli Cell Biology (ed M Griswold ), pp. 333-383. Elsevier Academic Press, Oxford.
42. Cheng CY, Wong EW, Lie PP, Li MW, Mruk DD, Yan HH, Mok KW, Mannu J, Mathur PP, Lui WY, Lee WM, Bonanomi M & Silvestrini B. (2011) Regulation of blood-testis barrier dynamics by desmosome, gap junction, hemidesmosome and polarity proteins: an unexpected turn of events. Spermatogenesis 1, 105-115.
43. Cheng CY, Wong EW, Yan HH & Mruk DD. (2010) Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: new insights and advances. Mol Cell Endocrinol 315, 49-56.
44. Chiarini-Garcia H, Hornick JR, Griswold MD & Russell LD. (2001) Distribution of type A spermatogonia in the mouse is not random. Biol Reprod 65, 1179-1185.
45. Chiarini-Garcia H, Raymer AM & Russell LD. (2003) Non-random distribution of spermatogonia in rats: evidence of niches in the seminiferous tubules. Reproduction 126, 669-680.
46. Chihara M, Ikebuchi R, Otsuka S, Ichii O, Hashimoto Y, Suzuki A, Saga Y & Kon Y. (2013) Mice stage-specific claudin 3 expression regulates progression of meiosis in early stage spermatocytes. Biol Reprod 89, 3.
47. Chojnacka K & Mruk DD. (2015) The Src non-receptor tyrosine kinase paradigm: new insights into mammalian Sertoli cell biology. Mol Cell Endocrinol 415, 133-142.
48. Chowdhury M, Steinberger A & Steinberger E. (1978) Inhibition of de novo synthesis of FSH by the Sertoli cell factor (SCF). Endocrinology 103, 644-647.
49. Clermont Y (1993) Introduction to the Sertoli cell. In: The Sertoli Cell (eds L D Russell & M D Griswold ), pp. xxi-xxv. Cache River Press, Clearwater, FL.
50. Clermont Y, Morales C & Hermo L. (1987) Endocytic activities of Sertoli cells in the rat. Ann N Y Acad Sci 513, 1-15.
51. Clermont Y & Morgentaler H. (1955) Quantitative study of spermatogenesis in the hypophysectomized rat. Endocrinology 57, 369-382.
52. Clevers H, Loh KM & Nusse R. (2014) Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science 346, 1248012.
53. Cooke PS, Holsberger DR & França LR (2005) Thyroid hormone regulation of Sertoli cell development. In: Sertoli Cell Biology (eds M K Skinner & M D Griswold ), pp. 217-226. Elsevier Academic Press, San Diego.
54. De Gendt K, Verhoeven G, Amieux PS & Wilkinson MF. (2014) Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach. Mol Endocrinol 28, 575-591.
55. de Kretser DM. (1990) Germ cell-Sertoli cell interactions. Reprod Fertil Dev 2, 225-235.
56. de Kretser DM, Loveland KL, Meehan T, O'Bryan MK, Phillips DJ & Wreford NG. (2001) Inhibins, activins and follistatin: actions on the testis. Mol Cell Endocrinol 180, 87-92.
57. de Rooij DG (2015) The spermatogonial stem cell niche in mammals. In: Sertoli Cell Biology (ed M Griswold ), pp. 99-122. Elsevier Academic Press, Oxford.
58. de Winter JP, Vanderstichele HM, Timmerman MA, Blok LJ, Themmen AP & de Jong FH (1993) Activin is produced by rat Sertoli cells in vitro and can act as an autocrine regulator of Sertoli cell function. Endocrinology 132, 975-982.
59. Demoulin A, Koulischer L, Hustin J, Hazee-Hagelstein MT, Lambotte R & Franchimont P (1979) Organ culture of mammalian testis. III. Inhibin secretion. Horm Res 10, 177-190.
60. DiNapoli L & Capel B (2008) SRY and the standoff in sex determination. Mol Endocrinol 22, 1-9.
61. Djakiew D & Onoda M (1993) Multichamber cell culture and directional secretion. In: The Sertoli Cell (eds L D Russell & M D Griswold ), pp. 181-194. Cache River Press, Clearwater, FL.
62. Doitsidou M, Reichman-Fried M, Stebler J, Koprunner M, Dorries J, Meyer D, Esguerra CV, Leung T & Raz E. (2002) Guidance of primordial germ cell migration by the chemokine SDF-1. Cell 111, 647-659.
63. Dong WL, Tan FQ & Yang WX. (2015) Wnt signaling in testis development: unnecessary or essential? Gene 565, 155-165.
64. Dorrington JH & Armstrong DT. (1975) Follicle-stimulating hormone stimulates estradiol-17beta synthesis in cultured Sertoli cells. Proc Natl Acad Sci USA 72, 2677-2681.
65. Dorrington JH & Khan SA (1993) Steroid production, metabolism, and release by Sertoli cells. In: The Sertoli Cell (eds M D Griswold & L D Russell ), pp. 537-550. Cache River Press, Clearwater, FL.
66. Dovere L, Fera S, Grasso M, Lamberti D, Gargioli C, Muciaccia B, Lustri AM, Stefanini M & Vicini E. (2013) The niche-derived glial cell line-derived neurotrophic factor (GDNF) Induces migration of mouse spermatogonial stem/progenitor cells. PLoS ONE 8, e59431.
67. Doyle TJ, Kaur G, Putrevu SM, Dyson EL, Dyson M, McCunniff WT, Pasham MR, Kim KH & Dufour JM. (2012) Immunoprotective properties of primary Sertoli cells in mice: potential functional pathways that confer immune privilege. Biol Reprod 86, 1-14.
68. Du M, Young J, De Asis M, Cipollone J, Roskelley C, Takai Y, Nicholls PK, Stanton PG, Deng W, Finlay BB & Vogl AW. (2013) A novel subcellular machine contributes to basal junction remodeling in the seminiferous epithelium. Biol Reprod 88, 60.
69. Dufour JM, Hamilton M, Rajotte RV & Korbutt GS. (2005) Neonatal porcine Sertoli cells inhibit human natural antibody-mediated lysis. Biol Reprod 72, 1224-1231.
70. Dufour JM, Hemendinger R, Halberstadt CR, Gores P, Emerich DF, Korbutt GS & Rajotte RV. (2004) Genetically engineered Sertoli cells are able to survive allogeneic transplantation. Gene Ther 11, 694-700.
71. Dufour JM, Rajotte RV, Korbutt GS & Emerich DF. (2003a) Harnessing the immunomodulatory properties of Sertoli cells to enable xenotransplantation in type I diabetes. Immunol Invest 32, 275-297.
72. Dufour JM, Rajotte RV, Seeberger K, Kin T & Korbutt GS. (2003b) Long-term survival of neonatal porcine Sertoli cells in non-immunosuppressed rats. Xenotransplantation 10, 577-586.
73. Dym M. (1973) The fine structure of the monkey (Macaca) Sertoli cell and its role in maintaining the blood-testis barrier. Anat Rec 175, 639-656.
74. Dym M. (1994) Basement membrane regulation of Sertoli cells. Endocr Rev 15, 102-115.
75. Dym M & Fawcett DW. (1970) The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol Reprod 3, 308-326.
76. Dym M & Romrell LJ. (1975) Intraepithelial lymphocytes in the male reproductive tract of rats and rhesus monkeys. J Reprod Fertil 42, 1-7.
77. Ebner V. (1888) Zur Spermatogenese bei den Säugethieren. Arch Mikr Anat 31, 236-291.
78. El-Darwish KS, Parvinen M & Toppari J. (2006) Differential expression of members of the E2F family of transcription factors in rodent testes. Reprod Biol Endocrinol 4, 63.
79. Elftman H. (1950) The Sertoli cell cycle in the mouse. Anat Rec 106, 381-392.
80. Elftman H. (1963) Sertoli cells and testis structure. Am J Anat 113, 25-33.
81. Escott GM, da Rosa LA & Loss Eda S. (2014) Mechanisms of hormonal regulation of sertoli cell development and proliferation: a key process for spermatogenesis. Curr Mol Pharmacol 7, 96-108.
82. Evans E, Hogarth C, Mitchell D & Griswold M (2014) Riding the spermatogenic wave: profiling gene expression within neonatal germ and sertoli cells during a synchronized initial wave of spermatogenesis in mice. Biol Reprod 90, 108.
83. Ewing LL & Robaire B (1989) (eds) Regulation of Testicular Function: Signaling Molecules and Cell-Cell Communication. p. 305. The New York Academy of Science, New York.
84. Fawcett DW (1975) Ultrastructure and function of the Sertoli cell. In: Handbook of Physiology, vol. 5 (eds D W Hamilton & R O Greep ), pp. 21-55. American Physiology Society, Washington, DC.
85. Fawcett DW & Burgos M. (1956) The fine structure of the Sertoli cells in the human testis. Anat Rec 124, 401-402.
86. Fawcett DW, Leak LV & Heidger PM Jr. (1970) Electron microscopic observations on the structural components of the blood-testis barrier. J Reprod Fertil Suppl 10, 105-122.
87. Fawcett DW & Phillips DM. (1969) Observations on the release of spermatozoa and on changes in the head during passage through the epididymis. J Reprod Fert Suppl 6, 405-418.
88. Flickinger C & Fawcett DW. (1967) The junctional specializations of Sertoli cells in the seminiferous epithelium. Anat Rec 158, 207-221.
89. Fok KL, Chen H, Ruan YC & Chan HC. (2014) Novel regulators of spermatogenesis. Semin Cell Dev Biol 29, 31-42.
90. Franca LR, Auharek SA, Hess RA, Dufour JM & Hinton BT. (2012) Blood-tissue barriers: morphofunctional and immunological aspects of the blood-testis and blood-epididymal barriers. Adv Exp Med Biol 763, 237-259.
91. França LR, Nóbrega RH, Morais RDVS, Assis LHC & Schulz RW. (2015) Sertoli cell structure and function in anamniote vertebrates. In: Sertoli Cell Biology(ed. M Griswold ), pp. 385-407. Elsevier Academic Press, San Diego.
92. Fritz IB. (1982) Comparison of granulosa and sertoli cells at various stages of maturation: similarities and differences. Adv Exp Med Biol 147, 357-384.
93. Fritz IB, Griswold MD, Louis BG & Dorrington JH. (1976) Similarity of responses of cultured Sertoli cells to cholera toxin and FSH. Mol Cell Endocrinol 5, 289-294.
94. Fritz IB, Tung PS & Ailenberg M. (1993) Proteases and antiproteases in the seminiferous tubule. In: The Sertoli Cell(eds. MD Griswold & LD Russell ), pp. 217-236. Cache River Press, Clearwater, FL.
95. Frojdman K, Harley VR & Pelliniemi LJ. (2000) Sox9 protein in rat sertoli cells is age and stage dependent. Histochem Cell Biol 113, 31-36.
96. Gao F, Maiti S, Alam N, Zhang Z, Deng JM, Behringer RR, Lecureuil C, Guillou F & Huff V. (2006) The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci USA 103, 11987-11992.
97. Gao Y, Mruk DD & Cheng CY. (2015) Sertoli cells are the target of environmental toxicants in the testis - a mechanistic and therapeutic insight. Expert Opin Ther Targets 19, 1073-1090.
98. Garcia TX, DeFalco T, Capel B & Hofmann MC. (2013) Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. Dev Biol 377, 188-201.
99. Garcia TX, Farmaha JK, Kow S & Hofmann MC. (2014) RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development 141, 4468-4478.
100. Garcia TX & Hofmann MC. (2013) NOTCH signaling in Sertoli cells regulates gonocyte fate. Cell Cycle 12, 2538-2545.
101. Gassei K & Schlatt S. (2007) Testicular morphogenesis: comparison of in vivo and in vitro models to study male gonadal development. Ann N Y Acad Sci 1120, 152-167.
102. Golestaneh N, Beauchamp E, Fallen S, Kokkinaki M, Uren A & Dym M. (2009) Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells. Reproduction 138, 151-162.
103. Gondos B & Berndston WE. (1993) Postnatal and pubertal development. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 115-154. Cache River Press, Clearwater, FL.
104. Gow A, Southwood CM, Li JS, Pariali M, Riordan GP, Brodie SE, Danias J, Bronstein JM, Kachar B & Lazzarini RA. (1999) CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice. Cell 99, 649-659.
105. Grasso M, Fuso A, Dovere L, de Rooij DG, Stefanini M, Boitani C & Vicini E. (2012) Distribution of GFRA1-expressing spermatogonia in adult mouse testis. Reproduction 143, 325-332.
106. Grier HJ. (1993) Comparative organization of Sertoli cells including the Sertoli cell barrier. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 703-740. Cache River Press, Clearwater, FL.
107. Griswold MD. (1988) Protein secretions of Sertoli cells. Int Rev Cytol 110, 133-156.
108. Griswold MD. (1993a) Action of FSH on mammalian Sertoli cells. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 493-508. Cache River Press, Clearwater, FL.
109. Griswold MD. (1993b) Protein secretion by Sertoli cells: general considerations. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 195-200. Cache River Press, Clearwater, FL.
110. Griswold MD. (1993c) Unique aspects of the biochemistry and metabolism of Sertoli cells. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 485-492. Cache River Press, Clearwater, FL.
111. Griswold MD. (1995) Interactions between germ cells and Sertoli cells in the testis. Biol Reprod 52, 211-216.
112. Griswold MD. (1998) The central role of Sertoli cells in spermatogenesis. Semin Cell Dev Biol 9, 411-416.
113. Griswold MD. (2015a) The initiation of spermatogenesis and the cycle of the seminiferous epithelium. In: Sertoli Cell Biology(ed. MD Griswold ), pp. 233-245. Elsevier Academic Press, Oxford.
114. Griswold MD (2015b) (ed) Sertoli Cell Biology. Elsevier Academic Press, Oxford, 469p.
115. Griswold MD. (2016) Spermatogenesis: the commitment to meiosis. Physiol Rev 96, 1-17.
116. Griswold MD & McLean D. (2005) Sertoli cell gene expression and protein secretion. In: Sertoli Cell Biology (eds. M Skinner & M Griswold ), pp. 95-106. Academic Press, San Diego.
117. Griswold MD, Morales C & Sylvester SR. (1988) Molecular biology of the Sertoli cell. Oxf Rev Reprod Biol 10, 124-161.
118. Guazzone VA, Jacobo P, Theas MS & Lustig L. (2009) Cytokines and chemokines in testicular inflammation: a brief review. Microsc Res Tech 72, 620-628.
119. Gungor-Ordueri NE, Celik-Ozenci C & Cheng CY (2014) Fascin 1 is an actin filament bundling protein that regulates ectoplasmic specialization dynamics in the rat testis. Am J Physiol Endocrinol Metab 307, E738-753.
120. Guraya SS. (1995) The comparative cell biology of accessory somatic (or Sertoli) cells in the animal testis. Int Rev Cytol 160, 163-220.
121. Guttenbach M, Martinez-Exposito MJ, Engel W & Schmid M. (1996) Interphase chromosome arrangement in Sertoli cells of adult mice. Biol Reprod 54, 980-986.
122. Hai Y, Hou J, Liu Y, Liu Y, Yang H, Li Z & He Z. (2014) The roles and regulation of Sertoli cells in fate determinations of spermatogonial stem cells and spermatogenesis. Semin Cell Dev Biol 29, 66-75.
123. Halley K, Dyson EL, Kaur G, Mital P, Uong PM, Dass B, Crowell SN & Dufour JM. (2010) Delivery of a therapeutic protein by immune-privileged Sertoli cells. Cell Transplant 19, 1645-1657.
124. Heckert L & Griswold MD. (1993) Expression of the FSH receptor in the testis. Recent Prog Horm Res 48, 61-77.
125. Heckert LL & Agbor VA. (2015) DMRT1 and the road to masculinity. In: Sertoli Cell Biology(ed. M Griswold ), pp. 123-174. Elsevier Academic Press, Oxford.
126. Hedger MP (2015) The Immunophysiology of Male Reproduction. Academic Press, New York, pp. 805-889.
127. Heller CG, Maddock WO, et al. (1948) The Sertoli cell. J Clin Invest 27, 540.
128. Hermo L, Pelletier RM, Cyr DG & Smith CE. (2010) Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 5: intercellular junctions and contacts between germs cells and Sertoli cells and their regulatory interactions, testicular cholesterol, and genes/proteins associated with more than one germ cell generation. Microsc Res Tech 73, 409-494.
129. Hess R & França LR. (2005) Structure of the Sertoli cell. In: Sertoli Cell Biology (eds. M Griswold & M Skinner ), pp. 19-40. Elsevier Academic Press, San Diego.
130. Hess RA. (1990) Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: light microscopic observations of perfusion-fixed and plastic-embedded testes. Biol Reprod 43, 525-542.
131. Hess RA, Cooke PS, Bunick D & Kirby JD. (1993) Adult testicular enlargement induced by neonatal hypothyroidism is accompanied by increased Sertoli and germ cell numbers. Endocrinology 132, 2607-2613.
132. Hess RA & Vogl AW. (2015) Sertoli cell anatomy and cytoskeleton. In: Sertoli Cell Biology(ed. M Griswold ), pp. 1-55. Elsevier Academic Press, Oxford.
133. Higuchi M, Celino FT, Tamai A, Miura C & Miura T. (2012) The synthesis and role of taurine in the Japanese eel testis. Amino Acids 43, 773-781.
134. Higuchi M, Miura C, Iwai T & Miura T. (2013) Trypsin regulates meiotic initiation in the Japanese eel (Anguilla japonica) by promoting the uptake of taurine into germ cells during spermatogenesis. Biol Reprod 89, 58.
135. Hinsch GW. (1993) Comparative organization and cytology of Sertoli cells in invertebrates. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 659-684. Cache River Press, Clearwater, FL.
136. Hinton BT & Setchell BP. (1993) Fluid secretion and movement. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 249-267. Cache River Press, Clearwater, FL.
137. Hogarth C. (2015) Retinoic acid metabolism, signaling, and function in the adult testis. In: Sertoli Cell Biology(ed. M Griswold ), pp. 247-272. Elsevier Academic Press, Oxford.
138. Hogarth CA & Griswold MD. (2010) The key role of vitamin A in spermatogenesis. J Clin Invest 120, 956-962.
139. Hogarth CA & Griswold MD. (2013) Immunohistochemical approaches for the study of spermatogenesis. Methods Mol Biol 927, 309-320.
140. Innes JRM. (1942) Neoplastic diseases of the testis in animals. J Path Bact 54, 485-498.
141. Ishii K, Kanatsu-Shinohara M, Toyokuni S & Shinohara T. (2012) FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation. Development 139, 1734-1743.
142. Jacobo P, Guazzone VA, Theas MS & Lustig L. (2011) Testicular autoimmunity. Autoimmun Rev 10, 201-204.
143. Jakob S & Lovell-Badge R. (2011) Sex determination and the control of Sox9 expression in mammals. FEBS J 278, 1002-1009.
144. Jean P, Hartung M, Mirre C & Stahl A. (1983) Association of centromeric heterochromatin with the nucleolus in mouse Sertoli cells. Anat Rec 205, 375-380.
145. Jegou B. (1991) Spermatids are regulators of Sertoli cell function. Ann N Y Acad Sci 637, 340-353.
146. Jegou B. (1992a) The Sertoli cell. Baillieres Clin Endocrinol Metab 6, 273-311.
147. Jegou B. (1992b) The Sertoli cell in vivo and in vitro. Cell Biol Toxicol 8, 49-54.
148. Jegou B. (1993) The Sertoli-germ cell communication network in mammals. Int Rev Cytol 147, 25-96.
149. Jegou B, Stephan JP, Cudicini C, Gomez E, Bauche F, Piquet-Pellorce C & Touzalin AM. (2000) The Sertoli cell-germ cell interactions and the seminiferous tubule interleukin-1 and interleukin-6 system. Results Probl Cell Differ 28, 53-68.
150. Jiang XH, Bukhari I, Zheng W, Yin S, Wang Z, Cooke HJ & Shi QH (2014) Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice. Asian J Androl 16, 572-580.
151. Johnson KJ (2014) Testicular histopathology associated with disruption of the Sertoli cell cytoskeleton. Spermatogenesis 4, e979106.
152. Johnson L & Thompson DL Jr (1983) Age-related and seasonal variation in the Sertoli cell population, daily sperm production and serum concentrations of follicle-stimulating hormone, luteinizing hormone and testosterone in stallions. Biol Reprod 29, 777-789.
153. Johnson L, Thompson DL Jr & Varner DD. (2008) Role of Sertoli cell number and function on regulation of spermatogenesis. Anim Reprod Sci 105, 23-51.
154. Johnson L, Zane RS, Petty CS & Neaves WB. (1984) Quantification of the human Sertoli cell population: its distribution, relation to germ cell numbers, and age-related decline. Biol Reprod 31, 785-795.
155. Johnson MH. (1972) The distribution of immunoglobulin and spermatozoal autoantigen in the genital tract of the male guinea pig: its relationship to autoallergic orchitis. Fertil Steril 23, 383-392.
156. Johnson MH & Setchell BP. (1968) Protein and immunoglobulin content of rete testis fluid of rams. J Reprod Fertil 17, 403-406.
157. Johnston DS, Olivas E, DiCandeloro P & Wright WW. (2011) Stage-specific changes in GDNF expression by rat Sertoli cells: a possible regulator of the replication and differentiation of stem spermatogonia. Biol Reprod 85, 763-769.
158. Johnston DS, Russell LD, Friel PJ & Griswold MD. (2001) Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation. Endocrinology 142, 2405-2408.
159. Johnston DS, Wright WW, Dicandeloro P, Wilson E, Kopf GS & Jelinsky SA. (2008) Stage-specific gene expression is a fundamental characteristic of rat spermatogenic cells and Sertoli cells. Proc Natl Acad Sci USA 105, 8315-8320.
160. Josso N. (1992) Anti-mullerian hormone and Sertoli cell function. Horm Res 38(Suppl 2), 72-76.
161. Kaipia A, Parvinen M, Shimasaki S, Ling N & Toppari J. (1991) Stage-specific cellular regulation of inhibin alpha-subunit mRNA expression in the rat seminiferous epithelium. Mol Cell Endocrinol 82, 165-173.
162. Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Yoshida S, Toyokuni S, Lee J, Ogura A & Shinohara T. (2007) Leukemia inhibitory factor enhances formation of germ cell colonies in neonatal mouse testis culture. Biol Reprod 76, 55-62.
163. Kanatsu-Shinohara M, Inoue K, Takashima S, Takehashi M, Ogonuki N, Morimoto H, Nagasawa T, Ogura A & Shinohara T. (2012) Reconstitution of mouse spermatogonial stem cell niches in culture. Cell Stem Cell 11, 567-578.
164. Kanatsu-Shinohara M, Ogonuki N, Inoue K, Miki H, Ogura A, Toyokuni S & Shinohara T. (2003) Long-term proliferation in culture and germline transmission of mouse male germline stem cells. Biol Reprod 69, 612-616.
165. Kaur G, Long CR & Dufour JM. (2012) Genetically engineered immune privileged Sertoli cells: a new road to cell based gene therapy. Spermatogenesis 2, 23-31.
166. Kaur G, Mital P & Dufour JM. (2013) Testisimmune privilege - assumptions facts. Anim Reprod 10, 3-15.
167. Kaur G, Thompson LA & Dufour JM. (2015) Therapeutic potential of immune privileged Sertoli cells. Anim Reprod 12, 105-117.
168. Kaur G, Thompson LA & Dufour JM. (2014a) Sertoli cells - immunological sentinels of spermatogenesis. Semin Cell Dev Biol 30, 36-44.
169. Kaur G, Thompson LA, Pasham M, Tessanne K, Long CR & Dufour JM. (2014b) Sustained expression of insulin by a genetically engineered Sertoli cell line after allotransplantation in diabetic BALB/c mice. Biol Reprod 90, 109.
170. Kent J, Wheatley SC, Andrews JE, Sinclair AH & Koopman P. (1996) A male-specific role for SOX9 in vertebrate sex determination. Development 122, 2813-2822.
171. Kerkis A, Fonseca SA, Serafim RC, Lavagnolli TM, Abdelmassih S, Abdelmassih R & Kerkis I. (2007) In vitro differentiation of male mouse embryonic stem cells into both presumptive sperm cells and oocytes. Cloning Stem Cells 9, 535-548.
172. Kerr GE, Young JC, Horvay K, Abud HE & Loveland KL. (2014) Regulated Wnt/beta-catenin signaling sustains adult spermatogenesis in mice. Biol Reprod 90, 3.
173. Kerr JB. (1988a) A light microscopic and morphometric analysis of the Sertoli cell during the spermatogenic cycle of the rat. Anat Embryol (Berl) 177, 341-348.
174. Kerr JB. (1988b) An ultrastructural and morphometric analysis of the Sertoli cell during the spermatogenic cycle of the rat. Anat Embryol (Berl) 179, 191-203.
175. Kerr JB. (1995) Macro, micro, and molecular research on spermatogenesis: the quest to understand its control. Microsc Res Tech 32, 364-384.
176. Kerr JB & De Kretser DM. (1975) Cyclic variations in Sertoli cell lipid content throughout the spermatogenic cycle in the rat. J Reprod Fertil 43, 1-8.
177. Kerr JB, Loveland KL, O'Bryan MK & de Kretser DM. (2006) Cytology of the testis and intrinsic control mechanisms. In: Kobil and Neill's Physiology of Reproduction, Vol. 1 (ed. JD Neill ), pp. 827-947. Elsevier, St. Louis, MO.
178. Ketola I, Rahman N, Toppari J, Bielinska M, Porter-Tinge SB, Tapanainen JS, Huhtaniemi IT, Wilson DB & Heikinheimo M. (1999) Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis. Endocrinology 140, 1470-1480.
179. Kierszenbaum AL. (1970) Effect of trenimon on the ultrastructure of Sertoli cells in the mouse. Virchows Arch B Cell Pathol 5, 1-12.
180. Kim KH & Wang Z. (1993) Action of vitamin A on the testis: role of the Sertoli cell. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 517-536. Cache River Press, Clearwater, FL.
181. Kobayashi T & Nagahama Y. (2009) Molecular aspects of gonadal differentiation in a teleost fish, the nile tilapia. Sex Dev 3, 108-117.
182. Kobayashi Y, Nakamura M, Sunobe T, Usami T, Kobayashi T, Manabe H, Paul-Prasanth B, Suzuki N & Nagahama Y. (2009) Sex change in the Gobiid fish is mediated through rapid switching of gonadotropin receptors from ovarian to testicular portion or vice versa. Endocrinology 150, 1503-1511.
183. Koopman P, Munsterberg A, Capel B, Vivian N & Lovell-Badge R. (1990) Expression of a candidate sex-determining gene during mouse testis differentiation. Nature 348, 450-452.
184. Kopera IA, Bilinska B, Cheng CY & Mruk DD. (2010) Sertoli-germ cell junctions in the testis: a review of recent data. Philos Trans R Soc Lond B Biol Sci 365, 1593-1605.
185. Kubota H, Avarbock MR & Brinster RL. (2004) Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. Proc Natl Acad Sci USA 101, 16489-16494.
186. Kubota H & Brinster RL. (2008) Culture of rodent spermatogonial stem cells, male germline stem cells of the postnatal animal. Methods Cell Biol 86, 59-84.
187. Kushida T, Iijima H, Nagato Y & Kushida H. (1993) Studies on thick sections of the nucleus of mouse Sertoli cells using an electron microscope operating at 300 kV. Okajimas Folia Anat Jpn 70, 41-50.
188. Kyronlahti A, Euler R, Bielinska M, Schoeller EL, Moley KH, Toppari J, Heikinheimo M & Wilson DB. (2011) GATA4 regulates Sertoli cell function and fertility in adult male mice. Mol Cell Endocrinol 333, 85-95.
189. Labrie F, Legace L, Ferland L, Kelly PA, Drouin J, Massicotte J, Bonne C, Raynaud JP & Dorrington JH. (1978) Interactions between LHRH, sex steroids and "Inhibin" in the control of LH and FSH secretion. Int J Androl 1, 81-89.
190. Lacerda SM, Costa GM, Campos-Junior PH, Segatelli TM, Yazawa R, Takeuchi Y, Morita T, Yoshizaki G & Franca LR. (2013) Germ cell transplantation as a potential biotechnological approach to fish reproduction. Fish Physiol Biochem 39, 3-11.
191. Lacerda SM, Costa GM & de Franca LR. (2014) Biology and identity of fish spermatogonial stem cell. Gen Comp Endocrinol 207, 56-65.
192. Lacroix M, Parvinen M & Fritz IB. (1981) Localization of testicular plasminogen activator in discrete portions (stage VII and VIII) of the seminiferous tubule. Biol Reprod 25, 143-146.
193. Leal MC, Cardoso ER, Nobrega RH, Batlouni SR, Bogerd J, Franca LR & Schulz RW. (2009) Histological and stereological evaluation of zebrafish (Danio rerio) spermatogenesis with an emphasis on spermatogonial generations. Biol Reprod 81, 177-187.
194. Leblond CP & Clermont Y. (1952) Definition of the stages of the cycle of the seminiferous epithelium in the rat. Ann N Y Acad Sci 55, 548-573.
195. Leichtmann-Bardoogo Y, Cohen LA, Weiss A, Marohn B, Schubert S, Meinhardt A & Meyron-Holtz EG. (2012) Compartmentalization and regulation of iron metabolism proteins protect male germ cells from iron overload. Am J Physiol Endocrinol Metab 302, E1519-E1530.
196. Li H, Papadopoulos V, Vidic B, Dym M & Culty M. (1997) Regulation of rat testis gonocyte proliferation by platelet-derived growth factor and estradiol: identification of signaling mechanisms involved. Endocrinology 138, 1289-1298.
197. Li N, Mruk DD & Cheng CY. (2015) Actin binding proteins in blood-testis barrier function. Curr Opin Endocrinol Diabetes Obes 22, 238-247.
198. Lie PP, Cheng CY & Mruk DD. (2013) Signalling pathways regulating the blood-testis barrier. Int J Biochem Cell Biol 45, 621-625.
199. Lie PP, Mruk DD, Lee WM & Cheng CY. (2010) Cytoskeletal dynamics and spermatogenesis. Philos Trans R Soc Lond B Biol Sci 365, 1581-1592.
200. Loveland KL & Hedger MP. (2015) Activins and inhibins in Sertoli cell biology: implications for testis development and function. In: Sertoli Cell Biology(ed. M Griswold ), pp. 201-232. Elsevier Academic Press, Oxford.
201. Loveland KL, Zlatic K, Stein-Oakley A, Risbridger G & deKretser DM. (1995) Platelet-derived growth factor ligand and receptor subunit mRNA in the Sertoli and Leydig cells of the rat testis. Mol Cell Endocrinol 108, 155-159.
202. Lu N, Sargent KM, Clopton DT, Pohlmeier WE, Brauer VM, McFee RM, Weber JS, Ferrara N, Silversides DW & Cupp AS. (2013) Loss of vascular endothelial growth factor A (VEGFA) isoforms in the testes of male mice causes subfertility, reduces sperm numbers, and alters expression of genes that regulate undifferentiated spermatogonia. Endocrinology 154, 4790-4802.
203. Lucas TF, Pimenta MT, Pisolato R, Lazari MF & Porto CS. (2011) 17beta-estradiol signaling and regulation of Sertoli cell function. Spermatogenesis 1, 318-324.
204. Lui WY & Cheng CY (2008) Transcription regulation in spermatogenesis. In: Molecular Mechanisms in Spermatogenesis (ed C Y Cheng ). Landes Bioscience and Springer Science+Business Media, Texas.
205. Lui WY & Cheng CY. (2012) Transcriptional regulation of cell adhesion at the blood-testis barrier and spermatogenesis in the testis. Adv Exp Med Biol 763, 281-294.
206. Lui WY, Mruk D, Lee WM & Cheng CY. (2003) Sertoli cell tight junction dynamics: their regulation during spermatogenesis. Biol Reprod 68, 1087-1097.
207. Lyon KRP, Bosseboeuf E & Vogl AW. (2015) An alternative model of tubulobulbar complex internalization during junction remodeling in the seminiferous epithelium of the rat testis. Biol Reprod 93, 1-11.
208. Magrek S & Jost A. (1991) Sertoli cells and testicular differentiation in the rat fetus. J Electron Microsc Tech 19, 172-188.
209. Mallidis C & Baker HW. (1994) Fine needle tissue aspiration biopsy of the testis. Fertil Steril 61, 367-375.
210. Mather JP, Gunsalus GL, Musto NA, Cheng CY, Parvinen M, Wright W, Perez-Infante V, Margioris A, Liotta A, Becker R, Krieger DT & Bardin CW. (1983) The hormonal and cellular control of Sertoli cell secretion. J Steroid Biochem 19, 41-51.
211. Matson CK, Murphy MW, Sarver AL, Griswold MD, Bardwell VJ & Zarkower D. (2011) DMRT1 prevents female reprogramming in the postnatal mammalian testis. Nature 476, 101-104.
212. Matta SL, Vilela DA, Godinho HP & Franca LR. (2002) The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model. Endocrinology 143, 970-978.
213. McClusky LM, Patrick S, Barnhoorn IE, van Dyk JC, de Jager C & Bornman MS. (2009) Immunohistochemical study of nuclear changes associated with male germ cell death and spermiogenesis. J Mol Histol 40, 287-299.
214. McGuinness MP & Griswold MD. (1994) Interactions between Sertoli cells and germ cells in the testis. Semin Dev Biol 5, 61-66.
215. McKinnell C, Brackenbury ET, Qureshi SJ, Hargreave TB & Sharpe RM. (1995) Comparative analysis of proteins secreted in vitro by isolated seminiferous tubules from man and the rat. Int J Androl 18, 103-111.
216. Means AR, Dedman JR, Tash JS, Tindall DJ, van Sickle M & Welsh MJ. (1980) Regulation of the testis sertoli cell by follicle stimulating hormone. Annu Rev Physiol 42, 59-70.
217. Means AR, Fakunding JL, Huckins C, Tindall DJ & Vitale R. (1976) Follicle-stimulating hormone, the Sertoli cell, and spermatogenesis. Recent Prog Horm Res 32, 477-527.
218. Meinhardt A & Hedger MP. (2011) Immunological, paracrine and endocrine aspects of testicular immune privilege. Mol Cell Endocrinol 335, 60-68.
219. Meistrich ML & Hess RA. (2013) Assessment of spermatogenesis through staging of seminiferous tubules. Methods Mol Biol 927, 299-307.
220. Melo MC, van Dijk P, Andersson E, Nilsen TO, Fjelldal PG, Male R, Nijenhuis W, Bogerd J, de Franca LR, Taranger GL & Schulz RW. (2015) Androgens directly stimulate spermatogonial differentiation in juvenile Atlantic salmon (Salmo salar). Gen Comp Endocrinol 211, 52-61.
221. Meng J, Greenlee AR, Taub CJ & Braun RE (2011) Sertoli cell-specific deletion of the androgen receptor compromises testicular immune privilege in mice. Biol Reprod 85, 254-260.
222. Meng J, Holdcraft RW, Shima JE, Griswold MD & Braun RE. (2005) Androgens regulate the permeability of the blood-testis barrier. Proc Natl Acad Sci USA 102, 16696-16700.
223. Meng X, Lindahl M, Hyvonen ME, Parvinen M, de Rooij DG, Hess MW, Raatikainen-Ahokas A, Sainio K, Rauvala H, Lakso M, Pichel JG, Westphal H, Saarma M & Sariola H. (2000) Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science 287, 1489-1493.
224. Miles DC, van den Bergen JA, Wakeling SI, Anderson RB, Sinclair AH & Western PS. (2012) The proto-oncogene Ret is required for male foetal germ cell survival. Dev Biol 365, 101-109.
225. Mital P, Hinton BT & Dufour JM. (2011) The blood-testis and blood-epididymis barriers are more than just their tight junctions. Biol Reprod 84, 851-858.
226. Mital P, Kaur G & Dufour J. (2010) Immunoprotective Sertoli cells: making allogeneic and xenogeneic transplantation feasible. Reproduction 139, 495-504.
227. Mital P, Kaur G & Dufour JM. (2010) Immunoprotective sertoli cells: making allogeneic and xenogeneic transplantation feasible. Reproduction 139, 495-504.
228. Miura C, Ohta T, Ozaki Y, Tanaka H & Miura T. (2009) Trypsin is a multifunctional factor in spermatogenesis. Proc Natl Acad Sci USA 106, 20972-20977.
229. Miura T, Ohta T, Miura CI & Yamauchi K. (2003) Complementary deoxyribonucleic acid cloning of spermatogonial stem cell renewal factor. Endocrinology 144, 5504-5510.
230. Molyneaux KA, Zinszner H, Kunwar PS, Schaible K, Stebler J, Sunshine MJ, O'Brien W, Raz E, Littman D, Wylie C & Lehmann R. (2003) The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival. Development 130, 4279-4286.
231. Monesi V. (1965) Synthetic activities during spermatogenesis in the mouse RNA and protein. Exp Cell Res 39, 197-224.
232. Montgomery JTH (1911) Differentiation of the human cells of Sertoli. Biol Bull 21, 367-388.
233. Morais RD, Nóbrega RH, Gómez-González NE, Schmidt R, Bogerd J, Franca LR & Schulz RW. (2013) Thyroid hormone stimulates the proliferation of Sertoli cells and single type A spermatogonia in adult zebrafish (Danio rerio) testis. Endocrinology 154, 4365-4376.
234. Morales C & Clermont Y. (1993) Structural changes of the Sertoli cell during the cycle of the seminiferous epithelium. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 305-329. Cache River Press, Clearwater, FL.
235. Morales C & Griswold MD. (1987) Retinol-induced stage synchronization in seminiferous tubules of the rat. Endocrinology 121, 432-434.
236. Morrow CM, Tyagi G, Simon L, Carnes K, Murphy KM, Cooke PS, Hofmann MC & Hess RA. (2009) Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod 81, 871-879.
237. Mosher KI, Andres RH, Fukuhara T, Bieri G, Hasegawa-Moriyama M, He Y, Guzman R & Wyss-Coray T. (2012) Neural progenitor cells regulate microglia functions and activity. Nat Neurosci 15, 1485-1487.
238. Mruk DD (2015) Emergent roles for intercellular adhesion molecule-1 in the restructuring of the blood-testis barrier during spermatogenesis in the mammal. Histol Histopathol 31, 159-166.
239. Mruk DD & Cheng CY. (2004a) Cell-cell interactions at the ectoplasmic specialization in the testis. Trends Endocrinol Metab 15, 439-447.
240. Mruk DD & Cheng CY. (2004b) Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 25, 747-806.
241. Mruk DD & Cheng CY. (2010) Tight junctions in the testis: new perspectives. Philos Trans R Soc Lond B Biol Sci 365, 1621-1635.
242. Mruk DD & Cheng CY. (2015) The mammalian blood-testis barrier: its biology and regulation. Endocr Rev 36, 564-591.
243. Mulholland DJ, Dedhar S & Vogl AW. (2001) Rat seminiferous epithelium contains a unique junction (Ectoplasmic specialization) with signaling properties both of cell/cell and cell/matrix junctions. Biol Reprod 64, 396-407.
244. Mullaney BP & Skinner MK. (1991) Growth factors as mediators of testicular cell-cell interactions. Baillieres Clin Endocrinol Metab 5, 771-790.
245. Mullaney BP & Skinner MK. (1992) Basic fibroblast growth factor (bFGF) gene expression and protein production during pubertal development of the seminiferous tubule: follicle-stimulating hormone-induced Sertoli cell bFGF expression. Endocrinology 131, 2928-2934.
246. Murphy CJ & Richburg JH. (2014) Implications of Sertoli cell induced germ cell apoptosis to testicular pathology. Spermatogenesis 4, e979110.
247. Nagano M, Ryu BY, Brinster CJ, Avarbock MR & Brinster RL. (2003) Maintenance of mouse male germ line stem cells in vitro. Biol Reprod 68, 2207-2214.
248. Nakajima S, Hayashi M, Kouguchi T, Yamaguchi K, Miwa M & Yoshizaki G. (2014) Expression patterns of gdnf and gfralpha1 in rainbow trout testis. Gene Expr Patterns 14, 111-120.
249. Nalbandian A, Dettin L, Dym M & Ravindranath N. (2003) Expression of vascular endothelial growth factor receptors during male germ cell differentiation in the mouse. Biol Reprod 69, 985-994.
250. Naughton CK, Jain S, Strickland AM, Gupta A & Milbrandt J. (2006) Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate. Biol Reprod 74, 314-321.
251. Negrini F, Pugliese A, Ferrari A & Sertoli E. (1908) Onoranze al Prof. Enrico Sertoli. La Clinica Veterinaria 31, 49-62.
252. Nicander L. (1967) An electron microscopical study of cell contacts in the seminiferous tubules of some mammals. Z Zellforsch Mikrosk Anat 83, 375-397.
253. Nicholls PK, Stanton PG, Chen JL, Olcorn JS, Haverfield JT, Qian H, Walton KL, Gregorevic P & Harrison CA. (2012) Activin signaling regulates Sertoli cell differentiation and function. Endocrinology 153, 6065-6077.
254. Nikolova DB, Martinova YS, Seidensticker M & Bellve AR. (1997) Leukaemia inhibitory factor stimulates proliferation of prospermatogonial stem cells. Reprod Fertil Dev 9, 717-721.
255. Nitta T, Hata M, Gotoh S, Seo Y, Sasaki H, Hashimoto N, Furuse M & Tsukita S. (2003) Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol 161, 653-660.
256. Nóbrega RH, de Souza Morais RD, Crespo D, de Waal PP, de França LR, Schulz RW & Bogerd J (2015) Fsh stimulates spermatogonial proliferation and differentiation in zebrafish via Igf3. Endocrinology 156, 3804-3817.
257. Nóbrega RH, Greebe CD, van de Kant H, Bogerd J, de França LR & Schulz RW. (2010) Spermatogonial stem cell niche and spermatogonial stem cell transplantation in zebrafish. PLoS ONE 5(9).
258. O'Donnell L, Nicholls PK, O'Bryan MK, McLachlan RI & Stanton PG. (2011) Spermiation: the process of sperm release. Spermatogenesis 1, 14-35.
259. O'Donnell L & O'Bryan MK. (2014) Microtubules and spermatogenesis. Semin Cell Dev Biol 30, 45-54.
260. O'Rand MG & Romrell LJ. (1977) Appearance of cell surface auto- and isoantigens during spermatogenesis in the rabbit. Dev Biol 55, 347-358.
261. Oatley JM & Brinster RL. (2012) The germline stem cell niche unit in mammalian testes. Physiol Rev 92, 577-595.
262. Oatley MJ, Racicot KE & Oatley JM. (2011) Sertoli cells dictate spermatogonial stem cell niches in the mouse testis. Biol Reprod 84, 639-645.
263. Oliveira PF, Martins AD, Moreira AC, Cheng CY & Alves MG. (2015) The Warburg effect revisited-lesson from the Sertoli cell. Med Res Rev 35, 126-151.
264. Orth J. (1982) Proliferation of Sertoli cells in fetal and postnatal rats: a quantitative autoradiographic study. Anat Rec 203, 485-492.
265. Orth JM. (1984) The role of follicle-stimulating hormone in controlling Sertoli cell proliferation in testes of fetal rats. Endocrinology 115, 1248-1255.
266. Orth JM, Jester WF, Li LH & Laslett AL. (2000) Gonocyte-Sertoli cell interactions during development of the neonatal rodent testis. Curr Top Dev Biol 50, 103-124.
267. Parvinen M. (1982) Regulation of the seminiferous epithelium. Endocr Rev 3, 404-417.
268. Parvinen M. (1993) Cyclic function of Sertoli cells. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 39-86. Cache River Press, Clearwater, FL.
269. Parvinen M & Vanha-Perttula T. (1972) Identification and enzyme quantitation of the stages of the seminiferous epithelial wave in the rat. Anat Rec 174, 435-449.
270. Parvinen M, Vihko KK & Toppari J. (1986) Cell interactions during the seminiferous epithelial cycle. Int Rev Cytol 104, 115-151.
271. Pawar HS & Wrobel KH. (1991) Quantitative aspects of water buffalo (Bubalus bubalis) spermatogenesis. Arch Histol Cytol 54, 491-509.
272. Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA & Braun RE. (2010) Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells 28, 1424-1434.
273. Pelletier J, Schalling M, Buckler AJ, Rogers A, Haber DA & Housman D. (1991) Expression of the Wilms' tumor gene WT1 in the murine urogenital system. Genes Dev 5, 1345-1356.
274. Pelletier RM. (1986) Cyclic formation and decay of the blood-testis barrier in the mink (Mustela vison), a seasonal breeder. Am J Anat 175, 91-117.
275. Pelletier RM. (2011) The blood-testis barrier: the junctional permeability, the proteins and the lipids. Prog Histochem Cytochem 46, 49-127.
276. Pelletier RM & Byers SW. (1992) The blood-testis barrier and Sertoli cell junctions: structural considerations. Microsc Res Tech 20, 3-33.
277. Pelliniemi LJ, KFrojdman K & Paranko J (1993) Embryological and prenatal development and function of Sertoli cells. In: The Sertoli Cell (eds L D Russell & M D Griswold ), pp. 87-113. Cache River Press, Clearwater, FL.
278. Pesce M, Farrace MG, Piacentini M, Dolci S & De Felici M. (1993) Stem cell factor and leukemia inhibitory factor promote primordial germ cell survival by suppressing programmed cell death (apoptosis). Development 118, 1089-1094.
279. Picard JY & Josso N. (1984) Purification of testicular anti-Mullerian hormone allowing direct visualization of the pure glycoprotein and determination of yield and purification factor. Mol Cell Endocrinol 34, 23-29.
280. Piquet-Pellorce C, Dorval-Coiffec I, Pham MD & Jegou B. (2000) Leukemia inhibitory factor expression and regulation within the testis. Endocrinology 141, 1136-1141.
281. Pitetti JL, Calvel P, Zimmermann C, Conne B, Papaioannou MD, Aubry F, Cederroth CR, Urner F, Fumel B, Crausaz M, Docquier M, Herrera PL, Pralong F, Germond M, Guillou F, Jegou B & Nef S. (2013) An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice. Mol Endocrinol 27, 814-827.
282. Prat F, Sumpter JP & Tyler CR. (1996) Validation of radioimmunoassays for two salmon gonadotropins (GTH I and GTH II) and their plasma concentrations throughout the reproductivecycle in male and female rainbow trout (Oncorhynchus mykiss). Biol Reprod 54, 1375-1382.
283. Pudney J. (1993) Comparative cytology of the non-mammalian Sertoli cell. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 611-658. Cache River Press, Clearwater, FL.
284. Qian X, Mruk DD, Cheng YH, Tang EI, Han D, Lee WM, Wong EW & Cheng CY (2014) Actin binding proteins, spermatid transport and spermiation. Semin Cell Dev Biol 30, 75-85.
285. Ramaiah M & Wilkinson MF. (2015) MicroRNAs and Sertoli cells. In: Sertoli Cell Biology (ed. M Griswold ), pp. 307-332. Elsevier Academic Press, Oxford.
286. Rambourg A, Clermont Y & Hermo L. (1979) Three-dimensional architecture of the golgi apparatus in Sertoli cells of the rat. Am J Anat 154, 455-476.
287. Rato L, Socorro S, Cavaco JE & Oliveira PF. (2010) Tubular fluid secretion in the seminiferous epithelium: ion transporters and aquaporins in Sertoli cells. J Membr Biol 236, 215-224.
288. Raymond CS, Kettlewell JR, Hirsch B, Bardwell VJ & Zarkower D. (1999) Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development. Dev Biol 215, 208-220.
289. Raymond CS, Shamu CE, Shen MM, Seifert KJ, Hirsch B, Hodgkin J & Zarkower D. (1998) Evidence for evolutionary conservation of sex-determining genes. Nature 391, 691-695.
290. Regaud C. (1899) Sur la morphologie de la cellule de Sertoli et sur son role dans la spermatogénese chez les mammiféres. Comptes rendus de l'Association des anatomistes 1, 21-31.
291. Regaud CL. (1901) Études sur la structure des tubes séminifères et sur la spermatogénèse chez les mammifères. Archives d'Anatomie Microscopique 4, 101-156.
292. Reis MM, Moreira AC, Sousa M, Mathur PP, Oliveira PF & Alves MG. (2015) Sertoli cell as a model in male reproductive toxicology: advantages and disadvantages. J Appl Toxicol 35, 870-883.
293. Rich KA & de Kretser DM. (1983) Spermatogenesis and the Sertoli cell. In: The Pituitary and Testis: Clinical and Experimental Studies (eds. DM de Kretser, HG Burger & B Hudson ), pp. 84-105. Springer-Verlag, New York.
294. Ritzen EM, Boitani C, Parvinen M, French FC & Feldman M. (1982) Stage-dependent secretion of ABP by rat seminiferous tubules. Mol Cell Endocrinol 25, 25-33.
295. Ritzén EM, Hansson V & French FS. (1981) The Sertoli cell. In: The Testis (eds. HG Burger & D de Kretser ), pp. 171-194. Raven Press, New York.
296. Rival C, Lustig L, Iosub R, Guazzone VA, Schneider E, Meinhardt A & Fijak M. (2006) Identification of a dendritic cell population in normal testis and in chronically inflamed testis of rats with autoimmune orchitis. Cell Tissue Res 324, 311-318.
297. Rivas B, Huang Z & Agoulnik AI. (2014) Normal fertility in male mice with deletion of beta-catenin gene in germ cells. Genesis 52, 328-332.
298. Robaire B & Bayly SF. (1989) Testicular signaling: incoming and outgoing messages. Ann N Y Acad Sci 564, 250-260.
299. Roosen-Runge EC. (1955) Quantitative studies on spermatogenesis in the albino rat. III. Volume changes in the cells of the seminiferous tubules. Anat Rec 123, 385-398.
300. Rothbarth K, Kempf T, Juodka B, Glaser T, Stammer H & Werner D. (2001) Intracellular location and nuclear targeting of the Spi-1, Spi-2 and Spi-3 gene-derived serine protease inhibitors in non-secretory cells. Eur J Cell Biol 80, 341-348.
301. Russell L. (1977) Observations on rat Sertoli ectoplasmic ('junctional') specializations in their association with germ cells of the rat testis. Tissue Cell 9, 475-498.
302. Russell L & Clermont Y. (1976) Anchoring device between Sertoli cells and late spermatids in rat seminiferous tubules. Anat Rec 185, 259-278.
303. Russell L, Myers P, Ostenburg J & Malone J. (1987) Sertoli ectoplasmic specializations during spermatogenesis. Ann N Y Acad Sci 513, 55-64.
304. Russell LD. (1980) Sertoli-germ cell interactions: a review. Gamete Res 3, 179-202.
305. Russell LD. (1984) Spermiation - the sperm release process: ultrastructural observations and unresolved problems. In: Electron Microscopy in Biology and Medicine, Vol. 2 (eds. J Van Blerkom & PM Motta ), pp. 46-66. Martinus Nijhoff, Boston, MA.
306. Russell LD. (1993a) Form, dimensions, and cytology of mammalian Sertoli cells. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 1-37. Cache River Press, Clearwater, FL.
307. Russell LD. (1993b) Morphological and functional evidence for Sertoli-germ cell relationships. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 365-390. Cache River Press, Clearwater, FL.
308. Russell LD. (1993c) Role in spermiation. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 269-304. Cache River Press, Clearwater, FL.
309. Russell LD & Clermont Y. (1977) Degeneration of germ cells in normal, hypophysectomized and hormone treated hypophysectomized rats. Anat Rec 187, 347-366.
310. Russell LD, Ettlin RA, Sinha Hikim AP & Clegg ED (1990a) Histological and Histopathological Evaluation of the Testis. Cache River Press, Clearwater, 286p.
311. Russell LD, Gardner RJ & Weber JE. (1986) Reconstruction of a type-B configuration monkey Sertoli cell: size, shape, and configurational and specialized cell-to-cell relationships. Am J Anat 175, 73-90.
312. Russell LD & Griswold MD (1993a) Preface. In: The Sertoli Cell (eds L D Russell & M D Griswold ), pp. ix-xi. Cache River Press, Clearwater, FL.
313. Russell LD & Griswold MD (1993b) (eds) The Sertoli Cell. Cache River Press, Clearwater, FL, 801p.
314. Russell LD, Myer P, Ostenburg J & Malone J. (1980) Sertoli ectoplasmic specializations during spermatogenesis. In: Testicular Development, Structure, and Function (eds. A Steinberger & E Steinberger ), pp. 55-63. Raven Press, New York.
315. Russell LD & Peterson RN. (1985) Sertoli cell junctions: morphological and functional correlates. Int Rev Cytol 94, 177-211.
316. Russell LD, Ren HP, Sinha Hikim I, Schulze W & Sinha Hikim AP. (1990b) A comparative study in twelve mammalian species of volume densities, volumes, and numerical densities of selected testis components, emphasizing those related to the Sertoli cell. Am J Anat 188, 21-30.
317. Russell LD, Saxena NK & Turner TT. (1989) Cytoskeletal involvement in spermiation and sperm transport. Tissue Cell 21, 361-379.
318. Russell LD & Steinberger A. (1989) Sertoli cells in culture: views from the perspectives of an in vivoist and an in vitroist. Biol Reprod 41, 571-577.
319. Russell LD, Tallon-Doran M, Weber JE, Wong V & Peterson RN. (1983) Three-dimensional reconstruction of a rat stage V Sertoli cell: III. A study of specific cellular relationships. Am J Anat 167, 181-192.
320. Ryu BY, Orwig KE, Oatley JM, Avarbock MR & Brinster RL. (2006) Effects of aging and niche microenvironment on spermatogonial stem cell self-renewal. Stem Cells 24, 1505-1511.
321. Saitou M, Furuse M, Sasaki H, Schulzke JD, Fromm M, Takano H, Noda T & Tsukita S. (2000) Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell 11, 4131-4142.
322. Sakaguchi T, Nishimoto M, Miyagi S, Iwama A, Morita Y, Iwamori N, Nakauchi H, Kiyonari H, Muramatsu M & Okuda A. (2006) Putative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Mol Cell Biol 26, 6557-6570.
323. Sanborn BM, Caston LA, Buzek SW & Ussuf KK. (1987) Hormonal regulation of Sertoli cell function. Adv Exp Med Biol 219, 561-588.
324. Sanborn BM, Elkington ISH, Steinberger A, Steinberger E & Meistrich ML. (1975) Androgen binding in the testis: in vitro production of androgen binding protein (ABP) by Sertoli cell cultures and measurement of nuclear bound androgen by a nuclear exhange assay. In: Hormonal Regulation of Spermatogenesis (eds. F French, V Hansson, E Ritzen & S Nayfeh ), pp. 293-310. Plenum, New York.
325. Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD & McKnight GS. (2013) RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo. PLoS ONE 8, e66179.
326. Sar M, Hall SH, Wilson EM & French FS. (1993) Androgen regulation of Sertoli cells. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 509-516. Cache River Press, Clearwater, FL.
327. Sar M, Lubahn DB, French FS & Wilson EM. (1990) Immunohisto-chemical localization of the androgen receptor in rat and human tissues. Endocrinology 127, 3180-3186.
328. Sato T, Aiyama Y, Ishii-Inagaki M, Hara K, Tsunekawa N, Harikae K, et al. (2011a) Cyclical and patch-like GDNF distribution along the basal surface of Sertoli cells in mouse and hamster testes. PLoS ONE 6, e28367.
329. Sato T, Katagiri K, Gohbara A, Inoue K, Ogonuki N, Ogura A, Kubota Y & Ogawa T. (2011b) In vitro production of functional sperm in cultured neonatal mouse testes. Nature 471, 504-507.
330. Scadden DT. (2006) The stem-cell niche as an entity of action. Nature 441, 1075-1079.
331. Schulz RW, de Franca LR, Lareyre JJ, Le Gac F, Chiarini-Garcia H, Nobrega RH & Miura T. (2010) Spermatogenesis in fish. Gen Comp Endocrinol 165, 390-411.
332. Schulz RW, Menting S, Bogerd J, Franca LR, Vilela DA & Godinho HP. (2005) Sertoli cell proliferation in the adult testis-evidence from two fish species belonging to different orders. Biol Reprod 73, 891-898.
333. Schulz RW, van Dijk W, Chaves-Pozo E, Garcia-Lopez A, de Franca LR & Bogerd J. (2012) Sertoli cell proliferation in the adult testis is induced by unilateral gonadectomy in African catfish. Gen Comp Endocrinol 177, 160-167.
334. Schulze C & Holstein AF. (1993a) Human Sertoli cell structure. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 685-702. Cache River Press, Clearwater, FL.
335. Schulze C & Holstein AF. (1993b) Human Sertoli cells under pathological conditions. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 597-610. Cache River Press, Clearwater, FL.
336. Schulze C, Holstein AF, Schirren C & Korner F. (1976) On the morphology of the human Sertoli cells under normal conditions and in patients with impaired fertility. Andrologia 8, 167-178.
337. Sekido R & Lovell-Badge R. (2008) Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer. Nature 453, 930-934.
338. Selawry HP. (1994) Islet transplantation to immuneprivilged sites. In: Pancreatic Islet Transplantation: Immunomodulation of Pancreatic Islets (eds. RP Lanza & WL Chick ), pp. 75-86. Landes/CRC Press, Austin, TX.
339. Selawry HP & Cameron DF. (1993) Sertoli cell-enriched fractions in successful islet cell transplantation. Cell Transplant 2, 123-129.
340. Sertoli E. (1865) Dell'esistenza di particolari cellule ramificate nei canalicoli seminiferi del testicolo umano. Morgagni 7, 31-40.
341. Setchell BP. (1967) The blood-testicular fluid barrier in sheep. J Physiol 189, 63-65.
342. Setchell BP. (1970) The secretion of fluid by the testes of rats, rams and goats with some observations on the effect of age, cryptorchidism and hypophysectomy. J Reprod Fert 23, 79-85.
343. Setchell BP. (1974) Secretions of the testis and epididymis. J Reprod Fertil 37, 165-177.
344. Setchell BP. (1990) The testis and tissue transplantation: historical aspects. J Reprod Immunol 18, 1-8.
345. Setchell BP, Davies RV, Gladwell RT, Hinton BT, Main SJ, Pilsworth L & Waites GMH. (1978) The movement of fluid in the seminiferous tubules and rete testis. Ann Biol Anim biochem Biophys 18, 623-632.
346. Setchell BP, Dawson RM & White RW. (1968) The high concentration of free myo-inositol in rete testis fluid from rams. J Reprod Fertil 17, 219-220.
347. Setchell BP & Main SJ. (1975) The blood - testis barrier and steroids. Curr Top Mol Endocrinol 2, 223-233.
348. Shao M, Ghosh A, Cooke VG, Naik UP & Martin-DeLeon PA. (2008) JAM-A is present in mammalian spermatozoa where it is essential for normal motility. Dev Biol 313, 246-255.
349. Sharpe R. (1993) Experimental evidence for Sertoli-germ cell and Sertoli-Leydig cell interactions. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 391-418. Cache River Press, Clearwater, FL.
350. Sharpe R. (1994) Regulation of spermatogenesis. In: The Physiology of Reproduction, Vol. 2 (eds. E Knobil & J Neill ), pp. 1363-1434. Raven Press, New York.
351. Sharpe RM. (1988) Bidirectional secretion by the Sertoli cell. Int J Androl 11, 87-91.
352. Sharpe RM. (1992) Monitoring of spermatogenesis in man-measurement of Sertoli cell- or germ cell-secreted proteins in semen or blood [editorial]. Int J Androl 15, 201-210.
353. Sharpe RM, McKinnell C, Kivlin C & Fisher JS. (2003) Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction 125, 769-784.
354. Shibata N & Hamaguchi S. (1988) Evidence for the sexual bipotentiality of spermatogonia in the fish, Oryzias latipes. J Exp Zool 245, 71-77.
355. Shima JE, McLean DJ, McCarrey JR & Griswold MD. (2004) The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod 71, 319-330.
356. Shinohara T, Avarbock MR & Brinster RL. (1999) Beta1- and alpha6-integrin are surface markers on mouse spermatogonial stem cells. Proc Natl Acad Sci USA 96, 5504-5509.
357. Shinohara T, Orwig KE, Avarbock MR & Brinster RL. (2001) Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility. Proc Natl Acad Sci USA 98, 6186-6191.
358. Silva CA, Cocuzza M, Carvalho JF & Bonfa E. (2014) Diagnosis and classification of autoimmune orchitis. Autoimmun Rev 13, 431-434.
359. Silva FR, Leite LD & Wassermann GF. (2002) Rapid signal transduction in Sertoli cells. Eur J Endocrinol 147, 425-433.
360. Simon L, Ekman GC, Garcia T, Carnes K, Zhang Z, Murphy T, Murphy KM, Hess RA, Cooke PS & Hofmann MC. (2010) ETV5 regulates sertoli cell chemokines involved in mouse stem/progenitor spermatogonia maintenance. Stem Cells 28, 1882-1892.
361. Simon L, Ekman GC, Tyagi G, Hess RA, Murphy KM & Cooke PS. (2007) Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, Sertoli cell proteins essential for spermatogonial stem cell maintenance. Exp Cell Res 313, 3090-3099.
362. Sinha Hikim A, Amador A, Klemcke H, Bartke A & Russell L. (1989) Correlative morphology and endocrinology of Sertoli cells in hamster testes in active and inactive states of spermatogenesis. Endocrinology 125, 1829-1843.
363. Siu MK & Cheng CY. (2009) Extracellular matrix and its role in spermatogenesis. Adv Exp Med Biol 636, 74-91.
364. Skaar KS, Nobrega RH, Magaraki A, Olsen LC, Schulz RW & Male R. (2011) Proteolytically activated, recombinant anti-mullerian hormone inhibits androgen secretion, proliferation, and differentiation of spermatogonia in adult zebrafish testis organ cultures. Endocrinology 152, 3527-3540.
365. Skinner MK. (1987) Cell-cell interactions in the testis. Ann N Y Acad Sci 513, 158-171.
366. Skinner MK. (1993a) Secretion of growth factors and other regulatory factors. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 237-248. Cache River Press, Clearwater, FL.
367. Skinner MK. (1993b) Setoli cell-peritubular myoid cell interactions. In: The Sertoli Cell (eds. MD Griswold & LD Russell ), pp. 477-484. Cache River Press, Clearwater, FL.
368. Skinner MK & Griswold MD. (1980) Sertoli cells synthesize and secrete transferrin-like protein. J Biol Chem 255, 9523-9525.
369. Skinner MK & Griswold MD. (1982) Secretion of testicular transferrin by cultured Sertoli cells is regulated by hormones and retinoids. Biol Reprod 27, 211-221.
370. Skinner MK & Griswold MD. (1983) Sertoli cells synthesize and secrete a ceruloplasmin-like protein. Biol Reprod 28, 1225-1229.
371. Skinner MK & Griswold MD (2005) (eds) Sertoli Cell Biology. Elsevier Academic Press, San Diego, 494p.
372. Skinner MK, Takacs K & Coffey RJ. (1989) Transforming growth factor-alpha gene expression and action in the seminiferous tubule: peritubular cell-Sertoli cell interactions. Endocrinology 124, 845-854.
373. Smith BE & Braun RE. (2012) Germ cell migration across Sertoli cell tight junctions. Science 338, 798-802.
374. Smith EP, Hall SH, Monaco L, French FS, Wilson EM & Conti M. (1989) A rat Sertoli cell factor similar to basic fibroblast growth factor increases c-fos messenger ribonucleic acid in cultured Sertoli cells. Mol Endocrinol 3, 954-961.
375. Smith LB & Walker WH (2014) The regulation of spermatogenesis by androgens. Semin Cell Dev Biol 30, 2-13.
376. Smith LB, Walker WH & O'Donnell L. (2015) Hormonal regulation of spermatogenesis through Sertoli cells by androgens and estrogens. In: Sertoli Cell Biology(ed. M Griswold ), pp. 175-200. Elsevier Academic Press, Oxford.
377. Snyder EM, Small C & Griswold MD. (2010) Retinoic acid availability drives the asynchronous initiation of spermatogonial differentiation in the mouse. Biol Reprod 83, 783-790.
378. Sowa Y, Imura T, Numajiri T, Nishino K & Fushiki S. (2012) Adipose-derived stem cells produce factors enhancing peripheral nerve regeneration: influence of age and anatomic site of origin. Stem Cells Dev 21, 1852-1862.
379. Spradling A, Drummond-Barbosa D & Kai T. (2001) Stem cells find their niche. Nature 414, 98-104.
380. Statter MB, Fahrner KJ, Barksdale EM Jr, Parks DE, Flavell RA & Donahoe PK. (1989) Correlation of fetal kidney and testis congenic graft survival with reduced major histocompatibility complex burden. Transplantation 47, 651-660.
381. Steinberger A (1979) Inhibin production by Sertoli cells in culture. J Reprod Fertil Suppl 26, 31-45.
382. Steinberger A & Jakubowiak A. (1993) Sertoli cell culture: historical perspective and review of methods. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 155-180. Cache River Press, Clearwater, FL.
383. Steinberger A & Steinberger E. (1970) Tissue culture of male mammalian gonads. In Vitro 5, 17-27.
384. Steinberger A & Steinberger E. (1987) (eds) Testicular Development, Structure, and Function. Raven Press, New York, 536p.
385. Steinberger A, Steinberger E & Perloff WH. (1964) Mammalian testes in organ culture. Exp Cell Res 36, 19-27.
386. Steinberger E. (1975) Hormonal regulation of the seminiferous tubule function. Curr Top Mol Endocrinol 2, 337-352.
387. Su W, Mruk DD & Cheng CY. (2013) Regulation of actin dynamics and protein trafficking during spermatogenesis-insights into a complex process. Crit Rev Biochem Mol Biol 48, 153-172.
388. Svingen T & Koopman P. (2013) Building the mammalian testis: origins, differentiation, and assembly of the component cell populations. Genes Dev 27, 2409-2426.
389. Sylvester SR. (1993) Secretion of transport and binding proteins. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 201-216. Cache River Press, Clearwater, FL.
390. Sylvester SR & Griswold MD. (1994) The testicular iron shuttle: a "nurse" function of the Sertoli cells. J Androl 15, 381-385.
391. Tadokoro Y, Yomogida K, Ohta H, Tohda A & Nishimune Y. (2002) Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway. Mech Dev 113, 29-39.
392. Takashima S, Kanatsu-Shinohara M, Tanaka T, Morimoto H, Inoue K, Ogonuki N, Jijiwa M, Takahashi M, Ogura A & Shinohara T. (2015) Functional differences between GDNF-dependent and FGF2-dependent mouse spermatogonial stem cell self-renewal. Stem Cell Reports 4, 489-502.
393. Tarulli GA, Stanton PG & Meachem SJ. (2012) Is the adult Sertoli cell terminally differentiated? Biol Reprod 87, 11-11.
394. Teilum G. (1949) Estrogen-producing Sertoli cell tumors (androblastoma tubulare lipoides) of the human testis and ovary; homologous ovarian and testicular tumors. J Clin Endocrinol Metab 9, 301-318.
395. Thuillier R, Mazer M, Manku G, Boisvert A, Wang Y & Culty M. (2010) Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation. Biol Reprod 82, 825-836.
396. Thuillier R, Wang Y & Culty M. (2003) Prenatal exposure to estrogenic compounds alters the expression pattern of platelet-derived growth factor receptors alpha and beta in neonatal rat testis: identification of gonocytes as targets of estrogen exposure. Biol Reprod 68, 867-880.
397. Tindall DJ, Rowley DR & Lipshultz LI. (1983) Sertoli cell structure and function in vivo and in vitro. In: Infertility in the Male (eds. LI Lipshultz & SS Howards ), pp. 71-98. Churchill Livingstone, New York.
398. Tindall DJ, Rowley DR, Murthy L, Lipshultz LI & Chang CH. (1985) Structure and biochemistry of the Sertoli cell. Int Rev Cytol 94, 127-149.
399. Tindall DJ, Vitale R & Means AR. (1975) Androgen binding protein as a biochemical marker of formation of the blood-testis barrier. Endocrinology 97, 636-648.
400. Toppari J, Kangasniemi M, Kaipia A, Mali P, Huhtaniemi I & Parvinen M. (1991) Stage- and cell-specific gene expression and hormone regulation of the seminiferous epithelium. J Electron Microsc Tech 19, 203-214.
401. Toyama Y, Maekawa M & Yuasa S. (2003) Ectoplasmic specializations in the Sertoli cell: new vistas based on genetic defects and testicular toxicology. Anat Sci Int 78, 1-16.
402. Tung PS, Dorrington IH & Fritz IB. (1975) Responsiveness of cultured Sertoli cells to FSH. Proc Natl Acad Sci USA 72, 1838-1842.
403. Tung PS & Fritz IB. (1978) Specific surface antigens on rat pachytene spermatocytes and successive classes of germinal cells. Dev Biol 64, 297-315.
404. Tung PS, Skinner MK & Fritz IB. (1984) Cooperativity between Sertoli cells and peritubular myoid cells in the formation of the basal lamina in the seminiferous tubule. Ann N Y Acad Sci 438, 435-446.
405. Ueno H & Mori H. (1990) Morphometrical analysis of Sertoli cell ultrastructure during the seminiferous epithelial cycle in rats. Biol Reprod 43, 769-776.
406. Van Dissel-Emiliani FM, De Boer-Brouwer M & De Rooij DG. (1996) Effect of fibroblast growth factor-2 on Sertoli cells and gonocytes in coculture during the perinatal period. Endocrinology 137, 647-654.
407. van Haaster LH, de Jong FH, Docter R & de Rooij DG. (1993) High neonatal triiodothyronine levels reduce the period of Sertoli cell proliferation and accelerate tubular lumen formation in the rat testis, and increase serum inhibin levels. Endocrinology 133, 755-760.
408. Viger RS, Mertineit C, Trasler JM & Nemer M. (1998) Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Mullerian inhibiting substance promoter. Development 125, 2665-2675.
409. Vilela DAR, Silva SGB, Peixoto MTD, Godinho HP & França LR. (2003) Spermatogenesis in teleost; insights from the Nile tilapia (Oreochromis niloticus) model. Fish Physiol Biochem 28, 187-190.
410. Vogl AW. (1988) Changes in the distribution of microtubules in rat Sertoli cells during spermatogenesis. Anat Rec 222, 34-41.
411. Vogl AW. (1989) Distribution and function of organized concentrations of actin filaments in mammalian spermatogenic cells and Sertoli cells. Int Rev Cytol 119, 1-56.
412. Vogl AW, Du M, Wang XY & Young JS. (2014) Novel clathrin/actin-based endocytic machinery associated with junction turnover in the seminiferous epithelium. Semin Cell Dev Biol 30, 55-64.
413. Vogl AW, Lin YC, Dym M & Fawcett DW. (1983a) Sertoli cells of the golden-mantled ground squirrel (Spermophilus lateralis): a model system for the study of shape change. Am J Anat 168, 83-98.
414. Vogl AW, Linck RW & Dym M. (1983b) Colchicine-induced changes in the cytoskeleton of the golden-mantled ground squirrel (Spermophilus lateralis) Sertoli cells. Am J Anat 168, 99-108.
415. Vogl AW, Pfeiffer DC, Mulholland D, Kimel G & Guttman J. (2000) Unique and multifunctional adhesion junctions in the testis: ectoplasmic specializations. Arch Histol Cytol 63, 1-15.
416. Vogl AW, Pfeiffer DC & Redenbach DM. (1991) Ectoplasmic ("junctional") specializations in mammalian Sertoli cells: influence on spermatogenic cells. Ann N Y Acad Sci 637, 175-202.
417. Vogl AW, Pfeiffer DC, Redenbach DM & Grove BD. (1993) Sertoli cell cytoskeleton. In: The Sertoli Cell (eds. LD Russell & MD Griswold ), pp. 39-86. Cache River Press, Clearwater, FL.
418. Vogl AW & Soucy LJ. (1985) Arrangement and possible function of actin filament bundles in ectoplasmic specializations of ground squirrel Sertoli cells. J Cell Biol 100, 814-825.
419. Vogl AW, Vaid KS & Guttman JA. (2008) The Sertoli cell cytoskeleton. Adv Exp Med Biol 636, 186-211.
420. Vogl AW, Weis M & Pfeiffer DC. (1995) The perinuclear centriole-containing centrosome is not the major microtubule organizing center in Sertoli cells. Eur J Cell Biol 66, 165-179.
421. Vogl AW, Young JS & Du M. (2013) New insights into roles of tubulobulbar complexes in sperm release and turnover of blood-testis barrier. Int Rev Cell Mol Biol 303, 319-355.
422. Walker C & Embleton A. (1906) On the origin of the Sertoli or foot-cells of the testis. Proc Royal Soc London, Series B 78, 50-52.
423. Walker WH. (2003a) Molecular mechanisms controlling Sertoli cell proliferation and differentiation. Endocrinology 144, 3719-3721.
424. Walker WH. (2003b) Nongenomic actions of androgen in Sertoli cells. Curr Top Dev Biol 56, 25-53.
425. Walker WH & Cheng J. (2005) FSH and testosterone signaling in Sertoli cells. Reproduction 130, 15-28.
426. Wang J, Wreford NG, Lan HY, Atkins R & Hedger MP. (1994) Leukocyte populations of the adult rat testis following removal of the Leydig cells by treatment with ethane dimethane sulfonate and subcutaneous testosterone implants. Biol Reprod 51, 551-561.
427. Wang XN, Li ZS, Ren Y, Jiang T, Wang YQ, Chen M, et al. (2013) The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet 9, e1003645.
428. Weber JE, Russell LD, Wong V & Peterson RN. (1983) Three-dimensional reconstruction of a rat stage V Sertoli cell: II. Morphometry of Sertoli-Sertoli and Sertoli-germ-cell relationships. Am J Anat 167, 163-179.
429. Wilson RM & Griswold MD. (1979) Secreted proteins from rat Sertoli cells. Exp Cell Res 123, 127-135.
430. Wong CH & Cheng CY. (2005) The blood-testis barrier: its biology, regulation, and physiological role in spermatogenesis. Curr Top Dev Biol 71, 263-296.
431. Wong CH, Mruk DD, Lee WM & Cheng CY. (2007) Targeted and reversible disruption of the blood-testis barrier by an FSH mutant-occludin peptide conjugate. Faseb J 21, 438-448.
432. Wong EW & Cheng CY. (2009) Polarity proteins and cell-cell interactions in the testis. Int Rev Cell Mol Biol 278, 309-353.
433. Wong EW & Cheng CY. (2011) Impacts of environmental toxicants on male reproductive dysfunction. Trends Pharmacol Sci 32, 290-299.
434. Wong V & Russell LD. (1983) Three-dimensional reconstruction of a rat stage V Sertoli cell: I. Methods, basic configuration, and dimensions. Am J Anat 167, 143-161.
435. Wright WW. (2015) Stage-specific gene expression by Sertoli cells. In: Sertoli Cell Biology(ed. M Griswold ), pp. 273-306. Elsevier Academic Press, Oxford.
436. Wright WW & Luzarraga ML. (1986) Isolation of cyclic protein-2 from rat seminiferous tubule fluid and Sertoli cell culture medium. Biol Reprod 35, 761-772.
437. Wright WW, Parvinen M, Musto NA, Gunsalus GL, Phillips DM, Mather JP & Bardin CW. (1983) Identification of stage-specific proteins synthesized by rat seminiferous tubules. Biol Reprod 29, 257-270.
438. Wright WW, Zabludoff SD, Erickson-Lawrence M & Karzai AW. (1989) Germ cell-Sertoli cell interactions. Studies of cyclic protein-2 in the seminiferous tubule. Ann N Y Acad Sci 564, 173-185.
439. Wrobel KH & Schimmel M. (1989) Morphology of the bovine Sertoli cell during the spermatogenetic cycle. Cell Tissue Res 257, 93-103.
440. Xiao X, Cheng CY & Mruk DD. (2013) Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat. J Endocrinol 216, 73-86.
441. Xiao X, Mruk DD, Wong CK & Cheng CY. (2014a) Germ cell transport across the seminiferous epithelium during spermatogenesis. Physiology (Bethesda) 29, 286-298.
442. Xiao X, Wong EW, Lie PP, Mruk DD, Wong CK & Cheng CY. (2014b) Cytokines, polarity proteins, and endosomal protein trafficking and signaling-the sertoli cell blood-testis barrier system in vitro as a study model. Methods Enzymol 534, 181-194.
443. Xu J, Anuar F, Ali SM, Ng MY, Phua DC & Hunziker W. (2009) Zona occludens-2 is critical for blood-testis barrier integrity and male fertility. Mol Biol Cell 20, 4268-4277.
444. Yan HH, Mruk DD, Lee WM & Cheng CY. (2008) Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells. FASEB J 22, 1945-1959.
445. Yan W. (2015) Gene knockouts that affect Sertoli cell function. In: Sertoli Cell Biology(ed. M Griswold ), pp. 437-469. Elsevier Academic Press, Oxford.
446. Yang Q-E & Oatley JM. (2015) Early postnatal interactions between Sertoli and germ cells. In: Sertoli Cell Biology(ed. M Griswold ), pp. 81-98. Elsevier Academic Press, Oxford.
447. Yang QE, Kim D, Kaucher A, Oatley MJ & Oatley JM. (2013) CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells. J Cell Sci 126, 1009-1020.
448. Yao HH, Ungewitter E, Franco H & Capel B. (2015) Establishment of fetal Sertoli cells and their role in testis morphogenesis. In: Sertoli Cell Biology(ed. M Griswold ), pp. 57-79. Elsevier Academic Press, Oxford.
449. Yeh JR, Zhang X & Nagano MC. (2011) Wnt5a is a cell-extrinsic factor that supports self-renewal of mouse spermatogonial stem cells. J Cell Sci 124, 2357-2366.
450. Yomogida K, Ohtani H, Harigae H, Ito E, Nishimune Y, Engel JD & Yamamoto M. (1994) Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. Development 120, 1759-1766.
451. Young JC, Wakitani S & Loveland KL. (2015) TGF-beta superfamily signaling in testis formation and early male germline development. Semin Cell Dev Biol 45, 94-103.
452. Young JS, Guttman JA, Vaid KS & Vogl AW. (2009) Tubulobulbar complexes are intercellular podosome-like structures that internalize intact intercellular junctions during epithelial remodeling events in the rat testis. Biol Reprod 80, 162-174.
453. Young JS, Takai Y, Kojic KL & Vogl AW. (2012) Internalization of adhesion junction proteins and their association with recycling endosome marker proteins in rat seminiferous epithelium. Reproduction 143, 347-357.
454. Yule TD, Montoya GD, Russell LD, Williams TM & Tung KS. (1988) Autoantigenic germ cells exist outside the blood testis barrier. J Immunol 141, 1161-1167.
455. Zebrun W & Mollenhauer HH. (1960) Electron microscopic observations on mitochondria of rat testes fixed in potassium permanganate. J Biophys Biochem Cytol 7, 311-314.