Sustained expression of insulin by a genetically engineered sertoli cell line after allotransplantation in diabetic BALB/c mice

Biology of Reproduction

Volumn 90, Issue 5, 2014, Pages

  Kaur, Gurvinder ^a   Thompson, Lea Ann ^a   Pasham, Mithun ^a   Tessanne, Kim ^b   Long, Charles R ^b   Dufour, Jannette M ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Cell based gene therapy; Immune privilege; Insulin; Lentivirus; Mouse sertoli cell line; Sertoli cells; Testis; Transplantation

Indexed keywords

GLUCOSE; HUMAN INSULIN; INSULIN; LENTIVIRUS VECTOR; PARAFFIN; PROINSULIN; RNA;

ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ENGINEERING; CELL SURVIVAL; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME LINKED IMMUNOSORBENT ASSAY; FREEZE THAWING; GLUCOSE BLOOD LEVEL; GRAFT RECIPIENT; GRAFT SURVIVAL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INSULIN RELEASE; LIMIT OF DETECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA ISOLATION; SERTOLI CELL; SIMIAN VIRUS 40; STABLE EXPRESSION; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; GENE THERAPY; GENETIC ENGINEERING; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; PROCEDURES; TRANSPLANTATION;

ANIMALS; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; GENETIC ENGINEERING; GENETIC THERAPY; IMMUNOHISTOCHEMISTRY; MALE; MICE, INBRED BALB C; PROINSULIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SERTOLI CELLS;

EID: 84903790511     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.115600     Document Type: Article

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