메뉴 건너뛰기




Volumn 302, Issue 12, 2012, Pages

Compartmentalization and regulation of iron metabolism proteins protect male germ cells from iron overload

Author keywords

Blood testis barrier; Ferritin secretion; Iron regulatory protein 2; Seminiferous tubule; Sertoli cells

Indexed keywords

FERRITIN; FERROPORTIN; HFE PROTEIN; IRON; IRON BINDING PROTEIN; IRON REGULATORY PROTEIN 2; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; TRANSFERRIN; TRANSFERRIN RECEPTOR;

EID: 84862510604     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00007.2012     Document Type: Article
Times cited : (54)

References (52)
  • 1
    • 78650910257 scopus 로고    scopus 로고
    • Redox regulation of human sperm function: From the physiological control of sperm capacitation to the etiology of infertility and DNA damage in the germ line
    • Aitken RJ, Curry BJ. Redox regulation of human sperm function: from the physiological control of sperm capacitation to the etiology of infertility and DNA damage in the germ line. Antioxid Redox Signal 14: 367-381.
    • Antioxid Redox Signal , vol.14 , pp. 367-381
    • Aitken, R.J.1    Curry, B.J.2
  • 3
    • 0021869570 scopus 로고
    • Morphogenesis and fate of the residual body in human spermiogenesis
    • Breucker H, Schafer E, Holstein AF. Morphogenesis and fate of the residual body in human spermiogenesis. Cell Tissue Res 240: 303-309, 1985.
    • (1985) Cell Tissue Res , vol.240 , pp. 303-309
    • Breucker, H.1    Schafer, E.2    Holstein, A.F.3
  • 7
    • 0017146210 scopus 로고
    • The blood-retinal barriers
    • Cunha-Vaz JG. The blood-retinal barriers. Doc Ophthalmol 41: 287-327, 1976.
    • (1976) Doc Ophthalmol , vol.41 , pp. 287-327
    • Cunha-Vaz, J.G.1
  • 10
    • 0014892078 scopus 로고
    • The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium
    • Dym M, Fawcett DW. The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol Re-prod 3: 308-326, 1970.
    • (1970) Biol Re-prod , vol.3 , pp. 308-326
    • Dym, M.1    Fawcett, D.W.2
  • 11
    • 0032881432 scopus 로고    scopus 로고
    • Glycosyl phosphatidylinositol-anchored ceruloplasmin is expressed by rat Sertoli cells and is concentrated in detergent-insoluble membrane fractions
    • Fortna RR, Watson HA, Nyquist SE. Glycosyl phosphatidylinositol-anchored ceruloplasmin is expressed by rat Sertoli cells and is concentrated in detergent-insoluble membrane fractions. Biol Reprod 61: 1042-1049, 1999.
    • (1999) Biol Reprod , vol.61 , pp. 1042-1049
    • Fortna, R.R.1    Watson, H.A.2    Nyquist, S.E.3
  • 12
    • 0028281565 scopus 로고
    • Immunolocalization of albumin and transferrin in germ cells and Sertoli cells during rat gonadal morphogenesis and postnatal development of the testis
    • Gelly JL, Richoux JP, Grignon G. Immunolocalization of albumin and transferrin in germ cells and Sertoli cells during rat gonadal morphogenesis and postnatal development of the testis. Cell Tissue Res 276: 347-351, 1994.
    • (1994) Cell Tissue Res , vol.276 , pp. 347-351
    • Gelly, J.L.1    Richoux, J.P.2    Grignon, G.3
  • 13
    • 10644266803 scopus 로고    scopus 로고
    • Differential expression of divalent metal transporter DMT1 (Slc11a2) in the spermatogenic epithelium of the developing and adult rat testis
    • Griffin KP, Ward DT, Liu W, Stewart G, Morris ID, Smith CP. Differential expression of divalent metal transporter DMT1 (Slc11a2) in the spermatogenic epithelium of the developing and adult rat testis. Am J Physiol Cell Physiol 288: C176-C184, 2005.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Griffin, K.P.1    Ward, D.T.2    Liu, W.3    Stewart, G.4    Morris, I.D.5    Smith, C.P.6
  • 14
    • 7044247550 scopus 로고    scopus 로고
    • Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina
    • Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL. Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. Mol Vis 10: 598-607, 2004.
    • (2004) Mol Vis , vol.10 , pp. 598-607
    • Hahn, P.1    Dentchev, T.2    Qian, Y.3    Rouault, T.4    Harris, Z.L.5    Dunaief, J.L.6
  • 15
    • 77950920343 scopus 로고    scopus 로고
    • Smith CE. Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 4: Intercellular bridges, mitochondria, nuclear envelope, apoptosis, ubiquiti-nation, membrane/voltage-gated channels, methylation/acetylation, and transcription factors
    • Hermo L, Pelletier RM, Cyr DG, Smith CE. Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 4: intercellular bridges, mitochondria, nuclear envelope, apoptosis, ubiquiti-nation, membrane/voltage-gated channels, methylation/acetylation, and transcription factors. Microsc Res Tech 73: 364-408, 2010.
    • (2010) Microsc Res Tech , vol.73 , pp. 364-408
    • Hermo, L.1    Pelletier, R.M.2    Cyr, D.G.3
  • 17
    • 0036788722 scopus 로고    scopus 로고
    • Iron transporter Nramp2/DMT-1 is associated with the membrane of phago-somes in macrophages and Sertoli cells
    • Jabado N, Canonne-Hergaux F, Gruenheid S, Picard V, Gros P. Iron transporter Nramp2/DMT-1 is associated with the membrane of phago-somes in macrophages and Sertoli cells. Blood 100: 2617-2622, 2002.
    • (2002) Blood , vol.100 , pp. 2617-2622
    • Jabado, N.1    Canonne-Hergaux, F.2    Gruenheid, S.3    Picard, V.4    Gros, P.5
  • 18
    • 0036800144 scopus 로고    scopus 로고
    • Strategy and tactics in the evolution of iron acquisition
    • Kaplan J. Strategy and tactics in the evolution of iron acquisition. Semin Hematol 39: 219-226, 2002.
    • (2002) Semin Hematol , vol.39 , pp. 219-226
    • Kaplan, J.1
  • 19
    • 0025615552 scopus 로고
    • Sertoli cells of the testis: Preparation of cell cultures and effects of retinoids
    • Karl AF, Griswold MD. Sertoli cells of the testis: preparation of cell cultures and effects of retinoids. Methods Enzymol 190: 71-75, 1990.
    • (1990) Methods Enzymol , vol.190 , pp. 71-75
    • Karl, A.F.1    Griswold, M.D.2
  • 21
    • 0025338912 scopus 로고
    • Stage-dependent appearance of sulfhydryl oxidase during spermatogenesis in the testis of rat and hamster. An immunohistochemical study
    • Kumari M, Aumuller G, Bergmann M, Meinhardt A, Seitz J. Stage-dependent appearance of sulfhydryl oxidase during spermatogenesis in the testis of rat and hamster. An immunohistochemical study. Histochemistry 94: 365-371, 1990.
    • (1990) Histochemistry , vol.94 , pp. 365-371
    • Kumari, M.1    Aumuller, G.2    Bergmann, M.3    Meinhardt, A.4    Seitz, J.5
  • 23
    • 0030890609 scopus 로고    scopus 로고
    • The Fas system is a key regulator of germ cell apoptosis in the testis
    • Lee J, Richburg JH, Younkin SC, Boekelheide K. The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 138: 2081-2088, 1997.
    • (1997) Endocrinology , vol.138 , pp. 2081-2088
    • Lee, J.1    Richburg, J.H.2    Younkin, S.C.3    Boekelheide, K.4
  • 24
    • 40349103525 scopus 로고    scopus 로고
    • Macrophages function as a ferritin iron source for cultured human erythroid precursors
    • Leimberg MJ, Prus E, Konijn AM, Fibach E. Macrophages function as a ferritin iron source for cultured human erythroid precursors. J Cell Biochem 103: 1211-1218, 2008.
    • (2008) J Cell Biochem , vol.103 , pp. 1211-1218
    • Leimberg, M.J.1    Prus, E.2    Konijn, A.M.3    Fibach, E.4
  • 25
    • 0033168767 scopus 로고    scopus 로고
    • The C282Y mutation causing hereditary hemochromatosis does not produce a null allele
    • Levy JE, Montross LK, Cohen DE, Fleming MD, Andrews NC. The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. Blood 94: 9-11, 1999.
    • (1999) Blood , vol.94 , pp. 9-11
    • Levy, J.E.1    Montross, L.K.2    Cohen, D.E.3    Fleming, M.D.4    Andrews, N.C.5
  • 28
    • 77953655166 scopus 로고    scopus 로고
    • Drosophila mitoferrin is essential for male fertility: Evidence for a role of mitochondrial iron metabolism during spermatogenesis
    • Metzendorf C, Lind MI. Drosophila mitoferrin is essential for male fertility: evidence for a role of mitochondrial iron metabolism during spermatogenesis. BMC Dev Biol 10: 68, 2010.
    • (2010) BMC Dev Biol , vol.10 , pp. 68
    • Metzendorf, C.1    Lind, M.I.2
  • 30
    • 10844282789 scopus 로고    scopus 로고
    • Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo
    • Meyron-Holtz EG, Ghosh MC, Rouault TA. Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo. Science 306: 2087-2090, 2004.
    • (2004) Science , vol.306 , pp. 2087-2090
    • Meyron-Holtz, E.G.1    Ghosh, M.C.2    Rouault, T.A.3
  • 31
    • 79956267665 scopus 로고    scopus 로고
    • The blood-testis and blood-epididymis barriers are more than just their tight junctions
    • Mital P, Hinton BT, Dufour JM. The blood-testis and blood-epididymis barriers are more than just their tight junctions. Biol Reprod 84: 851-858, 2011.
    • (2011) Biol Reprod , vol.84 , pp. 851-858
    • Mital, P.1    Hinton, B.T.2    Dufour, J.M.3
  • 32
    • 0022773522 scopus 로고
    • Receptor-mediated endocytosis of transferrin by Sertoli cells of the rat
    • Morales C, Clermont Y. Receptor-mediated endocytosis of transferrin by Sertoli cells of the rat. Biol Reprod 35: 393-405, 1986.
    • (1986) Biol Reprod , vol.35 , pp. 393-405
    • Morales, C.1    Clermont, Y.2
  • 33
    • 0023441536 scopus 로고
    • Transport of iron and transfer-rin synthesis by the seminiferous epithelium of the rat in vivo
    • Morales C, Sylvester SR, Griswold MD. Transport of iron and transfer-rin synthesis by the seminiferous epithelium of the rat in vivo. Biol Reprod 37: 995-1005, 1987.
    • (1987) Biol Reprod , vol.37 , pp. 995-1005
    • Morales, C.1    Sylvester, S.R.2    Griswold, M.D.3
  • 35
    • 35148886724 scopus 로고    scopus 로고
    • The relevance of the intestinal crypt and enterocyte in regulating iron absorption
    • Oates PS. The relevance of the intestinal crypt and enterocyte in regulating iron absorption. Pflugers Arch 455: 201-213, 2007.
    • (2007) Pflugers Arch , vol.455 , pp. 201-213
    • Oates, P.S.1
  • 36
    • 0026515577 scopus 로고
    • Blood-testis barriers revisited. A homage to Lennart Nicander
    • Plöen L, Setchell BP. Blood-testis barriers revisited. A homage to Lennart Nicander. Int J Androl 15: 1-4, 1992.
    • (1992) Int J Androl , vol.15 , pp. 1-4
    • Plöen, L.1    Setchell, B.P.2
  • 37
    • 34250689012 scopus 로고    scopus 로고
    • Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene
    • Pryce BA, Brent AE, Murchison ND, Tabin CJ, Schweitzer R. Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene. Dev Dyn 236: 1677-1682, 2007.
    • (2007) Dev Dyn , vol.236 , pp. 1677-1682
    • Pryce, B.A.1    Brent, A.E.2    Murchison, N.D.3    Tabin, C.J.4    Schweitzer, R.5
  • 38
    • 0025220364 scopus 로고
    • Characterization of rat transferrin receptor cDNA: The regulation of transferrin receptor mRNA in testes and in Sertoli cells in culture
    • Roberts KP, Griswold MD. Characterization of rat transferrin receptor cDNA: the regulation of transferrin receptor mRNA in testes and in Sertoli cells in culture. Mol Endocrinol 4: 531-542, 1990.
    • (1990) Mol Endocrinol , vol.4 , pp. 531-542
    • Roberts, K.P.1    Griswold, M.D.2
  • 39
    • 0023713448 scopus 로고
    • Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA
    • Rouault TA, Hentze MW, Caughman SW, Harford JB, Klausner RD. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science 241: 1207-1210, 1988.
    • (1988) Science , vol.241 , pp. 1207-1210
    • Rouault, T.A.1    Hentze, M.W.2    Caughman, S.W.3    Harford, J.B.4    Klausner, R.D.5
  • 40
    • 74449085808 scopus 로고    scopus 로고
    • Brain iron homeostasis, the choroids plexus, and localization of iron transport proteins
    • Rouault TA, Zhang DL, Jeong SY. Brain iron homeostasis, the choroids plexus, and localization of iron transport proteins. Metab Brain Dis 24: 673-684, 2009.
    • (2009) Metab Brain Dis , vol.24 , pp. 673-684
    • Rouault, T.A.1    Zhang, D.L.2    Jeong, S.Y.3
  • 45
    • 0020315407 scopus 로고
    • Secretion of testicular transferrin by cultured Sertoli cells is regulated by hormones and retinoids
    • Skinner MK, Griswold MD. Secretion of testicular transferrin by cultured Sertoli cells is regulated by hormones and retinoids. Biol Reprod 27: 211-221, 1982.
    • (1982) Biol Reprod , vol.27 , pp. 211-221
    • Skinner, M.K.1    Griswold, M.D.2
  • 46
    • 0020956334 scopus 로고
    • Sertoli cells synthesize and secrete a ceruloplasmin-like protein
    • Skinner MK, Griswold MD. Sertoli cells synthesize and secrete a ceruloplasmin-like protein. Biol Reprod 28: 1225-1229, 1983.
    • (1983) Biol Reprod , vol.28 , pp. 1225-1229
    • Skinner, M.K.1    Griswold, M.D.2
  • 47
    • 78651299482 scopus 로고    scopus 로고
    • The retinal pigment epithelium in health and disease
    • Sparrow JR, Hicks D, Hamel CP. The retinal pigment epithelium in health and disease. Curr Mol Med 10: 802-823, 2010.
    • (2010) Curr Mol Med , vol.10 , pp. 802-823
    • Sparrow, J.R.1    Hicks, D.2    Hamel, C.P.3
  • 48
    • 0021185936 scopus 로고
    • Localization of transferrin and transferrin receptors in rat testes
    • Sylvester SR, Griswold MD. Localization of transferrin and transferrin receptors in rat testes. Biol Reprod 31: 195-203, 1984.
    • (1984) Biol Reprod , vol.31 , pp. 195-203
    • Sylvester, S.R.1    Griswold, M.D.2
  • 49
    • 0027996689 scopus 로고
    • The testicular iron shuttle: A "nurse" function of the Sertoli cells
    • Sylvester SR, Griswold MD. The testicular iron shuttle: a "nurse" function of the Sertoli cells. J Androl 15: 381-385, 1994.
    • (1994) J Androl , vol.15 , pp. 381-385
    • Sylvester, S.R.1    Griswold, M.D.2
  • 50
    • 0022850982 scopus 로고
    • Transferrin receptors of isolated rat seminiferous tubules bind both rat and human trans-ferrin
    • Wauben-Penris PJ, Strous GJ, Van der Donk HA. Transferrin receptors of isolated rat seminiferous tubules bind both rat and human trans-ferrin. Biol Reprod 35: 1227-1234, 1986.
    • (1986) Biol Reprod , vol.35 , pp. 1227-1234
    • Wauben-Penris, P.J.1    Strous, G.J.2    van der Donk, H.A.3
  • 51
    • 79951919484 scopus 로고    scopus 로고
    • Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking
    • Wolff NA, Liu W, Fenton RA, Lee WK, Thévenod F, Smith CP. Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking. J Cell Mol Med 15: 209-219, 2011.
    • (2011) J Cell Mol Med , vol.15 , pp. 209-219
    • Wolff, N.A.1    Liu, W.2    Fenton, R.A.3    Lee, W.K.4    Thévenod, F.5    Smith, C.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.