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Volumn 150, Issue 2, 2016, Pages 367-379.e1

Relationship between Microbiota of the Colonic Mucosa vs Feces and Symptoms, Colonic Transit, and Methane Production in Female Patients with Chronic Constipation

Author keywords

Irritable Bowel Syndrome; Microbiome

Indexed keywords

DNA; LACTULOSE; METHANE; RNA 16S;

EID: 84959453587     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.10.005     Document Type: Article
Times cited : (305)

References (66)
  • 1
    • 13944255868 scopus 로고    scopus 로고
    • Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR
    • E. Malinen, T. Rinttila, K. Kajander, and et al. Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR Am J Gastroenterol 100 2005 373 382
    • (2005) Am J Gastroenterol , vol.100 , pp. 373-382
    • Malinen, E.1    Rinttila, T.2    Kajander, K.3
  • 2
    • 34447104397 scopus 로고    scopus 로고
    • The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects
    • A. Kassinen, L. Krogius-Kurikka, H. Makivuokko, and et al. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects Gastroenterology 133 2007 24 33
    • (2007) Gastroenterology , vol.133 , pp. 24-33
    • Kassinen, A.1    Krogius-Kurikka, L.2    Makivuokko, H.3
  • 3
    • 74549200558 scopus 로고    scopus 로고
    • Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification
    • A. Lyra, T. Rinttila, J. Nikkila, and et al. Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification World J Gastroenterol 15 2009 5936 5945
    • (2009) World J Gastroenterol , vol.15 , pp. 5936-5945
    • Lyra, A.1    Rinttila, T.2    Nikkila, J.3
  • 4
    • 74549185684 scopus 로고    scopus 로고
    • Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers
    • L. Krogius-Kurikka, A. Lyra, E. Malinen, and et al. Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers BMC Gastroenterol 9 2009 95
    • (2009) BMC Gastroenterol , vol.9 , pp. 95
    • Krogius-Kurikka, L.1    Lyra, A.2    Malinen, E.3
  • 5
    • 77950670562 scopus 로고    scopus 로고
    • Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome
    • C. Tana, Y. Umesaki, A. Imaoka, and et al. Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome Neurogastroenterol Motil 22 2010 512 519
    • (2010) Neurogastroenterol Motil , vol.22 , pp. 512-519
    • Tana, C.1    Umesaki, Y.2    Imaoka, A.3
  • 6
    • 84861185968 scopus 로고    scopus 로고
    • Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome
    • I.M. Carroll, T. Ringel-Kulka, J.P. Siddle, and et al. Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome Neurogastroenterol Motil 24 2012 521 530
    • (2012) Neurogastroenterol Motil , vol.24 , pp. 521-530
    • Carroll, I.M.1    Ringel-Kulka, T.2    Siddle, J.P.3
  • 7
    • 84861578319 scopus 로고    scopus 로고
    • An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota
    • I.B. Jeffery, P.W. O'Toole, L. Ohman, and et al. An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota Gut 61 2012 997 1006
    • (2012) Gut , vol.61 , pp. 997-1006
    • Jeffery, I.B.1    O'Toole, P.W.2    Ohman, L.3
  • 8
    • 84862829772 scopus 로고    scopus 로고
    • Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome
    • C. Chassard, M. Dapoigny, K.P. Scott, and et al. Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome Aliment Pharmacol Ther 35 2012 828 838
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 828-838
    • Chassard, C.1    Dapoigny, M.2    Scott, K.P.3
  • 9
    • 84926189914 scopus 로고    scopus 로고
    • Crosstalk at the mucosal border: Importance of the gut microenvironment in IBS
    • L. Ohman, H. Tornblom, and M. Simren Crosstalk at the mucosal border: importance of the gut microenvironment in IBS Nat Rev Gastroenterol Hepatol 12 2015 36 49
    • (2015) Nat Rev Gastroenterol Hepatol , vol.12 , pp. 36-49
    • Ohman, L.1    Tornblom, H.2    Simren, M.3
  • 10
    • 84871120114 scopus 로고    scopus 로고
    • Intestinal microbiota in functional bowel disorders: A Rome foundation report
    • M. Simren, G. Barbara, H.J. Flint, and et al. Intestinal microbiota in functional bowel disorders: a Rome foundation report Gut 62 2013 159 176
    • (2013) Gut , vol.62 , pp. 159-176
    • Simren, M.1    Barbara, G.2    Flint, H.J.3
  • 11
    • 84929702690 scopus 로고    scopus 로고
    • Gut microbiota: Optimal sampling of the intestinal microbiota for research
    • R.B. Sartor Gut microbiota: optimal sampling of the intestinal microbiota for research Nat Rev Gastroenterol Hepatol 12 2015 253 254
    • (2015) Nat Rev Gastroenterol Hepatol , vol.12 , pp. 253-254
    • Sartor, R.B.1
  • 12
    • 84155180844 scopus 로고    scopus 로고
    • Distinct microbial populations exist in the mucosa-associated microbiota of sub-groups of irritable bowel syndrome
    • G.C. Parkes, N.B. Rayment, B.N. Hudspith, and et al. Distinct microbial populations exist in the mucosa-associated microbiota of sub-groups of irritable bowel syndrome Neurogastroenterol Motil 24 2012 31 39
    • (2012) Neurogastroenterol Motil , vol.24 , pp. 31-39
    • Parkes, G.C.1    Rayment, N.B.2    Hudspith, B.N.3
  • 13
    • 76849116160 scopus 로고    scopus 로고
    • A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome
    • C. Codling, L. O'Mahony, F. Shanahan, and et al. A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome Dig Dis Sci 55 2010 392 397
    • (2010) Dig Dis Sci , vol.55 , pp. 392-397
    • Codling, C.1    O'Mahony, L.2    Shanahan, F.3
  • 14
    • 80051785670 scopus 로고    scopus 로고
    • Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome
    • I.M. Carroll, Y.H. Chang, J. Park, and et al. Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome Gut Pathog 2 2010 19
    • (2010) Gut Pathog , vol.2 , pp. 19
    • Carroll, I.M.1    Chang, Y.H.2    Park, J.3
  • 15
    • 84858604441 scopus 로고    scopus 로고
    • Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome
    • A. Durban, J.J. Abellan, N. Jimenez-Hernandez, and et al. Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome Environ Microbiol Rep 4 2012 242 247
    • (2012) Environ Microbiol Rep , vol.4 , pp. 242-247
    • Durban, A.1    Abellan, J.J.2    Jimenez-Hernandez, N.3
  • 16
    • 80054119513 scopus 로고    scopus 로고
    • Molecular analysis of the luminal- and mucosal-associated intestinal microbiota in diarrhea-predominant irritable bowel syndrome
    • I.M. Carroll, T. Ringel-Kulka, T.O. Keku, and et al. Molecular analysis of the luminal- and mucosal-associated intestinal microbiota in diarrhea-predominant irritable bowel syndrome Am J Physiol Gastrointest Liver Physiol 301 2011 G799 G807
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301 , pp. G799-G807
    • Carroll, I.M.1    Ringel-Kulka, T.2    Keku, T.O.3
  • 17
    • 84876468494 scopus 로고    scopus 로고
    • Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice
    • P.C. Kashyap, A. Marcobal, L.K. Ursell, and et al. Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice Gastroenterology 144 2013 967 977
    • (2013) Gastroenterology , vol.144 , pp. 967-977
    • Kashyap, P.C.1    Marcobal, A.2    Ursell, L.K.3
  • 18
    • 0031715489 scopus 로고    scopus 로고
    • The intestinal ecosystem in chronic functional constipation
    • G. Zoppi, M. Cinquetti, A. Luciano, and et al. The intestinal ecosystem in chronic functional constipation Acta Paediatr 87 1998 836 841
    • (1998) Acta Paediatr , vol.87 , pp. 836-841
    • Zoppi, G.1    Cinquetti, M.2    Luciano, A.3
  • 19
    • 33644878279 scopus 로고    scopus 로고
    • Alterations in the colonic flora and intestinal permeability and evidence of immune activation in chronic constipation
    • I.L. Khalif, E.M. Quigley, E.A. Konovitch, and et al. Alterations in the colonic flora and intestinal permeability and evidence of immune activation in chronic constipation Dig Liver Dis 37 2005 838 849
    • (2005) Dig Liver Dis , vol.37 , pp. 838-849
    • Khalif, I.L.1    Quigley, E.M.2    Konovitch, E.A.3
  • 20
    • 84907149871 scopus 로고    scopus 로고
    • Structural changes in the gut microbiome of constipated patients
    • L. Zhu, W. Liu, R. Alkhouri, and et al. Structural changes in the gut microbiome of constipated patients Physiol Genomics 46 2014 679 686
    • (2014) Physiol Genomics , vol.46 , pp. 679-686
    • Zhu, L.1    Liu, W.2    Alkhouri, R.3
  • 21
    • 84922467857 scopus 로고    scopus 로고
    • Gut microbial and short-chain fatty acid profiles in adults with chronic constipation before and after treatment with lubiprostone
    • D.W. Kang, J.K. DiBaise, Z.E. Ilhan, and et al. Gut microbial and short-chain fatty acid profiles in adults with chronic constipation before and after treatment with lubiprostone Anaerobe 33 2015 33 41
    • (2015) Anaerobe , vol.33 , pp. 33-41
    • Kang, D.W.1    DiBaise, J.K.2    Ilhan, Z.E.3
  • 22
    • 77953230588 scopus 로고    scopus 로고
    • Methanogenic flora is associated with altered colonic transit but not stool characteristics in constipation without IBS
    • A. Attaluri, M. Jackson, J. Valestin, and et al. Methanogenic flora is associated with altered colonic transit but not stool characteristics in constipation without IBS Am J Gastroenterol 105 2010 1407 1411
    • (2010) Am J Gastroenterol , vol.105 , pp. 1407-1411
    • Attaluri, A.1    Jackson, M.2    Valestin, J.3
  • 23
    • 33646866568 scopus 로고    scopus 로고
    • Methane, a gas produced by enteric bacteria, slows intestinal transit and augments small intestinal contractile activity
    • M. Pimentel, H.C. Lin, P. Enayati, and et al. Methane, a gas produced by enteric bacteria, slows intestinal transit and augments small intestinal contractile activity Am J Physiol Gastrointest Liver Physiol 290 2006 G1089 G1095
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. G1089-G1095
    • Pimentel, M.1    Lin, H.C.2    Enayati, P.3
  • 24
    • 79959769742 scopus 로고    scopus 로고
    • Methane on breath testing is associated with constipation: A systematic review and meta-analysis
    • D. Kunkel, R.J. Basseri, M.D. Makhani, and et al. Methane on breath testing is associated with constipation: a systematic review and meta-analysis Dig Dis Sci 56 2011 1612 1618
    • (2011) Dig Dis Sci , vol.56 , pp. 1612-1618
    • Kunkel, D.1    Basseri, R.J.2    Makhani, M.D.3
  • 26
    • 84871330788 scopus 로고    scopus 로고
    • American Gastroenterological Association technical review on constipation
    • A.E. Bharucha, J.H. Pemberton, and G.R. Locke 3rd American Gastroenterological Association technical review on constipation Gastroenterology 144 2013 218 238
    • (2013) Gastroenterology , vol.144 , pp. 218-238
    • Bharucha, A.E.1    Pemberton, J.H.2    Locke, G.R.3
  • 27
    • 84870300737 scopus 로고    scopus 로고
    • Performance characteristics of scintigraphic measurement of gastric emptying of solids in healthy participants
    • 1076-e1562
    • M. Camilleri, J. Iturrino, A.E. Bharucha, and et al. Performance characteristics of scintigraphic measurement of gastric emptying of solids in healthy participants Neurogastroenterol Motil 24 2012 1076-e1562
    • (2012) Neurogastroenterol Motil , vol.24
    • Camilleri, M.1    Iturrino, J.2    Bharucha, A.E.3
  • 28
    • 77949307822 scopus 로고    scopus 로고
    • Performance characteristics of scintigraphic colon transit measurement in health and irritable bowel syndrome and relationship to bowel functions
    • e495
    • A. Deiteren, M. Camilleri, A.E. Bharucha, and et al. Performance characteristics of scintigraphic colon transit measurement in health and irritable bowel syndrome and relationship to bowel functions Neurogastroenterol Motil 22 2010 415 423 e495
    • (2010) Neurogastroenterol Motil , vol.22 , pp. 415-423
    • Deiteren, A.1    Camilleri, M.2    Bharucha, A.E.3
  • 29
    • 70449713952 scopus 로고    scopus 로고
    • The NIH Human Microbiome Project
    • J. Peterson, S. Garges, M. Giovanni, and et al. The NIH Human Microbiome Project Genome Res 19 2009 2317 2323
    • (2009) Genome Res , vol.19 , pp. 2317-2323
    • Peterson, J.1    Garges, S.2    Giovanni, M.3
  • 30
    • 80055082991 scopus 로고    scopus 로고
    • On the suitability of short reads of 16S rRNA for phylogeny-based analyses in environmental surveys
    • P. Jeraldo, N. Chia, and N. Goldenfeld On the suitability of short reads of 16S rRNA for phylogeny-based analyses in environmental surveys Environ Microbiol 13 2011 3000 3009
    • (2011) Environ Microbiol , vol.13 , pp. 3000-3009
    • Jeraldo, P.1    Chia, N.2    Goldenfeld, N.3
  • 31
    • 84918559643 scopus 로고    scopus 로고
    • IM-TORNADO: A tool for comparison of 16S reads from paired-end libraries
    • P. Jeraldo, K. Kalari, X. Chen, and et al. IM-TORNADO: a tool for comparison of 16S reads from paired-end libraries PLoS One 9 2014 e114804
    • (2014) PLoS One , vol.9 , pp. e114804
    • Jeraldo, P.1    Kalari, K.2    Chen, X.3
  • 32
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: A flexible trimmer for Illumina sequence data
    • A.M. Bolger, M. Lohse, and B. Usadel Trimmomatic: a flexible trimmer for Illumina sequence data Bioinformatics 30 2014 2114 2120
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1    Lohse, M.2    Usadel, B.3
  • 33
    • 72949107142 scopus 로고    scopus 로고
    • Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities
    • P.D. Schloss, S.L. Westcott, T. Ryabin, and et al. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities Appl Environ Microbiol 75 2009 7537 7541
    • (2009) Appl Environ Microbiol , vol.75 , pp. 7537-7541
    • Schloss, P.D.1    Westcott, S.L.2    Ryabin, T.3
  • 34
    • 65549111754 scopus 로고    scopus 로고
    • Infernal 1.0: Inference of RNA alignments
    • E.P. Nawrocki, D.L. Kolbe, and S.R. Eddy Infernal 1.0: inference of RNA alignments Bioinformatics 25 2009 1335 1337
    • (2009) Bioinformatics , vol.25 , pp. 1335-1337
    • Nawrocki, E.P.1    Kolbe, D.L.2    Eddy, S.R.3
  • 35
    • 84884904719 scopus 로고    scopus 로고
    • UPARSE: Highly accurate OTU sequences from microbial amplicon reads
    • R.C. Edgar UPARSE: highly accurate OTU sequences from microbial amplicon reads Nat Methods 10 2013 996 998
    • (2013) Nat Methods , vol.10 , pp. 996-998
    • Edgar, R.C.1
  • 36
    • 67649327176 scopus 로고    scopus 로고
    • FastTree: Computing large minimum evolution trees with profiles instead of a distance matrix
    • M.N. Price, P.S. Dehal, and A.P. Arkin FastTree: computing large minimum evolution trees with profiles instead of a distance matrix Mol Biol Evol 26 2009 1641 1650
    • (2009) Mol Biol Evol , vol.26 , pp. 1641-1650
    • Price, M.N.1    Dehal, P.S.2    Arkin, A.P.3
  • 37
    • 33947269742 scopus 로고    scopus 로고
    • Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities
    • C.A. Lozupone, M. Hamady, S.T. Kelley, and et al. Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities Appl Environ Microbiol 73 2007 1576 1585
    • (2007) Appl Environ Microbiol , vol.73 , pp. 1576-1585
    • Lozupone, C.A.1    Hamady, M.2    Kelley, S.T.3
  • 38
    • 0035478854 scopus 로고    scopus 로고
    • Random forests
    • L. Breiman Random forests Mach Learn 45 2001 5 32
    • (2001) Mach Learn , vol.45 , pp. 5-32
    • Breiman, L.1
  • 39
  • 40
    • 84943611526 scopus 로고    scopus 로고
    • Power and sample-size estimation for microbiome studies using pairwise distances and PERMANOVA
    • B.J. Kelly, R. Gross, K. Bittinger, and et al. Power and sample-size estimation for microbiome studies using pairwise distances and PERMANOVA Bioinformatics 31 2015 2461 2468
    • (2015) Bioinformatics , vol.31 , pp. 2461-2468
    • Kelly, B.J.1    Gross, R.2    Bittinger, K.3
  • 41
    • 80054851581 scopus 로고    scopus 로고
    • Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome
    • D.M. Saulnier, K. Riehle, T.A. Mistretta, and et al. Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome Gastroenterology 141 2011 1782 1791
    • (2011) Gastroenterology , vol.141 , pp. 1782-1791
    • Saulnier, D.M.1    Riehle, K.2    Mistretta, T.A.3
  • 42
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • G.D. Wu, J. Chen, C. Hoffmann, and et al. Linking long-term dietary patterns with gut microbial enterotypes Science 334 2011 105 108
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1    Chen, J.2    Hoffmann, C.3
  • 43
    • 84863871551 scopus 로고    scopus 로고
    • Microbial degradation of complex carbohydrates in the gut
    • H.J. Flint, K.P. Scott, S.H. Duncan, and et al. Microbial degradation of complex carbohydrates in the gut Gut Microbes 3 2012 289 306
    • (2012) Gut Microbes , vol.3 , pp. 289-306
    • Flint, H.J.1    Scott, K.P.2    Duncan, S.H.3
  • 44
    • 0034023665 scopus 로고    scopus 로고
    • Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colon
    • A. Barcelo, J. Claustre, F. Moro, and et al. Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colon Gut 46 2000 218 224
    • (2000) Gut , vol.46 , pp. 218-224
    • Barcelo, A.1    Claustre, J.2    Moro, F.3
  • 45
    • 0024562962 scopus 로고
    • Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon
    • H.J. Binder, and P. Mehta Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon Gastroenterology 96 1989 989 996
    • (1989) Gastroenterology , vol.96 , pp. 989-996
    • Binder, H.J.1    Mehta, P.2
  • 46
    • 79960191804 scopus 로고    scopus 로고
    • The function of lactic acid bacteria and brine solutions on biogenic amine formation by foodborne pathogens in trout fillets
    • E. Kuley, F. Ozogul, Y. Ozogul, and et al. The function of lactic acid bacteria and brine solutions on biogenic amine formation by foodborne pathogens in trout fillets Food Chem 129 2011 1211 1216
    • (2011) Food Chem , vol.129 , pp. 1211-1216
    • Kuley, E.1    Ozogul, F.2    Ozogul, Y.3
  • 47
    • 84905235179 scopus 로고    scopus 로고
    • Minireview: Gut microbiota: The neglected endocrine organ
    • G. Clarke, R.M. Stilling, P.J. Kennedy, and et al. Minireview: gut microbiota: the neglected endocrine organ Mol Endocrinol 28 2014 1221 1238
    • (2014) Mol Endocrinol , vol.28 , pp. 1221-1238
    • Clarke, G.1    Stilling, R.M.2    Kennedy, P.J.3
  • 48
    • 80054857288 scopus 로고    scopus 로고
    • Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    • M. Rajilic-Stojanovic, E. Biagi, H.G. Heilig, and et al. Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome Gastroenterology 141 2011 1792 1801
    • (2011) Gastroenterology , vol.141 , pp. 1792-1801
    • Rajilic-Stojanovic, M.1    Biagi, E.2    Heilig, H.G.3
  • 49
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • R.E. Ley, P.J. Turnbaugh, S. Klein, and et al. Microbial ecology: human gut microbes associated with obesity Nature 444 2006 1022 1023
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3
  • 50
    • 84897138661 scopus 로고    scopus 로고
    • A taxonomic signature of obesity in the microbiome? Getting to the guts of the matter
    • M.M. Finucane, T.J. Sharpton, T.J. Laurent, and et al. A taxonomic signature of obesity in the microbiome? Getting to the guts of the matter PLoS One 9 2014 e84689
    • (2014) PLoS One , vol.9 , pp. e84689
    • Finucane, M.M.1    Sharpton, T.J.2    Laurent, T.J.3
  • 51
    • 4544323598 scopus 로고    scopus 로고
    • Obesity is associated with increased risk of gastrointestinal symptoms: A population-based study
    • S. Delgado-Aros, G.R. Locke, M. Camilleri, and et al. Obesity is associated with increased risk of gastrointestinal symptoms: a population-based study Am J Gastroenterol 99 2004 1801 1806
    • (2004) Am J Gastroenterol , vol.99 , pp. 1801-1806
    • Delgado-Aros, S.1    Locke, G.R.2    Camilleri, M.3
  • 53
    • 80054862011 scopus 로고    scopus 로고
    • Bile acid is a host factor that regulates the composition of the cecal microbiota in rats
    • K.B.M.S. Islam, F. Satoru, H. Masahito, and et al. Bile acid is a host factor that regulates the composition of the cecal microbiota in rats Gastroenterology 141 2011 1773 1781
    • (2011) Gastroenterology , vol.141 , pp. 1773-1781
    • Islam, K.B.M.S.1    Satoru, F.2    Masahito, H.3
  • 54
    • 2342604426 scopus 로고    scopus 로고
    • Accelerated regional bowel transit and overweight shown in idiopathic bile acid malabsorption
    • R. Sadik, H. Abrahamsson, K.-A.A. Ung, and et al. Accelerated regional bowel transit and overweight shown in idiopathic bile acid malabsorption Am J Gastroenterol 99 2004 711 718
    • (2004) Am J Gastroenterol , vol.99 , pp. 711-718
    • Sadik, R.1    Abrahamsson, H.2    Ung, K.-A.A.3
  • 55
    • 63849241608 scopus 로고    scopus 로고
    • Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine
    • P. Louis, and H.J. Flint Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine FEMS Microbiol Lett 294 2009 1 8
    • (2009) FEMS Microbiol Lett , vol.294 , pp. 1-8
    • Louis, P.1    Flint, H.J.2
  • 56
    • 84937394501 scopus 로고    scopus 로고
    • Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells
    • C.S. Reigstad, C.E. Salmonson, J.F. Rainey 3rd, and et al. Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells FASEB J 29 2015 1395 1403
    • (2015) FASEB J , vol.29 , pp. 1395-1403
    • Reigstad, C.S.1    Salmonson, C.E.2    Rainey, J.F.3
  • 57
    • 77951684976 scopus 로고    scopus 로고
    • Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats
    • R. Soret, J. Chevalier, P. De Coppet, and et al. Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats Gastroenterology 138 2010 1772 1782
    • (2010) Gastroenterology , vol.138 , pp. 1772-1782
    • Soret, R.1    Chevalier, J.2    De Coppet, P.3
  • 58
    • 0033151756 scopus 로고    scopus 로고
    • Characteristics of mucosally projecting myenteric neurones in the Guinea-pig proximal colon
    • M. Neunlist, G. Dobreva, and M. Schemann Characteristics of mucosally projecting myenteric neurones in the guinea-pig proximal colon J Physiol 517 1999 533 546
    • (1999) J Physiol , vol.517 , pp. 533-546
    • Neunlist, M.1    Dobreva, G.2    Schemann, M.3
  • 59
    • 0026778486 scopus 로고
    • Effect of short-chain fatty acids on contractile activity and fluid flow in rat colon in vitro
    • P.E. Squires, R.D. Rumsey, C.A. Edwards, and et al. Effect of short-chain fatty acids on contractile activity and fluid flow in rat colon in vitro Am J Physiol 262 1992 G813 G817
    • (1992) Am J Physiol , vol.262 , pp. G813-G817
    • Squires, P.E.1    Rumsey, R.D.2    Edwards, C.A.3
  • 60
    • 0025282444 scopus 로고
    • Alternative pathways for hydrogen disposal during fermentation in the human colon
    • G.R. Gibson, J.H. Cummings, G.T. Macfarlane, and et al. Alternative pathways for hydrogen disposal during fermentation in the human colon Gut 31 1990 679 683
    • (1990) Gut , vol.31 , pp. 679-683
    • Gibson, G.R.1    Cummings, J.H.2    Macfarlane, G.T.3
  • 61
    • 84930755064 scopus 로고    scopus 로고
    • Breath methane excretion is not an accurate marker of colonic methane production in irritable bowel syndrome
    • M. Di Stefano, C. Mengoli, M. Bergonzi, and et al. Breath methane excretion is not an accurate marker of colonic methane production in irritable bowel syndrome Am J Gastroenterol 110 2015 891 898
    • (2015) Am J Gastroenterol , vol.110 , pp. 891-898
    • Di Stefano, M.1    Mengoli, C.2    Bergonzi, M.3
  • 62
    • 84919768380 scopus 로고    scopus 로고
    • Diets that differ in their FODMAP content alter the colonic luminal microenvironment
    • E.P. Halmos, C.T. Christophersen, A.R. Bird, and et al. Diets that differ in their FODMAP content alter the colonic luminal microenvironment Gut 64 2015 93 100
    • (2015) Gut , vol.64 , pp. 93-100
    • Halmos, E.P.1    Christophersen, C.T.2    Bird, A.R.3
  • 63
    • 84884418594 scopus 로고    scopus 로고
    • Rome III functional constipation and irritable bowel syndrome with constipation are similar disorders within a spectrum of sensitization, regulated by serotonin
    • quiz e713-e744
    • C. Shekhar, P.J. Monaghan, J. Morris, and et al. Rome III functional constipation and irritable bowel syndrome with constipation are similar disorders within a spectrum of sensitization, regulated by serotonin Gastroenterology 145 2013 749 757 quiz e713-e744
    • (2013) Gastroenterology , vol.145 , pp. 749-757
    • Shekhar, C.1    Monaghan, P.J.2    Morris, J.3
  • 64
    • 77957826668 scopus 로고    scopus 로고
    • Inability of the Rome III criteria to distinguish functional constipation from constipation-subtype irritable bowel syndrome
    • R.K. Wong, O.S. Palsson, M.J. Turner, and et al. Inability of the Rome III criteria to distinguish functional constipation from constipation-subtype irritable bowel syndrome Am J Gastroenterol 105 2010 2228 2234
    • (2010) Am J Gastroenterol , vol.105 , pp. 2228-2234
    • Wong, R.K.1    Palsson, O.S.2    Turner, M.J.3
  • 65
    • 18944401261 scopus 로고    scopus 로고
    • Biodiversity of the mucosa-associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD
    • P. Lepage, P. Seksik, M. Sutren, and et al. Biodiversity of the mucosa-associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD Inflamm Bowel Dis 11 2005 473 480
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 473-480
    • Lepage, P.1    Seksik, P.2    Sutren, M.3
  • 66
    • 84941270425 scopus 로고    scopus 로고
    • Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers
    • A. Lavelle, G. Lennon, O. O'Sullivan, and et al. Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers Gut 64 2015 1553 1561
    • (2015) Gut , vol.64 , pp. 1553-1561
    • Lavelle, A.1    Lennon, G.2    O'Sullivan, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.