메뉴 건너뛰기




Volumn 34, Issue 4, 2016, Pages 860-872

A Role for RE-1-Silencing Transcription Factor in Embryonic Stem Cells Cardiac Lineage Specification

Author keywords

Cardiac lineage; Embryonic stem cells; Endoderm; GATA4; REST; Wnt signaling

Indexed keywords

BETA CATENIN; REPRESSOR ELEMENT 1 SILENCING TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG; WNT PROTEIN; GATA4 PROTEIN, MOUSE; RE1-SILENCING TRANSCRIPTION FACTOR; REPRESSOR PROTEIN;

EID: 84959441573     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2304     Document Type: Article
Times cited : (5)

References (53)
  • 1
    • 33846936237 scopus 로고    scopus 로고
    • RE1 Silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells
    • Greenway DJ, Street M, Jeffries A, et al., RE1 Silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells. Stem Cells 2007; 25: 354-363.
    • (2007) Stem Cells , vol.25 , pp. 354-363
    • Greenway, D.J.1    Street, M.2    Jeffries, A.3
  • 2
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas N, Grunseich C, Lu DD, et al., REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 2005; 121: 645-657.
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3
  • 3
    • 65549095495 scopus 로고    scopus 로고
    • REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells
    • Jørgensen HF, Terry A, Beretta C, et al., REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells. Development 2009; 136: 715-721.
    • (2009) Development , vol.136 , pp. 715-721
    • Jørgensen, H.F.1    Terry, A.2    Beretta, C.3
  • 4
    • 0031694917 scopus 로고    scopus 로고
    • NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
    • Chen ZF, Paquette AJ, Anderson DJ,. NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nat Genet 1998; 20: 136-142.
    • (1998) Nat Genet , vol.20 , pp. 136-142
    • Chen, Z.F.1    Paquette, A.J.2    Anderson, D.J.3
  • 5
    • 25844518743 scopus 로고    scopus 로고
    • The many faces of REST oversee epigenetic programming of neuronal genes
    • Ballas N, Mandel G,. The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol 2005; 15: 500-506.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 500-506
    • Ballas, N.1    Mandel, G.2
  • 6
    • 0028934541 scopus 로고
    • REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
    • Chong JA, Tapia-Ramírez J, Kim S, et al., REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 1995; 80: 949-957.
    • (1995) Cell , vol.80 , pp. 949-957
    • Chong, J.A.1    Tapia-Ramírez, J.2    Kim, S.3
  • 7
    • 0028968802 scopus 로고
    • The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
    • Schoenherr CJ, Anderson DJ,. The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes. Science 1995; 267: 1360-1363.
    • (1995) Science , vol.267 , pp. 1360-1363
    • Schoenherr, C.J.1    Anderson, D.J.2
  • 8
    • 3142764484 scopus 로고    scopus 로고
    • Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes
    • Bruce AW, Donaldson IJ, Wood IC, et al., Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci USA 2004; 101: 10458-10463.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10458-10463
    • Bruce, A.W.1    Donaldson, I.J.2    Wood, I.C.3
  • 9
    • 24044505984 scopus 로고    scopus 로고
    • Transcriptional regulation: Cancer, neurons and the REST
    • Coulson JM,. Transcriptional regulation: Cancer, neurons and the REST. Curr Biol 2005; 15: R663-R665.
    • (2005) Curr Biol , vol.15 , pp. R663-R665
    • Coulson, J.M.1
  • 10
    • 19344372003 scopus 로고    scopus 로고
    • No Rest for REST: REST/NRSF regulation of neurogenesis
    • Lunyak VV, Rosenfel MG,. No Rest for REST: REST/NRSF regulation of neurogenesis. Cell 2005; 121: 497-499.
    • (2005) Cell , vol.121 , pp. 497-499
    • Lunyak, V.V.1    Rosenfel, M.G.2
  • 11
    • 27544454705 scopus 로고    scopus 로고
    • Chromatin remodeling in neural development and plasticity
    • Hsieh J, Gage FH,. Chromatin remodeling in neural development and plasticity. Curr Opin Cell biol 2005; 17: 664-671.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 664-671
    • Hsieh, J.1    Gage, F.H.2
  • 12
    • 33745602880 scopus 로고    scopus 로고
    • Noncoding RNAs in the mammalian central nervous system
    • Cao X, Yeo G, Muotri AR, et al., Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci 2006; 29: 77-103.
    • (2006) Annu Rev Neurosci , vol.29 , pp. 77-103
    • Cao, X.1    Yeo, G.2    Muotri, A.R.3
  • 13
    • 20444376939 scopus 로고    scopus 로고
    • A genetic screen for candidate tumor suppressors identifies REST
    • Westbrook TF, Martin ES, Schlabach MR, et al., A genetic screen for candidate tumor suppressors identifies REST. Cell 2005; 121: 837-848.
    • (2005) Cell , vol.121 , pp. 837-848
    • Westbrook, T.F.1    Martin, E.S.2    Schlabach, M.R.3
  • 14
    • 15944374306 scopus 로고    scopus 로고
    • Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16
    • Fuller GN, Su X, Price RE, et al., Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16. Mol Cancer Ther 2005; 4: 343-350.
    • (2005) Mol Cancer Ther , vol.4 , pp. 343-350
    • Fuller, G.N.1    Su, X.2    Price, R.E.3
  • 15
    • 84886501227 scopus 로고    scopus 로고
    • Role of NRSF/REST in the regulation of cardiac gene expression and function
    • Kuwahara K,. Role of NRSF/REST in the regulation of cardiac gene expression and function. Circ J 2013; 77: 2682-2686.
    • (2013) Circ J , vol.77 , pp. 2682-2686
    • Kuwahara, K.1
  • 16
    • 33845629427 scopus 로고    scopus 로고
    • NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes
    • Kuratomi S, Kuratomi A, Kuwahara K, et al., NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes. Biochem Biophys Res Commun 2007; 353: 67-73.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 67-73
    • Kuratomi, S.1    Kuratomi, A.2    Kuwahara, K.3
  • 17
    • 10744228125 scopus 로고    scopus 로고
    • NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function
    • Kuwahara K, Saito Y, Takano M, et al., NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. Embo J 2003; 22: 6310-6321.
    • (2003) Embo J , vol.22 , pp. 6310-6321
    • Kuwahara, K.1    Saito, Y.2    Takano, M.3
  • 18
    • 34250749895 scopus 로고    scopus 로고
    • The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes
    • Bingham AJ, Ooi L, Kozera L, et al., The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes. Mol Cell Biol 2007; 27: 4082-4092.
    • (2007) Mol Cell Biol , vol.27 , pp. 4082-4092
    • Bingham, A.J.1    Ooi, L.2    Kozera, L.3
  • 19
    • 33746773659 scopus 로고    scopus 로고
    • Dissecting self-renewal in stem cells with RNA interference
    • Ivanova N, Dobrin R, Lu R, et al., Dissecting self-renewal in stem cells with RNA interference. Nature 2006; 442: 533-538.
    • (2006) Nature , vol.442 , pp. 533-538
    • Ivanova, N.1    Dobrin, R.2    Lu, R.3
  • 20
    • 64349096829 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
    • Hu G, Kim J, Xu Q, et al., A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal. Genes Dev 2009; 23: 837-848.
    • (2009) Genes Dev , vol.23 , pp. 837-848
    • Hu, G.1    Kim, J.2    Xu, Q.3
  • 21
    • 28644440340 scopus 로고    scopus 로고
    • Genes at different stages of neuronal development
    • Sun Y, Greenway DJ, Johnson R, et al., Genes at different stages of neuronal development. Mol Biol Cell 2005; 16: 5630-5638.
    • (2005) Mol Biol Cell , vol.16 , pp. 5630-5638
    • Sun, Y.1    Greenway, D.J.2    Johnson, R.3
  • 22
    • 54949103985 scopus 로고    scopus 로고
    • REST regulates distinct transcriptional networks in embryonic and neural stem cells
    • Johnson R, Teh CH, Kunarso G, et al., REST regulates distinct transcriptional networks in embryonic and neural stem cells. Plos Biol 2008; 6: e256.
    • (2008) Plos Biol , vol.6 , pp. e256
    • Johnson, R.1    Teh, C.H.2    Kunarso, G.3
  • 23
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, et al., Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005; 122: 947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 24
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh Y-H, Wu Q, Chew J-L, et al., The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006; 38: 431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.-H.1    Wu, Q.2    Chew, J.-L.3
  • 25
    • 0029899691 scopus 로고    scopus 로고
    • Differentiation of beating cardiac muscle cells from a derivative of P19 embryonal carcinoma cells
    • Habara-Ohkubo A,. Differentiation of beating cardiac muscle cells from a derivative of P19 embryonal carcinoma cells. Cell struct Funct 1996; 21: 101-110.
    • (1996) Cell Struct Funct , vol.21 , pp. 101-110
    • Habara-Ohkubo, A.1
  • 26
    • 80051571400 scopus 로고    scopus 로고
    • Coassembly of REST and its cofactors at sites of gene repression in embryonic stem cells
    • Yu H-B, Johnson R, Kunarso G, et al., Coassembly of REST and its cofactors at sites of gene repression in embryonic stem cells. Genome Res 2011; 21: 1284-1293.
    • (2011) Genome Res , vol.21 , pp. 1284-1293
    • Yu, H.-B.1    Johnson, R.2    Kunarso, G.3
  • 27
    • 84857496280 scopus 로고    scopus 로고
    • Repressor element 1 silencing transcription factor couples loss of pluripotency with neural induction and neural differentiation
    • Soldati C, Bithell A, Johnston C, et al., Repressor element 1 silencing transcription factor couples loss of pluripotency with neural induction and neural differentiation. Stem Cells 2012; 30: 425-434.
    • (2012) Stem Cells , vol.30 , pp. 425-434
    • Soldati, C.1    Bithell, A.2    Johnston, C.3
  • 28
    • 61349137510 scopus 로고    scopus 로고
    • Is REST a regulator of pluripotency?
    • discussion E7
    • Buckley NJ, Johnson R, Sun Y-M, et al., Is REST a regulator of pluripotency? Nature 2009; 457: E5-6; discussion E7.
    • (2009) Nature , vol.457 , pp. E5-E6
    • Buckley, N.J.1    Johnson, R.2    Sun, Y.-M.3
  • 29
    • 73349091835 scopus 로고    scopus 로고
    • Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance
    • Yamada Y, Aoki H, Kunisada T, et al., Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell Stem Cell 2010; 6: 10-5.
    • (2010) Cell Stem Cell , vol.6 , pp. 10-15
    • Yamada, Y.1    Aoki, H.2    Kunisada, T.3
  • 30
    • 61349200079 scopus 로고    scopus 로고
    • Is REST required for ESC pluripotency?
    • discussion E7
    • Jørgensen HF, Chen ZF, Merkenschlager M, et al., Is REST required for ESC pluripotency? Nature 2009; 457: E4-E5; discussion E7.
    • (2009) Nature , vol.457 , pp. E4-E5
    • Jørgensen, H.F.1    Chen, Z.F.2    Merkenschlager, M.3
  • 31
    • 0033665287 scopus 로고    scopus 로고
    • Gene manipulation and integrative physiology embryoid bodies: An in vitro model of mouse embryogenesis
    • Desbaillets I, Ziegler U, Groscurth P, et al., Gene manipulation and integrative physiology embryoid bodies: An in vitro model of mouse embryogenesis. Exp Phyisol 2000; 85: 645-651.
    • (2000) Exp Phyisol , vol.85 , pp. 645-651
    • Desbaillets, I.1    Ziegler, U.2    Groscurth, P.3
  • 32
    • 0038030960 scopus 로고    scopus 로고
    • Cardiac specific differentiation of mouse embryonic stem cells
    • Sachinidis A, Fleischmann BK, Kolossov E, et al., Cardiac specific differentiation of mouse embryonic stem cells. Cardiovasc Res 2003; 58: 278-291.
    • (2003) Cardiovasc Res , vol.58 , pp. 278-291
    • Sachinidis, A.1    Fleischmann, B.K.2    Kolossov, E.3
  • 33
    • 28644442419 scopus 로고    scopus 로고
    • Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells
    • Yasunaga M, Tada S, Torikai-Nishikawa S, et al., Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol 2005; 23: 1542-1550.
    • (2005) Nat Biotechnol , vol.23 , pp. 1542-1550
    • Yasunaga, M.1    Tada, S.2    Torikai-Nishikawa, S.3
  • 34
    • 70349850452 scopus 로고    scopus 로고
    • Visceral endoderm induces specification of cardiomyocytes in mice
    • Nijmeijer RM, Leeuwis JW, DeLisio A, et al., Visceral endoderm induces specification of cardiomyocytes in mice. Stem Cell Res 2009; 3: 170-178.
    • (2009) Stem Cell Res , vol.3 , pp. 170-178
    • Nijmeijer, R.M.1    Leeuwis, J.W.2    DeLisio, A.3
  • 35
    • 1342280613 scopus 로고    scopus 로고
    • A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells
    • Moore JC, Spijker R, Martens AC, et al., A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells. Int J Dev Biol 2004; 48: 47-55.
    • (2004) Int J Dev Biol , vol.48 , pp. 47-55
    • Moore, J.C.1    Spijker, R.2    Martens, A.C.3
  • 36
    • 0020045043 scopus 로고
    • Isolation of male embryonal carcinoma cells and their chromosome replication patterns
    • McBurney MW, Rogers BJ,. Isolation of male embryonal carcinoma cells and their chromosome replication patterns. Dev Biol 1982; 89: 503-508.
    • (1982) Dev Biol , vol.89 , pp. 503-508
    • McBurney, M.W.1    Rogers, B.J.2
  • 37
    • 61349137510 scopus 로고    scopus 로고
    • Is REST a regulator of pluripotency?
    • discussion E7
    • Buckley NJ, Johnson R, Sun Y-M, et al., Is REST a regulator of pluripotency? Nature 2009; 457: E5-E6; discussion E7.
    • (2009) Nature , vol.457 , pp. E5-E6
    • Buckley, N.J.1    Johnson, R.2    Sun, Y.-M.3
  • 38
    • 0035252357 scopus 로고    scopus 로고
    • Inhibition of Wnt activity induces heart formation from posterior mesoderm
    • Marvin MJ, Di Rocco G, Gardiner A, et al., Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev 2001; 15: 316-327.
    • (2001) Genes Dev , vol.15 , pp. 316-327
    • Marvin, M.J.1    Di Rocco, G.2    Gardiner, A.3
  • 39
    • 33747053437 scopus 로고    scopus 로고
    • Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development
    • Manisastry SM, Han M, Linask KK,. Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development. Dev Dyn 2006; 235: 2160-2174.
    • (2006) Dev Dyn , vol.235 , pp. 2160-2174
    • Manisastry, S.M.1    Han, M.2    Linask, K.K.3
  • 40
    • 0035252543 scopus 로고    scopus 로고
    • Wnt antagonism initiates cardiogenesis in Xenopus laevis
    • Schneider V a, Mercola M,. Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev 2001; 15: 304-315.
    • (2001) Genes Dev , vol.15 , pp. 304-315
    • Schneider, V.A.1    Mercola, M.2
  • 41
    • 24644459320 scopus 로고    scopus 로고
    • Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction
    • Yamashita JK, Takano M, Hiraoka-Kanie M, et al., Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction. Faseb J 2005; 19: 1534-1536.
    • (2005) Faseb J , vol.19 , pp. 1534-1536
    • Yamashita, J.K.1    Takano, M.2    Hiraoka-Kanie, M.3
  • 42
    • 33845928762 scopus 로고    scopus 로고
    • Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
    • Naito AT, Shiojima I, Akazawa H, et al., Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci USA 2006; 103: 19812-19817.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19812-19817
    • Naito, A.T.1    Shiojima, I.2    Akazawa, H.3
  • 43
    • 34250802982 scopus 로고    scopus 로고
    • Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
    • Ueno S, Weidinger G, Osugi T, et al., Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc Natl Acad Sci USA 2007; 104: 9685-9690.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9685-9690
    • Ueno, S.1    Weidinger, G.2    Osugi, T.3
  • 44
    • 0036696415 scopus 로고    scopus 로고
    • Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm
    • Lickert H, Kutsch S, Kanzler B, et al., Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. Dev Cell 2002; 3: 171-181.
    • (2002) Dev Cell , vol.3 , pp. 171-181
    • Lickert, H.1    Kutsch, S.2    Kanzler, B.3
  • 45
    • 80051796581 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm
    • Willems E, Spiering S, Davidovics H, et al., Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. Circ Res 2011; 109: 360-364.
    • (2011) Circ Res , vol.109 , pp. 360-364
    • Willems, E.1    Spiering, S.2    Davidovics, H.3
  • 46
    • 70450224857 scopus 로고    scopus 로고
    • Gata4 directs development of cardiac-inducing endoderm from ES cells
    • Holtzinger A, Rosenfeld GE, Evans T,. Gata4 directs development of cardiac-inducing endoderm from ES cells. Dev Biol 2010; 337: 63-73.
    • (2010) Dev Biol , vol.337 , pp. 63-73
    • Holtzinger, A.1    Rosenfeld, G.E.2    Evans, T.3
  • 47
    • 84873300214 scopus 로고    scopus 로고
    • Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
    • Klattenhoff CA, Scheuermann JC, Surface LE, et al., Braveheart, a long noncoding RNA required for cardiovascular lineage commitment. Cell 2013; 152: 570-583.
    • (2013) Cell , vol.152 , pp. 570-583
    • Klattenhoff, C.A.1    Scheuermann, J.C.2    Surface, L.E.3
  • 49
    • 0034111134 scopus 로고    scopus 로고
    • Endoderm and heart development
    • Lough J, Sugi Y,. Endoderm and heart development. Dev Dyn 2000; 342: 327-342.
    • (2000) Dev Dyn , vol.342 , pp. 327-342
    • Lough, J.1    Sugi, Y.2
  • 50
    • 77955155919 scopus 로고    scopus 로고
    • The multiple phases and faces of wnt signaling during cardiac differentiation and development
    • Gessert S, Kühl M,. The multiple phases and faces of wnt signaling during cardiac differentiation and development. Circ Res 2010; 107: 186-199.
    • (2010) Circ Res , vol.107 , pp. 186-199
    • Gessert, S.1    Kühl, M.2
  • 51
    • 54849407610 scopus 로고    scopus 로고
    • GATA transcription factors integrate Wnt signalling during heart development
    • Afouda BA, Martin J, Liu F, et al., GATA transcription factors integrate Wnt signalling during heart development. Development 2008; 135: 3185-3190.
    • (2008) Development , vol.135 , pp. 3185-3190
    • Afouda, B.A.1    Martin, J.2    Liu, F.3
  • 52
    • 73149101467 scopus 로고    scopus 로고
    • Wnt/beta-catenin signalling regulates cardiomyogenesis via GATA transcription factors
    • Martin J, Afouda BA, Hoppler S,. Wnt/beta-catenin signalling regulates cardiomyogenesis via GATA transcription factors. J Anat 2010; 216: 92-107.
    • (2010) J Anat , vol.216 , pp. 92-107
    • Martin, J.1    Afouda, B.A.2    Hoppler, S.3
  • 53
    • 1642603947 scopus 로고    scopus 로고
    • A small modulatory dsRNA specifies the fate of adult neural stem cells
    • Kuwabara T, Hsieh J, Nakashima K, et al., A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 2004; 116: 779-793.
    • (2004) Cell , vol.116 , pp. 779-793
    • Kuwabara, T.1    Hsieh, J.2    Nakashima, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.