Wnt/β-catenin signalling regulates cardiomyogenesis via GATA transcription factors

Journal of Anatomy

Volumn 216, Issue 1, 2010, Pages 92-107

  Martin, Jennifer ^a   Afouda, Boni A ^a   Hoppler, Stefan ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Cardiogenesis; Cardiomyocytes; GATA; Heart; Muscle; Nkx; Wnt signalling

Indexed keywords

BETA CATENIN; DEXAMETHASONE; MYOSIN; MYOSIN LIGHT CHAIN 2; TRANSCRIPTION FACTOR GATA; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX2.5; TROPONIN; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; HEART DEVELOPMENT; HEART FUNCTION; MESODERM; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TISSUE CULTURE; XENOPUS;

ANIMALS; BETA CATENIN; GATA TRANSCRIPTION FACTORS; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; MODELS, ANIMAL; MYOCARDIUM; ORGANOGENESIS; SIGNAL TRANSDUCTION; WNT PROTEINS; XENOPUS; XENOPUS PROTEINS;

VERTEBRATA;

EID: 73149101467     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2009.01171.x     Document Type: Article

References (37)

1. Afouda BA, Ciau-Uitz A, Patient R. GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos. Development 2005, 132:763-774.
2. Afouda BA, Martin J, Liu F. GATA transcription factors integrate Wnt signalling during heart development. Development 2008, 135:3185-3190.
3. Ariizumi T, Kinoshita M, Yokota C. Amphibian in vitro heart induction: a simple and reliable model for the study of vertebrate cardiac development. Int J Dev Biol 2003, 47:405-410.
4. Brewer A, Pizzey J. GATA factors in vertebrate heart development and disease. Expert Rev Mol Med 2006, 8:1-20.
5. Brewer A, Gove C, Davies A. The human and mouse GATA-6 genes utilize two promoters and two initiation codons. J Biol Chem 1999, 274:38004-38016.
6. Brewer AC, Alexandrovich A, Mjaatvedt CH. GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis. Stem Cells Dev 2005, 14:425-439.
7. Chambers AE, Logan M, Kotecha S. The RSRF/MEF2 protein SL1 regulates cardiac muscle-specific transcription of a myosin light-chain gene in Xenopus embryos. Genes Dev 1994, 8:1324-1334.
8. Cohen ED, Tian Y, Morrisey EE. Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development 2008, 135:789-798.
9. Drysdale TA, Tonissen KF, Patterson KD. Cardiac troponin I is a heart-specific marker in the Xenopus embryo: expression during abnormal heart morphogenesis. Dev Biol 1994, 165:432-441.
10. Evans SM, Yan W, Murillo MP. tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman. Development 1995, 121:3889-3899.
11. Fu Y, Yan W, Mohun TJ. Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development 1998, 125:4439-4449.
12. Garriock RJ, Warkman AS, Meadows SM. Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16. Dev Dyn 2007, 236:1249-1258.
13. Grow MW, Krieg PA. Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5. Dev Biol 1998, 204:187-196.
14. Haworth KE, Kotecha S, Mohun TJ. GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos. BMC Dev Biol 2008, 8:74.
15. Hoppler S. Studying Wnt signaling in Xenopus. Methods Mol Biol 2008, 469:319-332.
16. Jiang Y, Evans T. The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Dev Biol 1996, 174:258-270.
17. Latinkic BV, Cooper B, Smith S. Transcriptional regulation of the cardiac-specific MLC2 gene during Xenopus embryonic development. Development 2004, 131:669-679.
18. Lavery DL, Hoppler S. Analysis of gene expression in Xenopus embryos. Methods Mol Biol 2008a, 469:335-361.
19. Lavery DL, Hoppler S. Gain-of-function and loss-of-function strategies in Xenopus. Methods Mol Biol 2008b, 469:401-415.
20. Lavery DL, Martin J, Turnbull YD. Wnt6 signaling regulates heart muscle development during organogenesis. Dev Biol 2008, 323:177-188.
21. Marvin MJ, Di Rocco G, Gardiner A. Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev 2001, 15:316-327.
22. Meijer L, Skaltsounis AL, Magiatis P. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol 2003, 10:1255-1266.
23. Molkentin JD, Antos C, Mercer B. Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart. Dev Biol 2000, 217:301-309.
24. Pandur P, Lasche M, Eisenberg LM. Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 2002, 418:636-641.
25. Patient RK, McGhee JD. The GATA family (vertebrates and invertebrates). Curr Opin Genet Dev 2002, 12:416-422.
26. Peterkin T, Gibson A, Patient R. GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation. EMBO J 2003, 22:4260-4273.
27. Peterkin T, Gibson A, Patient R. Redundancy and evolution of GATA factor requirements in development of the myocardium. Dev Biol 2007, 311:623-635.
28. Sakai Y, Nakagawa R, Sato R. Selection of DNA binding sites for human transcriptional regulator GATA-6. Biochem Biophys Res Commun 1998, 250:682-688.
29. Sasai Y, Lu B, Steinbeisser H, De Robertis EM. Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 1995, 376:333-336.
30. Sato N, Meijer L, Skaltsounis L. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004, 10:55-63.
31. Schneider VA, Mercola M. Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev 2001, 15:304-315.
32. Small EM, Warkman AS, Wang DZ, Sutherland LB, Olson EN, Krieg PA. Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. Development 2005, 132:987-997.
33. Sparrow DB, Cai C, Kotecha S. Regulation of the tinman homologues in Xenopus embryos. Dev Biol 2000, 227:65-79.
34. Tonissen KF, Drysdale TA, Lints TJ. XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development. Dev Biol 1994, 162:325-328.
35. Warkman AS, Atkinson BG. Amphibian cardiac troponin I gene's organization, developmental expression, and regulatory properties are different from its mammalian homologue. Dev Dyn 2004, 229:275-288.
36. Warkman AS, Krieg PA. Xenopus as a model system for vertebrate heart development. Semin Cell Dev Biol 2007, 18:46-53.
37. Yost C, Torres M, Miller JR. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 1996, 10:1443-1454.