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Volumn 5, Issue 3, 2016, Pages 282-290

Concise Review: Epigenetic regulation of myogenesis in health and disease

Author keywords

Chromatin; Differentiation; Epigenetic; Gene expression; Histone deacetylase inhibitor; Histone marks; Muscular dystrophy; MyoD; Myogenesis; Pax7; Satellite cell; Skeletal muscle; Transcription

Indexed keywords

FOLLISTATIN; GIVINOSTAT; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE INHIBITOR; HISTONE H2AZ; MYOCYTE ENHANCER FACTOR 2; MYOD PROTEIN; MYOD1 PROTEIN; MYOGENIC FACTOR; MYOGENIC FACTOR 5; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN ARGININE METHYLTRANSFERASE; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR PAX7; TRANSCRIPTION FACTOR SNAIL; HISTONE DEACETYLASE; PAX7 PROTEIN, HUMAN;

EID: 84959421384     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2015-0266     Document Type: Review
Times cited : (88)

References (100)
  • 2
    • 0036744815 scopus 로고    scopus 로고
    • The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis
    • Conboy IM, Rando TA. The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev Cell 2002; 3: 397- 409.
    • (2002) Dev Cell , vol.3 , pp. 397-409
    • Conboy, I.M.1    Rando, T.A.2
  • 3
    • 33745762804 scopus 로고    scopus 로고
    • Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
    • Shinin V, Gayraud-Morel B, Gomès D et al. Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol 2006; 8: 677-687.
    • (2006) Nat Cell Biol , vol.8 , pp. 677-687
    • Shinin, V.1    Gayraud-Morel, B.2    Gomès, D.3
  • 4
    • 34249108083 scopus 로고    scopus 로고
    • Asymmetric self-renewal and commitment of satellite stem cells in muscle
    • Kuang S, Kuroda K, Le Grand F et al. Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell 2007; 129: 999-1010.
    • (2007) Cell , vol.129 , pp. 999-1010
    • Kuang, S.1    Kuroda, K.2    Le Grand, F.3
  • 5
    • 0028264320 scopus 로고
    • Primarymousemyoblast purification, characterization, and transplantation for cell-mediated gene therapy
    • RandoTA, BlauHM. Primarymousemyoblast purification, characterization, and transplantation for cell-mediated gene therapy. J Cell Biol 1994; 125: 1275-1287.
    • (1994) J Cell Biol , vol.125 , pp. 1275-1287
    • Rando, T.A.1    Blau, H.M.2
  • 6
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • Spivakov M, Fisher AG. Epigenetic signatures of stem-cell identity. Nat Rev Genet 2007; 8: 263-271.
    • (2007) Nat Rev Genet , vol.8 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 7
    • 84879260661 scopus 로고    scopus 로고
    • A double take on bivalent promoters
    • Voigt P, Tee WW, Reinberg D. A double take on bivalent promoters. Genes Dev 2013; 27: 1318-1338.
    • (2013) Genes Dev , vol.27 , pp. 1318-1338
    • Voigt, P.1    Tee, W.W.2    Reinberg, D.3
  • 8
    • 84892440367 scopus 로고    scopus 로고
    • Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging
    • Liu L, Cheung TH, CharvilleGWet al. Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging. Cell Reports 2013; 4: 189-204.
    • (2013) Cell Reports , vol.4 , pp. 189-204
    • Liu, L.1    Cheung, T.H.2    Charville, G.W.3
  • 9
    • 79959349283 scopus 로고    scopus 로고
    • Genome-wide remodeling of the epigenetic landscape during myogenic differentiation
    • Asp P, Blum R, Vethantham V et al. Genome-wide remodeling of the epigenetic landscape during myogenic differentiation. Proc Natl Acad Sci USA 2011; 108: E149-E158.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. E149-E158
    • Asp, P.1    Blum, R.2    Vethantham, V.3
  • 10
    • 79955459714 scopus 로고    scopus 로고
    • Polycomb EZH2controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells
    • Juan AH, Derfoul A, Feng X et al. Polycomb EZH2controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells. Genes Dev 2011; 25: 789-794.
    • (2011) Genes Dev , vol.25 , pp. 789-794
    • Juan, A.H.1    Derfoul, A.2    Feng, X.3
  • 11
    • 84876076090 scopus 로고    scopus 로고
    • Ezh2 maintains a key phase of muscle satellite cell expansion but does not regulate terminal differentiation
    • Woodhouse S, Pugazhendhi D, Brien P et al. Ezh2 maintains a key phase of muscle satellite cell expansion but does not regulate terminal differentiation. J Cell Sci 2013; 126: 565-579.
    • (2013) J Cell Sci , vol.126 , pp. 565-579
    • Woodhouse, S.1    Pugazhendhi, D.2    Brien, P.3
  • 12
    • 84885340880 scopus 로고    scopus 로고
    • Pax7 is critical for the normal function of satellite cells in adult skeletal muscle
    • von Maltzahn J, Jones AE, Parks RJ et al. Pax7 is critical for the normal function of satellite cells in adult skeletal muscle. Proc Natl Acad Sci USA 2013; 110: 16474-16479.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 16474-16479
    • von Maltzahn, J.1    Jones, A.E.2    Parks, R.J.3
  • 13
    • 0034664770 scopus 로고    scopus 로고
    • Pax7 is required for the specification of myogenic satellite cells
    • Seale P, Sabourin LA, Girgis-Gabardo A et al. Pax7 is required for the specification of myogenic satellite cells. Cell 2000; 102: 777-786.
    • (2000) Cell , vol.102 , pp. 777-786
    • Seale, P.1    Sabourin, L.A.2    Girgis-Gabardo, A.3
  • 14
    • 84862139720 scopus 로고    scopus 로고
    • Transcriptional dominance of Pax7 in adult myogenesis isdue to high-affinity recognitionofhomeodomain motifs
    • Soleimani VD, Punch VG, Kawabe Y et al. Transcriptional dominance of Pax7 in adult myogenesis isdue to high-affinity recognitionofhomeodomain motifs. Dev Cell 2012; 22: 1208-1220.
    • (2012) Dev Cell , vol.22 , pp. 1208-1220
    • Soleimani, V.D.1    Punch, V.G.2    Kawabe, Y.3
  • 15
    • 37749009724 scopus 로고    scopus 로고
    • Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex
    • McKinnell IW, Ishibashi J, Le Grand F et al. Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex. Nat Cell Biol 2008; 10: 77-84.
    • (2008) Nat Cell Biol , vol.10 , pp. 77-84
    • McKinnell, I.W.1    Ishibashi, J.2    Le Grand, F.3
  • 16
    • 34247369851 scopus 로고    scopus 로고
    • A homeo-paired domain-binding motif directs Myf5 expression in progenitor cells of limb muscle
    • Buchberger A, Freitag D, Arnold HH. A homeo-paired domain-binding motif directs Myf5 expression in progenitor cells of limb muscle. Development 2007; 134: 1171-1180.
    • (2007) Development , vol.134 , pp. 1171-1180
    • Buchberger, A.1    Freitag, D.2    Arnold, H.H.3
  • 17
    • 4344705083 scopus 로고    scopus 로고
    • Myf5 expression in satellite cells and spindles in adult muscle is controlled by separate genetic elements
    • Zammit PS, Carvajal JJ, Golding JP et al. Myf5 expression in satellite cells and spindles in adult muscle is controlled by separate genetic elements. Dev Biol 2004; 273: 454-465.
    • (2004) Dev Biol , vol.273 , pp. 454-465
    • Zammit, P.S.1    Carvajal, J.J.2    Golding, J.P.3
  • 18
    • 79959273223 scopus 로고    scopus 로고
    • Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments
    • Ribas R, Moncaut N, Siligan C et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev Biol 2011; 355: 372-380.
    • (2011) Dev Biol , vol.355 , pp. 372-380
    • Ribas, R.1    Moncaut, N.2    Siligan, C.3
  • 19
    • 84866091538 scopus 로고    scopus 로고
    • Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions
    • Kawabe Y, Wang YX, McKinnell IW et al. Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions. Cell Stem Cell 2012; 11: 333-345.
    • (2012) Cell Stem Cell , vol.11 , pp. 333-345
    • Kawabe, Y.1    Wang, Y.X.2    McKinnell, I.W.3
  • 20
    • 58149295717 scopus 로고    scopus 로고
    • Protein arginine methylation in mammals: Who, what, and why
    • Bedford MT, Clarke SG. Protein arginine methylation in mammals: Who, what, and why. Mol Cell 2009; 33: 1-13.
    • (2009) Mol Cell , vol.33 , pp. 1-13
    • Bedford, M.T.1    Clarke, S.G.2
  • 21
    • 84863623509 scopus 로고    scopus 로고
    • Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules
    • Crist CG, Montarras D, Buckingham M. Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules. Cell Stem Cell 2012; 11: 118-126.
    • (2012) Cell Stem Cell , vol.11 , pp. 118-126
    • Crist, C.G.1    Montarras, D.2    Buckingham, M.3
  • 22
    • 84925955248 scopus 로고    scopus 로고
    • Post-transcriptional regulation of satellite cell quiescence by TTP-mediatedmRNAdecay
    • Hausburg MA, Doles JD, Clement SL et al. Post-transcriptional regulation of satellite cell quiescence by TTP-mediatedmRNAdecay. eLife 2015; 4: e03390.
    • (2015) eLife , vol.4
    • Hausburg, M.A.1    Doles, J.D.2    Clement, S.L.3
  • 23
    • 77951935861 scopus 로고    scopus 로고
    • Genome-wide MyoD binding in skeletal muscle cells: A potential for broad cellular reprogramming
    • Cao Y, Yao Z, SarkarDet al. Genome-wide MyoD binding in skeletal muscle cells: A potential for broad cellular reprogramming. Dev Cell 2010; 18: 662-674.
    • (2010) Dev Cell , vol.18 , pp. 662-674
    • Cao, Y.1    Yao, Z.2    Sarkar, D.3
  • 24
    • 84896858736 scopus 로고    scopus 로고
    • Roles of enhancer of zeste homolog 2: From skeletal muscle differentiation to rhabdomyosarcoma carcinogenesis
    • Marchesi I, Giordano A, Bagella L. Roles of enhancer of zeste homolog 2: From skeletal muscle differentiation to rhabdomyosarcoma carcinogenesis. Cell Cycle 2014; 13: 516-527.
    • (2014) Cell Cycle , vol.13 , pp. 516-527
    • Marchesi, I.1    Giordano, A.2    Bagella, L.3
  • 25
    • 77957357566 scopus 로고    scopus 로고
    • TNF/p38a/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
    • Palacios D, Mozzetta C, Consalvi S et al. TNF/p38a/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell 2010; 7: 455-469.
    • (2010) Cell Stem Cell , vol.7 , pp. 455-469
    • Palacios, D.1    Mozzetta, C.2    Consalvi, S.3
  • 26
    • 7544230144 scopus 로고    scopus 로고
    • The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
    • Caretti G, Di Padova M, Micales B et al. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev 2004; 18: 2627-2638.
    • (2004) Genes Dev , vol.18 , pp. 2627-2638
    • Caretti, G.1    Di Padova, M.2    Micales, B.3
  • 27
    • 70349764482 scopus 로고    scopus 로고
    • Mir- 214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells
    • Juan AH, Kumar RM, Marx JG et al. Mir- 214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells. Mol Cell 2009; 36: 61-74.
    • (2009) Mol Cell , vol.36 , pp. 61-74
    • Juan, A.H.1    Kumar, R.M.2    Marx, J.G.3
  • 28
    • 44349086037 scopus 로고    scopus 로고
    • MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis
    • Wong CF, Tellam RL. MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis. J Biol Chem 2008; 283: 9836-9843.
    • (2008) J Biol Chem , vol.283 , pp. 9836-9843
    • Wong, C.F.1    Tellam, R.L.2
  • 29
    • 77951428293 scopus 로고    scopus 로고
    • UTX mediates demethylation ofH3K27me3 atmusclespecific genes during myogenesis
    • Seenundun S, Rampalli S, Liu QC et al. UTX mediates demethylation ofH3K27me3 atmusclespecific genes during myogenesis. EMBO J 2010; 29: 1401-1411.
    • (2010) EMBO J , vol.29 , pp. 1401-1411
    • Seenundun, S.1    Rampalli, S.2    Liu, Q.C.3
  • 30
    • 79959835076 scopus 로고    scopus 로고
    • A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation
    • Verrier L, Escaffit F, Chailleux C et al. A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation. PLoS Genet 2011; 7: e1001390.
    • (2011) PLoS Genet , vol.7
    • Verrier, L.1    Escaffit, F.2    Chailleux, C.3
  • 31
    • 36849043170 scopus 로고    scopus 로고
    • p38MAPKsignaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation
    • Rampalli S, Li L, MakE et al. p38MAPKsignaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struct Mol Biol 2007; 14: 1150-1156.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 1150-1156
    • Rampalli, S.1    Li, L.2    Mak, E.3
  • 32
    • 0034067079 scopus 로고    scopus 로고
    • p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps
    • Wu Z, Woodring PJ, Bhakta KS et al. p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Mol Cell Biol 2000; 20: 3951-3964.
    • (2000) Mol Cell Biol , vol.20 , pp. 3951-3964
    • Wu, Z.1    Woodring, P.J.2    Bhakta, K.S.3
  • 33
    • 21644434750 scopus 로고    scopus 로고
    • The circuitry of a master switch: Myod and the regulation of skeletalmuscle gene transcription
    • Tapscott SJ. The circuitry of a master switch: Myod and the regulation of skeletalmuscle gene transcription. Development 2005; 132: 2685-2695.
    • (2005) Development , vol.132 , pp. 2685-2695
    • Tapscott, S.J.1
  • 34
    • 2942696668 scopus 로고    scopus 로고
    • MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis
    • Lee H, Habas R, Abate-Shen C. MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science 2004; 304: 1675-1678.
    • (2004) Science , vol.304 , pp. 1675-1678
    • Lee, H.1    Habas, R.2    Abate-Shen, C.3
  • 35
    • 84861302932 scopus 로고    scopus 로고
    • The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells
    • Wang J, Abate-Shen C. The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells. PLoS One 2012; 7: e37647.
    • (2012) PLoS One , vol.7
    • Wang, J.1    Abate-Shen, C.2
  • 36
    • 77958152990 scopus 로고    scopus 로고
    • Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors
    • Choi J, Jang H, Kim H et al. Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors. Biochem Biophys Res Commun 2010; 401: 327-332.
    • (2010) Biochem Biophys Res Commun , vol.401 , pp. 327-332
    • Choi, J.1    Jang, H.2    Kim, H.3
  • 37
    • 84883004255 scopus 로고    scopus 로고
    • Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation
    • Hamed M, Khilji S, Chen J et al. Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation. Sci Rep 2013; 3: 2390.
    • (2013) Sci Rep , vol.3 , pp. 2390
    • Hamed, M.1    Khilji, S.2    Chen, J.3
  • 38
    • 84864914697 scopus 로고    scopus 로고
    • Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiationspecific transcription in myogenesis
    • Soleimani VD, Yin H, Jahani-Asl A et al. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiationspecific transcription in myogenesis. Mol Cell 2012; 47: 457-468.
    • (2012) Mol Cell , vol.47 , pp. 457-468
    • Soleimani, V.D.1    Yin, H.2    Jahani-Asl, A.3
  • 39
    • 0037452764 scopus 로고    scopus 로고
    • MyoD is functionally linked to the silencing of a muscle-specific regulatory gene prior to skeletal myogenesis
    • Mal A, Harter ML. MyoD is functionally linked to the silencing of a muscle-specific regulatory gene prior to skeletal myogenesis. Proc Natl Acad Sci USA 2003; 100: 1735-1739.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1735-1739
    • Mal, A.1    Harter, M.L.2
  • 40
    • 34250311696 scopus 로고    scopus 로고
    • MyogeninandtheSWI/SNFATPaseBrg1maintain myogenic gene expression at different stages of skeletal myogenesis
    • Ohkawa Y, Yoshimura S, Higashi C et al. MyogeninandtheSWI/SNFATPaseBrg1maintain myogenic gene expression at different stages of skeletal myogenesis. J Biol Chem 2007; 282: 6564-6570.
    • (2007) J Biol Chem , vol.282 , pp. 6564-6570
    • Ohkawa, Y.1    Yoshimura, S.2    Higashi, C.3
  • 41
    • 32544460284 scopus 로고    scopus 로고
    • Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1
    • Ohkawa Y, Marfella CG, Imbalzano AN. Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1. EMBO J 2006; 25: 490-501.
    • (2006) EMBO J , vol.25 , pp. 490-501
    • Ohkawa, Y.1    Marfella, C.G.2    Imbalzano, A.N.3
  • 42
    • 33746511957 scopus 로고    scopus 로고
    • Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation
    • Mal AK. Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation. EMBO J 2006; 25: 3323-3334.
    • (2006) EMBO J , vol.25 , pp. 3323-3334
    • Mal, A.K.1
  • 43
    • 76149089145 scopus 로고    scopus 로고
    • p38-gamma-dependent gene silencing restricts entry into the myogenic differentiation program
    • Gillespie MA, Le Grand F, Scimè A et al. p38-gamma-dependent gene silencing restricts entry into the myogenic differentiation program. J Cell Biol 2009; 187: 991-1005.
    • (2009) J Cell Biol , vol.187 , pp. 991-1005
    • Gillespie, M.A.1    Le Grand, F.2    Scimè, A.3
  • 44
    • 0036787922 scopus 로고    scopus 로고
    • Association of class II histone deacetylases with heterochomatin protein 1: Potential role for histone methylation in control of muscle differentiation
    • Zhang CL, McKinsey TA, Olson EN. Association of class II histone deacetylases with heterochomatin protein 1: Potential role for histone methylation in control of muscle differentiation. Mol Cell Biol 2002; 22: 7302-7312.
    • (2002) Mol Cell Biol , vol.22 , pp. 7302-7312
    • Zhang, C.L.1    McKinsey, T.A.2    Olson, E.N.3
  • 45
    • 31944443463 scopus 로고    scopus 로고
    • MyoD recruits the cdk9/cyclin T2 complex on myogenicgenes regulatory regions
    • Giacinti C, Bagella L, Puri PL et al. MyoD recruits the cdk9/cyclin T2 complex on myogenicgenes regulatory regions. J Cell Physiol 2006; 206: 807-813.
    • (2006) J Cell Physiol , vol.206 , pp. 807-813
    • Giacinti, C.1    Bagella, L.2    Puri, P.L.3
  • 46
    • 17944376263 scopus 로고    scopus 로고
    • Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis
    • Puri PL, Iezzi S, Stiegler P et al. Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis. Mol Cell 2001; 8: 885-897.
    • (2001) Mol Cell , vol.8 , pp. 885-897
    • Puri, P.L.1    Iezzi, S.2    Stiegler, P.3
  • 47
    • 0034597816 scopus 로고    scopus 로고
    • Signaldependent nuclear export of a histone deacetylase regulates muscle differentiation
    • McKinsey TA, Zhang CL, Lu J et al. Signaldependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 2000; 408: 106-111.
    • (2000) Nature , vol.408 , pp. 106-111
    • McKinsey, T.A.1    Zhang, C.L.2    Lu, J.3
  • 48
    • 84929836984 scopus 로고    scopus 로고
    • Deconstruction of DNA methylation patterns during myogenesis reveals specific epigenetic events in the establishment of the skeletal muscle lineage
    • Carrió E, Díez-Villanueva A, Lois S et al. Deconstruction of DNA methylation patterns during myogenesis reveals specific epigenetic events in the establishment of the skeletal muscle lineage. STEM CELLS 2015; 33: 2025-2036.
    • (2015) STEM CELLS , vol.33 , pp. 2025-2036
    • Carrió, E.1    Díez-Villanueva, A.2    Lois, S.3
  • 49
    • 0018581647 scopus 로고
    • Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine
    • Taylor SM, Jones PA. Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 1979; 17: 771-779.
    • (1979) Cell , vol.17 , pp. 771-779
    • Taylor, S.M.1    Jones, P.A.2
  • 50
    • 0035134330 scopus 로고    scopus 로고
    • Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation
    • de la Serna IL, Carlson KA, Imbalzano AN. Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat Genet 2001; 27: 187-190.
    • (2001) Nat Genet , vol.27 , pp. 187-190
    • de la Serna, I.L.1    Carlson, K.A.2    Imbalzano, A.N.3
  • 51
    • 3042763342 scopus 로고    scopus 로고
    • p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
    • Simone C, Forcales SV, Hill DA et al. p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat Genet 2004; 36: 738-743.
    • (2004) Nat Genet , vol.36 , pp. 738-743
    • Simone, C.1    Forcales, S.V.2    Hill, D.A.3
  • 52
    • 84857190263 scopus 로고    scopus 로고
    • Signal-dependent incorporation of MyoDBAF60c into Brg1-based SWI/SNF chromatinremodelling complex
    • Forcales SV, Albini S, Giordani L et al. Signal-dependent incorporation of MyoDBAF60c into Brg1-based SWI/SNF chromatinremodelling complex. EMBOJ 2012; 31: 301-316.
    • (2012) EMBOJ , vol.31 , pp. 301-316
    • Forcales, S.V.1    Albini, S.2    Giordani, L.3
  • 53
    • 18144429118 scopus 로고    scopus 로고
    • MyoDtargets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex
    • de la Serna IL, Ohkawa Y, Berkes CA et al. MyoDtargets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex. Mol Cell Biol 2005; 25: 3997-4009.
    • (2005) Mol Cell Biol , vol.25 , pp. 3997-4009
    • de la Serna, I.L.1    Ohkawa, Y.2    Berkes, C.A.3
  • 54
    • 33845801596 scopus 로고    scopus 로고
    • The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling
    • DacwagCS, OhkawaY, Pal S et al. The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling. Mol Cell Biol 2007; 27: 384-394.
    • (2007) Mol Cell Biol , vol.27 , pp. 384-394
    • Dacwag, C.S.1    Ohkawa, Y.2    Pal, S.3
  • 55
    • 63049090097 scopus 로고    scopus 로고
    • Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation
    • DacwagCS, BedfordMT, Sif S et al. Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation. Mol Cell Biol 2009; 29: 1909-1921.
    • (2009) Mol Cell Biol , vol.29 , pp. 1909-1921
    • Dacwag, C.S.1    Bedford, M.T.2    Sif, S.3
  • 56
    • 84941042333 scopus 로고    scopus 로고
    • Spatial re-organization of myogenic regulatory sequences temporally controls gene expression
    • Harada A, Mallappa C, Okada S et al. Spatial re-organization of myogenic regulatory sequences temporally controls gene expression. Nucleic Acids Res 2015; 43: 2008-2021.
    • (2015) Nucleic Acids Res , vol.43 , pp. 2008-2021
    • Harada, A.1    Mallappa, C.2    Okada, S.3
  • 57
    • 78651092707 scopus 로고    scopus 로고
    • Myogenic transcriptional activation of MyoD mediated by replication-independent histone deposition
    • Yang JH, Song Y, Seol JH et al. Myogenic transcriptional activation of MyoD mediated by replication-independent histone deposition. Proc Natl Acad Sci USA 2011; 108: 85-90.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 85-90
    • Yang, J.H.1    Song, Y.2    Seol, J.H.3
  • 58
    • 84863812324 scopus 로고    scopus 로고
    • Chd2 interacts with H3. 3 to determine myogenic cell fate
    • Harada A, Okada S, Konno D et al. Chd2 interacts with H3. 3 to determine myogenic cell fate. EMBO J 2012; 31: 2994-3007.
    • (2012) EMBO J , vol.31 , pp. 2994-3007
    • Harada, A.1    Okada, S.2    Konno, D.3
  • 59
    • 37749051130 scopus 로고    scopus 로고
    • Epigenetic memory of an active gene state depends on histone H3. 3 incorporation into chromatin in the absence of transcription
    • Ng RK, Gurdon JB. Epigenetic memory of an active gene state depends on histone H3. 3 incorporation into chromatin in the absence of transcription. Nat Cell Biol 2008; 10: 102-109.
    • (2008) Nat Cell Biol , vol.10 , pp. 102-109
    • Ng, R.K.1    Gurdon, J.B.2
  • 60
    • 84941095996 scopus 로고    scopus 로고
    • Incorporation of histone H3. 1 suppresses the lineage potential of skeletal muscle
    • Harada A, Maehara K, Sato Y et al. Incorporation of histone H3. 1 suppresses the lineage potential of skeletal muscle. Nucleic Acids Res 2015; 43: 775-786.
    • (2015) Nucleic Acids Res , vol.43 , pp. 775-786
    • Harada, A.1    Maehara, K.2    Sato, Y.3
  • 61
    • 53549094681 scopus 로고    scopus 로고
    • Cathepsin L proteolytically processes histone H3 during mouse embryonic stemcell differentiation
    • Duncan EM, Muratore-Schroeder TL, Cook RG et al. Cathepsin L proteolytically processes histone H3 during mouse embryonic stemcell differentiation. Cell2008; 135: 284-294.
    • (2008) Cell , vol.135 , pp. 284-294
    • Duncan, E.M.1    Muratore-Schroeder, T.L.2    Cook, R.G.3
  • 62
    • 77953617931 scopus 로고    scopus 로고
    • Essential role of p18Hamlet/SRCAP-mediated histone H2A. Z chromatin incorporation in muscle differentiation
    • CuadradoA, Corrado N, Perdiguero E et al. Essential role of p18Hamlet/SRCAP-mediated histone H2A. Z chromatin incorporation in muscle differentiation. EMBO J 2010; 29: 2014-2025.
    • (2010) EMBO J , vol.29 , pp. 2014-2025
    • Cuadrado, A.1    Corrado, N.2    Perdiguero, E.3
  • 63
    • 84944441724 scopus 로고    scopus 로고
    • Ex vivo expansion and in vivo self-renewal of human muscle stem cells
    • Charville GW, Cheung TH, Yoo B et al. Ex vivo expansion and in vivo self-renewal of human muscle stem cells. Stem Cell Rep 2015; 5: 621-632.
    • (2015) Stem Cell Rep , vol.5 , pp. 621-632
    • Charville, G.W.1    Cheung, T.H.2    Yoo, B.3
  • 64
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • Seligson DB, Horvath S, Shi T et al. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 2005; 435: 1262-1266.
    • (2005) Nature , vol.435 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3
  • 65
    • 84860371953 scopus 로고    scopus 로고
    • Epigenetic protein families: A new frontier for drug discovery
    • Arrowsmith CH, Bountra C, Fish PV et al. Epigenetic protein families: A new frontier for drug discovery. Nat Rev Drug Discov 2012; 11: 384-400.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 384-400
    • Arrowsmith, C.H.1    Bountra, C.2    Fish, P.V.3
  • 66
    • 55749101363 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy
    • Lee MJ, Kim YS, Kummar S et al. Histone deacetylase inhibitors in cancer therapy. Curr Opin Oncol 2008; 20: 639-649.
    • (2008) Curr Opin Oncol , vol.20 , pp. 639-649
    • Lee, M.J.1    Kim, Y.S.2    Kummar, S.3
  • 68
    • 79957955613 scopus 로고    scopus 로고
    • HDAC inhibition in rheumatoid arthritis and juvenile idiopathic arthritis
    • Vojinovic J, Damjanov N. HDAC inhibition in rheumatoid arthritis and juvenile idiopathic arthritis. Mol Med 2011; 17: 397-403.
    • (2011) Mol Med , vol.17 , pp. 397-403
    • Vojinovic, J.1    Damjanov, N.2
  • 69
    • 84873636026 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Novel agents in cancer treatment
    • Glass E, Viale PH. Histone deacetylase inhibitors: Novel agents in cancer treatment. Clin J Oncol Nurs 2013; 17: 34-40.
    • (2013) Clin J Oncol Nurs , vol.17 , pp. 34-40
    • Glass, E.1    Viale, P.H.2
  • 70
    • 33749507982 scopus 로고    scopus 로고
    • Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors
    • Minetti GC, Colussi C, Adami Ret al. Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors. Nat Med 2006; 12: 1147-1150.
    • (2006) Nat Med , vol.12 , pp. 1147-1150
    • Minetti, G.C.1    Colussi, C.2    Adami, R.3
  • 71
    • 84892172072 scopus 로고    scopus 로고
    • Dystrophin complex functions as a scaffold for signalling proteins
    • Constantin B. Dystrophin complex functions as a scaffold for signalling proteins. Biochim Biophys Acta 2014; 1838: 635-642.
    • (2014) Biochim Biophys Acta , vol.1838 , pp. 635-642
    • Constantin, B.1
  • 72
    • 0037188532 scopus 로고    scopus 로고
    • Stagespecific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases
    • Iezzi S, Cossu G, Nervi C et al. Stagespecific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proc Natl Acad Sci USA 2002; 99: 7757-7762.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7757-7762
    • Iezzi, S.1    Cossu, G.2    Nervi, C.3
  • 73
    • 2342627231 scopus 로고    scopus 로고
    • Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin
    • Iezzi S, Di PadovaM, Serra C et al. Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Dev Cell 2004; 6: 673-684.
    • (2004) Dev Cell , vol.6 , pp. 673-684
    • Iezzi, S.1    Di Padova, M.2    Serra, C.3
  • 74
    • 17644389201 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
    • Ma K, Chan JK, Zhu G et al. Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation. Mol Cell Biol 2005; 25: 3575-3582.
    • (2005) Mol Cell Biol , vol.25 , pp. 3575-3582
    • Ma, K.1    Chan, J.K.2    Zhu, G.3
  • 75
    • 0033231604 scopus 로고    scopus 로고
    • Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program
    • Sartorelli V, Puri PL, Hamamori Y et al. Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program. Mol Cell 1999; 4: 725-734.
    • (1999) Mol Cell , vol.4 , pp. 725-734
    • Sartorelli, V.1    Puri, P.L.2    Hamamori, Y.3
  • 76
    • 0035794552 scopus 로고    scopus 로고
    • A role for histone deacetylase HDAC1 in modulating the transcriptional activity ofMyoD: Inhibition of the myogenic program
    • Mal A, Sturniolo M, Schiltz RL et al. A role for histone deacetylase HDAC1 in modulating the transcriptional activity ofMyoD: Inhibition of the myogenic program. EMBO J 2001; 20: 1739-1753.
    • (2001) EMBO J , vol.20 , pp. 1739-1753
    • Mal, A.1    Sturniolo, M.2    Schiltz, R.L.3
  • 77
    • 39449126788 scopus 로고    scopus 로고
    • Differentiation-dependent lysine 4 acetylation enhancesMEF2C binding to DNA in skeletal muscle cells
    • Angelelli C, Magli A, Ferrari D et al. Differentiation-dependent lysine 4 acetylation enhancesMEF2C binding to DNA in skeletal muscle cells. Nucleic Acids Res 2008; 36: 915-928.
    • (2008) Nucleic Acids Res , vol.36 , pp. 915-928
    • Angelelli, C.1    Magli, A.2    Ferrari, D.3
  • 78
    • 33750529352 scopus 로고    scopus 로고
    • Acetylation is important for MyoD function in adult mice
    • Duquet A, Polesskaya A, Cuvellier S et al. Acetylation is important for MyoD function in adult mice. EMBO Rep 2006; 7: 1140-1146.
    • (2006) EMBO Rep , vol.7 , pp. 1140-1146
    • Duquet, A.1    Polesskaya, A.2    Cuvellier, S.3
  • 79
    • 0034602180 scopus 로고    scopus 로고
    • CREB-binding protein/p300 activates MyoD by acetylation
    • Polesskaya A, Duquet A, Naguibneva I et al. CREB-binding protein/p300 activates MyoD by acetylation. J Biol Chem 2000; 275: 34359-34364.
    • (2000) J Biol Chem , vol.275 , pp. 34359-34364
    • Polesskaya, A.1    Duquet, A.2    Naguibneva, I.3
  • 80
    • 38049162263 scopus 로고    scopus 로고
    • MyoD acetylation influences temporal patterns of skeletal muscle gene expression
    • Di Padova M, Caretti G, Zhao P et al. MyoD acetylation influences temporal patterns of skeletal muscle gene expression. J Biol Chem 2007; 282: 37650-37659.
    • (2007) J Biol Chem , vol.282 , pp. 37650-37659
    • Di Padova, M.1    Caretti, G.2    Zhao, P.3
  • 81
    • 33846940901 scopus 로고    scopus 로고
    • Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2
    • Grégoire S, Xiao L, Nie J et al. Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2. Mol Cell Biol 2007; 27: 1280-1295.
    • (2007) Mol Cell Biol , vol.27 , pp. 1280-1295
    • Grégoire, S.1    Xiao, L.2    Nie, J.3
  • 82
    • 0037191752 scopus 로고    scopus 로고
    • Functional improvement of dystrophic muscle by myostatin blockade
    • Bogdanovich S, Krag TO, Barton ER et al. Functional improvement of dystrophic muscle by myostatin blockade. Nature 2002; 420: 418-421.
    • (2002) Nature , vol.420 , pp. 418-421
    • Bogdanovich, S.1    Krag, T.O.2    Barton, E.R.3
  • 83
    • 0036895736 scopus 로고    scopus 로고
    • Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
    • Wagner KR, McPherron AC, WinikN et al. Loss of myostatin attenuates severity of muscular dystrophy in mdx mice. Ann Neurol 2002; 52: 832-836.
    • (2002) Ann Neurol , vol.52 , pp. 832-836
    • Wagner, K.R.1    McPherron, A.C.2    Winik, N.3
  • 84
    • 38949123031 scopus 로고    scopus 로고
    • Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice
    • Nakatani M, Takehara Y, Sugino H et al. Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice. FASEB J 2008; 22: 477-487.
    • (2008) FASEB J , vol.22 , pp. 477-487
    • Nakatani, M.1    Takehara, Y.2    Sugino, H.3
  • 85
    • 21244489616 scopus 로고    scopus 로고
    • Improved success of myoblast transplantation in mdx mice by blocking the myostatin signal
    • Benabdallah BF, BouchentoufM, Tremblay JP. Improved success of myoblast transplantation in mdx mice by blocking the myostatin signal. Transplantation 2005; 79: 1696-1702.
    • (2005) Transplantation , vol.79 , pp. 1696-1702
    • Benabdallah, B.F.1    Bouchentouf, M.2    Tremblay, J.P.3
  • 86
    • 41949090708 scopus 로고    scopus 로고
    • Longterm enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors
    • Haidet AM, Rizo L, Handy C et al. Longterm enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors. Proc Natl Acad Sci USA 2008; 105: 4318-4322.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4318-4322
    • Haidet, A.M.1    Rizo, L.2    Handy, C.3
  • 87
    • 58049221125 scopus 로고    scopus 로고
    • HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment
    • Colussi C, Mozzetta C, Gurtner A et al. HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. Proc Natl Acad Sci USA 2008; 105: 19183-19187.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19183-19187
    • Colussi, C.1    Mozzetta, C.2    Gurtner, A.3
  • 88
    • 84878209746 scopus 로고    scopus 로고
    • Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat
    • Consalvi S, Mozzetta C, Bettica P et al. Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat. MolMed2013; 19: 79-87.
    • (2013) MolMed , vol.19 , pp. 79-87
    • Consalvi, S.1    Mozzetta, C.2    Bettica, P.3
  • 89
    • 84913616554 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: A potential epigenetic treatment for Duchenne muscular dystrophy
    • Consalvi S, Saccone V, Mozzetta C. Histone deacetylase inhibitors: a potential epigenetic treatment for Duchenne muscular dystrophy. Epigenomics 2014; 6: 547-560.
    • (2014) Epigenomics , vol.6 , pp. 547-560
    • Consalvi, S.1    Saccone, V.2    Mozzetta, C.3
  • 90
    • 79957933972 scopus 로고    scopus 로고
    • Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat)
    • Furlan A, Monzani V, Reznikov LL et al. Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). Mol Med 2011; 17: 353-362.
    • (2011) Mol Med , vol.17 , pp. 353-362
    • Furlan, A.1    Monzani, V.2    Reznikov, L.L.3
  • 91
    • 77952011904 scopus 로고    scopus 로고
    • Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice
    • Dumonceaux J, Marie S, Beley C et al. Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice. Mol Ther 2010; 18: 881-887.
    • (2010) Mol Ther , vol.18 , pp. 881-887
    • Dumonceaux, J.1    Marie, S.2    Beley, C.3
  • 92
    • 20144385858 scopus 로고    scopus 로고
    • Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice
    • Ryu H, Smith K, Camelo SI et al. Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice. J Neurochem 2005; 93: 1087-1098.
    • (2005) J Neurochem , vol.93 , pp. 1087-1098
    • Ryu, H.1    Smith, K.2    Camelo, S.I.3
  • 93
    • 10844284615 scopus 로고    scopus 로고
    • Benefit of valproic acid in suppressing disease progression of ALS model mice
    • Sugai F, Yamamoto Y, Miyaguchi K et al. Benefit of valproic acid in suppressing disease progression of ALS model mice. Eur J Neurosci 2004; 20: 3179-3183.
    • (2004) Eur J Neurosci , vol.20 , pp. 3179-3183
    • Sugai, F.1    Yamamoto, Y.2    Miyaguchi, K.3
  • 94
    • 79961028733 scopus 로고    scopus 로고
    • Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis
    • Yoo YE, Ko CP. Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. Exp Neurol 2011; 231: 147-159.
    • (2011) Exp Neurol , vol.231 , pp. 147-159
    • Yoo, Y.E.1    Ko, C.P.2
  • 95
    • 84903741666 scopus 로고    scopus 로고
    • Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA
    • Heinicke U, Fulda S. Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA. Cancer Lett 2014; 351: 50-58.
    • (2014) Cancer Lett , vol.351 , pp. 50-58
    • Heinicke, U.1    Fulda, S.2
  • 96
    • 84898597003 scopus 로고    scopus 로고
    • Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS
    • Ciarapica R, Carcarino E, Adesso L et al. Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS. BMC Cancer 2014; 14: 139.
    • (2014) BMC Cancer , vol.14 , pp. 139
    • Ciarapica, R.1    Carcarino, E.2    Adesso, L.3
  • 97
    • 84905868284 scopus 로고    scopus 로고
    • The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx)
    • Ciarapica R, De Salvo M, Carcarino E et al. The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx). Oncogene 2014; 33: 4173-4184.
    • (2014) Oncogene , vol.33 , pp. 4173-4184
    • Ciarapica, R.1    De Salvo, M.2    Carcarino, E.3
  • 98
    • 77957939315 scopus 로고    scopus 로고
    • TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: Implications in Duchenne muscular dystrophy
    • Acharyya S, Sharma SM, Cheng AS et al. TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: Implications in Duchenne muscular dystrophy. PLoS One 2010; 5: e12479.
    • (2010) PLoS One , vol.5
    • Acharyya, S.1    Sharma, S.M.2    Cheng, A.S.3
  • 100
    • 84983048296 scopus 로고    scopus 로고
    • Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy
    • Jones TI, King OD, Himeda CL et al. Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy. Clin Epigenet 2015; 7: 37.
    • (2015) Clin Epigenet , vol.7 , pp. 37
    • Jones, T.I.1    King, O.D.2    Himeda, C.L.3


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