Probing the promiscuity of ent-kaurene oxidases via combinatorial biosynthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 9, 2016, Pages 2526-2531

  Mafu, Sibongile ^a,b   Jia, Meirong ^a   Zi, Jiachen ^a,c   Morrone, Dana ^a,d   Wu, Yisheng ^a,e   Xu, Meimei ^a   Hillwig, Matthew L ^a,f   Peters, Reuben J ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JINAN UNIVERSITY   (China)

^d ST LOUIS COLLEGE OF PHARMACY   (United States)

^e Conagen Inc ^*  (United States)

^f SAINT VINCENT COLLEGE   (United States)

Author keywords

Cytochrome P450 monooxygenases; Enzyme specificity; Gibberellins; Labdane related diterpenoids; Natural products

Indexed keywords

CYTOCHROME P450; ENT KAURENE OXIDASE; GIBBERELLIN; OXIDOREDUCTASE; UNCLASSIFIED DRUG; ENT-KAURENE OXIDASE; MOLECULAR PROBE;

ARTICLE; ENZYME SPECIFICITY; ENZYME SYNTHESIS; HYDROXYLATION; METABOLIC ENGINEERING; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; BIOSYNTHESIS; ENZYMOLOGY; METABOLISM; MOLECULAR PROBE; PLANT;

CYTOCHROME P-450 ENZYME SYSTEM; GIBBERELLINS; MOLECULAR PROBES; PHYLOGENY; PLANTS; SUBSTRATE SPECIFICITY;

EID: 84959421243     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1512096113     Document Type: Article

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