메뉴 건너뛰기




Volumn 1, Issue , 2014, Pages

Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; SMALL INTERFERING RNA; VORINOSTAT;

EID: 84959396270     PISSN: None     EISSN: 20524463     Source Type: Journal    
DOI: 10.1038/sdata.2014.17     Document Type: Article
Times cited : (14)

References (28)
  • 1
    • 33845996135 scopus 로고    scopus 로고
    • Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
    • Duvic, M. et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 109, 31-39 (2007).
    • (2007) Blood , vol.109 , pp. 31-39
    • Duvic, M.1
  • 2
    • 34547683194 scopus 로고    scopus 로고
    • Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma
    • Olsen, E. A. et al. Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. J. Clin. Oncol. 25, 3109-3115 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 3109-3115
    • Olsen, E.A.1
  • 3
    • 45549083112 scopus 로고    scopus 로고
    • Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma
    • Fantin, V. R. et al. Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma. Cancer Res. 68, 3785-3794 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 3785-3794
    • Fantin, V.R.1
  • 4
    • 34249941680 scopus 로고    scopus 로고
    • Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
    • Lindemann, R. K. et al. Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma. Proc. Natl Acad. Sci. USA 104, 8071-8076 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 8071-8076
    • Lindemann, R.K.1
  • 5
    • 58049208190 scopus 로고    scopus 로고
    • Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitorinduced apoptosis
    • Fotheringham, S. et al. Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitorinduced apoptosis. Cancer Cell 15, 57-66 (2009).
    • (2009) Cancer Cell , vol.15 , pp. 57-66
    • Fotheringham, S.1
  • 6
    • 77950877402 scopus 로고    scopus 로고
    • HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy
    • Khan, O. et al. HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy. Proc. Natl Acad. Sci. USA 107, 6532-6537 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 6532-6537
    • Khan, O.1
  • 7
    • 78650290829 scopus 로고    scopus 로고
    • Using large-scale RNAi screens to identify novel drug targets for cancer
    • Nijwening, J. H., Beijersbergen, R. L. Using large-scale RNAi screens to identify novel drug targets for cancer. IDrugs 13, 772-777 (2010).
    • (2010) IDrugs , vol.13 , pp. 772-777
    • Nijwening, J.H.1    Beijersbergen, R.L.2
  • 8
    • 12144289681 scopus 로고    scopus 로고
    • A large-scale RNAi screen in human cells identifies new components of the p53 pathway
    • Berns, K. et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428, 431-437 (2004).
    • (2004) Nature , vol.428 , pp. 431-437
    • Berns, K.1
  • 9
    • 70349448673 scopus 로고    scopus 로고
    • Candidate biomarkers of response to an experimental cancer drug identified through a large-scale RNA interference genetic screen
    • Mullenders, J. et al. Candidate biomarkers of response to an experimental cancer drug identified through a large-scale RNA interference genetic screen. Clin. Cancer Res. 15, 5811-5819 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5811-5819
    • Mullenders, J.1
  • 10
    • 84883054675 scopus 로고    scopus 로고
    • Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation
    • Tandle, A. T. et al. Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation. Eur. J. Cancer 49, 3020-3028 (2013).
    • (2013) Eur. J. Cancer , vol.49 , pp. 3020-3028
    • Tandle, A.T.1
  • 11
    • 84877098603 scopus 로고    scopus 로고
    • A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer
    • Singel, S. M. et al. A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer. Clin. Cancer Res. 19, 2061-2070 (2013).
    • (2013) Clin. Cancer Res. , vol.19 , pp. 2061-2070
    • Singel, S.M.1
  • 12
    • 84881499406 scopus 로고    scopus 로고
    • A Genome-wide siRNA Screen identifies proteasome addiction as a vulnerability of Basal-like Triple-Negative breast cancer cells
    • Petrocca, F. et al. A Genome-wide siRNA Screen Identifies Proteasome Addiction as a Vulnerability of Basal-like Triple-Negative Breast Cancer Cells. Cancer Cell 24, 182-196 (2013).
    • (2013) Cancer Cell , vol.24 , pp. 182-196
    • Petrocca, F.1
  • 13
    • 84883325294 scopus 로고    scopus 로고
    • Depletion of RAD17 sensitizes pancreatic cancer cells to gemcitabine
    • Fredebohm, J., Wolf, J., Hoheisel, J. D., Boettcher, M. Depletion of RAD17 sensitizes pancreatic cancer cells to gemcitabine. J. Cell Sci. 126, 3380-3389 (2013).
    • (2013) J. Cell Sci. , vol.126 , pp. 3380-3389
    • Fredebohm, J.1    Wolf, J.2    Hoheisel, J.D.3    Boettcher, M.4
  • 14
    • 84872022032 scopus 로고    scopus 로고
    • A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells
    • Xie, L. et al. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. PLoS Genet. 8, e1003151 (2012).
    • (2012) PLoS Genet. , vol.8 , pp. e1003151
    • Xie, L.1
  • 15
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
    • MacKeigan, J. P., Murphy, L. O., Blenis, J. Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Bio. 7, 591-600 (2005).
    • (2005) Nat. Cell Bio. , vol.7 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 16
    • 84922330496 scopus 로고    scopus 로고
    • A High-throughput, multiplex cell death assay using an RNAi screening approach
    • Falkenberg, K., Saunders, D., Simpson, K. A High-throughput, multiplex cell death assay using an RNAi screening approach. Cold Spring Harb. Protoc. 2014, doi:10.1101/pdb.prot080267 (2014).
    • (2014) Cold Spring Harb. Protoc. , vol.2014
    • Falkenberg, K.1    Saunders, D.2    Simpson, K.3
  • 17
    • 68349112682 scopus 로고    scopus 로고
    • Statistical methods for analysis of high-throughput RNA interference screens
    • Birmingham, A. et al. Statistical methods for analysis of high-throughput RNA interference screens. Nat. Methods 6, 569-575 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 569-575
    • Birmingham, A.1
  • 18
    • 51049121572 scopus 로고    scopus 로고
    • Identification of genes that regulate epithelial cell migration using an siRNA screening approach
    • Simpson, K. J. et al. Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nat. Cell Bio. 10, 1027-1038 (2008).
    • (2008) Nat. Cell Bio. , vol.10 , pp. 1027-1038
    • Simpson, K.J.1
  • 19
    • 78149465975 scopus 로고    scopus 로고
    • A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
    • Chia, N. Y. et al. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468, 316-320 (2010).
    • (2010) Nature , vol.468 , pp. 316-320
    • Chia, N.Y.1
  • 20
    • 77649248469 scopus 로고    scopus 로고
    • Genome-wide siRNA screen identifies SMCX, EP400, Brd4 as E2-dependent regulators of human papillomavirus oncogene expression
    • Smith, J. A. et al. Genome-wide siRNA screen identifies SMCX, EP400, Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. Proc. Natl Acad. Sci. USA 107, 3752-3757 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 3752-3757
    • Smith, J.A.1
  • 21
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
    • Trapnell, C. et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat. Protoc. 7, 562-578 (2012).
    • (2012) Nat. Protoc. , vol.7 , pp. 562-578
    • Trapnell, C.1
  • 23
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M. D., McCarthy, D. J., Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 24
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Smyth, G. K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Molec. Biol. 3, Article3 (2004).
    • (2004) Stat. Appl. Genet. Molec. Biol. , vol.3
    • Smyth, G.K.1
  • 25
    • 84896735766 scopus 로고    scopus 로고
    • Voom: Precision weights unlock linear model analysis tools for RNA-seq read counts
    • Law, C. W., Chen, Y., Shi, W., Smyth, G. K. Voom: precision weights unlock linear model analysis tools for RNA-seq read counts. Genome Biol. 15, R29 (2014).
    • (2014) Genome Biol. , vol.15 , pp. R29
    • Law, C.W.1    Chen, Y.2    Shi, W.3    Smyth, G.K.4
  • 26
    • 39349097864 scopus 로고    scopus 로고
    • Identification of host proteins required for HIV infection through a functional genomic screen
    • Brass, A. L. et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 319, 921-926 (2008).
    • (2008) Science , vol.319 , pp. 921-926
    • Brass, A.L.1
  • 27
    • 84857781943 scopus 로고    scopus 로고
    • A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response
    • Adamson, B., Smogorzewska, A., Sigoillot, F. D., King, R. W., Elledge, S. J. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat. Cell Bio. 14, 318-328 (2012).
    • (2012) Nat. Cell Bio. , vol.14 , pp. 318-328
    • Adamson, B.1    Smogorzewska, A.2    Sigoillot, F.D.3    King, R.W.4    Elledge, S.J.5
  • 28
    • 28644449917 scopus 로고    scopus 로고
    • How does gene expression clustering work?
    • D'Haeseleer, P. How does gene expression clustering work? Nature Biotechnol. 23, 1499-1501 (2005).
    • (2005) Nature Biotechnol. , vol.23 , pp. 1499-1501
    • D'Haeseleer, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.