-
1
-
-
79954631518
-
Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
-
CrossRef Medline
-
Alvarez-Erviti L, Seow Y, Schapira AH, Gardiner C, Sargent IL, Wood MJ, Cooper JM (2011) Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. Neurobiol Dis 42:360 -367. CrossRef Medline
-
(2011)
Neurobiol Dis
, vol.42
, pp. 360-367
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Schapira, A.H.3
Gardiner, C.4
Sargent, I.L.5
Wood, M.J.6
Cooper, J.M.7
-
2
-
-
0027730175
-
Cytoplasmic dyneindependent vesicular transport from early to late endosomes
-
CrossRef Medline
-
Aniento F, Emans N, Griffiths G, Gruenberg J (1993) Cytoplasmic dyneindependent vesicular transport from early to late endosomes. J Cell Biol 123:1373-1387. CrossRef Medline
-
(1993)
J Cell Biol
, vol.123
, pp. 1373-1387
-
-
Aniento, F.1
Emans, N.2
Griffiths, G.3
Gruenberg, J.4
-
3
-
-
2442530398
-
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor
-
CrossRef Medline
-
Arighi CN, Hartnell LM, Aguilar RC, Haft CR, Bonifacino JS (2004) Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol 165:123-133. CrossRef Medline
-
(2004)
J Cell Biol
, vol.165
, pp. 123-133
-
-
Arighi, C.N.1
Hartnell, L.M.2
Aguilar, R.C.3
Haft, C.R.4
Bonifacino, J.S.5
-
4
-
-
84863206297
-
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
-
CrossRef Medline
-
Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, Ivarsson Y, Depoortere F, Coomans C, Vermeiren E, Zimmermann P, David G (2012) Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol 14:677- 685. CrossRef Medline
-
(2012)
Nat Cell Biol
, vol.14
, pp. 677-685
-
-
Baietti, M.F.1
Zhang, Z.2
Mortier, E.3
Melchior, A.4
Degeest, G.5
Geeraerts, A.6
Ivarsson, Y.7
Depoortere, F.8
Coomans, C.9
Vermeiren, E.10
Zimmermann, P.11
David, G.12
-
5
-
-
84880816067
-
Review series. Rab GTPases and membrane identity: Causal or inconsequential?
-
CrossRef Medline
-
Barr FA (2013) Review series. Rab GTPases and membrane identity: causal or inconsequential? J Cell Biol 202:191-199. CrossRef Medline
-
(2013)
J Cell Biol
, vol.202
, pp. 191-199
-
-
Barr, F.A.1
-
6
-
-
84903179483
-
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
-
CrossRef Medline
-
Bingol B, Tea JS, Phu L, Reichelt M, Bakalarski CE, Song Q, Foreman O, Kirkpatrick DS, Sheng M (2014) The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Nature 510:370 -375. CrossRef Medline
-
(2014)
Nature
, vol.510
, pp. 370-375
-
-
Bingol, B.1
Tea, J.S.2
Phu, L.3
Reichelt, M.4
Bakalarski, C.E.5
Song, Q.6
Foreman, O.7
Kirkpatrick, D.S.8
Sheng, M.9
-
7
-
-
79959976091
-
Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes
-
CrossRef Medline
-
Brankatschk B, Pons V, Parton RG, Gruenberg J (2011) Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes. PLoS One 6:e21771. CrossRef Medline
-
(2011)
PLoS One
, vol.6
-
-
Brankatschk, B.1
Pons, V.2
Parton, R.G.3
Gruenberg, J.4
-
8
-
-
0034057856
-
Rab7, a multifaceted GTP-binding protein regulating access to degradative compartments in eukaryotic cells
-
CrossRef
-
Bruckert F, Laurent O, Satre M (2000) Rab7, a multifaceted GTP-binding protein regulating access to degradative compartments in eukaryotic cells. Protoplasma 210:108 -116. CrossRef
-
(2000)
Protoplasma
, vol.210
, pp. 108-116
-
-
Bruckert, F.1
Laurent, O.2
Satre, M.3
-
9
-
-
0033999818
-
Rab7: A key to lysosome biogenesis
-
CrossRef Medline
-
Bucci C, Thomsen P, Nicoziani P, McCarthy J, van Deurs B (2000) Rab7: a key to lysosome biogenesis. Mol Biol Cell 11:467- 480. CrossRef Medline
-
(2000)
Mol Biol Cell
, vol.11
, pp. 467-480
-
-
Bucci, C.1
Thomsen, P.2
Nicoziani, P.3
McCarthy, J.4
van Deurs, B.5
-
10
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
CrossRef Medline
-
Chambers SM, Fasano CA, Papapetrou EP, Tomishima M, Sadelain M, Studer L (2009) Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol 27:275-280. CrossRef Medline
-
(2009)
Nat Biotechnol
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
Fasano, C.A.2
Papapetrou, E.P.3
Tomishima, M.4
Sadelain, M.5
Studer, L.6
-
11
-
-
61549111872
-
Alpha-Synuclein and neuronal cell death
-
CrossRef Medline
-
Cookson MR (2009) alpha-Synuclein and neuronal cell death. Mol Neurodegener 4:9. CrossRef Medline
-
(2009)
Mol Neurodegener
, vol.4
, pp. 9
-
-
Cookson, M.R.1
-
12
-
-
80055118968
-
Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
-
CrossRef Medline
-
Dragovic RA, Gardiner C, Brooks AS, Tannetta DS, Ferguson DJ, Hole P, Carr B, Redman CW, Harris AL, Dobson PJ, Harrison P, Sargent IL (2011) Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis. Nanomedicine 7:780 -788. CrossRef Medline
-
(2011)
Nanomedicine
, vol.7
, pp. 780-788
-
-
Dragovic, R.A.1
Gardiner, C.2
Brooks, A.S.3
Tannetta, D.S.4
Ferguson, D.J.5
Hole, P.6
Carr, B.7
Redman, C.W.8
Harris, A.L.9
Dobson, P.J.10
Harrison, P.11
Sargent, I.L.12
-
13
-
-
77952648551
-
Cell-produced alphasynuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival
-
CrossRef Medline
-
Emmanouilidou E, Melachroinou K, Roumeliotis T, Garbis SD, Ntzouni M, Margaritis LH, Stefanis L, Vekrellis K (2010) Cell-produced alphasynuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J Neurosci 30:6838-6851. CrossRef Medline
-
(2010)
J Neurosci
, vol.30
, pp. 6838-6851
-
-
Emmanouilidou, E.1
Melachroinou, K.2
Roumeliotis, T.3
Garbis, S.D.4
Ntzouni, M.5
Margaritis, L.H.6
Stefanis, L.7
Vekrellis, K.8
-
14
-
-
58149280810
-
In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101
-
CrossRef Medline
-
Falguières T, Luyet PP, Bissig C, Scott CC, Velluz MC, Gruenberg J (2008) In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101. Mol Biol Cell 19:4942- 4955. CrossRef Medline
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4942-4955
-
-
Falguières, T.1
Luyet, P.P.2
Bissig, C.3
Scott, C.C.4
Velluz, M.C.5
Gruenberg, J.6
-
15
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
CrossRef Medline
-
Fallon L, Bélanger CM, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, Voortman J, Haber M, Rouleau G, Thorarinsdottir T, Brice A, van Bergen En Henegouwen PM, Fon EA (2006) A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat Cell Biol 8:834-842. CrossRef Medline
-
(2006)
Nat Cell Biol
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Bélanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
Brice, A.11
van Bergen En Henegouwen, P.M.12
Fon, E.A.13
-
16
-
-
9444223942
-
Rab9 GTPase regulates late endosome size and requires effector interaction for its stability
-
CrossRef Medline
-
Ganley IG, Carroll K, Bittova L, Pfeffer S (2004) Rab9 GTPase regulates late endosome size and requires effector interaction for its stability. Mol Biol Cell 15:5420 -5430. CrossRef Medline
-
(2004)
Mol Biol Cell
, vol.15
, pp. 5420-5430
-
-
Ganley, I.G.1
Carroll, K.2
Bittova, L.3
Pfeffer, S.4
-
17
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkindependent manner upon induction of mitophagy
-
CrossRef Medline
-
Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW (2010) Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkindependent manner upon induction of mitophagy. Hum Mol Genet 19: 4861-4870. CrossRef Medline
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
18
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
CrossRef Medline
-
Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W (2010) PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 12:119 -131. CrossRef Medline
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
19
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
CrossRef Medline
-
Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428. CrossRef Medline
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
20
-
-
84910004657
-
LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity
-
CrossRef Medline
-
Gómez-Suaga P, Rivero-Ríos P, Fdez E, Blanca Ramírez M, Ferrer I, Aiastui A, López De Munain A, Hilfiker S (2014) LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity. Hum Mol Genet 23:6779-6796. CrossRef Medline
-
(2014)
Hum Mol Genet
, vol.23
, pp. 6779-6796
-
-
Gómez-Suaga, P.1
Rivero-Ríos, P.2
Fdez, E.3
Blanca Ramírez, M.4
Ferrer, I.5
Aiastui, A.6
López De Munain, A.7
Hilfiker, S.8
-
21
-
-
0025974686
-
rab5 controls early endosome fusion in vitro
-
CrossRef Medline
-
Gorvel JP, Chavrier P, Zerial M, Gruenberg J (1991) rab5 controls early endosome fusion in vitro. Cell 64:915-925. CrossRef Medline
-
(1991)
Cell
, vol.64
, pp. 915-925
-
-
Gorvel, J.P.1
Chavrier, P.2
Zerial, M.3
Gruenberg, J.4
-
22
-
-
0035490884
-
The endocytic pathway: A mosaic of domains
-
CrossRef Medline
-
Gruenberg J (2001) The endocytic pathway: a mosaic of domains. Nat Rev Mol Cell Biol 2:721-730. CrossRef Medline
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 721-730
-
-
Gruenberg, J.1
-
23
-
-
84924625546
-
Impaired intracellular trafficking defines early Parkinson's disease
-
CrossRef Medline
-
Hunn BH, Cragg SJ, Bolam JP, Spillantini MG, Wade-Martins R (2015) Impaired intracellular trafficking defines early Parkinson's disease. Trends Neurosci 38:178 -188. CrossRef Medline
-
(2015)
Trends Neurosci
, vol.38
, pp. 178-188
-
-
Hunn, B.H.1
Cragg, S.J.2
Bolam, J.P.3
Spillantini, M.G.4
Wade-Martins, R.5
-
24
-
-
84867031150
-
Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
-
CrossRef Medline
-
Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, et al. (2012) Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain 5:35. CrossRef Medline
-
(2012)
Mol Brain
, vol.5
, pp. 35
-
-
Imaizumi, Y.1
Okada, Y.2
Akamatsu, W.3
Koike, M.4
Kuzumaki, N.5
Hayakawa, H.6
Nihira, T.7
Kobayashi, T.8
Ohyama, M.9
Sato, S.10
Takanashi, M.11
Funayama, M.12
Hirayama, A.13
Soga, T.14
Hishiki, T.15
Suematsu, M.16
Yagi, T.17
Ito, D.18
Kosakai, A.19
Hayashi, K.20
more..
-
25
-
-
0035975946
-
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dyneindynactin motors
-
CrossRef Medline
-
Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, Janssen H, Wubbolts R, Neefjes J (2001) The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dyneindynactin motors. Curr Biol 11:1680 -1685. CrossRef Medline
-
(2001)
Curr Biol
, vol.11
, pp. 1680-1685
-
-
Jordens, I.1
Fernandez-Borja, M.2
Marsman, M.3
Dusseljee, S.4
Janssen, L.5
Calafat, J.6
Janssen, H.7
Wubbolts, R.8
Neefjes, J.9
-
26
-
-
82455179484
-
Systematic and quantitative assessment of the ubiquitin-modified proteome
-
CrossRef Medline
-
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell 44:325- 340. CrossRef Medline
-
(2011)
Mol Cell
, vol.44
, pp. 325-340
-
-
Kim, W.1
Bennett, E.J.2
Huttlin, E.L.3
Guo, A.4
Li, J.5
Possemato, A.6
Sowa, M.E.7
Rad, R.8
Rush, J.9
Comb, M.J.10
Harper, J.W.11
Gygi, S.P.12
-
27
-
-
84857038919
-
Movement disorders in 2011: Translating new research findings into clinical practice
-
CrossRef Medline
-
Klein C, Krainc D (2012) Movement disorders in 2011: translating new research findings into clinical practice. Nat Rev Neurol 8:65- 66. CrossRef Medline
-
(2012)
Nat Rev Neurol
, vol.8
, pp. 65-66
-
-
Klein, C.1
Krainc, D.2
-
28
-
-
0034108631
-
The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells
-
CrossRef Medline
-
Kobayashi T, Vischer UM, Rosnoblet C, Lebrand C, Lindsay M, Parton RG, Kruithof EK, Gruenberg J (2000) The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. Mol Biol Cell 11:1829 -1843. CrossRef Medline
-
(2000)
Mol Biol Cell
, vol.11
, pp. 1829-1843
-
-
Kobayashi, T.1
Vischer, U.M.2
Rosnoblet, C.3
Lebrand, C.4
Lindsay, M.5
Parton, R.G.6
Kruithof, E.K.7
Gruenberg, J.8
-
29
-
-
84904657288
-
Biogenesis and secretion of exosomes
-
CrossRef Medline
-
Kowal J, Tkach M, Théry C (2014) Biogenesis and secretion of exosomes. Curr Opin Cell Biol 29:116 -125. CrossRef Medline
-
(2014)
Curr Opin Cell Biol
, vol.29
, pp. 116-125
-
-
Kowal, J.1
Tkach, M.2
Théry, C.3
-
30
-
-
84901751574
-
Ubiquitin is phosphorylated by PINK1 to activate parkin
-
CrossRef Medline
-
Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, Matsuda N (2014) Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 510:162-166. CrossRef Medline
-
(2014)
Nature
, vol.510
, pp. 162-166
-
-
Koyano, F.1
Okatsu, K.2
Kosako, H.3
Tamura, Y.4
Go, E.5
Kimura, M.6
Kimura, Y.7
Tsuchiya, H.8
Yoshihara, H.9
Hirokawa, T.10
Endo, T.11
Fon, E.A.12
Trempe, J.F.13
Saeki, Y.14
Tanaka, K.15
Matsuda, N.16
-
31
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
CrossRef Medline
-
Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, Yang L, Beal MF, Surmeier DJ, Kordower JH, Tabar V, Studer L (2011) Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480:547-551. CrossRef Medline
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
Shim, J.W.2
Piao, J.3
Ganat, Y.M.4
Wakeman, D.R.5
Xie, Z.6
Carrillo-Reid, L.7
Auyeung, G.8
Antonacci, C.9
Buch, A.10
Yang, L.11
Beal, M.F.12
Surmeier, D.J.13
Kordower, J.H.14
Tabar, V.15
Studer, L.16
-
32
-
-
84891398328
-
Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex
-
CrossRef Medline
-
Lachance V, Degrandmaison J, Marois S, Robitaille M, Génier S, Nadeau S, Angers S, Parent JL (2014) Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex. J Cell Sci 127:111- 123. CrossRef Medline
-
(2014)
J Cell Sci
, vol.127
, pp. 111-123
-
-
Lachance, V.1
Degrandmaison, J.2
Marois, S.3
Robitaille, M.4
Génier, S.5
Nadeau, S.6
Angers, S.7
Parent, J.L.8
-
33
-
-
84891300736
-
Ubiquitination increases parkin activity to promote autophagic alpha-synuclein clearance
-
CrossRef Medline
-
Lonskaya I, Desforges NM, Hebron ML, Moussa CE (2013) Ubiquitination increases parkin activity to promote autophagic alpha-synuclein clearance. PLoS One 8:e83914. CrossRef Medline
-
(2013)
PLoS One
, vol.8
-
-
Lonskaya, I.1
Desforges, N.M.2
Hebron, M.L.3
Moussa, C.E.4
-
34
-
-
84949257064
-
VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin
-
CrossRef Medline
-
Malik BR, Godena VK, Whitworth AJ (2015) VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin. Hum Mol Genet 24:6106-6117. CrossRef Medline
-
(2015)
Hum Mol Genet
, vol.24
, pp. 6106-6117
-
-
Malik, B.R.1
Godena, V.K.2
Whitworth, A.J.3
-
35
-
-
79960009804
-
Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies
-
CrossRef Medline
-
Mazzulli JR, Xu YH, Sun Y, Knight AL, McLean PJ, Caldwell GA, Sidransky E, Grabowski GA, Krainc D (2011) Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies. Cell 146:37-52. CrossRef Medline
-
(2011)
Cell
, vol.146
, pp. 37-52
-
-
Mazzulli, J.R.1
Xu, Y.H.2
Sun, Y.3
Knight, A.L.4
McLean, P.J.5
Caldwell, G.A.6
Sidransky, E.7
Grabowski, G.A.8
Krainc, D.9
-
36
-
-
84879637572
-
Integrated proteomic analysis of post-translational modifications by serial enrichment
-
CrossRef Medline
-
Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10: 634-637. CrossRef Medline
-
(2013)
Nat Methods
, vol.10
, pp. 634-637
-
-
Mertins, P.1
Qiao, J.W.2
Patel, J.3
Udeshi, N.D.4
Clauser, K.R.5
Mani, D.R.6
Burgess, M.W.7
Gillette, M.A.8
Jaffe, J.D.9
Carr, S.A.10
-
37
-
-
84955200036
-
Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages
-
CrossRef Medline
-
Mrakovic A, Kay JG, Furuya W, Brumell JH, Botelho RJ (2012) Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages. Traffic 13:1667-1679. CrossRef Medline
-
(2012)
Traffic
, vol.13
, pp. 1667-1679
-
-
Mrakovic, A.1
Kay, J.G.2
Furuya, W.3
Brumell, J.H.4
Botelho, R.J.5
-
38
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
CrossRef Medline
-
Narendra D, Tanaka A, Suen DF, Youle RJ (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183:795- 803. CrossRef Medline
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
39
-
-
84882254367
-
The role of autophagy in neurodegenerative disease
-
CrossRef Medline
-
Nixon RA (2013) The role of autophagy in neurodegenerative disease. Nat Med 19:983-997. CrossRef Medline
-
(2013)
Nat Med
, vol.19
, pp. 983-997
-
-
Nixon, R.A.1
-
40
-
-
84903823741
-
Endocytic Rabs in membrane trafficking and signaling
-
CrossRef Medline
-
Numrich J, Ungermann C (2014) Endocytic Rabs in membrane trafficking and signaling. Biol Chem 395:327-333. CrossRef Medline
-
(2014)
Biol Chem
, vol.395
, pp. 327-333
-
-
Numrich, J.1
Ungermann, C.2
-
41
-
-
79953136097
-
Rab27a and Rab27b control different steps of the exosome secretion pathway
-
sup 11-13. CrossRef Medline
-
Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C (2010) Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol 12:19 -30; sup 11-13. CrossRef Medline
-
(2010)
Nat Cell Biol
, vol.12
, pp. 19-30
-
-
Ostrowski, M.1
Carmo, N.B.2
Krumeich, S.3
Fanget, I.4
Raposo, G.5
Savina, A.6
Moita, C.F.7
Schauer, K.8
Hume, A.N.9
Freitas, R.P.10
Goud, B.11
Benaroch, P.12
Hacohen, N.13
Fukuda, M.14
Desnos, C.15
Seabra, M.C.16
Darchen, F.17
Amigorena, S.18
Moita, L.F.19
Thery, C.20
more..
-
42
-
-
76149086512
-
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
-
CrossRef Medline
-
Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010) FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J Cell Biol 188:253-269. CrossRef Medline
-
(2010)
J Cell Biol
, vol.188
, pp. 253-269
-
-
Pankiv, S.1
Alemu, E.A.2
Brech, A.3
Bruun, J.A.4
Lamark, T.5
Overvatn, A.6
Bjørkøy, G.7
Johansen, T.8
-
43
-
-
77952764666
-
Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence
-
CrossRef Medline
-
Peralta ER, Martin BC, Edinger AL (2010) Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence. J Biol Chem 285:16814 -16821. CrossRef Medline
-
(2010)
J Biol Chem
, vol.285
, pp. 16814-16821
-
-
Peralta, E.R.1
Martin, B.C.2
Edinger, A.L.3
-
45
-
-
84921369563
-
The roles of PINK1, parkin, and mitochon- drial fidelity in Parkinson's disease
-
CrossRef Medline
-
Pickrell AM, Youle RJ (2015) The roles of PINK1, parkin, and mitochon- drial fidelity in Parkinson's disease. Neuron 85:257-273. CrossRef Medline
-
(2015)
Neuron
, vol.85
, pp. 257-273
-
-
Pickrell, A.M.1
Youle, R.J.2
-
46
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
-
CrossRef Medline
-
Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L (2010) The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One 5:e10054. CrossRef Medline
-
(2010)
PLoS One
, vol.5
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
Pallanck, L.5
-
47
-
-
77951918362
-
Identification of the switch in early-to-late endosome transition
-
CrossRef Medline
-
Poteryaev D, Datta S, Ackema K, Zerial M, Spang A (2010) Identification of the switch in early-to-late endosome transition. Cell 141:497-508. CrossRef Medline
-
(2010)
Cell
, vol.141
, pp. 497-508
-
-
Poteryaev, D.1
Datta, S.2
Ackema, K.3
Zerial, M.4
Spang, A.5
-
48
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)- induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
CrossRef Medline
-
Rakovic A, Shurkewitsch K, Seibler P, Grünewald A, Zanon A, Hagenah J, Krainc D, Klein C (2013) Phosphatase and tensin homolog (PTEN)- induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J Biol Chem 288: 2223-2237. CrossRef Medline
-
(2013)
J Biol Chem
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grünewald, A.4
Zanon, A.5
Hagenah, J.6
Krainc, D.7
Klein, C.8
-
49
-
-
56149112942
-
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7
-
CrossRef Medline
-
Rojas R, van Vlijmen T, Mardones GA, Prabhu Y, Rojas AL, Mohammed S, Heck AJ, Raposo G, van der Sluijs P, Bonifacino JS (2008) Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol 183:513-526. CrossRef Medline
-
(2008)
J Cell Biol
, vol.183
, pp. 513-526
-
-
Rojas, R.1
van Vlijmen, T.2
Mardones, G.A.3
Prabhu, Y.4
Rojas, A.L.5
Mohammed, S.6
Heck, A.J.7
Raposo, G.8
van der Sluijs, P.9
Bonifacino, J.S.10
-
50
-
-
67449147361
-
Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis
-
CrossRef Medline
-
Romero Rosales K, Peralta ER, Guenther GG, Wong SY, Edinger AL (2009) Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis. Mol Biol Cell 20:2831-2840. CrossRef Medline
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2831-2840
-
-
Romero Rosales, K.1
Peralta, E.R.2
Guenther, G.G.3
Wong, S.Y.4
Edinger, A.L.5
-
51
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
CrossRef Medline
-
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, HarperJW (2013) Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 496:372-376. CrossRef Medline
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
Harper, J.W.7
-
52
-
-
84902010970
-
Endosome maturation, transport and functions
-
CrossRef Medline
-
Scott CC, Vacca F, Gruenberg J (2014) Endosome maturation, transport and functions. Semin Cell Dev Biol 31:2-10. CrossRef Medline
-
(2014)
Semin Cell Dev Biol
, vol.31
, pp. 2-10
-
-
Scott, C.C.1
Vacca, F.2
Gruenberg, J.3
-
53
-
-
0034662876
-
A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion
-
CrossRef Medline
-
Seals DF, Eitzen G, Margolis N, Wickner WT, Price A (2000) A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 97:9402-9407. CrossRef Medline
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 9402-9407
-
-
Seals, D.F.1
Eitzen, G.2
Margolis, N.3
Wickner, W.T.4
Price, A.5
-
54
-
-
69649083104
-
Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5
-
CrossRef Medline
-
Seaman MN, Harbour ME, Tattersall D, Read E, Bright N (2009) Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5. J Cell Sci 122:2371-2382. CrossRef Medline
-
(2009)
J Cell Sci
, vol.122
, pp. 2371-2382
-
-
Seaman, M.N.1
Harbour, M.E.2
Tattersall, D.3
Read, E.4
Bright, N.5
-
55
-
-
84923647965
-
Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
-
CrossRef Medline
-
Small SA, Petsko GA (2015) Retromer in Alzheimer disease, Parkinson disease and other neurological disorders. Nat Rev Neurosci 16:126 -132. CrossRef Medline
-
(2015)
Nat Rev Neurosci
, vol.16
, pp. 126-132
-
-
Small, S.A.1
Petsko, G.A.2
-
56
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
CrossRef Medline
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M (1997) Alpha-synuclein in Lewy bodies. Nature 388:839-840. CrossRef Medline
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
57
-
-
84909952796
-
ATP13A2/PARK9 regulates secretion of exosomes and alpha-synuclein
-
CrossRef Medline
-
Tsunemi T, Hamada K, Krainc D (2014) ATP13A2/PARK9 regulates secretion of exosomes and alpha-synuclein. J Neurosci 34:15281-15287. CrossRef Medline
-
(2014)
J Neurosci
, vol.34
, pp. 15281-15287
-
-
Tsunemi, T.1
Hamada, K.2
Krainc, D.3
-
58
-
-
66449123730
-
Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration
-
CrossRef Medline
-
Vanlandingham PA, Ceresa BP (2009) Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration. J Biol Chem 284:12110 -12124. CrossRef Medline
-
(2009)
J Biol Chem
, vol.284
, pp. 12110-12124
-
-
Vanlandingham, P.A.1
Ceresa, B.P.2
-
59
-
-
84919468220
-
Formation of alpha-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes
-
CrossRef Medline
-
Volpicelli-Daley LA, Gamble KL, Schultheiss CE, Riddle DM, West AB, Lee VM (2014) Formation of alpha-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes. Mol Biol Cell 25:4010-4023. CrossRef Medline
-
(2014)
Mol Biol Cell
, vol.25
, pp. 4010-4023
-
-
Volpicelli-Daley, L.A.1
Gamble, K.L.2
Schultheiss, C.E.3
Riddle, D.M.4
West, A.B.5
Lee, V.M.6
-
60
-
-
80054033461
-
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles
-
M111. 013284. CrossRef Medline
-
Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C (2011) A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Mol Cell Proteomics 10: M111. 013284. CrossRef Medline
-
(2011)
Mol Cell Proteomics
, vol.10
-
-
Wagner, S.A.1
Beli, P.2
Weinert, B.T.3
Nielsen, M.L.4
Cox, J.5
Mann, M.6
Choudhary, C.7
-
61
-
-
0036915823
-
Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rabinteracting lysosomal protein
-
CrossRef Medline
-
Wang T, Hong W (2002) Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rabinteracting lysosomal protein. Mol Biol Cell 13:4317- 4332. CrossRef Medline
-
(2002)
Mol Biol Cell
, vol.13
, pp. 4317-4332
-
-
Wang, T.1
Hong, W.2
-
62
-
-
0034735539
-
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion
-
CrossRef Medline
-
Wurmser AE, Sato TK, Emr SD (2000) New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol 151:551-562. CrossRef Medline
-
(2000)
J Cell Biol
, vol.151
, pp. 551-562
-
-
Wurmser, A.E.1
Sato, T.K.2
Emr, S.D.3
-
63
-
-
84898652320
-
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
-
CrossRef Medline
-
Yamano K, Fogel AI, Wang C, van der Bliek AM, Youle RJ (2014) Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. eLife 3:e01612. CrossRef Medline
-
(2014)
eLife
, vol.3
-
-
Yamano, K.1
Fogel, A.I.2
Wang, C.3
van der Bliek, A.M.4
Youle, R.J.5
-
64
-
-
84883602232
-
Alpha-Synuclein and neuronal cell death
-
CrossRef Medline
-
Yasuda T, Nakata Y, MochizukiH (2013) alpha-Synuclein and neuronal cell death. Mol Neurobiol 47:466-483. CrossRef Medline
-
(2013)
Mol Neurobiol
, vol.47
, pp. 466-483
-
-
Yasuda, T.1
Nakata, Y.2
Mochizuki, H.3
|