메뉴 건너뛰기




Volumn 4, Issue 12, 2015, Pages e270-

In vivo delivery of miR-34a sensitizes lung tumors to radiation through RAD51 regulation

Author keywords

miR 34a; Non small cell Lung cancer; RAD51; Radiation

Indexed keywords

MICRORNA 34A; RAD51 PROTEIN;

EID: 84959361832     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2015.47     Document Type: Article
Times cited : (65)

References (32)
  • 1
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers, JH (2001). Genome maintenance mechanisms for preventing cancer. Nature 411: 366-374.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 2
    • 0037115914 scopus 로고    scopus 로고
    • Homologous repair of DNA damage and tumorigenesis: The BRCA connection
    • Jasin, M (2002). Homologous repair of DNA damage and tumorigenesis: the BRCA connection. Oncogene 21: 8981-8993.
    • (2002) Oncogene , vol.21 , pp. 8981-8993
    • Jasin, M.1
  • 4
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA doublestrand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata, M, Sasaki, MS, Sonoda, E, Morrison, C, Hashimoto, M, Utsumi, H et al. (1998). Homologous recombination and non-homologous end-joining pathways of DNA doublestrand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J 17: 5497-5508.
    • (1998) EMBO J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6
  • 5
    • 0035853295 scopus 로고    scopus 로고
    • DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells
    • Arnaudeau, C, Lundin, C and Helleday, T (2001). DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells. J Mol Biol 307: 1235-1245.
    • (2001) J Mol Biol , vol.307 , pp. 1235-1245
    • Arnaudeau, C.1    Lundin, C.2    Helleday, T.3
  • 6
    • 0036185784 scopus 로고    scopus 로고
    • Roles for caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development
    • Rinaldo, C, Bazzicalupo, P, Ederle, S, Hilliard, M and La Volpe, A (2002). Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development. Genetics 160: 471-479.
    • (2002) Genetics , vol.160 , pp. 471-479
    • Rinaldo, C.1    Bazzicalupo, P.2    Ederle, S.3    Hilliard, M.4    La Volpe, A.5
  • 7
    • 84655170270 scopus 로고    scopus 로고
    • Knockdown of rad51 expression induces radiation- and chemo-sensitivity in osteosarcoma cells
    • Du, LQ, Wang, Y, Wang, H, Cao, J, Liu, Q and Fan, FY (2011). Knockdown of Rad51 expression induces radiation- and chemo-sensitivity in osteosarcoma cells. Med Oncol 28: 1481-1487.
    • (2011) Med Oncol , vol.28 , pp. 1481-1487
    • Du, L.Q.1    Wang, Y.2    Wang, H.3    Cao, J.4    Liu, Q.5    Fan, F.Y.6
  • 8
    • 84907285869 scopus 로고    scopus 로고
    • Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing rad51 expression
    • Mo, N, Lu, YK, Xie, WM, Liu, Y, Zhou, WX, Wang, HX et al. (2014). Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing Rad51 expression. Oncol Rep 32: 1905-1912.
    • (2014) Oncol Rep , vol.32 , pp. 1905-1912
    • Mo, N.1    Lu, Y.K.2    Xie, W.M.3    Liu, Y.4    Zhou, W.X.5    Wang, H.X.6
  • 9
    • 84896912382 scopus 로고    scopus 로고
    • Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation
    • Gasparini, P, Lovat, F, Fassan, M, Casadei, L, Cascione, L, Jacob, NK et al. (2014). Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation. Proc Natl Acad Sci USA 111: 4536-4541.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 4536-4541
    • Gasparini, P.1    Lovat, F.2    Fassan, M.3    Casadei, L.4    Cascione, L.5    Jacob, N.K.6
  • 10
    • 33645814188 scopus 로고    scopus 로고
    • P53 modulates homologous recombination by transcriptional regulation of the RAD51 gene
    • Arias-Lopez, C, Lazaro-Trueba, I, Kerr, P, Lord, CJ, Dexter, T, Iravani, M et al. (2006). p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene. EMBO Rep 7: 219-224.
    • (2006) EMBO Rep , vol.7 , pp. 219-224
    • Arias-Lopez, C.1    Lazaro-Trueba, I.2    Kerr, P.3    Lord, C.J.4    Dexter, T.5    Iravani, M.6
  • 11
    • 78449286445 scopus 로고    scopus 로고
    • Tumor cell kill by c-MYC depletion: Role of MYC-regulated genes that control DNA doublestrand break repair
    • Luoto, KR, Meng, AX, Wasylishen, AR, Zhao, H, Coackley, CL, Penn, LZ et al. (2010). Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA doublestrand break repair. Cancer Res 70: 8748-8759.
    • (2010) Cancer Res , vol.70 , pp. 8748-8759
    • Luoto, K.R.1    Meng, A.X.2    Wasylishen, A.R.3    Zhao, H.4    Coackley, C.L.5    Penn, L.Z.6
  • 12
    • 0029969418 scopus 로고    scopus 로고
    • P53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction
    • Stürzbecher, HW, Donzelmann, B, Henning, W, Knippschild, U and Buchhop, S (1996). p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO J 15: 1992-2002.
    • (1996) EMBO J , vol.15 , pp. 1992-2002
    • Stürzbecher, H.W.1    Donzelmann, B.2    Henning, W.3    Knippschild, U.4    Buchhop, S.5
  • 13
    • 84899865106 scopus 로고    scopus 로고
    • MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability
    • Choi, YE, Pan, Y, Park, E, Konstantinopoulos, P, De, S, D'Andrea, A et al. (2014). MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability. Elife 3: e02445.
    • (2014) Elife , vol.3
    • Choi, Y.E.1    Pan, Y.2    Park, E.3    Konstantinopoulos, P.4    De, S.5    D'Andrea, A.6
  • 14
    • 62649112876 scopus 로고    scopus 로고
    • A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53
    • Sur, S, Pagliarini, R, Bunz, F, Rago, C, Diaz, LA Jr, Kinzler, KW et al. (2009). A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53. Proc Natl Acad Sci USA 106: 3964-3969.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3964-3969
    • Sur, S.1    Pagliarini, R.2    Bunz, F.3    Rago, C.4    Diaz, L.A.5    Kinzler, K.W.6
  • 15
    • 58549114916 scopus 로고    scopus 로고
    • MiR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells
    • Li, N, Fu, H, Tie, Y, Hu, Z, Kong, W, Wu, Y et al. (2009). miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells. Cancer Lett 275: 44-53.
    • (2009) Cancer Lett , vol.275 , pp. 44-53
    • Li, N.1    Fu, H.2    Tie, Y.3    Hu, Z.4    Kong, W.5    Wu, Y.6
  • 16
    • 77955022405 scopus 로고    scopus 로고
    • Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
    • Wiggins, JF, Ruffino, L, Kelnar, K, Omotola, M, Patrawala, L, Brown, D et al. (2010). Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res 70: 5923-5930.
    • (2010) Cancer Res , vol.70 , pp. 5923-5930
    • Wiggins, J.F.1    Ruffino, L.2    Kelnar, K.3    Omotola, M.4    Patrawala, L.5    Brown, D.6
  • 17
    • 70849087385 scopus 로고    scopus 로고
    • MiR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer
    • Gallardo, E, Navarro, A, Viñolas, N, Marrades, RM, Diaz, T, Gel, B et al. (2009). miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis 30: 1903-1909.
    • (2009) Carcinogenesis , vol.30 , pp. 1903-1909
    • Gallardo, E.1    Navarro, A.2    Viñolas, N.3    Marrades, R.M.4    Diaz, T.5    Gel, B.6
  • 18
    • 84893628843 scopus 로고    scopus 로고
    • Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates
    • Kelnar, K, Peltier, HJ, Leatherbury, N, Stoudemire, J and Bader, AG (2014). Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates. Anal Chem 86: 1534-1542.
    • (2014) Anal Chem , vol.86 , pp. 1534-1542
    • Kelnar, K.1    Peltier, H.J.2    Leatherbury, N.3    Stoudemire, J.4    Bader, A.G.5
  • 19
    • 84869219338 scopus 로고    scopus 로고
    • MiR-34 - A microRNA replacement therapy is headed to the clinic
    • Bader, AG (2012). miR-34 - a microRNA replacement therapy is headed to the clinic. Front Genet 3: 120.
    • (2012) Front Genet , vol.3 , pp. 120
    • Bader, A.G.1
  • 20
    • 84881363206 scopus 로고    scopus 로고
    • Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway
    • Duan, W, Xu, Y, Dong, Y, Cao, L, Tong, J and Zhou, X (2013). Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway. J Radiat Res 54: 611-619.
    • (2013) J Radiat Res , vol.54 , pp. 611-619
    • Duan, W.1    Xu, Y.2    Dong, Y.3    Cao, L.4    Tong, J.5    Zhou, X.6
  • 21
    • 84855573221 scopus 로고    scopus 로고
    • MiR-34a expression, cell cycle arrest and cell death of malignant mesothelioma cells upon treatment with radiation, docetaxel or combination treatment
    • Ghawanmeh, T, Thunberg, U, Castro, J, Murray, F and Laytragoon-Lewin, N (2011). miR-34a expression, cell cycle arrest and cell death of malignant mesothelioma cells upon treatment with radiation, docetaxel or combination treatment. Oncology 81: 330-335.
    • (2011) Oncology , vol.81 , pp. 330-335
    • Ghawanmeh, T.1    Thunberg, U.2    Castro, J.3    Murray, F.4    Laytragoon-Lewin, N.5
  • 22
    • 79952482227 scopus 로고    scopus 로고
    • MiR-34a in age and tissue related radio-sensitivity and serum miR-34a as a novel indicator of radiation injury
    • Liu, C, Zhou, C, Gao, F, Cai, S, Zhang, C, Zhao, L et al. (2011). MiR-34a in age and tissue related radio-sensitivity and serum miR-34a as a novel indicator of radiation injury. Int J Biol Sci 7: 221-233.
    • (2011) Int J Biol Sci , vol.7 , pp. 221-233
    • Liu, C.1    Zhou, C.2    Gao, F.3    Cai, S.4    Zhang, C.5    Zhao, L.6
  • 23
    • 67649979858 scopus 로고    scopus 로고
    • The mir-34 microRNA is required for the DNA damage response in vivo in C. Elegans and in vitro in human breast cancer cells
    • Kato, M, Paranjape, T, Müller, RU, Ullrich, R, Nallur, S, Gillespie, E et al. (2009). The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells. Oncogene 28: 2419-2424.
    • (2009) Oncogene , vol.28 , pp. 2419-2424
    • Kato, M.1    Paranjape, T.2    Müller, R.U.3    Ullrich, R.4    Nallur, S.5    Gillespie, E.6
  • 24
    • 84890335663 scopus 로고    scopus 로고
    • MicroRNA-34a promotes DNA damage and mitotic catastrophe
    • Kofman, AV, Kim, J, Park, SY, Dupart, E, Letson, C, Bao, Y et al. (2013). microRNA-34a promotes DNA damage and mitotic catastrophe. Cell Cycle 12: 3500-3511.
    • (2013) Cell Cycle , vol.12 , pp. 3500-3511
    • Kofman, A.V.1    Kim, J.2    Park, S.Y.3    Dupart, E.4    Letson, C.5    Bao, Y.6
  • 25
    • 76249131820 scopus 로고    scopus 로고
    • Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination
    • Ransburgh, DJ, Chiba, N, Ishioka, C, Toland, AE and Parvin, JD (2010). Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination. Cancer Res 70: 988-995.
    • (2010) Cancer Res , vol.70 , pp. 988-995
    • Ransburgh, D.J.1    Chiba, N.2    Ishioka, C.3    Toland, A.E.4    Parvin, J.D.5
  • 26
    • 0032526320 scopus 로고    scopus 로고
    • Overexpression of rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation
    • Vispé, S, Cazaux, C, Lesca, C and Defais, M (1998). Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation. Nucleic Acids Res 26: 2859-2864.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2859-2864
    • Vispé, S.1    Cazaux, C.2    Lesca, C.3    Defais, M.4
  • 29
    • 79959805164 scopus 로고    scopus 로고
    • MiRWalk-database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • Dweep, H, Sticht, C, Pandey, P and Gretz, N (2011). miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform 44: 839-847.
    • (2011) J Biomed Inform , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 30
    • 84905489718 scopus 로고    scopus 로고
    • Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer
    • Cortez, MA, Valdecanas, D, Zhang, X, Zhan, Y, Bhardwaj, V, Calin, GA et al. (2014). Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer. Mol Ther 22: 1494-1503.
    • (2014) Mol Ther , vol.22 , pp. 1494-1503
    • Cortez, M.A.1    Valdecanas, D.2    Zhang, X.3    Zhan, Y.4    Bhardwaj, V.5    Calin, G.A.6
  • 31
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Cancer Genome Atlas Research Network (2014). Comprehensive molecular profiling of lung adenocarcinoma. Nature 511: 543-550.
    • (2014) Nature , vol.511 , pp. 543-550
  • 32
    • 0025788894 scopus 로고
    • A linear-quadratic model of cell survival considering both sublethal and potentially lethal radiation damage
    • Rutz, HP, Coucke, PA and Mirimanoff, RO (1991). A linear-quadratic model of cell survival considering both sublethal and potentially lethal radiation damage. Radiother Oncol 21: 273-276.
    • (1991) Radiother Oncol , vol.21 , pp. 273-276
    • Rutz, H.P.1    Coucke, P.A.2    Mirimanoff, R.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.